DE3261731D1 - Substituted trifluoromethylphenyltetrahydropyridines having anorectic activity, their preparation and pharmaceutical compositions containing them - Google Patents

Substituted trifluoromethylphenyltetrahydropyridines having anorectic activity, their preparation and pharmaceutical compositions containing them

Info

Publication number
DE3261731D1
DE3261731D1 DE8282400320T DE3261731T DE3261731D1 DE 3261731 D1 DE3261731 D1 DE 3261731D1 DE 8282400320 T DE8282400320 T DE 8282400320T DE 3261731 T DE3261731 T DE 3261731T DE 3261731 D1 DE3261731 D1 DE 3261731D1
Authority
DE
Germany
Prior art keywords
trifluoromethylphenyltetrahydropyridines
substituted
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282400320T
Other languages
English (en)
Inventor
Dino Nisato
Emilio Crisafulli
Alberto Bianchetti
Paolo Carminati
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Application granted granted Critical
Publication of DE3261731D1 publication Critical patent/DE3261731D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8282400320T 1981-03-11 1982-02-24 Substituted trifluoromethylphenyltetrahydropyridines having anorectic activity, their preparation and pharmaceutical compositions containing them Expired DE3261731D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8104890A FR2501682A1 (fr) 1981-03-11 1981-03-11 Trifluoromethylphenylpyridines a activite anorexigene, un procede de preparation et compositions pharmaceutiques en contenant

Publications (1)

Publication Number Publication Date
DE3261731D1 true DE3261731D1 (en) 1985-02-14

Family

ID=9256120

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282400320T Expired DE3261731D1 (en) 1981-03-11 1982-02-24 Substituted trifluoromethylphenyltetrahydropyridines having anorectic activity, their preparation and pharmaceutical compositions containing them

Country Status (20)

Country Link
US (2) US4472408A (de)
EP (1) EP0060176B1 (de)
JP (1) JPS57159766A (de)
AR (2) AR229174A1 (de)
AT (1) ATE11044T1 (de)
AU (1) AU547692B2 (de)
CA (1) CA1196643A (de)
DE (1) DE3261731D1 (de)
DK (1) DK152843C (de)
ES (3) ES8305329A1 (de)
FI (1) FI76786C (de)
FR (1) FR2501682A1 (de)
GR (1) GR79178B (de)
IE (1) IE52365B1 (de)
IL (1) IL65169A0 (de)
NO (1) NO158736C (de)
NZ (1) NZ199973A (de)
PT (1) PT74559B (de)
YU (2) YU50782A (de)
ZA (1) ZA821518B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2531707A1 (fr) * 1982-08-16 1984-02-17 Midy Spa Trifluoromethylphenyltetrahydropyridines substituees a activite anorexigene, un procede de preparation et compositions pharmaceutiques
DE3438394A1 (de) * 1984-10-19 1986-04-30 Merck Patent Gmbh, 6100 Darmstadt Pyridinderivate
HU198454B (en) * 1987-12-14 1989-10-30 Richter Gedeon Vegyeszet Process for production of new derivatives of tetrahydrospiridin and medical compositions containing these compounds
FR2639226B1 (fr) * 1988-11-18 1993-11-05 Sanofi Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles anxio-depressifs
FR2650505B1 (fr) * 1989-08-07 1994-06-03 Midy Spa Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles de la motricite intestinale
FR2672213B1 (fr) * 1991-02-05 1995-03-10 Sanofi Sa Utilisation de derives 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridiniques comme capteurs de radicaux libres.

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3125488A (en) * 1964-03-17 Method of inducing analgesia by
US3072648A (en) * 1963-01-08 X-phenyl-s
GB881894A (en) * 1958-04-22 1961-11-08 Paul Adriaan Jan Janssen Tetrahydropyridine derivatives
FR86403E (fr) * 1959-05-01 1966-02-04 May & Baker Ltd Nouveaux dérivés de la phényl-4 pipéridine et leur préparation
GB984364A (en) * 1961-07-28 1965-02-24 May & Baker Ltd Substituted piperidines and tetrahydropyridines
GB948071A (en) * 1959-05-01 1964-01-29 May & Baker Ltd New heterocyclic compounds
US3284457A (en) * 1964-01-17 1966-11-08 Degussa 1-lower alkyl-4-substituted phenyl-1, 2, 3, 6-tetrahydropyridines and acid addition salts
US3626066A (en) * 1967-12-13 1971-12-07 Robins Co Inc A H Arylpyridinyl-alkyl alcohol derivatives in compositions and methods for tranquilizing mammals
AT287711B (de) * 1968-06-25 1971-02-10 Boehringer Sohn Ingelheim Verfahren zur Herstellung von neuen 1-Alkyl-1,2,5,6-tetrahydro-3-pyridylmethyl-carbonsäureestern sowie deren Säureadditionssalzen und quaternären Ammoniumverbindungen
DE2101997A1 (en) * 1971-01-16 1972-08-03 Farbenfabriken Bayer AG, 509öfLeverkusen 1-benzyl-4-subst-tetrahydropyridines - useful as intermediates for pharmaceuticals
US4012374A (en) * 1975-09-29 1977-03-15 E. R. Squibb & Sons, Inc. 1-[[4-Phenyl-piperidinyl (or tetrahydropyridinyl)]alkyl]-2,6-piperidinedione and analogs
US4024151A (en) * 1975-09-29 1977-05-17 E. R. Squibb & Sons, Inc. 4-Phenylpiperidinyl (and 4-phenyl-tetrahydropyridinyl) alkylamino-oxoalkanoic acids
FR2416886A1 (fr) * 1978-02-08 1979-09-07 Roussel Uclaf Nouveaux derives de la 3-phenyl-tetrahydropyridine et leurs sels, procedes de preparation et application a titre de medicaments

Also Published As

Publication number Publication date
FI76786B (fi) 1988-08-31
US4472408A (en) 1984-09-18
DK105082A (da) 1982-09-12
AU547692B2 (en) 1985-10-31
DK152843B (da) 1988-05-24
IL65169A0 (en) 1982-05-31
ES8407023A1 (es) 1984-09-01
ES527456A0 (es) 1984-09-01
YU50782A (en) 1985-03-20
YU195484A (en) 1985-03-20
IE52365B1 (en) 1987-09-30
NO158736C (no) 1988-10-26
DK152843C (da) 1988-10-03
ZA821518B (en) 1983-01-26
AR228330A1 (es) 1983-02-15
AR229174A1 (es) 1983-06-30
NZ199973A (en) 1984-10-19
AU8111182A (en) 1982-09-16
JPH0435459B2 (de) 1992-06-11
PT74559A (fr) 1982-04-01
FR2501682A1 (fr) 1982-09-17
NO158736B (no) 1988-07-18
ATE11044T1 (de) 1985-01-15
ES510302A0 (es) 1983-04-01
GR79178B (de) 1984-10-02
CA1196643A (en) 1985-11-12
IE820455L (en) 1982-09-11
EP0060176A1 (de) 1982-09-15
NO820767L (no) 1982-09-13
ES518545A0 (es) 1984-03-01
JPS57159766A (en) 1982-10-01
FI820826L (fi) 1982-09-12
EP0060176B1 (de) 1985-01-02
FI76786C (fi) 1988-12-12
ES8403109A1 (es) 1984-03-01
FR2501682B1 (de) 1984-03-16
ES8305329A1 (es) 1983-04-01
US4602024A (en) 1986-07-22
PT74559B (fr) 1983-11-10

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee