DK365488A - Nye bensimidazolderivater, fremgangsmaade til fremstilling deraf og et farmaceutisk praeparat indeholdende dem - Google Patents

Nye bensimidazolderivater, fremgangsmaade til fremstilling deraf og et farmaceutisk praeparat indeholdende dem

Info

Publication number
DK365488A
DK365488A DK365488A DK365488A DK365488A DK 365488 A DK365488 A DK 365488A DK 365488 A DK365488 A DK 365488A DK 365488 A DK365488 A DK 365488A DK 365488 A DK365488 A DK 365488A
Authority
DK
Denmark
Prior art keywords
bensimidazold
procedures
derivatives
preparing
new
Prior art date
Application number
DK365488A
Other languages
Danish (da)
English (en)
Other versions
DK365488D0 (da
Inventor
Tomas Boerje Alminger
Rolf Alex Bergman
Hans Bundgaard
Per Lennart Lindberg
Gunnel Elisabeth Sunden
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE8604998A external-priority patent/SE8604998D0/xx
Priority claimed from SE8605551A external-priority patent/SE8605551D0/xx
Priority claimed from SE8704049A external-priority patent/SE8704049D0/xx
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of DK365488D0 publication Critical patent/DK365488D0/da
Publication of DK365488A publication Critical patent/DK365488A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK365488A 1986-11-21 1988-07-01 Nye bensimidazolderivater, fremgangsmaade til fremstilling deraf og et farmaceutisk praeparat indeholdende dem DK365488A (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE8604998A SE8604998D0 (sv) 1986-11-21 1986-11-21 Novel pharmacological compounds
SE8605551A SE8605551D0 (sv) 1986-12-23 1986-12-23 Novel pharmacological compounds
SE8704049A SE8704049D0 (sv) 1987-10-16 1987-10-16 Novel pharmacological compounds
PCT/SE1987/000546 WO1988003921A1 (en) 1986-11-21 1987-11-20 New benzimidazole derivatives a process for production thereof and a pharmaceutical composition containing the same

Publications (2)

Publication Number Publication Date
DK365488D0 DK365488D0 (da) 1988-07-01
DK365488A true DK365488A (da) 1988-07-01

Family

ID=27355365

Family Applications (1)

Application Number Title Priority Date Filing Date
DK365488A DK365488A (da) 1986-11-21 1988-07-01 Nye bensimidazolderivater, fremgangsmaade til fremstilling deraf og et farmaceutisk praeparat indeholdende dem

Country Status (24)

Country Link
EP (3) EP0279149B1 (no)
JP (1) JPH02500744A (no)
KR (1) KR890700125A (no)
AT (1) ATE84032T1 (no)
AU (1) AU612129B2 (no)
DE (1) DE3783356T2 (no)
DK (1) DK365488A (no)
EG (1) EG18379A (no)
ES (1) ES2052603T3 (no)
FI (1) FI892454A (no)
GR (1) GR3007385T3 (no)
HU (1) HU204814B (no)
IE (2) IE940326L (no)
IL (1) IL84504A (no)
IS (1) IS1565B (no)
LV (1) LV10954B (no)
MY (1) MY101784A (no)
NO (1) NO173998C (no)
NZ (2) NZ234564A (no)
PL (1) PL157655B1 (no)
PT (1) PT86186B (no)
RU (1) RU2062778C1 (no)
WO (1) WO1988003921A1 (no)
YU (1) YU47116B (no)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8801907D0 (sv) * 1988-05-20 1988-05-20 Haessle Ab Novel pharmacological compounds
KR920003928B1 (ko) * 1988-09-20 1992-05-18 히사미쯔세이야꾸 가부시기가이샤 신규의 디벤즈[b,e]옥세핀유도체
SE8804629D0 (sv) * 1988-12-22 1988-12-22 Ab Haessle New therapeutically active compounds
IE64199B1 (en) * 1988-12-22 1995-07-12 Haessle Ab Compound with gastric acid inhibitory effect and process for its preparation
US5274099A (en) * 1989-12-20 1993-12-28 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US5049674A (en) * 1989-12-20 1991-09-17 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US4965269A (en) * 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
SE9002206D0 (sv) 1990-06-20 1990-06-20 Haessle Ab New compounds
ATE184602T1 (de) * 1990-06-20 1999-10-15 Astra Ab Dialkoxypyridinylbenzimidazolderivate, verfahren zur herstellung und ihre pharmazeutische verwendung
CA2053527C (en) * 1990-10-17 2002-03-12 Takashi Sohda Pyridine derivatives, their production and use
SE9103776D0 (sv) * 1991-12-19 1991-12-19 Astra Ab New compounds
EP0604657B1 (en) * 1992-05-21 2000-01-12 Otsuka Pharmaceutical Factory, Inc. Phosphonic diester derivative
WO1994026279A1 (en) * 1993-05-18 1994-11-24 The Upjohn Company Bisphosphonate esters for treating gastric disorders
US6875872B1 (en) 1993-05-28 2005-04-05 Astrazeneca Compounds
JP2002510293A (ja) * 1997-05-30 2002-04-02 ドクター・レディーズ・リサーチ・ファウンデーション 抗潰瘍剤として新規なベンゾイミダゾール誘導体、それらの製造方法、及びそれらを含有する薬学的組成物
JP2001527083A (ja) * 1997-12-31 2001-12-25 ザ・ユニバーシティ・オブ・カンザス 第二級および第三級アミン含有薬剤の水溶性プロドラッグおよびその製造方法
WO2001044257A1 (en) * 1999-12-17 2001-06-21 Ariad Pharmaceuticals, Inc. Proton pump inhibitors
AU2001294228A1 (en) * 2000-10-12 2002-04-22 Takeda Chemical Industries Ltd. Benzimidazole compounds, process for producing the same and use thereof
US20040248941A1 (en) * 2001-09-25 2004-12-09 Keiji Kamiyama Benzimidazone compound, process for producing the same, and use thereof
PT1913009E (pt) * 2005-07-28 2010-06-25 Intervet Int Bv Novos (tio)carbamatos de benzimidazole com actividade antiparasitária e sua síntese
WO2016061190A1 (en) 2014-10-14 2016-04-21 The Board Of Trustees Of The Leland Stanford Junior University Method for treating neurodegenerative diseases
PL3390367T3 (pl) 2015-12-15 2021-03-08 The Board Of Trustees Of The Leland Stanford Junior University Sposób zapobiegania zaburzeniom poznawczym związanym z wiekiem i zapaleniu tkanki nerwowej lub ich leczenia
SG11202101285YA (en) 2018-08-06 2021-03-30 Univ Leland Stanford Junior 2-arylbenzimidazoles as ppargc1a activators for treating neurodegenerative diseases
WO2021033729A1 (ja) * 2019-08-20 2021-02-25 小野薬品工業株式会社 S1p5受容体作動活性を有する化合物の塩および結晶形

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (no) 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
JPS5836312B2 (ja) * 1978-08-21 1983-08-08 日本電信電話株式会社 通信用平衡ケ−ブル線路の障害位置測定方式
JPS5687818A (en) * 1979-12-19 1981-07-16 Ishikawajima Harima Heavy Ind Co Ltd Reflex type position detector
US4359465A (en) 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
JPS57137860A (en) * 1981-02-20 1982-08-25 Sumitomo Electric Ind Ltd Optical tachometer
JPS5999597A (ja) * 1982-11-30 1984-06-08 株式会社東芝 光学測定装置
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
JPS6020051U (ja) * 1983-07-19 1985-02-12 三洋電機株式会社 カセツト収納装置
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
IL76839A (en) * 1984-10-31 1988-08-31 Byk Gulden Lomberg Chem Fab Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds

Also Published As

Publication number Publication date
LV10954A (lv) 1995-12-20
EP0279149B1 (en) 1992-12-30
NO883229D0 (no) 1988-07-20
PT86186A (en) 1987-12-01
LV10954B (en) 1996-08-20
KR890700125A (ko) 1989-03-02
EP0332647A1 (en) 1989-09-20
IE940326L (en) 1988-05-21
NO173998B (no) 1993-11-22
IE873125L (en) 1988-05-21
NZ222495A (en) 1991-04-26
MY101784A (en) 1992-01-17
NZ234564A (en) 1991-04-26
HU204814B (en) 1992-02-28
ES2052603T3 (es) 1994-07-16
DK365488D0 (da) 1988-07-01
NO173998C (no) 1994-03-02
FI892454A0 (fi) 1989-05-19
EG18379A (en) 1992-11-30
ATE84032T1 (de) 1993-01-15
NO883229L (no) 1988-09-16
EP0279149A3 (en) 1988-08-31
AU612129B2 (en) 1991-07-04
GR3007385T3 (no) 1993-07-30
IS1565B (is) 1994-12-13
EP0510719A1 (en) 1992-10-28
HUT51269A (en) 1990-04-28
YU47116B (sh) 1994-12-28
AU8330287A (en) 1988-06-16
FI892454A (fi) 1989-05-19
PL157655B1 (pl) 1992-06-30
IL84504A (en) 1994-10-07
WO1988003921A1 (en) 1988-06-02
RU2062778C1 (ru) 1996-06-27
DE3783356T2 (de) 1993-04-15
DE3783356D1 (de) 1993-02-11
JPH02500744A (ja) 1990-03-15
IS3284A7 (is) 1988-05-22
PL268927A1 (en) 1989-01-23
YU211087A (en) 1988-12-31
IE61178B1 (en) 1994-10-05
EP0279149A2 (en) 1988-08-24
PT86186B (pt) 1990-08-31

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment