DK3453400T3 - Fremgangsmåder til forebyggelse eller behandling af visse forstyrrelser ved inhibering af binding af il-4 og/eller il-13 til deres respektive receptorer - Google Patents

Fremgangsmåder til forebyggelse eller behandling af visse forstyrrelser ved inhibering af binding af il-4 og/eller il-13 til deres respektive receptorer Download PDF

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Publication number
DK3453400T3
DK3453400T3 DK18197286.0T DK18197286T DK3453400T3 DK 3453400 T3 DK3453400 T3 DK 3453400T3 DK 18197286 T DK18197286 T DK 18197286T DK 3453400 T3 DK3453400 T3 DK 3453400T3
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DK
Denmark
Prior art keywords
respectors
procedures
preventing
inhibiting binding
treating certain
Prior art date
Application number
DK18197286.0T
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Danish (da)
English (en)
Inventor
Andreas Hohlbaum
Laurent Audoly
Beverly Koller
Original Assignee
Pieris Pharmaceuticals Gmbh
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pieris Pharmaceuticals Gmbh, Astrazeneca Ab filed Critical Pieris Pharmaceuticals Gmbh
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Publication of DK3453400T3 publication Critical patent/DK3453400T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/16Central respiratory analeptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Dispersion Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
DK18197286.0T 2011-12-13 2012-12-12 Fremgangsmåder til forebyggelse eller behandling af visse forstyrrelser ved inhibering af binding af il-4 og/eller il-13 til deres respektive receptorer DK3453400T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161570018P 2011-12-13 2011-12-13
EP12813295.8A EP2790719B1 (en) 2011-12-13 2012-12-12 Methods for preventing or treating certain disorders by inhibiting binding of il-4 and/or il-13 to their respective receptors.

Publications (1)

Publication Number Publication Date
DK3453400T3 true DK3453400T3 (da) 2021-04-06

Family

ID=47552959

Family Applications (2)

Application Number Title Priority Date Filing Date
DK18197286.0T DK3453400T3 (da) 2011-12-13 2012-12-12 Fremgangsmåder til forebyggelse eller behandling af visse forstyrrelser ved inhibering af binding af il-4 og/eller il-13 til deres respektive receptorer
DK12813295.8T DK2790719T3 (en) 2011-12-13 2012-12-12 Methods for preventing or treating certain diseases by inhibiting the binding of IL-4 and / or IL-13 to their respective receptors

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK12813295.8T DK2790719T3 (en) 2011-12-13 2012-12-12 Methods for preventing or treating certain diseases by inhibiting the binding of IL-4 and / or IL-13 to their respective receptors

Country Status (13)

Country Link
US (6) US9572863B2 (enExample)
EP (3) EP3842058B1 (enExample)
JP (5) JP6163162B2 (enExample)
CN (2) CN109432402B (enExample)
AU (1) AU2012350660B2 (enExample)
CA (1) CA2858962C (enExample)
DK (2) DK3453400T3 (enExample)
ES (2) ES2863410T3 (enExample)
HU (2) HUE054342T2 (enExample)
PL (2) PL3453400T3 (enExample)
SG (2) SG10201604566QA (enExample)
TR (1) TR201901826T4 (enExample)
WO (1) WO2013087660A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011263786B2 (en) 2010-06-08 2014-11-13 Astrazeneca Ab Tear lipocalin muteins binding IL-4 R alpha
WO2013087660A1 (en) * 2011-12-13 2013-06-20 Pieris Ag Methods for preventing or treating certain disorders by inhibiting binding of il-4 and/or il-13 to their respective receptors
CA2949405C (en) * 2014-05-22 2023-08-01 Pieris Pharmaceuticals Gmbh Novel specific-binding polypeptides and uses thereof
CA2988831A1 (en) 2015-07-15 2017-01-19 Pieris Pharmaceuticals Gmbh Novel proteins specific for lag-3
CN113372446A (zh) * 2016-06-08 2021-09-10 苏州康乃德生物医药有限公司 用于结合白细胞介素4受体的抗体
RU2019122482A (ru) 2017-01-18 2021-02-19 Пирис Фармасьютикалс Гмбх Мутеины липокалина с аффинностью связывания в отношении lag-3
CA3059731A1 (en) * 2017-04-21 2018-10-25 Kindred Biosciences, Inc. Il4/il13 receptor molecule for veterinary use
CN111494625B (zh) 2018-12-25 2022-06-21 江苏荃信生物医药股份有限公司 用于治疗il-4和/或il-13介导的信号转导相关的疾病的药物组合物
US20220168387A1 (en) * 2019-03-29 2022-06-02 Pieris Pharmaceuticals Gmbh Inhaled administration of lipocalin muteins
CA3133422A1 (en) * 2019-03-29 2020-10-08 Astrazeneca Ab Lipocalin mutein for treatment of asthma
TW202241490A (zh) 2020-12-18 2022-11-01 瑞典商阿斯特捷利康公司 用於治療氣喘之脂質運載蛋白突變蛋白乾粉配製物
CN115414467B (zh) * 2022-10-14 2023-06-06 中国人民解放军陆军军医大学第二附属医院 载脂蛋白d在制备治疗脑出血药物中的用途

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01215289A (ja) 1988-02-22 1989-08-29 Toa Nenryo Kogyo Kk 遺伝子組換えによる正常ヒト血清アルブミンaの製造方法
FR2649991B2 (fr) 1988-08-05 1994-03-04 Rhone Poulenc Sante Utilisation de derives stables du plasmide pkd1 pour l'expression et la secretion de proteines heterologues dans les levures du genre kluyveromyces
US5728553A (en) 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
DE4425255A1 (de) 1994-07-16 1996-01-18 Asta Medica Ag Formulierung zur inhalativen Applikation
US5908621A (en) 1995-11-02 1999-06-01 Schering Corporation Polyethylene glycol modified interferon therapy
US6446467B1 (en) 1997-07-29 2002-09-10 Physical Optics Corporation Monolithic glass light shaping diffuser and method for its production
DE19742706B4 (de) 1997-09-26 2013-07-25 Pieris Proteolab Ag Lipocalinmuteine
CN1170543C (zh) 1998-06-08 2004-10-13 弗·哈夫曼-拉罗切有限公司 PEG-IFN-α和三唑核苷在治疗慢性丙型肝炎中的用途
US6403564B1 (en) 1998-10-16 2002-06-11 Schering Corporation Ribavirin-interferon alfa combination therapy for eradicating detectable HCV-RNA in patients having chronic hepatitis C infection
DE19926068C1 (de) 1999-06-08 2001-01-11 Arne Skerra Muteine des Bilin-Bindungsproteins
DE10043509A1 (de) 2000-09-01 2002-03-14 Asta Medica Ag Feste Peptidzubereitungen für die Inhalation und deren Herstellung
EP1377306A1 (en) 2001-03-09 2004-01-07 Dyax Corp. Serum albumin binding moieties
WO2003029462A1 (en) 2001-09-27 2003-04-10 Pieris Proteolab Ag Muteins of human neutrophil gelatinase-associated lipocalin and related proteins
EP1430136A1 (en) 2001-09-27 2004-06-23 Pieris ProteoLab AG Muteins of apolipoprotein d
AU2003233583A1 (en) * 2002-05-24 2003-12-12 Agennix Incorporated Oral lactoferrin in the treatment of respiratory disorders
US7691970B2 (en) 2003-08-25 2010-04-06 Pieris Ag Muteins of a bilin-binding protein with affinity for a given target
WO2005019255A1 (en) 2003-08-25 2005-03-03 Pieris Proteolab Ag Muteins of tear lipocalin
RU2389796C2 (ru) 2003-08-29 2010-05-20 Аэровэнс, Инк. Модифицированный антагонист рецептора il-4 и предназначенный для его получения очищенный полинуклеотид
EP2899277A1 (en) 2004-11-26 2015-07-29 Pieris AG Compound with affinity for the cytotoxic T lymphocyte-associated antigen (CTLA-4)
WO2007038619A2 (en) 2005-09-27 2007-04-05 Amunix, Inc. Proteinaceous pharmaceuticals and uses thereof
US8598317B2 (en) 2006-03-20 2013-12-03 Technische Universitaet Muenchen Muteins of tear lipocalin with affinity for the T-cell coreceptor CD4
SG173332A1 (en) 2006-08-01 2011-08-29 Pieris Ag Muteins of tear lipocalin and methods for obtaining the same
CN101784280A (zh) * 2007-07-11 2010-07-21 艾罗文斯公司 药物多肽干粉气溶胶制剂及制备方法
AU2011263786B2 (en) 2010-06-08 2014-11-13 Astrazeneca Ab Tear lipocalin muteins binding IL-4 R alpha
WO2013087660A1 (en) * 2011-12-13 2013-06-20 Pieris Ag Methods for preventing or treating certain disorders by inhibiting binding of il-4 and/or il-13 to their respective receptors

Also Published As

Publication number Publication date
CN103998053B (zh) 2018-11-02
US20190030121A1 (en) 2019-01-31
US10016483B2 (en) 2018-07-10
AU2012350660A1 (en) 2014-07-03
EP2790719B1 (en) 2018-11-21
EP3842058A1 (en) 2021-06-30
US20210145934A1 (en) 2021-05-20
TR201901826T4 (tr) 2019-03-21
EP3453400B1 (en) 2021-01-20
CN103998053B9 (zh) 2020-07-21
US10398754B2 (en) 2019-09-03
JP6889201B2 (ja) 2021-06-18
SG11201402992SA (en) 2014-07-30
JP6163162B2 (ja) 2017-07-12
HUE042720T2 (hu) 2019-07-29
JP6725447B2 (ja) 2020-07-15
WO2013087660A1 (en) 2013-06-20
US10857202B2 (en) 2020-12-08
US9572863B2 (en) 2017-02-21
DK2790719T3 (en) 2019-02-11
ES2710384T3 (es) 2019-04-24
AU2012350660B2 (en) 2018-01-25
US20230021168A1 (en) 2023-01-19
EP3453400A1 (en) 2019-03-13
US11382951B2 (en) 2022-07-12
US20200009223A1 (en) 2020-01-09
HUE054342T2 (hu) 2021-08-30
PL3453400T3 (pl) 2021-08-09
EP3842058B1 (en) 2023-08-23
SG10201604566QA (en) 2016-07-28
CN109432402B (zh) 2022-04-29
JP2015505303A (ja) 2015-02-19
US20140357548A1 (en) 2014-12-04
JP2017149733A (ja) 2017-08-31
PL2790719T3 (pl) 2019-05-31
ES2863410T3 (es) 2021-10-11
JP2019116499A (ja) 2019-07-18
JP7441589B2 (ja) 2024-03-01
JP2020164532A (ja) 2020-10-08
US20170112900A1 (en) 2017-04-27
EP2790719A1 (en) 2014-10-22
CA2858962A1 (en) 2013-06-20
CN109432402A (zh) 2019-03-08
CA2858962C (en) 2023-09-05
CN103998053A (zh) 2014-08-20
JP2022084854A (ja) 2022-06-07

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