DK3444268T3 - Staphylococcus aureus-leukocidiner, terapeutiske sammensætninger og anvendelser deraf - Google Patents
Staphylococcus aureus-leukocidiner, terapeutiske sammensætninger og anvendelser deraf Download PDFInfo
- Publication number
- DK3444268T3 DK3444268T3 DK18196549.2T DK18196549T DK3444268T3 DK 3444268 T3 DK3444268 T3 DK 3444268T3 DK 18196549 T DK18196549 T DK 18196549T DK 3444268 T3 DK3444268 T3 DK 3444268T3
- Authority
- DK
- Denmark
- Prior art keywords
- leucocidins
- applications
- staphylococcus aureus
- therapeutic compositions
- therapeutic
- Prior art date
Links
- 241000191967 Staphylococcus aureus Species 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5035—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on sub-cellular localization
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56938—Staphylococcus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/305—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Micrococcaceae (F)
- G01N2333/31—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Micrococcaceae (F) from Staphylococcus (G)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- Dermatology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33155010P | 2010-05-05 | 2010-05-05 | |
EP16187485.4A EP3121191B1 (en) | 2010-05-05 | 2011-05-05 | Staphylococcus aureus leukocidins, therapeutic compositions, and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3444268T3 true DK3444268T3 (da) | 2022-01-31 |
Family
ID=44902083
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK18196549.2T DK3444268T3 (da) | 2010-05-05 | 2011-05-05 | Staphylococcus aureus-leukocidiner, terapeutiske sammensætninger og anvendelser deraf |
Country Status (21)
Country | Link |
---|---|
US (5) | US9783582B2 (da) |
EP (4) | EP2566519B1 (da) |
JP (4) | JP6031029B2 (da) |
KR (3) | KR20190133290A (da) |
CN (2) | CN103025352B (da) |
AU (5) | AU2011247989C1 (da) |
BR (1) | BR112012029521A2 (da) |
CA (2) | CA2798355C (da) |
DK (1) | DK3444268T3 (da) |
ES (2) | ES2605476T3 (da) |
HR (1) | HRP20220068T1 (da) |
HU (1) | HUE058787T2 (da) |
IL (2) | IL222874B (da) |
LT (1) | LT3444268T (da) |
MX (4) | MX364642B (da) |
MY (1) | MY165618A (da) |
PL (1) | PL3444268T3 (da) |
RU (2) | RU2677140C1 (da) |
SI (1) | SI3444268T1 (da) |
WO (1) | WO2011140337A2 (da) |
ZA (4) | ZA201208455B (da) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2677140C1 (ru) * | 2010-05-05 | 2019-01-15 | Нью-Йорк Юниверсити | Лейкоцидины staphylococcus aureus, терапевтические композиции и их применение |
LT3403669T (lt) * | 2011-06-19 | 2020-10-12 | New York University | Staphylococcus aureus infekcijų ir giminingų būklių gydymo bei prevencijos būdai |
EP2668208B1 (en) | 2012-04-17 | 2015-06-03 | ARSANIS Biosciences GmbH | Cross-reactive staphylococcus aureus antibody |
US9657103B2 (en) | 2012-05-02 | 2017-05-23 | New York University | Methods of treating and preventing Staphylococcus aureus infections and associated conditions |
KR101826538B1 (ko) * | 2012-05-30 | 2018-02-07 | 현대자동차 주식회사 | 차량용 글래스 몰딩 부착 장치 및 그 방법 |
WO2014187746A2 (en) * | 2013-05-21 | 2014-11-27 | Arsanis Biosciences Gmbh | Generation of highly potent antibodies neutralizing the lukgh (lukab) toxin of staphylococcus aureus |
WO2014205127A2 (en) | 2013-06-18 | 2014-12-24 | New York University | Cellular factors involved in the cytotoxicity of staphylococcus aureus leukocidins: novel therapeutic targets |
JP6473746B2 (ja) * | 2013-10-17 | 2019-02-20 | アルサニス・バイオサイエンスズ・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 交差反応性黄色ブドウ球菌抗体配列 |
MX2016007533A (es) | 2013-12-09 | 2016-12-14 | Univ New York | Composiciones y metodos para el suministro fagocitico de agentes anti-estafilococicos. |
CN106132988A (zh) * | 2013-12-19 | 2016-11-16 | 阿尔萨尼斯生物科学有限责任公司 | 抗金黄色葡萄球菌lukgh(lukab)毒素的抗体和抗体序列 |
JP2018517708A (ja) * | 2015-06-05 | 2018-07-05 | ニューヨーク・ユニバーシティ | 抗ブドウ球菌生物学的薬剤のための組成物及び方法 |
WO2018165089A1 (en) * | 2017-03-06 | 2018-09-13 | Vanderbilt University | Human monoclonal antibodies to staphylococcus aureus lukab toxin |
EP3638286A4 (en) * | 2017-06-13 | 2021-03-10 | Integrated Biotherapeutic Vaccines, Inc. | IMMUNOGENIC COMPOSITIONS CONTAINING POLYPEPTIDES DERIVED FROM LEUCOCIDINS LUKA AND LUKB OF STAPHYLOCOCCUS AUREUS |
KR102061735B1 (ko) * | 2018-06-08 | 2020-01-02 | 대한민국(농림축산식품부 농림축산검역본부장) | 황색포도알균 약독화 장독소 및 세포독소 재조합 단백질을 포함하는 백신 조성물 |
WO2020023644A2 (en) | 2018-07-24 | 2020-01-30 | Medimmune, Llc | Antibody directed against s. aureus clumping factor a (clfa) |
TW202035443A (zh) | 2018-10-09 | 2020-10-01 | 美商麥迪紐有限責任公司 | 抗金黃色葡萄球菌抗體的組合 |
WO2020076790A1 (en) * | 2018-10-09 | 2020-04-16 | Medimmune, Llc | Antibodies directed against staphylococcus aureus leukotoxins |
AU2020358862A1 (en) | 2019-10-02 | 2022-04-14 | Janssen Vaccines & Prevention B.V. | Staphylococcus peptides and methods of use |
EP4216982A2 (en) * | 2020-09-28 | 2023-08-02 | Janssen Pharmaceuticals, Inc. | Variant staphylococcusaureus luka and lukb polypeptides and vaccine compositions |
JP2024512751A (ja) * | 2021-04-02 | 2024-03-19 | ヤンセン ファーマシューティカルズ,インコーポレーテッド | Staphylococcus aureusワクチン組成物 |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
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US300A (en) | 1837-07-29 | Machine foe spinning woolen roving | ||
US400A (en) | 1837-09-25 | Mode of causing puppet valves to work lights | ||
RU2122862C1 (ru) * | 1995-12-08 | 1998-12-10 | Научно-исследовательский институт вакцин и сывороток им.И.И.Мечникова | Бесклеточная антистафилококковая вакцина для лечения хронической стафилококковой инфекции |
ES2321892T3 (es) | 1998-09-14 | 2009-06-12 | Nabi Biopharmaceuticals | Composiciones de beta-glucanos e inmunoglobulinas especificas. |
CA2404260A1 (en) | 2000-03-21 | 2001-09-27 | Elitra Pharmaceuticals, Inc. | Identification of essential genes in prokaryotes |
US6849259B2 (en) | 2000-06-16 | 2005-02-01 | Symphogen A/S | Polyclonal antibody composition for treating allergy |
AT410798B (de) * | 2001-01-26 | 2003-07-25 | Cistem Biotechnologies Gmbh | Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen |
GB0107661D0 (en) * | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
AU2003303301B2 (en) | 2002-05-03 | 2008-08-07 | Massachusetts Institute Of Technology | Delta4,5 glycuronidase and uses thereof |
CN102698261A (zh) | 2005-06-13 | 2012-10-03 | 葛兰素史密斯克蓝生物品公司 | Panton-valentine杀白细胞素用于治疗和预防葡萄球菌感染的用途 |
CN100485038C (zh) * | 2005-09-13 | 2009-05-06 | 四川大学华西医院 | 小型化抗耐药金黄色葡萄球菌多肽及其应用与制备方法 |
WO2007100580A2 (en) * | 2006-02-22 | 2007-09-07 | The Texas A & M University System | Antibodies recognizing a highly expressed putative antigen of ca-mrsa and methods of use |
CN101466406B (zh) * | 2006-06-12 | 2012-06-27 | 葛兰素史密斯克蓝生物品公司 | α-毒素在治疗和预防葡萄球菌感染上的用途 |
CN101535811B (zh) | 2006-10-18 | 2016-05-04 | 生物梅里埃公司 | 用于体外诊断产pvl金黄色葡萄球菌的方法 |
GB0624340D0 (en) * | 2006-12-06 | 2007-01-17 | Nature Therapeutics Ltd | Antimicrobial composition |
WO2009029831A1 (en) * | 2007-08-31 | 2009-03-05 | University Of Chicago | Methods and compositions related to immunizing against staphylococcal lung diseases and conditions |
JP2011500036A (ja) | 2007-10-15 | 2011-01-06 | ザ ユニバーシティー オブ クイーンズランド | 構築物系およびその使用 |
CN101182350A (zh) * | 2007-11-02 | 2008-05-21 | 山东省农业科学院奶牛研究中心 | 金黄色葡萄球菌α-溶血素及其编码序列 |
WO2009111177A2 (en) * | 2008-03-05 | 2009-09-11 | Mount Sinai School Of Medicine Of New York University | Compositions and methods comprising genetically enhanced obligate and facultative anaerobic bacteria for oncopathic cancer therapy |
EP2291196A4 (en) * | 2008-05-12 | 2012-05-30 | Strox Biopharmaceuticals Llc | FOR STAPHYLOCOCCUS AUREUS SPECIFIC ANTIBODY PREPARATIONS |
CN102203125A (zh) | 2008-08-25 | 2011-09-28 | 安普利穆尼股份有限公司 | Pd-1拮抗剂及其使用方法 |
JP5792621B2 (ja) | 2008-09-26 | 2015-10-14 | オンコメッド ファーマシューティカルズ インコーポレイテッド | frizzled結合剤およびその使用 |
SG175092A1 (en) * | 2009-04-14 | 2011-11-28 | Novartis Ag | Compositions for immunising against staphylococcus aerus |
RU2677140C1 (ru) * | 2010-05-05 | 2019-01-15 | Нью-Йорк Юниверсити | Лейкоцидины staphylococcus aureus, терапевтические композиции и их применение |
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2011
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- 2011-05-05 US US13/696,245 patent/US9783582B2/en active Active - Reinstated
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- 2011-05-05 DK DK18196549.2T patent/DK3444268T3/da active
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- 2011-05-05 RU RU2012152086A patent/RU2644237C2/ru active
- 2011-05-05 ES ES11778343.1T patent/ES2605476T3/es active Active
- 2011-05-05 CN CN201180033386.0A patent/CN103025352B/zh active Active
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- 2011-05-05 HR HRP20220068TT patent/HRP20220068T1/hr unknown
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- 2011-05-05 KR KR1020187036903A patent/KR102050078B1/ko active IP Right Grant
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- 2011-05-05 MX MX2015016666A patent/MX364642B/es unknown
- 2011-05-05 BR BR112012029521-7A patent/BR112012029521A2/pt not_active Application Discontinuation
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- 2011-05-05 WO PCT/US2011/035354 patent/WO2011140337A2/en active Application Filing
- 2011-05-05 MX MX2012012859A patent/MX2012012859A/es unknown
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- 2011-05-05 CA CA2798355A patent/CA2798355C/en active Active
- 2011-05-05 EP EP16187485.4A patent/EP3121191B1/en not_active Not-in-force
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2012
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2015
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2016
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2017
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2018
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2021
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2023
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