DK3430072T3 - Fremgangsmåde til oprensning af poloxamerer - Google Patents

Fremgangsmåde til oprensning af poloxamerer Download PDF

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Publication number
DK3430072T3
DK3430072T3 DK17705555.5T DK17705555T DK3430072T3 DK 3430072 T3 DK3430072 T3 DK 3430072T3 DK 17705555 T DK17705555 T DK 17705555T DK 3430072 T3 DK3430072 T3 DK 3430072T3
Authority
DK
Denmark
Prior art keywords
poloxamerer
cleaning
cleaning poloxamerer
Prior art date
Application number
DK17705555.5T
Other languages
Danish (da)
English (en)
Inventor
Anja Licht
Almut Rapp
Hagen Joerg Von
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Application granted granted Critical
Publication of DK3430072T3 publication Critical patent/DK3430072T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/30Post-polymerisation treatment, e.g. recovery, purification, drying
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/02Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
    • B01J20/20Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising free carbon; comprising carbon obtained by carbonising processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28004Sorbent size or size distribution, e.g. particle size
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28016Particle form
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2650/00Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G2650/28Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type
    • C08G2650/58Ethylene oxide or propylene oxide copolymers, e.g. pluronics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/50Soluble polymers, e.g. polyethyleneglycol [PEG]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Inorganic Chemistry (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polyethers (AREA)
DK17705555.5T 2016-03-17 2017-02-20 Fremgangsmåde til oprensning af poloxamerer DK3430072T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16160811 2016-03-17
PCT/EP2017/000238 WO2017157505A1 (en) 2016-03-17 2017-02-20 Method for purifying poloxamers

Publications (1)

Publication Number Publication Date
DK3430072T3 true DK3430072T3 (da) 2020-08-31

Family

ID=55588093

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17705555.5T DK3430072T3 (da) 2016-03-17 2017-02-20 Fremgangsmåde til oprensning af poloxamerer

Country Status (7)

Country Link
US (1) US11180610B2 (de)
EP (1) EP3430072B1 (de)
JP (1) JP7037495B2 (de)
KR (1) KR20180125999A (de)
CN (1) CN108779242B (de)
DK (1) DK3430072T3 (de)
WO (1) WO2017157505A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111542596A (zh) * 2017-11-01 2020-08-14 朱诺治疗学股份有限公司 产生工程化细胞的治疗性组合物的方法
US11891510B2 (en) 2017-12-21 2024-02-06 Sigma-Aldrich Co. Llc Poloxamer compositions and methods of making and using same
WO2020218584A1 (ja) * 2019-04-26 2020-10-29 味の素株式会社 細胞培養用組成物
WO2023100975A1 (ja) 2021-12-01 2023-06-08 中外製薬株式会社 抗体含有製剤の調製方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3740421A (en) 1966-09-19 1973-06-19 Basf Wyandotte Corp Polyoxyethylene-polyoxypropylene aqueous gels
US3579465A (en) 1967-10-16 1971-05-18 Wyandotte Chemicals Corp Aqueous gels of polyoxyethylated polyoxypropylene glycol adducts of ethylene diamine
CA1268481A (en) 1984-11-13 1990-05-01 Atsushi Aoshima Process for purification of polyether
JPS61120831A (ja) * 1984-11-16 1986-06-07 Asahi Chem Ind Co Ltd 粗ポリアルキレングリコ−ルの精製法
US5350714A (en) * 1993-11-08 1994-09-27 Shipley Company Inc. Point-of-use purification
JP3777123B2 (ja) 2000-04-28 2006-05-24 ブリュッヒャー ゲゼルシャフト ミット ベシュレンクテル ハフツング 球状活性炭を製造する方法
US6761824B2 (en) 2000-08-17 2004-07-13 Reeve Lorraine E Process for the fractionation of polymers
DE20221998U1 (de) 2002-11-20 2010-05-12 BLüCHER GMBH Kugelaktivkohle
CN1929850B (zh) 2003-09-05 2010-05-12 艾维动物健康公司 精制的聚氧丙烯/聚氧乙烯共聚物及其制备方法
KR101343040B1 (ko) 2010-12-28 2013-12-18 주식회사 삼양바이오팜 정제된 폴록사머 및 그의 정제방법
WO2013028330A2 (en) * 2011-08-19 2013-02-28 Emd Millipore Corporation Methods of reducing level of one of more impurities in a sample during protein purification
RU2014138474A (ru) 2012-02-24 2016-04-10 СтемСентРкс, Инк. Новые модуляторы и способы применения
AR093460A1 (es) * 2012-11-14 2015-06-10 Merck Patent Ges Mit Beschränkter Haftung Medios de cultivo celular
EP3003325A4 (de) 2013-05-29 2017-01-11 Biogen MA Inc. Verfahren zur bewertung von zellkultur-zusatzstoffen
EP3019594B1 (de) 2013-07-11 2020-12-02 Merck Patent GmbH Zellkulturmedien
ES2778680T3 (es) 2014-03-25 2020-08-11 Hoffmann La Roche Procedimientos de preparación de un poloxámero para su uso en medio de cultivo celular

Also Published As

Publication number Publication date
EP3430072A1 (de) 2019-01-23
CN108779242B (zh) 2021-06-11
WO2017157505A1 (en) 2017-09-21
CN108779242A (zh) 2018-11-09
EP3430072B1 (de) 2020-07-01
KR20180125999A (ko) 2018-11-26
JP7037495B2 (ja) 2022-03-16
JP2019511606A (ja) 2019-04-25
US11180610B2 (en) 2021-11-23
US20190085125A1 (en) 2019-03-21

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