DK3427726T3 - Ark med vedvarende lægemiddelfrigvelse til behandling af nerveskade - Google Patents

Ark med vedvarende lægemiddelfrigvelse til behandling af nerveskade Download PDF

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Publication number
DK3427726T3
DK3427726T3 DK17763162.9T DK17763162T DK3427726T3 DK 3427726 T3 DK3427726 T3 DK 3427726T3 DK 17763162 T DK17763162 T DK 17763162T DK 3427726 T3 DK3427726 T3 DK 3427726T3
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DK
Denmark
Prior art keywords
treatment
drug release
nerve injury
release sheets
sustained drug
Prior art date
Application number
DK17763162.9T
Other languages
English (en)
Inventor
Hiroyuki Tanaka
Kiyoshi Okada
Hideki Yoshikawa
Mitsuhiro Ebara
Kouji Suzuki
Original Assignee
Univ Osaka
Nat Inst Materials Science
Nippon Zoki Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Osaka, Nat Inst Materials Science, Nippon Zoki Pharmaceutical Co filed Critical Univ Osaka
Application granted granted Critical
Publication of DK3427726T3 publication Critical patent/DK3427726T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135Compounds containing heavy metals
    • A61K31/714Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/185Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Psychology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Dermatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK17763162.9T 2016-03-07 2017-03-06 Ark med vedvarende lægemiddelfrigvelse til behandling af nerveskade DK3427726T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2016043873 2016-03-07
JP2017008913 2017-01-20
JP2017037270 2017-02-28
PCT/JP2017/008730 WO2017154822A1 (ja) 2016-03-07 2017-03-06 神経損傷治療用薬剤徐放シート

Publications (1)

Publication Number Publication Date
DK3427726T3 true DK3427726T3 (da) 2023-05-15

Family

ID=59789448

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17763162.9T DK3427726T3 (da) 2016-03-07 2017-03-06 Ark med vedvarende lægemiddelfrigvelse til behandling af nerveskade

Country Status (15)

Country Link
US (2) US11324704B2 (da)
EP (1) EP3427726B1 (da)
JP (2) JP6750820B2 (da)
KR (1) KR102323065B1 (da)
CN (2) CN116473948A (da)
AU (1) AU2017230387B9 (da)
CA (1) CA3016391C (da)
DK (1) DK3427726T3 (da)
ES (1) ES2946262T3 (da)
IL (1) IL261533B (da)
PL (1) PL3427726T3 (da)
SG (1) SG11201806797UA (da)
TW (1) TWI790202B (da)
WO (1) WO2017154822A1 (da)
ZA (1) ZA201805801B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108738345A (zh) 2016-02-24 2018-11-02 国立大学法人大阪大学 试验方法
WO2018056412A1 (ja) * 2016-09-23 2018-03-29 国立大学法人大阪大学 シュワン細胞分化促進剤及び末梢神経再生促進剤
JP6650650B2 (ja) 2017-12-21 2020-02-19 国立大学法人大阪大学 神経系疾患治療剤
JP7391306B2 (ja) * 2018-07-09 2023-12-05 国立研究開発法人物質・材料研究機構 不織布、不織布の製造方法、及び、電界紡糸用組成物
JP2022517272A (ja) * 2019-01-15 2022-03-07 ユニバーシティ オブ ユタ リサーチ ファウンデーション 薬物を送達する神経ラップ
KR102245629B1 (ko) * 2019-04-10 2021-04-30 주식회사 제네웰 히알루론산계 녹는 필름, 이의 제조방법 및 이에 사용되는 이형지
AU2021208828A1 (en) * 2020-01-14 2022-07-28 Nippon Zoki Pharmaceutical Co., Ltd. Medical sheet
GB202000714D0 (en) 2020-01-17 2020-03-04 Ucl Business Biomaterials

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US6110472A (en) * 1992-12-10 2000-08-29 Hemogen Inc. Vitamin B12 containing scalp and skin treatment compositions
JPH07241433A (ja) * 1994-03-02 1995-09-19 Chiyoda Corp 悪臭気ガスの生物処理方法及びその装置
WO1998011900A2 (en) * 1996-09-18 1998-03-26 Sarill William J Compositions containing cobalamin and amino acids
US20120220962A1 (en) * 1999-12-16 2012-08-30 Technology Recovery Systems, Llc Transdermal and topical administration of vitamins using basic permeation enhancers
US6685956B2 (en) 2001-05-16 2004-02-03 The Research Foundation At State University Of New York Biodegradable and/or bioabsorbable fibrous articles and methods for using the articles for medical applications
GB0210517D0 (en) 2002-05-03 2002-06-19 Giltech Ltd Material
JP2005220070A (ja) * 2004-02-05 2005-08-18 Medgel Corp 神経再生および保護のための生体吸収性高分子ハイドロゲル製剤
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JP2007236551A (ja) * 2006-03-07 2007-09-20 National Institute For Materials Science キチン誘導体複合材料及び医療用材料
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JP2011530661A (ja) * 2008-08-08 2011-12-22 ビーエーエスエフ ソシエタス・ヨーロピア 活性成分の制御放出を伴う有効成分含有繊維表面構造体、その使用、およびその生産のための方法
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WO2011162317A1 (ja) * 2010-06-25 2011-12-29 日本臓器製薬株式会社 被検物質の判定又は評価方法
CN102525689B (zh) * 2010-12-20 2015-06-24 上海市第六人民医院 取向纳米纤维仿生神经导管及其制作方法
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Also Published As

Publication number Publication date
KR102323065B1 (ko) 2021-11-08
EP3427726A4 (en) 2019-10-09
AU2017230387B9 (en) 2022-08-04
US20190083415A1 (en) 2019-03-21
TWI790202B (zh) 2023-01-21
JPWO2017154822A1 (ja) 2019-04-18
CA3016391A1 (en) 2017-09-14
AU2017230387A1 (en) 2018-10-04
WO2017154822A1 (ja) 2017-09-14
ES2946262T3 (es) 2023-07-14
CA3016391C (en) 2024-06-04
US12016959B2 (en) 2024-06-25
EP3427726B1 (en) 2023-05-03
JP7057573B2 (ja) 2022-04-20
CN108883077A (zh) 2018-11-23
EP3427726A1 (en) 2019-01-16
KR20180120219A (ko) 2018-11-05
ZA201805801B (en) 2019-05-29
IL261533A (en) 2018-10-31
US20210205234A1 (en) 2021-07-08
CN116473948A (zh) 2023-07-25
PL3427726T3 (pl) 2023-07-10
JP6750820B2 (ja) 2020-09-02
TW201737901A (zh) 2017-11-01
IL261533B (en) 2021-12-01
SG11201806797UA (en) 2018-09-27
AU2017230387B2 (en) 2022-07-21
US11324704B2 (en) 2022-05-10
JP2020169201A (ja) 2020-10-15

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