DK3331853T3 - Udvalgt amid af -hydroxybutansyre og anvendelser deraf i behandlingen af alkoholmisbrug - Google Patents

Udvalgt amid af -hydroxybutansyre og anvendelser deraf i behandlingen af alkoholmisbrug Download PDF

Info

Publication number
DK3331853T3
DK3331853T3 DK16791313.6T DK16791313T DK3331853T3 DK 3331853 T3 DK3331853 T3 DK 3331853T3 DK 16791313 T DK16791313 T DK 16791313T DK 3331853 T3 DK3331853 T3 DK 3331853T3
Authority
DK
Denmark
Prior art keywords
treatment
alcohol abuse
hydroxybutanoic acid
selected amide
amide
Prior art date
Application number
DK16791313.6T
Other languages
Danish (da)
English (en)
Inventor
Roberto Cacciaglia
Antonella Loche
Original Assignee
Laboratorio Farm C T S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorio Farm C T S R L filed Critical Laboratorio Farm C T S R L
Application granted granted Critical
Publication of DK3331853T3 publication Critical patent/DK3331853T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK16791313.6T 2015-08-04 2016-08-03 Udvalgt amid af -hydroxybutansyre og anvendelser deraf i behandlingen af alkoholmisbrug DK3331853T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITUB2015A002860A ITUB20152860A1 (it) 2015-08-04 2015-08-04 Selezionata amide dell?acido ?-idrossibutirrico e suoi usi nel trattamento dell?abuso da alcool
PCT/EP2016/068517 WO2017021438A1 (en) 2015-08-04 2016-08-03 SELECTED AMIDE OF γ -HYDROXYBUTYRIC ACID AND USES THEREOF IN THE TREATMENT OF ALCOHOL MISUSE

Publications (1)

Publication Number Publication Date
DK3331853T3 true DK3331853T3 (da) 2020-03-16

Family

ID=54542363

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16791313.6T DK3331853T3 (da) 2015-08-04 2016-08-03 Udvalgt amid af -hydroxybutansyre og anvendelser deraf i behandlingen af alkoholmisbrug

Country Status (24)

Country Link
US (1) US10336687B2 (enExample)
EP (1) EP3331853B1 (enExample)
JP (1) JP6832336B2 (enExample)
KR (1) KR102817897B1 (enExample)
CN (1) CN108026029B (enExample)
AU (1) AU2016302869B2 (enExample)
CA (1) CA2994599C (enExample)
CL (1) CL2018000282A1 (enExample)
CO (1) CO2018002428A2 (enExample)
DK (1) DK3331853T3 (enExample)
EA (1) EA033769B9 (enExample)
ES (1) ES2776628T3 (enExample)
GE (1) GEP20207107B (enExample)
IL (1) IL257314B (enExample)
IT (1) ITUB20152860A1 (enExample)
MX (1) MX2018001239A (enExample)
MY (1) MY185942A (enExample)
PH (1) PH12018550008A1 (enExample)
PL (1) PL3331853T3 (enExample)
PT (1) PT3331853T (enExample)
SM (1) SMT202000337T1 (enExample)
UA (1) UA121994C2 (enExample)
WO (1) WO2017021438A1 (enExample)
ZA (1) ZA201801402B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018310882C1 (en) 2017-07-31 2021-12-09 Novartis Ag Use of mavoglurant in the reduction of alcohol use or in preventing relapse into alcohol use
KR20200035035A (ko) 2017-07-31 2020-04-01 노파르티스 아게 코카인 사용 감소 또는 코카인 사용 재발 예방에 있어서 마보글루란트의 용도
CN113185403A (zh) * 2021-07-02 2021-07-30 山东国邦药业有限公司 一种甲醚制备环丙胺中间体环丙甲酸甲酯的方法
WO2023126076A1 (en) * 2022-01-03 2023-07-06 Laboratorio Farmaceutico C.T. S.R.L. Medical use of an amide of y-hydroxybutyric acid in the treatment of fragile x syndrome

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1283782B1 (it) * 1996-08-09 1998-04-30 Ct Lab Farm Srl Uso di ammidi dell'acido gamma-idrossibutirrico nel trattamento di tossicodipendenze,ed in particolare sell'alcolismo

Also Published As

Publication number Publication date
BR112018002245A2 (pt) 2018-09-18
KR102817897B1 (ko) 2025-06-05
JP2018523644A (ja) 2018-08-23
KR20180066033A (ko) 2018-06-18
CA2994599A1 (en) 2017-02-09
GEAP202014717A (en) 2020-01-27
CN108026029A (zh) 2018-05-11
AU2016302869A1 (en) 2018-03-15
ZA201801402B (en) 2019-01-30
CA2994599C (en) 2023-08-29
EA033769B1 (ru) 2019-11-22
US20180230086A1 (en) 2018-08-16
IL257314A (en) 2018-03-29
JP6832336B2 (ja) 2021-02-24
CO2018002428A2 (es) 2018-07-10
US10336687B2 (en) 2019-07-02
PT3331853T (pt) 2020-02-25
CL2018000282A1 (es) 2018-07-13
ES2776628T3 (es) 2020-07-31
AU2016302869B2 (en) 2020-10-22
EP3331853A1 (en) 2018-06-13
MX2018001239A (es) 2018-07-06
GEP20207107B (en) 2020-05-11
WO2017021438A1 (en) 2017-02-09
MY185942A (en) 2021-06-14
CN108026029B (zh) 2020-12-04
EP3331853B1 (en) 2019-12-11
ITUB20152860A1 (it) 2017-02-04
SMT202000337T1 (it) 2020-07-08
UA121994C2 (uk) 2020-08-25
IL257314B (en) 2020-04-30
EA033769B9 (ru) 2020-04-10
EA201890419A1 (ru) 2018-07-31
PH12018550008A1 (en) 2018-07-09
PL3331853T3 (pl) 2020-06-15

Similar Documents

Publication Publication Date Title
DK3678668T3 (da) ENPP1-inhibitorer og deres anvendelse til behandling af kræft
IL257105A (en) Modified cells and methods of therapy
DK3334422T3 (da) Anvendelse af cannabidiolsyre i behandling af epilepsi
DK3842429T3 (da) Heterocykliske inhibitorer af ERK1 og ERK2 og anvendelse deraf i behandling af cancer
SI3328419T1 (sl) PD-1-vezavne molekule in postopki uporabe le-teh
EP3359171C0 (en) Use of akkermansia muciniphila for treating inflammatory conditions
DK3096798T3 (da) Plasmakallikreinbindende proteiner og anvendelser deraf til behandling af hereditært angioødem
DK3102673T3 (da) Fremgangsmåder og sammensætninger til behandling af beta-talassæmi
DK3256218T3 (da) Kdm1a-hæmmer og anvendelse deraf i terapi
DK3242947T3 (da) Genterapi og elektroporese til behandling af maligniteter
PL3277270T3 (pl) Kompozycje i sposoby leczenia niedokrwistości
DK3007695T3 (da) Sammensætninger og fremgangsmåder til behandling af anæmi
DK3197472T3 (da) Rekombinante phe-frie proteiner til anvendelse i behandlingen af phenylketonuri
DK2994157T3 (da) Tafa4-forbindelser og anvendelser deraf til behandling af smerte
DK3307296T3 (da) Timp2 til anvendelse til behandling af aldringsassocierede tilstande
DK3395354T3 (da) Plasminogen til anvendelse i behandling af diabetisk nefropati
DK3303339T3 (da) Pde9-inhibitorer med imidazotriazinonskelet og imidazopyrazinonskelet til behandling af perifere sygdomme
EP3426244C0 (en) 3-phosphoglycerate dehydrogenase inhibitors and uses thereof
LT3717646T (lt) Angelmano sindromo gydymas priešprasme nukleorūgštimi
DK3391902T5 (da) Plasminogen til anvendelse i behandlingen af diabetisk angiokardiopati
DK3710000T3 (da) Tradipitant til anvendelse til behandling af gastroparese
DK3236960T3 (da) Fluralaner til anvendelse i behandling af demodicose
DK3374497T3 (da) Modificerede makrofager til anvendelse i behandlingen af kræft
DK3426243T3 (da) 3-phosphoglyceratdehydrogenase-inhibitorer og anvendelser deraf
DK3532059T3 (da) Kombinationsterapi med bromdomæne- og ekstraterminal proteinhæmmer