CO2018002428A2 - Amida seleccionada de ácido gamma-hidroxiburico y usos de la misma en el tratamiento de abuso de alcohol - Google Patents

Amida seleccionada de ácido gamma-hidroxiburico y usos de la misma en el tratamiento de abuso de alcohol

Info

Publication number
CO2018002428A2
CO2018002428A2 CONC2018/0002428A CO2018002428A CO2018002428A2 CO 2018002428 A2 CO2018002428 A2 CO 2018002428A2 CO 2018002428 A CO2018002428 A CO 2018002428A CO 2018002428 A2 CO2018002428 A2 CO 2018002428A2
Authority
CO
Colombia
Prior art keywords
treatment
alcohol abuse
hydroxyiburic
gamma
acid
Prior art date
Application number
CONC2018/0002428A
Other languages
English (en)
Spanish (es)
Inventor
Roberto Cacciaglia
Antonella Loche
Original Assignee
Laboratorio Farm C T S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorio Farm C T S R L filed Critical Laboratorio Farm C T S R L
Publication of CO2018002428A2 publication Critical patent/CO2018002428A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CONC2018/0002428A 2015-08-04 2018-03-02 Amida seleccionada de ácido gamma-hidroxiburico y usos de la misma en el tratamiento de abuso de alcohol CO2018002428A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITUB2015A002860A ITUB20152860A1 (it) 2015-08-04 2015-08-04 Selezionata amide dell?acido ?-idrossibutirrico e suoi usi nel trattamento dell?abuso da alcool
PCT/EP2016/068517 WO2017021438A1 (en) 2015-08-04 2016-08-03 SELECTED AMIDE OF γ -HYDROXYBUTYRIC ACID AND USES THEREOF IN THE TREATMENT OF ALCOHOL MISUSE

Publications (1)

Publication Number Publication Date
CO2018002428A2 true CO2018002428A2 (es) 2018-07-10

Family

ID=54542363

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2018/0002428A CO2018002428A2 (es) 2015-08-04 2018-03-02 Amida seleccionada de ácido gamma-hidroxiburico y usos de la misma en el tratamiento de abuso de alcohol

Country Status (24)

Country Link
US (1) US10336687B2 (enExample)
EP (1) EP3331853B1 (enExample)
JP (1) JP6832336B2 (enExample)
KR (1) KR102817897B1 (enExample)
CN (1) CN108026029B (enExample)
AU (1) AU2016302869B2 (enExample)
CA (1) CA2994599C (enExample)
CL (1) CL2018000282A1 (enExample)
CO (1) CO2018002428A2 (enExample)
DK (1) DK3331853T3 (enExample)
EA (1) EA033769B9 (enExample)
ES (1) ES2776628T3 (enExample)
GE (1) GEP20207107B (enExample)
IL (1) IL257314B (enExample)
IT (1) ITUB20152860A1 (enExample)
MX (1) MX2018001239A (enExample)
MY (1) MY185942A (enExample)
PH (1) PH12018550008A1 (enExample)
PL (1) PL3331853T3 (enExample)
PT (1) PT3331853T (enExample)
SM (1) SMT202000337T1 (enExample)
UA (1) UA121994C2 (enExample)
WO (1) WO2017021438A1 (enExample)
ZA (1) ZA201801402B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018310882C1 (en) 2017-07-31 2021-12-09 Novartis Ag Use of mavoglurant in the reduction of alcohol use or in preventing relapse into alcohol use
KR20200035035A (ko) 2017-07-31 2020-04-01 노파르티스 아게 코카인 사용 감소 또는 코카인 사용 재발 예방에 있어서 마보글루란트의 용도
CN113185403A (zh) * 2021-07-02 2021-07-30 山东国邦药业有限公司 一种甲醚制备环丙胺中间体环丙甲酸甲酯的方法
WO2023126076A1 (en) * 2022-01-03 2023-07-06 Laboratorio Farmaceutico C.T. S.R.L. Medical use of an amide of y-hydroxybutyric acid in the treatment of fragile x syndrome

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1283782B1 (it) * 1996-08-09 1998-04-30 Ct Lab Farm Srl Uso di ammidi dell'acido gamma-idrossibutirrico nel trattamento di tossicodipendenze,ed in particolare sell'alcolismo

Also Published As

Publication number Publication date
BR112018002245A2 (pt) 2018-09-18
KR102817897B1 (ko) 2025-06-05
JP2018523644A (ja) 2018-08-23
KR20180066033A (ko) 2018-06-18
CA2994599A1 (en) 2017-02-09
GEAP202014717A (en) 2020-01-27
CN108026029A (zh) 2018-05-11
AU2016302869A1 (en) 2018-03-15
ZA201801402B (en) 2019-01-30
CA2994599C (en) 2023-08-29
EA033769B1 (ru) 2019-11-22
US20180230086A1 (en) 2018-08-16
IL257314A (en) 2018-03-29
JP6832336B2 (ja) 2021-02-24
US10336687B2 (en) 2019-07-02
PT3331853T (pt) 2020-02-25
CL2018000282A1 (es) 2018-07-13
ES2776628T3 (es) 2020-07-31
AU2016302869B2 (en) 2020-10-22
EP3331853A1 (en) 2018-06-13
MX2018001239A (es) 2018-07-06
GEP20207107B (en) 2020-05-11
WO2017021438A1 (en) 2017-02-09
MY185942A (en) 2021-06-14
CN108026029B (zh) 2020-12-04
DK3331853T3 (da) 2020-03-16
EP3331853B1 (en) 2019-12-11
ITUB20152860A1 (it) 2017-02-04
SMT202000337T1 (it) 2020-07-08
UA121994C2 (uk) 2020-08-25
IL257314B (en) 2020-04-30
EA033769B9 (ru) 2020-04-10
EA201890419A1 (ru) 2018-07-31
PH12018550008A1 (en) 2018-07-09
PL3331853T3 (pl) 2020-06-15

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