DK333083A - 2-aza-bicyclo(2.2.2)octan-3-carboxylsyrederivater, deres fremstilling og anvendelse samt ved fremstillingen anvendelige mellemprodukter og disses fremstilling - Google Patents

2-aza-bicyclo(2.2.2)octan-3-carboxylsyrederivater, deres fremstilling og anvendelse samt ved fremstillingen anvendelige mellemprodukter og disses fremstilling Download PDF

Info

Publication number
DK333083A
DK333083A DK333083A DK333083A DK333083A DK 333083 A DK333083 A DK 333083A DK 333083 A DK333083 A DK 333083A DK 333083 A DK333083 A DK 333083A DK 333083 A DK333083 A DK 333083A
Authority
DK
Denmark
Prior art keywords
preparation
octan
aza
bicyclo
carboxylic acid
Prior art date
Application number
DK333083A
Other languages
Danish (da)
English (en)
Other versions
DK333083D0 (da
Inventor
Rainer Henning
Hansjoerg Urbach
Reinhard Becker
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK333083D0 publication Critical patent/DK333083D0/da
Publication of DK333083A publication Critical patent/DK333083A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK333083A 1982-07-20 1983-07-19 2-aza-bicyclo(2.2.2)octan-3-carboxylsyrederivater, deres fremstilling og anvendelse samt ved fremstillingen anvendelige mellemprodukter og disses fremstilling DK333083A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823227055 DE3227055A1 (de) 1982-07-20 1982-07-20 Neue derivate der 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure als zwischenstufe und verfahren zu deren herstellung

Publications (2)

Publication Number Publication Date
DK333083D0 DK333083D0 (da) 1983-07-19
DK333083A true DK333083A (da) 1984-01-21

Family

ID=6168834

Family Applications (1)

Application Number Title Priority Date Filing Date
DK333083A DK333083A (da) 1982-07-20 1983-07-19 2-aza-bicyclo(2.2.2)octan-3-carboxylsyrederivater, deres fremstilling og anvendelse samt ved fremstillingen anvendelige mellemprodukter og disses fremstilling

Country Status (13)

Country Link
EP (1) EP0105102A1 (es)
JP (1) JPS5929686A (es)
KR (1) KR840005429A (es)
AU (1) AU1699383A (es)
DE (1) DE3227055A1 (es)
DK (1) DK333083A (es)
ES (2) ES8404351A1 (es)
FI (1) FI832602A (es)
GR (1) GR78901B (es)
IL (1) IL69271A0 (es)
NO (1) NO832648L (es)
PT (1) PT77058B (es)
ZA (1) ZA835237B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3303344A1 (de) 1983-02-02 1984-08-02 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von n-alkylierten aminosaeuren und deren estern
DE3410732A1 (de) * 1984-03-23 1985-09-26 Hoechst Ag, 6230 Frankfurt Methode zur behandlung des glaukoms
US5684016A (en) * 1984-04-12 1997-11-04 Hoechst Aktiengesellschaft Method of treating cardiac insufficiency
FR2619813B1 (fr) * 1987-08-28 1991-05-03 Adir Nouveaux derives de l'acide aza - 2 bicyclooctane carboxylique - 3, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
WO1990002123A1 (en) * 1988-08-23 1990-03-08 Pfizer Inc. Amino-substituted bridged azabicyclic quinolone carboxylic acids and esters
FR2635684A1 (fr) * 1988-08-24 1990-03-02 Adir Utilisation de derives de l'acide aza - 2 bicyclooctane (2.2.2) carboxylique - 3 pour l'obtention de medicaments destines au traitement des maladies consecutives a l'alteration de la paroi vasculaire ainsi qu'aux troubles de la microcirculation
IE63490B1 (en) * 1988-11-24 1995-05-03 Hoechst Ag Peptides having bradykinin antagonist action
FR2655989B1 (fr) * 1989-12-20 1992-02-28 Adir Nouveaux derives d'amino-acides substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2746394B1 (fr) 1996-03-20 1998-05-29 Roussel Uclaf Nouveaux composes tricycliques, leur procede de preparation, et les intermediaires de ce procede, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
PT796855E (pt) 1996-03-20 2002-07-31 Hoechst Ag Inibicao da reabsorcao nos ossos e antagonistas de vitronectina
DE19653647A1 (de) 1996-12-20 1998-06-25 Hoechst Ag Vitronectin - Rezeptorantagonisten, deren Herstellung sowie deren Verwendung
DE19741235A1 (de) 1997-09-18 1999-03-25 Hoechst Marion Roussel De Gmbh Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19741873A1 (de) * 1997-09-23 1999-03-25 Hoechst Marion Roussel De Gmbh Neue 5-Ring-Heterocyclen, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19751251A1 (de) 1997-11-19 1999-05-20 Hoechst Marion Roussel De Gmbh Substituierte Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmezeutische Präparate
DE19821483A1 (de) 1998-05-14 1999-11-18 Hoechst Marion Roussel De Gmbh Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
SE0000382D0 (sv) 2000-02-07 2000-02-07 Astrazeneca Ab New process
US20030114420A1 (en) * 2000-06-28 2003-06-19 Salvati Mark E. Fused cyclic modulators of nuclear hormone receptor function
AU8821301A (en) * 2000-06-28 2002-01-08 Bristol Myers Squibb Co Selective androgen receptor modulators and methods for their identification, design and use
US6953679B2 (en) 2000-09-19 2005-10-11 Bristol-Myers Squibb Company Method for the preparation of fused heterocyclic succinimide compounds and analogs thereof
EP1854798A3 (en) 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3177311D1 (de) * 1980-08-30 1994-06-09 Hoechst Ag Aminosäurederivate, Verfahren zu ihrer Herstellung, diese enthaltende Mittel und deren Verwendung.
FR2492381A1 (fr) * 1980-10-21 1982-04-23 Science Union & Cie Nouveaux acides aza bicyclo alcane carboxyliques substitues leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme

Also Published As

Publication number Publication date
ZA835237B (en) 1984-03-28
ES524215A0 (es) 1984-05-01
ES524214A0 (es) 1984-05-01
DK333083D0 (da) 1983-07-19
GR78901B (es) 1984-10-02
JPS5929686A (ja) 1984-02-16
AU1699383A (en) 1984-01-26
FI832602A0 (fi) 1983-07-18
KR840005429A (ko) 1984-11-12
PT77058B (de) 1986-02-26
DE3227055A1 (de) 1984-01-26
FI832602A (fi) 1984-01-21
ES8404352A1 (es) 1984-05-01
NO832648L (no) 1984-01-23
EP0105102A1 (de) 1984-04-11
PT77058A (de) 1983-08-01
ES8404351A1 (es) 1984-05-01
IL69271A0 (en) 1983-11-30

Similar Documents

Publication Publication Date Title
DK333083A (da) 2-aza-bicyclo(2.2.2)octan-3-carboxylsyrederivater, deres fremstilling og anvendelse samt ved fremstillingen anvendelige mellemprodukter og disses fremstilling
DK504485D0 (da) Substituerede azolylmethyl-cyclopropyl-carbinol-derivater, deres fremstilling og anvendelse samt ved fremstillingen anvendelige mellemprodukter og fremstilling deraf
DK425583A (da) Fremgangsmaade til fremstilling af 4'-demethyl-epipodophyllotoxin-beta-d-ethylidenglycocid og acylderivater deraf samt mellemprodukt til brug ved fremgangsmaaden
NO852124L (no) Fremgangsmaate ved fremstilling av kinolonderivater.
NO852994L (no) Fremgangsmaate ved fremstilling av glutaramidderivater.
DK140382A (da) Tetrahydrophthalimider og deres anvendelse,samt fremgangsmaadetil fremstilling deraf
NO167747C (no) Fremgangsmaate for fremstilling av tetra-n-acetyl-kitotetraose, penta-n-acetyl-kitopentaose og heksa-n-acetyl-kitoheksaose ved delvis hydrolyse av kitin.
DK198387A (da) 1-hydroxy-2-pyridoner, deres fremstilling og anvendelse samt ved fremgangsmaaden anvendelige mellemprodukter og disses fremstilling
NO170071C (no) Fremgangsmaate ved fremstilling av klordioksyd.
NO165755C (no) Fremgangsmaate ved fremstilling av tetrafluorbenzosyre.
NO884665D0 (no) Fremgangsmaate ved fremstilling av 9-oh-alkoksyguanin.
NO166326C (no) Fremgangsmaate ved fremstilling av terapeutisk aktive 3,7-substituerte-8-oxo-5-thia-1-azabicyclo-(4,2,0)oct-2-en-2-carboxylater.
DK504680A (da) 4,5-umaettede 16-hydroxyprostansyrederivater og deres fremstilling samt mellemprodukter hertil og disses fremstilling
NO165676C (no) Fremgangsmaate ved fremstilling av pyrrolidonderivater.
NO852810L (no) Fremgangsmaate ved fremstilling av fluorallylaminderivater.
IT8521570A0 (it) Procedimento di preparazione di microlattici invertiti ed i microlattici invertiti ottenuti.
DK326085A (da) 4-amino-2-phenylquinoliner, deres fremstilling og anvendelse samt ved fremstillingen anvendelige mellemprodukter
NO166931C (no) Fremgangsmaate ved fremstilling av klordioksyd.
DK184679A (da) Substituerede 1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepiner fremgangsmaade til deres fremstilling samt deres anvendelse
NO854655L (no) Fremgangsmaate ved fremstilling av flavolignanderivateer.
DK687787D0 (da) Carbamoyloxylabdaner, deres fremstilling og anvendelse samt ved fremstillingen anvendelige mellemprodukter
NO860273L (no) Fremgangsmaate for fremstilling av 4,4-dialkyl-2-azetidinoner.
DK247884A (da) Substituerede tetrahydrothiopyran-3,5-dion-4-carboxamider, fremgangsmaade til deres fremstilling og deres anvendelse samt mellemprodukter til fremstillingen
DK111481A (da) 1,4,3,6-dianhydro-2,5-diazido-2,5-didesoxy-hexitoler deres fremstilling og anvendelse samt mellemprodukter til fremstillingen
DK548487A (da) Substituerede aminoketaler, deres fremstilling og anvendelse samt ved fremgangsmaaden anvendelige dioxalaner og disses fremstilling

Legal Events

Date Code Title Description
ATS Application withdrawn