DK3277827T3 - Svampeceller og fremgangsmåder til fremstilling af produkter afledt af meget langkædede fedtsyrer - Google Patents

Svampeceller og fremgangsmåder til fremstilling af produkter afledt af meget langkædede fedtsyrer Download PDF

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Publication number
DK3277827T3
DK3277827T3 DK16717489.5T DK16717489T DK3277827T3 DK 3277827 T3 DK3277827 T3 DK 3277827T3 DK 16717489 T DK16717489 T DK 16717489T DK 3277827 T3 DK3277827 T3 DK 3277827T3
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Denmark
Prior art keywords
methods
fatty acids
products derived
manufacturing products
long chained
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DK16717489.5T
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English (en)
Inventor
Florian David
Verena Siewers
Anastasia Krivoruchko
Tao Yu
yong-jin Zhou
Jens Nielsen
Leonie Wenning
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Biopetrolia Ab
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Publication of DK3277827T3 publication Critical patent/DK3277827T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0008Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6463Glycerides obtained from glyceride producing microorganisms, e.g. single cell oil
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y102/00Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/0105Long-chain-fatty-acyl-CoA reductase (1.2.1.50)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01075Long-chain-alcohol O-fatty-acyltransferase (2.3.1.75)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK16717489.5T 2015-04-02 2016-04-01 Svampeceller og fremgangsmåder til fremstilling af produkter afledt af meget langkædede fedtsyrer DK3277827T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562142236P 2015-04-02 2015-04-02
PCT/SE2016/050274 WO2016159869A1 (en) 2015-04-02 2016-04-01 Fungal cells and methods for production of very long chain fatty acid derived products

Publications (1)

Publication Number Publication Date
DK3277827T3 true DK3277827T3 (da) 2021-06-14

Family

ID=55795160

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16717489.5T DK3277827T3 (da) 2015-04-02 2016-04-01 Svampeceller og fremgangsmåder til fremstilling af produkter afledt af meget langkædede fedtsyrer

Country Status (5)

Country Link
US (1) US10550413B2 (da)
EP (1) EP3277827B1 (da)
CN (1) CN108271383B (da)
DK (1) DK3277827T3 (da)
WO (1) WO2016159869A1 (da)

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DE102014220186B4 (de) 2013-12-12 2017-06-22 Technische Universität Dresden Hefestämme und Verfahren zur Produktion von Omega-Hydroxyfettsäuren und Dicarbonsäuren
ES2864102T3 (es) 2015-11-18 2021-10-13 Provivi Inc Microorganismos para la producción de feromonas de insectos y compuestos relacionados
CN109890832B (zh) 2016-06-06 2022-08-12 普罗维维股份有限公司 脂肪醇和脂肪醛的半生物合成产生
US11034981B2 (en) 2017-02-07 2021-06-15 Temasek Life Sciences Laboratory Limited Production of fatty alcohols in Rhodosporidium
JP6934303B2 (ja) 2017-02-08 2021-09-15 花王株式会社 脂肪族アルコールの生産方法
MX2019009708A (es) 2017-02-17 2020-02-07 Hyasynth Biologicals Inc Metodo y linea celular para la produccion de fitocannabinoides y analogos de fitocannabinoides en levadura.
US10557152B2 (en) 2017-05-12 2020-02-11 The Regents Of The University Of California Yeast host cells and methods for producing fatty alcohols
US11104921B2 (en) 2017-05-17 2021-08-31 Provivi, Inc. Microorganisms for the production of insect pheromones and related compounds
CN110358692B (zh) * 2018-04-09 2021-07-27 中国科学院青岛生物能源与过程研究所 生产神经酸的重组酵母菌株及其应用
WO2020181091A1 (en) * 2019-03-05 2020-09-10 Bp Corporation North America Inc. Fatty acyl-acp reductases and their uses
US11692209B2 (en) * 2019-03-27 2023-07-04 Melt&Marble Ab Genetically modified fungal cells for overexpression of an acetyl-CoA carboxylase and a pyruvate carboxylase
CN110923261B (zh) * 2019-12-20 2021-12-17 江南大学 一种提高酿酒酵母细胞膜脂肪酸c20:0和/或c22:0含量的方法
CN111118052A (zh) * 2020-01-19 2020-05-08 天津大学 重组酿酒酵母菌及其构建方法以及生产羟基脂肪酸的应用
CN113774078B (zh) * 2020-06-09 2024-04-16 中国科学院大连化学物理研究所 一种重组巴斯德毕赤酵母菌株、其构建方法和应用
CN111979135A (zh) * 2020-09-02 2020-11-24 华东理工大学 一种解脂耶氏酵母基因工程菌及其应用
CN114517164A (zh) * 2020-11-19 2022-05-20 中国科学院青岛生物能源与过程研究所 一种脂肪酸延长酶基因在酵母合成神经酸中的应用
CN114369541A (zh) * 2020-11-23 2022-04-19 森瑞斯生物科技(深圳)有限公司 一种优化代谢流产大麻萜酚酸的重组酿酒酵母及其构建方法和应用
CN112941119B (zh) * 2021-01-22 2022-08-30 江南大学 一种提高酿酒酵母工程菌脂肪酸乙酯产量的方法
CN115386588B (zh) * 2021-05-19 2024-04-26 中国科学院分子植物科学卓越创新中心 一种酵母合成昆虫性信息素的方法
US20230242944A1 (en) * 2022-01-31 2023-08-03 Isca Technologies, Inc. Methods for production of diatraea saccharalis pheromone precursors
CN114736907B (zh) * 2022-04-14 2023-07-11 浙江大学 扶桑绵粉蚧的蜡质合成基因PsFAR及其应用
US20220243230A1 (en) * 2022-04-21 2022-08-04 Conagen Inc. Bioconversion of 4-coumaric acid to resveratrol
CN114891653B (zh) * 2022-05-17 2023-07-25 南京工业大学 一株高产神经酸的重组解脂耶氏酵母菌及其构建方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1294898B1 (en) 2000-06-08 2006-08-30 Miami University FATTY ACID ELONGASE 3-KETOACYL CoA SYNTHASE POLYPEPTIDES
CN101680009B (zh) * 2007-03-28 2017-02-22 Reg生命科学有限责任公司 提高脂肪酸衍生物的产量
US9157103B2 (en) 2010-12-23 2015-10-13 Shell Oil Company Gene disruptants producing fatty acyl-CoA derivatives
WO2015042306A1 (en) 2013-09-18 2015-03-26 The Governors Of The University Of Alberta Genetically engineered saccharomyces cerevisiae and yarrowia lipolytica and production of fatty alcohols

Also Published As

Publication number Publication date
EP3277827B1 (en) 2021-03-24
CN108271383A (zh) 2018-07-10
US20180112240A1 (en) 2018-04-26
US10550413B2 (en) 2020-02-04
WO2016159869A1 (en) 2016-10-06
EP3277827A1 (en) 2018-02-07
CN108271383B (zh) 2022-04-19

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