DK3265075T3 - COMBINATION TREATMENT OF MULTIPLE MYELOMA WITH RONEPARSTAT - Google Patents
COMBINATION TREATMENT OF MULTIPLE MYELOMA WITH RONEPARSTAT Download PDFInfo
- Publication number
- DK3265075T3 DK3265075T3 DK16709148.7T DK16709148T DK3265075T3 DK 3265075 T3 DK3265075 T3 DK 3265075T3 DK 16709148 T DK16709148 T DK 16709148T DK 3265075 T3 DK3265075 T3 DK 3265075T3
- Authority
- DK
- Denmark
- Prior art keywords
- melphalan
- use according
- roneparstat
- treatment
- multiple myeloma
- Prior art date
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Classifications
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
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- A—HUMAN NECESSITIES
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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- A61K31/69—Boron compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
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| US201562129221P | 2015-03-06 | 2015-03-06 | |
| US201562153899P | 2015-04-28 | 2015-04-28 | |
| PCT/IB2016/051196 WO2016142814A1 (en) | 2015-03-06 | 2016-03-03 | Roneparstat combined therapy of multiple myeloma |
Publications (1)
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| DK3265075T3 true DK3265075T3 (en) | 2019-04-08 |
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| DK16709148.7T DK3265075T3 (en) | 2015-03-06 | 2016-03-03 | COMBINATION TREATMENT OF MULTIPLE MYELOMA WITH RONEPARSTAT |
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| EP (2) | EP3265075B1 (enExample) |
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| CA (1) | CA2978040A1 (enExample) |
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| ES (1) | ES2715556T3 (enExample) |
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| MX (1) | MX2017011093A (enExample) |
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| PT (1) | PT3265075T (enExample) |
| WO (1) | WO2016142814A1 (enExample) |
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| GB8727157D0 (en) * | 1987-11-19 | 1987-12-23 | Wellcome Found | Pharmaceutical formulations |
| US7781416B2 (en) | 2000-01-25 | 2010-08-24 | Sigma-Tau Research Switzerland S.A. | Derivatives of partially desulphated glycosaminoglycans as heparanase inhibitors, endowed with antiangiogenic activity and devoid of anticoagulating effect |
| IT1316986B1 (it) | 2000-01-25 | 2003-05-26 | Sigma Tau Ind Farmaceuti | Derivati glicosamminoglicani parzialmente desolfatati nonanticoagulanti ad attivita' antiangiogenica. |
| CZ307433B6 (cs) | 2001-09-12 | 2018-08-22 | Leadiant Biosciences Sa | Deriváty částečně desulfátovaných glykosaminoglykanů jako inhibitory heparanázy mající antiangiogenní účinky a zabraňující antikoagulačnímu působení |
| WO2009151569A2 (en) * | 2008-06-09 | 2009-12-17 | Combinatorx, Incorporated | Beta adrenergic receptor agonists for the treatment of b-cell proliferative disorders |
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2016
- 2016-03-03 KR KR1020177026179A patent/KR20170138405A/ko not_active Withdrawn
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- 2016-03-03 EP EP16709148.7A patent/EP3265075B1/en active Active
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- 2016-03-03 EP EP18202120.4A patent/EP3453389A1/en not_active Withdrawn
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- 2016-03-03 BR BR112017018869A patent/BR112017018869A2/pt not_active IP Right Cessation
- 2016-03-03 HU HUE16709148A patent/HUE042681T2/hu unknown
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Also Published As
| Publication number | Publication date |
|---|---|
| PL3265075T3 (pl) | 2020-10-05 |
| CN107645954A (zh) | 2018-01-30 |
| EP3265075B1 (en) | 2018-12-12 |
| US20180050061A1 (en) | 2018-02-22 |
| ES2715556T3 (es) | 2019-06-04 |
| MX2017011093A (es) | 2018-02-19 |
| EP3453389A1 (en) | 2019-03-13 |
| HK1245107A1 (zh) | 2018-08-24 |
| US10576101B2 (en) | 2020-03-03 |
| HUE042681T2 (hu) | 2019-07-29 |
| BR112017018869A2 (pt) | 2018-04-17 |
| KR20170138405A (ko) | 2017-12-15 |
| CA2978040A1 (en) | 2016-09-15 |
| AU2016230859A1 (en) | 2017-08-17 |
| PT3265075T (pt) | 2019-03-25 |
| EP3265075A1 (en) | 2018-01-10 |
| WO2016142814A1 (en) | 2016-09-15 |
| JP2018512394A (ja) | 2018-05-17 |
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| EA039396B1 (ru) | Лечение рака молочной железы с тройным негативным фенотипом ингибиторами tor-киназы |