HUE042681T2 - Myeloma multiplex roneparstat kombinációs terápiája - Google Patents

Myeloma multiplex roneparstat kombinációs terápiája

Info

Publication number
HUE042681T2
HUE042681T2 HUE16709148A HUE16709148A HUE042681T2 HU E042681 T2 HUE042681 T2 HU E042681T2 HU E16709148 A HUE16709148 A HU E16709148A HU E16709148 A HUE16709148 A HU E16709148A HU E042681 T2 HUE042681 T2 HU E042681T2
Authority
HU
Hungary
Prior art keywords
roneparstat
multiple myeloma
combined therapy
therapy
combined
Prior art date
Application number
HUE16709148A
Other languages
English (en)
Inventor
Ralph D Sanderson
C Ramani Vishnu Prakash
Alessandro Noseda
Paola Barbieri
Original Assignee
Leadiant Biosciences Sa In Liquidazione
Uab Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leadiant Biosciences Sa In Liquidazione, Uab Res Found filed Critical Leadiant Biosciences Sa In Liquidazione
Publication of HUE042681T2 publication Critical patent/HUE042681T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727Heparin; Heparan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HUE16709148A 2015-03-06 2016-03-03 Myeloma multiplex roneparstat kombinációs terápiája HUE042681T2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562129221P 2015-03-06 2015-03-06
US201562153899P 2015-04-28 2015-04-28

Publications (1)

Publication Number Publication Date
HUE042681T2 true HUE042681T2 (hu) 2019-07-29

Family

ID=55521766

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE16709148A HUE042681T2 (hu) 2015-03-06 2016-03-03 Myeloma multiplex roneparstat kombinációs terápiája

Country Status (16)

Country Link
US (1) US10576101B2 (hu)
EP (2) EP3265075B1 (hu)
JP (1) JP2018512394A (hu)
KR (1) KR20170138405A (hu)
CN (1) CN107645954A (hu)
AU (1) AU2016230859A1 (hu)
BR (1) BR112017018869A2 (hu)
CA (1) CA2978040A1 (hu)
DK (1) DK3265075T3 (hu)
ES (1) ES2715556T3 (hu)
HK (1) HK1245107A1 (hu)
HU (1) HUE042681T2 (hu)
MX (1) MX2017011093A (hu)
PL (1) PL3265075T3 (hu)
PT (1) PT3265075T (hu)
WO (1) WO2016142814A1 (hu)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8727157D0 (en) * 1987-11-19 1987-12-23 Wellcome Found Pharmaceutical formulations
US7781416B2 (en) 2000-01-25 2010-08-24 Sigma-Tau Research Switzerland S.A. Derivatives of partially desulphated glycosaminoglycans as heparanase inhibitors, endowed with antiangiogenic activity and devoid of anticoagulating effect
IT1316986B1 (it) 2000-01-25 2003-05-26 Sigma Tau Ind Farmaceuti Derivati glicosamminoglicani parzialmente desolfatati nonanticoagulanti ad attivita' antiangiogenica.
EP2343077B1 (en) 2001-09-12 2013-07-17 SIGMA-TAU Research Switzerland S.A. Derivatives of totally N-desulphated glycosaminoglycans as heparanase inhibitors, endowed with antiangiogenic activity and devoid of anticoagulating effect
US20100009934A1 (en) 2008-06-09 2010-01-14 Combinatorx, Incorporated Beta adrenergic receptor agonists for the treatment of b-cell proliferative disorders

Also Published As

Publication number Publication date
EP3453389A1 (en) 2019-03-13
CA2978040A1 (en) 2016-09-15
DK3265075T3 (en) 2019-04-08
ES2715556T3 (es) 2019-06-04
JP2018512394A (ja) 2018-05-17
HK1245107A1 (zh) 2018-08-24
BR112017018869A2 (pt) 2018-04-17
US10576101B2 (en) 2020-03-03
AU2016230859A1 (en) 2017-08-17
CN107645954A (zh) 2018-01-30
KR20170138405A (ko) 2017-12-15
EP3265075A1 (en) 2018-01-10
US20180050061A1 (en) 2018-02-22
PT3265075T (pt) 2019-03-25
MX2017011093A (es) 2018-02-19
EP3265075B1 (en) 2018-12-12
PL3265075T3 (pl) 2020-10-05
WO2016142814A1 (en) 2016-09-15

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