MX2017011093A - Terapia combinada de roneparstat para mieloma multiple. - Google Patents
Terapia combinada de roneparstat para mieloma multiple.Info
- Publication number
- MX2017011093A MX2017011093A MX2017011093A MX2017011093A MX2017011093A MX 2017011093 A MX2017011093 A MX 2017011093A MX 2017011093 A MX2017011093 A MX 2017011093A MX 2017011093 A MX2017011093 A MX 2017011093A MX 2017011093 A MX2017011093 A MX 2017011093A
- Authority
- MX
- Mexico
- Prior art keywords
- roneparstat
- multiple myeloma
- combined therapy
- combined
- carfilzomib
- Prior art date
Links
- YUQCJZVVMQZBFE-JPUFUMQZSA-N CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@@H]1O[C@H]2[C@@H]([C@H]([C@@H](OC2C(=O)O)O[C@@H]3[C@H](O[C@@H]([C@@H]([C@H]3O)NC(=O)C)O[C@@H](CO)C(C(=O)O)O[C@@H](CO)O)CO)OS(=O)(=O)O)O)CO)O)O Chemical compound CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@@H]1O[C@H]2[C@@H]([C@H]([C@@H](OC2C(=O)O)O[C@@H]3[C@H](O[C@@H]([C@@H]([C@H]3O)NC(=O)C)O[C@@H](CO)C(C(=O)O)O[C@@H](CO)O)CO)OS(=O)(=O)O)O)CO)O)O YUQCJZVVMQZBFE-JPUFUMQZSA-N 0.000 title abstract 3
- 229950003179 roneparstat Drugs 0.000 title abstract 3
- 208000034578 Multiple myelomas Diseases 0.000 title abstract 2
- 206010035226 Plasma cell myeloma Diseases 0.000 title abstract 2
- 238000002648 combination therapy Methods 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 229940079156 Proteasome inhibitor Drugs 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229960001467 bortezomib Drugs 0.000 abstract 1
- GXJABQQUPOEUTA-RDJZCZTQSA-N bortezomib Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)B(O)O)NC(=O)C=1N=CC=NC=1)C1=CC=CC=C1 GXJABQQUPOEUTA-RDJZCZTQSA-N 0.000 abstract 1
- 229960002438 carfilzomib Drugs 0.000 abstract 1
- BLMPQMFVWMYDKT-NZTKNTHTSA-N carfilzomib Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC(C)C)C(=O)[C@]1(C)OC1)NC(=O)CN1CCOCC1)CC1=CC=CC=C1 BLMPQMFVWMYDKT-NZTKNTHTSA-N 0.000 abstract 1
- 108010021331 carfilzomib Proteins 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- SGDBTWWWUNNDEQ-LBPRGKRZSA-N melphalan Chemical compound OC(=O)[C@@H](N)CC1=CC=C(N(CCCl)CCCl)C=C1 SGDBTWWWUNNDEQ-LBPRGKRZSA-N 0.000 abstract 1
- 229960001924 melphalan Drugs 0.000 abstract 1
- 239000003207 proteasome inhibitor Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562129221P | 2015-03-06 | 2015-03-06 | |
| US201562153899P | 2015-04-28 | 2015-04-28 | |
| PCT/IB2016/051196 WO2016142814A1 (en) | 2015-03-06 | 2016-03-03 | Roneparstat combined therapy of multiple myeloma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2017011093A true MX2017011093A (es) | 2018-02-19 |
Family
ID=55521766
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017011093A MX2017011093A (es) | 2015-03-06 | 2016-03-03 | Terapia combinada de roneparstat para mieloma multiple. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US10576101B2 (enExample) |
| EP (2) | EP3453389A1 (enExample) |
| JP (1) | JP2018512394A (enExample) |
| KR (1) | KR20170138405A (enExample) |
| CN (1) | CN107645954A (enExample) |
| AU (1) | AU2016230859A1 (enExample) |
| BR (1) | BR112017018869A2 (enExample) |
| CA (1) | CA2978040A1 (enExample) |
| DK (1) | DK3265075T3 (enExample) |
| ES (1) | ES2715556T3 (enExample) |
| HK (1) | HK1245107A1 (enExample) |
| HU (1) | HUE042681T2 (enExample) |
| MX (1) | MX2017011093A (enExample) |
| PL (1) | PL3265075T3 (enExample) |
| PT (1) | PT3265075T (enExample) |
| WO (1) | WO2016142814A1 (enExample) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8727157D0 (en) * | 1987-11-19 | 1987-12-23 | Wellcome Found | Pharmaceutical formulations |
| US7781416B2 (en) | 2000-01-25 | 2010-08-24 | Sigma-Tau Research Switzerland S.A. | Derivatives of partially desulphated glycosaminoglycans as heparanase inhibitors, endowed with antiangiogenic activity and devoid of anticoagulating effect |
| IT1316986B1 (it) | 2000-01-25 | 2003-05-26 | Sigma Tau Ind Farmaceuti | Derivati glicosamminoglicani parzialmente desolfatati nonanticoagulanti ad attivita' antiangiogenica. |
| EP1427427B1 (en) | 2001-09-12 | 2011-06-08 | SIGMA-TAU Research Switzerland S.A. | Derivatives of partially desulphated glycosaminoglycans as heparanase inhibitors, endowed with antiangiogenic activity and devoid of anticoagulating effect |
| US20100009934A1 (en) | 2008-06-09 | 2010-01-14 | Combinatorx, Incorporated | Beta adrenergic receptor agonists for the treatment of b-cell proliferative disorders |
-
2016
- 2016-03-03 EP EP18202120.4A patent/EP3453389A1/en not_active Withdrawn
- 2016-03-03 HU HUE16709148A patent/HUE042681T2/hu unknown
- 2016-03-03 PL PL16709148T patent/PL3265075T3/pl unknown
- 2016-03-03 MX MX2017011093A patent/MX2017011093A/es unknown
- 2016-03-03 KR KR1020177026179A patent/KR20170138405A/ko not_active Withdrawn
- 2016-03-03 DK DK16709148.7T patent/DK3265075T3/en active
- 2016-03-03 EP EP16709148.7A patent/EP3265075B1/en active Active
- 2016-03-03 AU AU2016230859A patent/AU2016230859A1/en not_active Abandoned
- 2016-03-03 WO PCT/IB2016/051196 patent/WO2016142814A1/en not_active Ceased
- 2016-03-03 CA CA2978040A patent/CA2978040A1/en not_active Abandoned
- 2016-03-03 CN CN201680012508.0A patent/CN107645954A/zh active Pending
- 2016-03-03 HK HK18104587.1A patent/HK1245107A1/zh unknown
- 2016-03-03 US US15/556,183 patent/US10576101B2/en not_active Expired - Fee Related
- 2016-03-03 JP JP2017546847A patent/JP2018512394A/ja active Pending
- 2016-03-03 PT PT16709148T patent/PT3265075T/pt unknown
- 2016-03-03 BR BR112017018869A patent/BR112017018869A2/pt not_active IP Right Cessation
- 2016-03-03 ES ES16709148T patent/ES2715556T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3265075B1 (en) | 2018-12-12 |
| CN107645954A (zh) | 2018-01-30 |
| PT3265075T (pt) | 2019-03-25 |
| KR20170138405A (ko) | 2017-12-15 |
| CA2978040A1 (en) | 2016-09-15 |
| ES2715556T3 (es) | 2019-06-04 |
| HUE042681T2 (hu) | 2019-07-29 |
| EP3453389A1 (en) | 2019-03-13 |
| JP2018512394A (ja) | 2018-05-17 |
| WO2016142814A1 (en) | 2016-09-15 |
| HK1245107A1 (zh) | 2018-08-24 |
| US10576101B2 (en) | 2020-03-03 |
| PL3265075T3 (pl) | 2020-10-05 |
| DK3265075T3 (en) | 2019-04-08 |
| AU2016230859A1 (en) | 2017-08-17 |
| BR112017018869A2 (pt) | 2018-04-17 |
| EP3265075A1 (en) | 2018-01-10 |
| US20180050061A1 (en) | 2018-02-22 |
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