DK3262059T3 - Platforme til screening af kemisk kodede, rumligt adresserede biblioteker - Google Patents

Platforme til screening af kemisk kodede, rumligt adresserede biblioteker Download PDF

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Publication number
DK3262059T3
DK3262059T3 DK16756316.2T DK16756316T DK3262059T3 DK 3262059 T3 DK3262059 T3 DK 3262059T3 DK 16756316 T DK16756316 T DK 16756316T DK 3262059 T3 DK3262059 T3 DK 3262059T3
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DK
Denmark
Prior art keywords
spaciously
platforms
coded
screening chemical
libraries
Prior art date
Application number
DK16756316.2T
Other languages
Danish (da)
English (en)
Inventor
Jacob Berlin
Gregory COPELAND
Kathleen Elison
Hurik Muradyan
Original Assignee
Hope City
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56789474&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3262059(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hope City filed Critical Hope City
Application granted granted Critical
Publication of DK3262059T3 publication Critical patent/DK3262059T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/14Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
    • C40B50/16Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support involving encoding steps
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B70/00Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1065Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/10Libraries containing peptides or polypeptides, or derivatives thereof
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346Nanoparticles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Plant Pathology (AREA)
  • Structural Engineering (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Signal Processing For Digital Recording And Reproducing (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK16756316.2T 2015-02-24 2016-02-24 Platforme til screening af kemisk kodede, rumligt adresserede biblioteker DK3262059T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562120262P 2015-02-24 2015-02-24
PCT/US2016/019426 WO2016138184A1 (en) 2015-02-24 2016-02-24 Chemically encoded spatially addressed library screening platforms

Publications (1)

Publication Number Publication Date
DK3262059T3 true DK3262059T3 (da) 2022-01-31

Family

ID=56789474

Family Applications (3)

Application Number Title Priority Date Filing Date
DK16756316.2T DK3262059T3 (da) 2015-02-24 2016-02-24 Platforme til screening af kemisk kodede, rumligt adresserede biblioteker
DK19196007.9T DK3650458T5 (da) 2015-02-24 2016-02-24 Platforme til screening af kemisk kodede, rumligt adresserede biblioteker
DK19196019.4T DK3650459T5 (da) 2015-02-24 2016-02-24 Kemisk kodede, rumligt adresserede bibliotekscreeningsplatforme

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK19196007.9T DK3650458T5 (da) 2015-02-24 2016-02-24 Platforme til screening af kemisk kodede, rumligt adresserede biblioteker
DK19196019.4T DK3650459T5 (da) 2015-02-24 2016-02-24 Kemisk kodede, rumligt adresserede bibliotekscreeningsplatforme

Country Status (19)

Country Link
US (6) US10760181B2 (enExample)
EP (4) EP3262059B1 (enExample)
JP (2) JP6872501B2 (enExample)
AU (2) AU2016222755B2 (enExample)
CA (1) CA2976946C (enExample)
CY (1) CY1124954T1 (enExample)
DK (3) DK3262059T3 (enExample)
ES (3) ES2965764T3 (enExample)
FI (2) FI3650458T3 (enExample)
HR (3) HRP20231536T1 (enExample)
HU (3) HUE058813T2 (enExample)
LT (3) LT3262059T (enExample)
NZ (1) NZ734644A (enExample)
PL (3) PL3650458T3 (enExample)
PT (3) PT3650459T (enExample)
RS (3) RS62847B1 (enExample)
SI (3) SI3262059T1 (enExample)
SM (3) SMT202300275T1 (enExample)
WO (1) WO2016138184A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2622112B2 (ja) 1986-09-26 1997-06-18 キヤノン株式会社 画像処理システム
WO2009069203A1 (ja) * 2007-11-28 2009-06-04 Glory Ltd. チケット処理装置、チケット処理システム及びチケット処理方法
SI3262059T1 (sl) 2015-02-24 2022-04-29 City Of Hope Kemično kodirane prostorsko naslovljene platforme za pregledovanje knjižnic
WO2016165621A1 (zh) * 2015-04-14 2016-10-20 成都先导药物开发有限公司 一种固相合成dna编码化合物库的方法
US20190264199A1 (en) * 2016-11-08 2019-08-29 Nanna Therapeutics Limited Tagless encoded chemical library
CN115506034B (zh) 2017-09-25 2025-12-05 普莱克斯姆公司 寡核苷酸编码的化学文库
SG11202003923PA (en) 2017-10-31 2020-05-28 Encodia Inc Methods and kits using nucleic acid encoding and/or label
AU2020361681A1 (en) 2019-10-10 2022-05-05 1859, Inc. Methods and systems for microfluidic screening
US12577702B2 (en) 2020-01-28 2026-03-17 Plexium, Inc. Oligonucleotide encoded chemical libraries, related systems, devices, and methods for detecting, analyzing, quantifying, and testing biologics/genetics
WO2022170034A1 (en) * 2021-02-05 2022-08-11 Affinergy, Llc Rapid assay for apol1 g0 protein
US20250368840A1 (en) * 2021-08-27 2025-12-04 National University Corporation Kobe University Core-shell template molecule/particle for technique for high-yield formation of pores on substrate

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4672040A (en) * 1983-05-12 1987-06-09 Advanced Magnetics, Inc. Magnetic particles for use in separations
US5034506A (en) 1985-03-15 1991-07-23 Anti-Gene Development Group Uncharged morpholino-based polymers having achiral intersubunit linkages
US5235033A (en) 1985-03-15 1993-08-10 Anti-Gene Development Group Alpha-morpholino ribonucleoside derivatives and polymers thereof
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
DK0604552T3 (da) 1991-09-18 1997-08-04 Affymax Tech Nv Fremgangsmåde til syntese af forskellige samlinger af oligomerer
US5573905A (en) 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
US5565324A (en) 1992-10-01 1996-10-15 The Trustees Of Columbia University In The City Of New York Complex combinatorial chemical libraries encoded with tags
EP0675873A4 (en) * 1992-12-11 2000-03-29 Chiron Corp PRODUCTION OF CODED POLYMERS
WO1994028028A1 (en) * 1993-05-27 1994-12-08 Selectide Corporation Topologically segregated, encoded solid phase libraries
PT1156059E (pt) * 1993-06-21 2007-10-19 Aventis Pharma Inc Ligantes cliváveis selectivamente com base num grupo de metionina e um grupo éster
US6087186A (en) * 1993-07-16 2000-07-11 Irori Methods and apparatus for synthesizing labeled combinatorial chemistry libraries
BR9407947A (pt) * 1993-11-02 1996-11-26 Affymax Tech Nv Processo para sintetizar moléculas diversas em uma pluralidade de substratos e uma coleçao molecular etiquetade para realizaçao reaçoes de copulaçao em contas em paralelo para triar uma coleçao molecular etiquetada para detectar a presença de um ou mais diferentes etiquetas e para determinar a sequência de síntese aparelho para reaçoes de copulaçao paralelas em suportes sólidos bloco de alinhamento ótico para uso com um detector ótico sistemas de distribuiçao para distribuir reagentes dispositiv
US6936477B2 (en) 1994-04-13 2005-08-30 The Trustees Of Columbia University In The City Of New York Complex combinatorial chemical libraries encoded with tags
US7615368B1 (en) 1994-06-17 2009-11-10 The Board Of Trustees Of The Leland Stanford Junior University Microarrays of polypeptides
US5807522A (en) 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
US5830645A (en) 1994-12-09 1998-11-03 The Regents Of The University Of California Comparative fluorescence hybridization to nucleic acid arrays
US5846839A (en) 1995-12-22 1998-12-08 Glaxo Group Limited Methods for hard-tagging an encoded synthetic library
ES2288760T3 (es) * 1996-04-25 2008-01-16 Bioarray Solutions Ltd. Ensamblaje electrocinetico controlado por luz de particulas proximas a superficies.
CN1230216A (zh) 1996-07-08 1999-09-29 伯斯坦恩实验室股份有限公司 可断裂信号元件装置和方法
ATE204290T1 (de) 1996-11-06 2001-09-15 Sequenom Inc Zusammensetzungen und verfahren zur immobilisierung von nukleinsäure auf festträgern
US7060431B2 (en) 1998-06-24 2006-06-13 Illumina, Inc. Method of making and decoding of array sensors with microspheres
US6429027B1 (en) * 1998-12-28 2002-08-06 Illumina, Inc. Composite arrays utilizing microspheres
US20020150909A1 (en) * 1999-02-09 2002-10-17 Stuelpnagel John R. Automated information processing in randomly ordered arrays
US6824987B1 (en) 1999-05-11 2004-11-30 President And Fellows Of Harvard College Small molecule printing
US7932213B2 (en) 1999-05-11 2011-04-26 President And Fellows Of Harvard College Small molecule printing
US6544732B1 (en) * 1999-05-20 2003-04-08 Illumina, Inc. Encoding and decoding of array sensors utilizing nanocrystals
US7160735B2 (en) 2000-04-28 2007-01-09 Monogram Biosciences, Inc. Tagged microparticle compositions and methods
JP3899831B2 (ja) * 2001-03-02 2007-03-28 株式会社日立製作所 生化学センサ及びこれを用いた生化学検査装置
US20060040286A1 (en) * 2001-03-28 2006-02-23 Nanosphere, Inc. Bio-barcode based detection of target analytes
US20030027221A1 (en) 2001-04-06 2003-02-06 Scott Melissa E. High-throughput screening assays by encapsulation
US20030228619A1 (en) * 2002-06-10 2003-12-11 Xenoport, Inc. Peptide nucleic acids as tags in encoded libraries
US7422855B2 (en) * 2004-06-10 2008-09-09 Perkinelmer Las, Inc. Multiplexing assays for analyte detection
US20060134697A1 (en) * 2004-10-28 2006-06-22 The Regents Of The University Of California Method of preparing coded compound libraries
EP1931943A2 (en) * 2005-09-16 2008-06-18 The Regents of the University of California A colorimetric bio-barcode amplification assay for analyte detection
MX2011008383A (es) 2009-02-10 2011-09-06 Idera Pharmaceuticals Inc Agonistas basados en acido ribonucleico sintetico de receptor 7 tipo toll.
US9172561B2 (en) 2009-07-29 2015-10-27 Qualcomm Incorporated Adaptive transmissions in coordinated multiple point communications
US20120129248A1 (en) * 2009-07-31 2012-05-24 Prognosys Biosciences, Inc. Assay tools and methods of use
US20130059741A1 (en) 2010-05-13 2013-03-07 Illumina, Inc. Binding assays for markers
WO2014026283A1 (en) 2012-08-14 2014-02-20 Angiochem Inc. Peptide-dendrimer conjugates and uses thereof
EP2888571B1 (en) * 2012-08-23 2022-12-21 Stemcell Technologies Inc. Methods and kits for rapid and reversible biomolecular labeling
SI3262059T1 (sl) * 2015-02-24 2022-04-29 City Of Hope Kemično kodirane prostorsko naslovljene platforme za pregledovanje knjižnic

Also Published As

Publication number Publication date
CA2976946A1 (en) 2016-09-01
HUE063406T2 (hu) 2024-01-28
CY1124954T1 (el) 2023-01-05
EP3650459A1 (en) 2020-05-13
JP7109618B6 (ja) 2022-08-22
AU2016222755A1 (en) 2017-08-31
ES2965764T3 (es) 2024-04-16
EP3650458B1 (en) 2023-08-09
EP3650459B1 (en) 2023-09-06
HRP20220093T1 (hr) 2022-04-15
WO2016138184A1 (en) 2016-09-01
FI3650459T3 (fi) 2023-11-28
US20180245241A1 (en) 2018-08-30
AU2021200399B2 (en) 2023-04-20
JP6872501B2 (ja) 2021-05-19
FI3650458T3 (fi) 2023-08-21
RS62847B1 (sr) 2022-02-28
US11015266B2 (en) 2021-05-25
LT3650458T (lt) 2023-10-10
SMT202200039T1 (it) 2022-03-21
DK3650459T3 (da) 2023-12-11
ES2954467T3 (es) 2023-11-22
DK3650458T5 (da) 2024-08-26
EP3650458A1 (en) 2020-05-13
US11015265B2 (en) 2021-05-25
DK3650459T5 (da) 2024-08-26
PT3650458T (pt) 2023-08-31
PL3650459T3 (pl) 2024-02-26
RS64567B1 (sr) 2023-10-31
NZ772386A (en) 2024-10-25
US20210324538A1 (en) 2021-10-21
PL3650458T3 (pl) 2023-11-06
EP4276059A2 (en) 2023-11-15
US20190390367A1 (en) 2019-12-26
NZ734644A (en) 2023-02-24
PT3262059T (pt) 2022-01-27
SMT202300430T1 (it) 2024-01-10
EP3262059A4 (en) 2018-12-05
DK3650458T3 (da) 2023-09-04
US20200378032A1 (en) 2020-12-03
HUE058813T2 (hu) 2022-09-28
SI3650458T1 (sl) 2023-11-30
SI3262059T1 (sl) 2022-04-29
RS64899B1 (sr) 2023-12-29
HRP20230928T1 (hr) 2023-11-24
JP7109618B2 (ja) 2022-07-29
EP3262059A1 (en) 2018-01-03
ES2904997T3 (es) 2022-04-06
SMT202300275T1 (it) 2023-11-13
HUE064689T2 (hu) 2024-04-28
LT3650459T (lt) 2023-12-27
EP4276059A3 (en) 2024-05-01
JP2018505700A (ja) 2018-03-01
HRP20231536T1 (hr) 2024-03-15
US10760181B2 (en) 2020-09-01
LT3262059T (lt) 2022-02-25
US12624476B2 (en) 2026-05-12
US20200378031A1 (en) 2020-12-03
PL3262059T3 (pl) 2022-02-21
AU2016222755B2 (en) 2021-02-18
US10767278B2 (en) 2020-09-08
JP2021106607A (ja) 2021-07-29
SI3650459T1 (sl) 2024-04-30
EP3262059B1 (en) 2022-01-05
PT3650459T (pt) 2023-12-06
US20220341059A1 (en) 2022-10-27
AU2021200399A1 (en) 2021-03-18
CA2976946C (en) 2023-09-19

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