DK3171866T3 - Behandling af androgen deprivationsterapi-inducerede hedeture og knogletab ved anvendelse af cis-clomiphen - Google Patents

Behandling af androgen deprivationsterapi-inducerede hedeture og knogletab ved anvendelse af cis-clomiphen Download PDF

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Publication number
DK3171866T3
DK3171866T3 DK15824708.0T DK15824708T DK3171866T3 DK 3171866 T3 DK3171866 T3 DK 3171866T3 DK 15824708 T DK15824708 T DK 15824708T DK 3171866 T3 DK3171866 T3 DK 3171866T3
Authority
DK
Denmark
Prior art keywords
clomiphen
trips
cis
treatment
bone loss
Prior art date
Application number
DK15824708.0T
Other languages
English (en)
Inventor
Mitchell STEINER
Harry Fisch
Original Assignee
Aspen Park Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aspen Park Pharmaceuticals Inc filed Critical Aspen Park Pharmaceuticals Inc
Application granted granted Critical
Publication of DK3171866T3 publication Critical patent/DK3171866T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK15824708.0T 2014-07-24 2015-07-23 Behandling af androgen deprivationsterapi-inducerede hedeture og knogletab ved anvendelse af cis-clomiphen DK3171866T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462028540P 2014-07-24 2014-07-24
PCT/US2015/041761 WO2016014812A1 (en) 2014-07-24 2015-07-23 Treating androgen deprivation therapy induced hot flashes and bone loss using cis-clomiphene

Publications (1)

Publication Number Publication Date
DK3171866T3 true DK3171866T3 (da) 2020-11-09

Family

ID=55163768

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15824708.0T DK3171866T3 (da) 2014-07-24 2015-07-23 Behandling af androgen deprivationsterapi-inducerede hedeture og knogletab ved anvendelse af cis-clomiphen

Country Status (19)

Country Link
US (3) US9913815B2 (da)
EP (2) EP3171866B1 (da)
JP (1) JP6743001B2 (da)
KR (2) KR20230005415A (da)
CN (2) CN111346076A (da)
AU (1) AU2015292519B2 (da)
CY (1) CY1123861T1 (da)
DK (1) DK3171866T3 (da)
ES (1) ES2828305T3 (da)
HR (1) HRP20201726T1 (da)
HU (1) HUE051442T2 (da)
IL (2) IL249989B (da)
LT (1) LT3171866T (da)
MX (1) MX2017000886A (da)
PL (1) PL3171866T3 (da)
PT (1) PT3171866T (da)
RU (2) RU2020120156A (da)
UA (1) UA121971C2 (da)
WO (1) WO2016014812A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2017000886A (es) 2014-07-24 2017-08-10 Aspen Park Pharmaceuticals Inc Tratamiento con cis-clomifeno de sofocos y perdida osea inducidos por privacion de androgeno terapeutica.
FR3082842A1 (fr) * 2018-06-21 2019-12-27 Veru Inc. Polymorphe de cis-clomiphene (zuclomiphene) et procedes d'utilisation de celui-ci
CA3098552A1 (en) 2019-11-14 2021-05-14 Apotex Inc. Processes for the preparation of zuclomiphene and intermediates thereof
CA3098725A1 (en) 2019-11-14 2021-05-14 Apotex Inc. Zuclpomiphene salts and crystalline forms thereof
CA3105944A1 (en) 2020-01-22 2021-07-22 Apotex Inc. Crystalline forms of zuclomiphene citrate

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT951631B (it) 1971-03-18 1973-07-10 Richardson Merrell Spa Composti utili per la separazione di isomeri ottici geometrici e strutturali e relativo procedimen to di sintesi
US4729999A (en) * 1984-10-12 1988-03-08 Bcm Technologies Antiestrogen therapy for symptoms of estrogen deficiency
US20040214898A1 (en) 2001-11-29 2004-10-28 Steiner Mitchell S. Methods for treating hot flashes
US20040213841A1 (en) * 2001-11-29 2004-10-28 Steiner Mitchell S Methods for treating hot flashes and gynecomastia
CA2468719C (en) * 2001-11-29 2011-05-24 Gtx Inc. Prevention and treatment of androgen-deprivation induced osteoporosis
US6762524B2 (en) * 2002-08-01 2004-07-13 Albert Six Magnetic drive system for a vehicle differential
ZA200706016B (en) * 2004-12-21 2008-12-31 Musc Found For Res Dev Compositions and methods for promoting wound healing and tissue regeneration
US8158828B2 (en) * 2005-11-28 2012-04-17 Gtx, Inc. Nuclear receptor binding agents
US8637706B2 (en) * 2005-11-28 2014-01-28 Gtx, Inc. Nuclear receptor binding agents
US20090215733A1 (en) * 2008-02-26 2009-08-27 Michael Charles Scally Therapy for the prophylaxis or treatment of adverse body composition changes and/or decreased muscle strength after androgen or gnrh analogue intake
MX2017000886A (es) * 2014-07-24 2017-08-10 Aspen Park Pharmaceuticals Inc Tratamiento con cis-clomifeno de sofocos y perdida osea inducidos por privacion de androgeno terapeutica.

Also Published As

Publication number Publication date
WO2016014812A1 (en) 2016-01-28
LT3171866T (lt) 2020-12-28
RU2725086C2 (ru) 2020-06-29
IL249989A0 (en) 2017-03-30
CN111346076A (zh) 2020-06-30
JP6743001B2 (ja) 2020-08-19
KR20170040797A (ko) 2017-04-13
EP3171866B1 (en) 2020-08-19
MX2017000886A (es) 2017-08-10
EP3171866A1 (en) 2017-05-31
AU2015292519B2 (en) 2020-09-03
PT3171866T (pt) 2020-10-21
IL290004A (en) 2022-03-01
US10463635B2 (en) 2019-11-05
HUE051442T2 (hu) 2021-03-01
HRP20201726T1 (hr) 2021-01-08
EP3769756A1 (en) 2021-01-27
US20170202788A1 (en) 2017-07-20
US10758500B2 (en) 2020-09-01
US20180153829A1 (en) 2018-06-07
RU2020120156A (ru) 2020-07-03
CY1123861T1 (el) 2022-03-24
US20200085768A1 (en) 2020-03-19
RU2017105837A (ru) 2018-08-30
KR20230005415A (ko) 2023-01-09
JP2017522389A (ja) 2017-08-10
PL3171866T3 (pl) 2021-04-06
RU2017105837A3 (da) 2019-03-11
UA121971C2 (uk) 2020-08-25
AU2015292519A1 (en) 2017-02-02
EP3171866A4 (en) 2017-12-27
IL249989B (en) 2022-03-01
ES2828305T3 (es) 2021-05-26
CN107072969A (zh) 2017-08-18
US9913815B2 (en) 2018-03-13
CN107072969B (zh) 2020-04-21

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