DK3558280T3 - Forebyggelse og behandling af migræne - Google Patents

Forebyggelse og behandling af migræne Download PDF

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Publication number
DK3558280T3
DK3558280T3 DK17832224.4T DK17832224T DK3558280T3 DK 3558280 T3 DK3558280 T3 DK 3558280T3 DK 17832224 T DK17832224 T DK 17832224T DK 3558280 T3 DK3558280 T3 DK 3558280T3
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DK
Denmark
Prior art keywords
migraines
prevention
treatment
Prior art date
Application number
DK17832224.4T
Other languages
English (en)
Inventor
Elena Gross
Dirk Fischer
Original Assignee
Univ Kinderspital Beider Basel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of DK3558280T3 publication Critical patent/DK3558280T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/194Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/191Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
DK17832224.4T 2016-12-21 2017-12-20 Forebyggelse og behandling af migræne DK3558280T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16206018 2016-12-21
EP17154258 2017-02-01
PCT/EP2017/083880 WO2018115158A1 (en) 2016-12-21 2017-12-20 Migraine prevention and treatment

Publications (1)

Publication Number Publication Date
DK3558280T3 true DK3558280T3 (da) 2023-08-21

Family

ID=61005774

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17832224.4T DK3558280T3 (da) 2016-12-21 2017-12-20 Forebyggelse og behandling af migræne

Country Status (17)

Country Link
US (2) US11166928B2 (da)
EP (2) EP3558280B1 (da)
JP (2) JP2020504746A (da)
KR (1) KR102610870B1 (da)
CN (1) CN110087642B (da)
AU (2) AU2017384625B2 (da)
CA (1) CA3046415A1 (da)
DK (1) DK3558280T3 (da)
ES (1) ES2948609T3 (da)
FI (1) FI3558280T3 (da)
HR (1) HRP20230851T1 (da)
HU (1) HUE062536T2 (da)
LT (1) LT3558280T (da)
PL (1) PL3558280T3 (da)
RU (1) RU2753057C9 (da)
SI (1) SI3558280T1 (da)
WO (1) WO2018115158A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180057846A1 (en) 2016-08-30 2018-03-01 KetoneAid Inc. Partially buffered free acid and/or ketone blend for rapid onset ketosis and metabolic therapy
SI3558280T1 (sl) * 2016-12-21 2023-10-30 Universitaets-Kinderspital Beider Basel Preprečevanje in zdravljenje migrene
US20180177753A1 (en) 2016-12-23 2018-06-28 Neuroenergy Ventures, Inc. Glyceryl 3-hydroxybutyrates for migraine symptom management
US11760963B2 (en) 2017-08-23 2023-09-19 KetoneAid Inc. Ketogenic beer and alcoholic beverage mixture containing non-racemic ethyl 3-hydroxybutyrate and/or 1,3 butanediol
CA3134246A1 (en) * 2019-03-22 2020-10-01 Societe Des Produits Nestle S.A. Methods using administration of medium chain triglycerides (mct) prior to a meal to increase ketone production from the mcts
AU2020274805A1 (en) 2019-05-10 2021-10-28 Ketoswiss Ag Ketone bodies enclosed in microbeads
US20220315520A1 (en) * 2019-06-12 2022-10-06 Ioi Oleo Gmbh Process for preparing acyl-capped 3-hydroxycarboxylic acids and their salts and esters
WO2020249198A1 (de) * 2019-06-12 2020-12-17 Ioi Oleo Gmbh Verfahren zur herstellung von polyolbasierten estern von acylverkappten 3-hydroxycarbonsäuren
BR112023025213A2 (pt) 2021-07-17 2024-02-27 Ketoswiss Ag Combinação de um corpo cetônico ou composto cetogênico com um analgésico ou antioxidante
WO2023166069A1 (en) 2022-03-02 2023-09-07 N.V. Nutricia Fatty acids for ketosis control

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985003872A1 (en) 1984-03-01 1985-09-12 Vernon Erk Method of lowering blood sugar level in vertebrates
JPH0665458A (ja) 1992-08-21 1994-03-08 Nippon Oil & Fats Co Ltd 塩素含有樹脂組成物
US5420335A (en) * 1993-09-30 1995-05-30 Birkhahn; Ronald H. Parenteral nutrients based on watersoluble glycerol bisacetoacetates
DK2283834T3 (da) * 1997-03-17 2016-08-15 Btg Int Ltd Terapeutiske sammensætninger omfattende ketonforbindelser og forstadier deraf
KR100805490B1 (ko) 1998-09-15 2008-02-20 비티지 인터내셔널 리미티드 치료 조성물 (ⅱ)
US20050129783A1 (en) * 2001-04-19 2005-06-16 Mccleary Edward L. Composition and method for treatment of neurophysiological conditions and maintenance of neurophysiological health
WO2008005818A1 (en) * 2006-06-30 2008-01-10 Stepan Co Glyceride esters for the treatment of diseases associated with reduced neuronal metabolism of glucose
WO2010084356A1 (en) 2009-01-24 2010-07-29 Phytopharm Plc Treatment of neurotrophic factor mediated disorders
GB201206192D0 (en) * 2012-04-05 2012-05-23 Tdeltas Ltd Ketone bodies and ketone body esters and for maintaining or improving muscle power output
CN103877118A (zh) 2014-03-11 2014-06-25 天津金耀集团有限公司 一种由醋丙甲泼尼龙、氧化锌组成的药物组合物
US20160078782A1 (en) * 2014-09-17 2016-03-17 The Trustees Of Boston College Glucose Ketone Index for MetabolicTherapy
EP3322427A4 (en) 2015-07-10 2019-07-17 Cognate Nutritionals, Inc. MIGRAINE PROPHYLAXIS AND MITIGATION USING MEDIUM CHAIN TRIGLYCERIDES, KETONE ESTERS, AND OTHER KETOGENIC SOURCES
SI3558280T1 (sl) * 2016-12-21 2023-10-30 Universitaets-Kinderspital Beider Basel Preprečevanje in zdravljenje migrene
US20180177753A1 (en) 2016-12-23 2018-06-28 Neuroenergy Ventures, Inc. Glyceryl 3-hydroxybutyrates for migraine symptom management
US10500182B2 (en) 2018-01-10 2019-12-10 Robert Firger Compositions of ketogenic sources, micronutrients and phytochemicals for prophylaxis and mitigation of migraine headache

Also Published As

Publication number Publication date
AU2017384625A1 (en) 2019-06-13
US20190374490A1 (en) 2019-12-12
US11166928B2 (en) 2021-11-09
PL3558280T3 (pl) 2023-10-16
EP3558280A1 (en) 2019-10-30
AU2017384625B2 (en) 2021-12-16
CA3046415A1 (en) 2018-06-28
EP4245368A2 (en) 2023-09-20
CN110087642A (zh) 2019-08-02
JP2022166218A (ja) 2022-11-01
JP2020504746A (ja) 2020-02-13
HRP20230851T1 (hr) 2023-11-10
US20210338618A1 (en) 2021-11-04
RU2753057C2 (ru) 2021-08-11
KR20190099486A (ko) 2019-08-27
KR102610870B1 (ko) 2023-12-06
SI3558280T1 (sl) 2023-10-30
FI3558280T3 (fi) 2023-07-13
EP4245368A3 (en) 2024-01-03
HUE062536T2 (hu) 2023-11-28
WO2018115158A1 (en) 2018-06-28
AU2022201565A1 (en) 2022-03-31
EP3558280B1 (en) 2023-06-07
US11890264B2 (en) 2024-02-06
LT3558280T (lt) 2023-10-10
RU2019122562A (ru) 2021-01-27
CN110087642B (zh) 2022-12-27
RU2019122562A3 (da) 2021-01-27
ES2948609T3 (es) 2023-09-14
RU2753057C9 (ru) 2021-09-10
AU2022201565B2 (en) 2023-07-06

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