LT3171866T - Androgenų deprivacijos terapijos sukeltų karščio bangų ir kaulų retėjimo gydymas cis-klomifenu - Google Patents

Androgenų deprivacijos terapijos sukeltų karščio bangų ir kaulų retėjimo gydymas cis-klomifenu

Info

Publication number
LT3171866T
LT3171866T LTEP15824708.0T LT15824708T LT3171866T LT 3171866 T LT3171866 T LT 3171866T LT 15824708 T LT15824708 T LT 15824708T LT 3171866 T LT3171866 T LT 3171866T
Authority
LT
Lithuania
Prior art keywords
clomiphene
cis
bone loss
hot flashes
androgen deprivation
Prior art date
Application number
LTEP15824708.0T
Other languages
English (en)
Inventor
Mitchell Steiner
Harry Fisch
Original Assignee
Aspen Park Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aspen Park Pharmaceuticals, Inc. filed Critical Aspen Park Pharmaceuticals, Inc.
Publication of LT3171866T publication Critical patent/LT3171866T/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
LTEP15824708.0T 2014-07-24 2015-07-23 Androgenų deprivacijos terapijos sukeltų karščio bangų ir kaulų retėjimo gydymas cis-klomifenu LT3171866T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462028540P 2014-07-24 2014-07-24
PCT/US2015/041761 WO2016014812A1 (en) 2014-07-24 2015-07-23 Treating androgen deprivation therapy induced hot flashes and bone loss using cis-clomiphene

Publications (1)

Publication Number Publication Date
LT3171866T true LT3171866T (lt) 2020-12-28

Family

ID=55163768

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP15824708.0T LT3171866T (lt) 2014-07-24 2015-07-23 Androgenų deprivacijos terapijos sukeltų karščio bangų ir kaulų retėjimo gydymas cis-klomifenu

Country Status (19)

Country Link
US (3) US9913815B2 (lt)
EP (2) EP3769756A1 (lt)
JP (1) JP6743001B2 (lt)
KR (2) KR20230005415A (lt)
CN (2) CN111346076A (lt)
AU (1) AU2015292519B2 (lt)
CY (1) CY1123861T1 (lt)
DK (1) DK3171866T3 (lt)
ES (1) ES2828305T3 (lt)
HR (1) HRP20201726T1 (lt)
HU (1) HUE051442T2 (lt)
IL (2) IL249989B (lt)
LT (1) LT3171866T (lt)
MX (1) MX2017000886A (lt)
PL (1) PL3171866T3 (lt)
PT (1) PT3171866T (lt)
RU (2) RU2020120156A (lt)
UA (1) UA121971C2 (lt)
WO (1) WO2016014812A1 (lt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2020120156A (ru) * 2014-07-24 2020-07-03 Эспен Парк Фармасьютикалз, Инк. Лечение приливов и потери костной ткани, вызванных андрогенной депривационной терапией с применением цис-кломифена
FR3082842A1 (fr) * 2018-06-21 2019-12-27 Veru Inc. Polymorphe de cis-clomiphene (zuclomiphene) et procedes d'utilisation de celui-ci
CA3098725A1 (en) 2019-11-14 2021-05-14 Apotex Inc. Zuclpomiphene salts and crystalline forms thereof
CA3098552A1 (en) 2019-11-14 2021-05-14 Apotex Inc. Processes for the preparation of zuclomiphene and intermediates thereof
CA3105944A1 (en) 2020-01-22 2021-07-22 Apotex Inc. Crystalline forms of zuclomiphene citrate

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT951631B (it) 1971-03-18 1973-07-10 Richardson Merrell Spa Composti utili per la separazione di isomeri ottici geometrici e strutturali e relativo procedimen to di sintesi
US4729999A (en) * 1984-10-12 1988-03-08 Bcm Technologies Antiestrogen therapy for symptoms of estrogen deficiency
US20040214898A1 (en) 2001-11-29 2004-10-28 Steiner Mitchell S. Methods for treating hot flashes
US20040213841A1 (en) * 2001-11-29 2004-10-28 Steiner Mitchell S Methods for treating hot flashes and gynecomastia
DE60230687D1 (de) * 2001-11-29 2009-02-12 Gtx Inc Verhinderung und Behandlung von durch Androgenmangel induzierter Osteoporose
US6762524B2 (en) * 2002-08-01 2004-07-13 Albert Six Magnetic drive system for a vehicle differential
ZA200706016B (en) * 2004-12-21 2008-12-31 Musc Found For Res Dev Compositions and methods for promoting wound healing and tissue regeneration
US8158828B2 (en) * 2005-11-28 2012-04-17 Gtx, Inc. Nuclear receptor binding agents
US8637706B2 (en) * 2005-11-28 2014-01-28 Gtx, Inc. Nuclear receptor binding agents
US20090215738A1 (en) * 2008-02-26 2009-08-27 Michael Charles Scally Prevention and treatment of an increase in cardiovascular risk, adverse cardiovascular events, infertility, and adverse psychological effects after androgen or gnrh analogue intake
RU2020120156A (ru) * 2014-07-24 2020-07-03 Эспен Парк Фармасьютикалз, Инк. Лечение приливов и потери костной ткани, вызванных андрогенной депривационной терапией с применением цис-кломифена

Also Published As

Publication number Publication date
IL249989B (en) 2022-03-01
PT3171866T (pt) 2020-10-21
JP2017522389A (ja) 2017-08-10
CN107072969A (zh) 2017-08-18
UA121971C2 (uk) 2020-08-25
US20170202788A1 (en) 2017-07-20
PL3171866T3 (pl) 2021-04-06
RU2017105837A3 (lt) 2019-03-11
US20180153829A1 (en) 2018-06-07
EP3171866A4 (en) 2017-12-27
CY1123861T1 (el) 2022-03-24
IL290004A (en) 2022-03-01
CN107072969B (zh) 2020-04-21
IL249989A0 (en) 2017-03-30
CN111346076A (zh) 2020-06-30
HRP20201726T1 (hr) 2021-01-08
US9913815B2 (en) 2018-03-13
RU2725086C2 (ru) 2020-06-29
DK3171866T3 (da) 2020-11-09
ES2828305T3 (es) 2021-05-26
US10463635B2 (en) 2019-11-05
EP3769756A1 (en) 2021-01-27
RU2017105837A (ru) 2018-08-30
JP6743001B2 (ja) 2020-08-19
WO2016014812A1 (en) 2016-01-28
AU2015292519A1 (en) 2017-02-02
US10758500B2 (en) 2020-09-01
MX2017000886A (es) 2017-08-10
EP3171866A1 (en) 2017-05-31
KR20230005415A (ko) 2023-01-09
AU2015292519B2 (en) 2020-09-03
HUE051442T2 (hu) 2021-03-01
KR20170040797A (ko) 2017-04-13
EP3171866B1 (en) 2020-08-19
RU2020120156A (ru) 2020-07-03
US20200085768A1 (en) 2020-03-19

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