DK3151859T3 - Virkningsfuld og effektiv kontrol af serumphosphat til optimal knogledannelse - Google Patents

Virkningsfuld og effektiv kontrol af serumphosphat til optimal knogledannelse Download PDF

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Publication number
DK3151859T3
DK3151859T3 DK15806501.1T DK15806501T DK3151859T3 DK 3151859 T3 DK3151859 T3 DK 3151859T3 DK 15806501 T DK15806501 T DK 15806501T DK 3151859 T3 DK3151859 T3 DK 3151859T3
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Denmark
Prior art keywords
effective
serumhosphat
bone formation
optimal bone
control
Prior art date
Application number
DK15806501.1T
Other languages
English (en)
Inventor
Emil Kakkis
Martin Javier San
Tomohiro Sudo
Original Assignee
Ultragenyx Pharmaceutical Inc
Kyowa Kirin Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ultragenyx Pharmaceutical Inc, Kyowa Kirin Co Ltd filed Critical Ultragenyx Pharmaceutical Inc
Application granted granted Critical
Publication of DK3151859T3 publication Critical patent/DK3151859T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/00113Growth factors
    • A61K39/001132Fibroblast growth factors [FGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK15806501.1T 2014-06-09 2015-05-29 Virkningsfuld og effektiv kontrol af serumphosphat til optimal knogledannelse DK3151859T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462009474P 2014-06-09 2014-06-09
PCT/US2015/033226 WO2015191312A1 (en) 2014-06-09 2015-05-29 The effective and efficient control of serum phosphate for optimal bone formation

Publications (1)

Publication Number Publication Date
DK3151859T3 true DK3151859T3 (da) 2021-02-15

Family

ID=54769049

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15806501.1T DK3151859T3 (da) 2014-06-09 2015-05-29 Virkningsfuld og effektiv kontrol af serumphosphat til optimal knogledannelse

Country Status (23)

Country Link
US (4) US10639360B2 (da)
EP (2) EP3151859B1 (da)
JP (2) JP6808493B2 (da)
KR (3) KR20170013993A (da)
CN (1) CN106604743A (da)
AR (1) AR100689A1 (da)
AU (1) AU2015275128C1 (da)
BR (2) BR122023023102A2 (da)
CA (1) CA2949234C (da)
CL (1) CL2016003179A1 (da)
CY (1) CY1124328T1 (da)
DK (1) DK3151859T3 (da)
ES (1) ES2851674T3 (da)
HR (1) HRP20210250T1 (da)
HU (1) HUE053271T2 (da)
LT (1) LT3151859T (da)
MX (2) MX2016016296A (da)
PE (1) PE20170248A1 (da)
PL (1) PL3151859T3 (da)
PT (1) PT3151859T (da)
RS (1) RS61443B1 (da)
SI (1) SI3151859T1 (da)
WO (1) WO2015191312A1 (da)

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EP1759001B1 (en) 2004-04-21 2011-04-13 Enobia Pharma Inc. Bone delivery conjugates and method of using same to target proteins to bone
CN106604743A (zh) 2014-06-09 2017-04-26 奥特吉尼克斯制药公司 用于最佳骨形成的血清磷酸盐的有效和高效控制
US10822596B2 (en) 2014-07-11 2020-11-03 Alexion Pharmaceuticals, Inc. Compositions and methods for treating craniosynostosis
MX2017007392A (es) 2014-12-05 2019-01-24 Alexion Pharma Inc Tratamiento de convulsiones con fosfatasa alcalina recombinante.
JP6868561B2 (ja) 2015-01-28 2021-05-12 アレクシオン ファーマシューティカルズ, インコーポレイテッド アルカリホスファターゼ欠損を有する被験者を治療する方法
AU2016308624B2 (en) 2015-08-17 2022-06-23 Alexion Pharmaceuticals, Inc. Manufacturing of alkaline phosphatases
JP6868617B2 (ja) 2015-09-28 2021-05-12 アレクシオン ファーマシューティカルズ, インコーポレイテッド 低ホスファターゼ血症の組織非特異的アルカリホスファターゼ(tnsalp)酵素補充療法に有効な投薬計画の特定
EP3368062A4 (en) 2015-10-30 2019-07-03 Alexion Pharmaceuticals, Inc. METHODS OF TREATING CRANIOSYNOSTOSIS IN A PATIENT
US11065306B2 (en) 2016-03-08 2021-07-20 Alexion Pharmaceuticals, Inc. Methods for treating hypophosphatasia in children
EP3436020A4 (en) * 2016-04-01 2019-12-25 Alexion Pharmaceuticals, Inc. METHOD FOR TREATING HYPOPHOSPHATASIE IN TEENS AND ADULTS
EP3436052A4 (en) 2016-04-01 2019-10-09 Alexion Pharmaceuticals, Inc. TREATMENT OF MUSCLE WEAKNESS USING ALKALINE PHOSPHATASES
US10988744B2 (en) 2016-06-06 2021-04-27 Alexion Pharmaceuticals, Inc. Method of producing alkaline phosphatase
US11116821B2 (en) 2016-08-18 2021-09-14 Alexion Pharmaceuticals, Inc. Methods for treating tracheobronchomalacia
CN106709662B (zh) * 2016-12-30 2021-07-02 山东鲁能软件技术有限公司 一种电力设备运行工况划分方法
EP3600383A4 (en) 2017-03-31 2020-10-28 Alexion Pharmaceuticals, Inc. METHODS FOR TREATMENT OF HYPOPHOSPHATASIA (HPP) IN ADULTS AND ADOLESCENTS
EP3773684A1 (en) 2018-03-30 2021-02-17 Alexion Pharmaceuticals, Inc. Manufacturing of glycoproteins
EP4291224A1 (en) 2021-02-12 2023-12-20 Alexion Pharmaceuticals, Inc. Alkaline phosphatase polypeptides and methods of use thereof

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CA2418215A1 (en) * 2000-07-19 2002-01-31 Advanced Research & Technology Institute Novel fibroblast growth factor (fgf23) and methods for use
DE60142239D1 (de) 2000-08-11 2010-07-08 Kyowa Hakko Kirin Co Ltd DEN PHOSPHORSÄURE-METABOLISMUS, DEN KALZIUM-METABOLISMUS, VERKALKUNG UND DEN VITAMIN D-METABOLISMUS KONTROLLIERENDE POLYPEPTIDE SOWIE FüR DIESE KODIERENDE DNA-MOLEKÜLE
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WO2012050673A1 (en) 2010-10-14 2012-04-19 Wisconsin Alumni Research Foundation Methods for the treatment of x-linked hypophosphatemia and related disorders
CN106604743A (zh) 2014-06-09 2017-04-26 奥特吉尼克斯制药公司 用于最佳骨形成的血清磷酸盐的有效和高效控制

Also Published As

Publication number Publication date
ES2851674T3 (es) 2021-09-08
US20220133871A1 (en) 2022-05-05
CN106604743A (zh) 2017-04-26
EP3151859B1 (en) 2020-11-25
US11202822B2 (en) 2021-12-21
US10639360B2 (en) 2020-05-05
MX2021003740A (es) 2021-05-27
US20240115683A1 (en) 2024-04-11
PL3151859T3 (pl) 2021-07-26
EP3151859A1 (en) 2017-04-12
EP3151859A4 (en) 2018-01-17
MX2016016296A (es) 2017-10-12
JP2017524656A (ja) 2017-08-31
AR100689A1 (es) 2016-10-26
CA2949234A1 (en) 2015-12-17
CY1124328T1 (el) 2022-07-22
BR112016028567A2 (pt) 2018-01-30
KR20170013993A (ko) 2017-02-07
AU2015275128A1 (en) 2016-12-08
SI3151859T1 (sl) 2021-06-30
WO2015191312A1 (en) 2015-12-17
KR20210099180A (ko) 2021-08-11
JP2021050226A (ja) 2021-04-01
AU2015275128B2 (en) 2019-10-31
PE20170248A1 (es) 2017-04-14
LT3151859T (lt) 2021-03-25
CL2016003179A1 (es) 2017-11-03
US20150353633A1 (en) 2015-12-10
BR122023023102A2 (pt) 2024-03-05
JP6993490B2 (ja) 2022-02-03
CA2949234C (en) 2022-03-22
HUE053271T2 (hu) 2021-06-28
HRP20210250T1 (hr) 2021-04-02
US11771748B2 (en) 2023-10-03
PT3151859T (pt) 2021-02-03
RS61443B1 (sr) 2021-03-31
AU2015275128C1 (en) 2020-02-13
JP6808493B2 (ja) 2021-01-06
US20200330575A1 (en) 2020-10-22
EP3845245A1 (en) 2021-07-07
KR20240093956A (ko) 2024-06-24

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