DK3169704T3 - Molekyler med specificitet for cd45 og cd79 - Google Patents

Molekyler med specificitet for cd45 og cd79 Download PDF

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Publication number
DK3169704T3
DK3169704T3 DK15738655.8T DK15738655T DK3169704T3 DK 3169704 T3 DK3169704 T3 DK 3169704T3 DK 15738655 T DK15738655 T DK 15738655T DK 3169704 T3 DK3169704 T3 DK 3169704T3
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molecules
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DK15738655.8T
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English (en)
Inventor
Helene Margaret Finney
Stephen Edward Rapecki
Michael John Wright
Kerry Tyson
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UCB Biopharma SRL
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Application filed by UCB Biopharma SRL filed Critical UCB Biopharma SRL
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Publication of DK3169704T3 publication Critical patent/DK3169704T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/289—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD45
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK15738655.8T 2014-07-16 2015-07-16 Molekyler med specificitet for cd45 og cd79 DK3169704T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1412659.3A GB201412659D0 (en) 2014-07-16 2014-07-16 Molecules
PCT/EP2015/066368 WO2016009029A1 (en) 2014-07-16 2015-07-16 Molecules with specificity for cd45 and cd79

Publications (1)

Publication Number Publication Date
DK3169704T3 true DK3169704T3 (da) 2020-10-26

Family

ID=51454240

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15738655.8T DK3169704T3 (da) 2014-07-16 2015-07-16 Molekyler med specificitet for cd45 og cd79

Country Status (25)

Country Link
US (2) US10774152B2 (da)
EP (1) EP3169704B1 (da)
JP (1) JP2017529061A (da)
KR (1) KR20170035930A (da)
CN (1) CN106661112A (da)
AU (1) AU2015289093A1 (da)
BR (1) BR112016030908A2 (da)
CA (1) CA2953275A1 (da)
CL (1) CL2017000111A1 (da)
CO (1) CO2017000300A2 (da)
CY (1) CY1123441T1 (da)
DK (1) DK3169704T3 (da)
ES (1) ES2823950T3 (da)
GB (1) GB201412659D0 (da)
HR (1) HRP20201503T1 (da)
HU (1) HUE052282T2 (da)
IL (1) IL249536A0 (da)
LT (1) LT3169704T (da)
MX (1) MX2016017271A (da)
PL (1) PL3169704T3 (da)
PT (1) PT3169704T (da)
RU (1) RU2747980C2 (da)
SG (1) SG11201610565XA (da)
SI (1) SI3169704T1 (da)
WO (1) WO2016009029A1 (da)

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US20230151108A1 (en) 2020-02-13 2023-05-18 UCB Biopharma SRL Bispecific antibodies against cd9 and cd137
US20230125234A1 (en) 2020-02-13 2023-04-27 UCB Biopharma SRL Anti cd44-ctla4 bispecific antibodies
WO2021160266A1 (en) 2020-02-13 2021-08-19 UCB Biopharma SRL Bispecific antibodies binding hvem and cd9
EP4103612A1 (en) 2020-02-13 2022-12-21 UCB Biopharma SRL Bispecific antibodies against cd9
US20230096030A1 (en) 2020-02-13 2023-03-30 UCB Biopharma SRL Bispecific antibodies against cd9 and cd7
CN115768463A (zh) 2020-02-21 2023-03-07 哈普恩治疗公司 Flt3结合蛋白及使用方法
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MX2016017271A (es) 2017-05-08
PT3169704T (pt) 2020-11-03
KR20170035930A (ko) 2017-03-31
SI3169704T1 (sl) 2020-11-30
US10774152B2 (en) 2020-09-15
SG11201610565XA (en) 2017-01-27
RU2017104813A (ru) 2018-08-17
LT3169704T (lt) 2020-11-10
EP3169704A1 (en) 2017-05-24
US20170204183A1 (en) 2017-07-20
CN106661112A (zh) 2017-05-10
CA2953275A1 (en) 2016-01-21
PL3169704T3 (pl) 2021-01-25
HRP20201503T1 (hr) 2020-12-25
RU2017104813A3 (da) 2018-12-25
ES2823950T3 (es) 2021-05-10
BR112016030908A2 (pt) 2018-01-16
EP3169704B1 (en) 2020-07-29
GB201412659D0 (en) 2014-08-27
IL249536A0 (en) 2017-02-28
JP2017529061A (ja) 2017-10-05
AU2015289093A1 (en) 2017-02-02
CL2017000111A1 (es) 2017-11-10
CY1123441T1 (el) 2021-12-31
WO2016009029A1 (en) 2016-01-21
HUE052282T2 (hu) 2021-04-28
CO2017000300A2 (es) 2017-04-10
RU2747980C2 (ru) 2021-05-18

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