DK3091029T3 - Anti-IL13-antistofformuleringer - Google Patents

Anti-IL13-antistofformuleringer Download PDF

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Publication number
DK3091029T3
DK3091029T3 DK16169916.0T DK16169916T DK3091029T3 DK 3091029 T3 DK3091029 T3 DK 3091029T3 DK 16169916 T DK16169916 T DK 16169916T DK 3091029 T3 DK3091029 T3 DK 3091029T3
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DK
Denmark
Prior art keywords
antibody formulations
antibody
formulations
Prior art date
Application number
DK16169916.0T
Other languages
English (en)
Inventor
Ajay Deshmukh
Joumana Zeid
Thomas M Scherer
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK3091029T3 publication Critical patent/DK3091029T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance
DK16169916.0T 2011-10-31 2012-10-30 Anti-IL13-antistofformuleringer DK3091029T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161553916P 2011-10-31 2011-10-31
EP12846324.7A EP2773662A4 (en) 2011-10-31 2012-10-30 ANTIBODY FORMULATIONS

Publications (1)

Publication Number Publication Date
DK3091029T3 true DK3091029T3 (da) 2023-01-30

Family

ID=48192677

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16169916.0T DK3091029T3 (da) 2011-10-31 2012-10-30 Anti-IL13-antistofformuleringer

Country Status (26)

Country Link
US (3) US10000562B2 (da)
EP (3) EP3091029B1 (da)
JP (4) JP6120452B2 (da)
KR (4) KR101994809B1 (da)
CN (4) CN104039826A (da)
AR (2) AR088579A1 (da)
AU (3) AU2012332767C1 (da)
CA (2) CA2849210C (da)
DK (1) DK3091029T3 (da)
ES (1) ES2936387T3 (da)
FI (1) FI3091029T3 (da)
HK (1) HK1201857A1 (da)
HR (1) HRP20230153T1 (da)
HU (1) HUE061728T2 (da)
IL (2) IL232053B (da)
LT (1) LT3091029T (da)
MX (2) MX363226B (da)
MY (2) MY197851A (da)
PL (1) PL3091029T3 (da)
PT (1) PT3091029T (da)
RS (1) RS63948B1 (da)
RU (1) RU2665810C2 (da)
SG (1) SG11201401903PA (da)
SI (1) SI3091029T1 (da)
WO (1) WO2013066866A1 (da)
ZA (2) ZA201401779B (da)

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AU2018232943B2 (en) 2020-07-23
AU2012332767A1 (en) 2014-04-10
EP2773662A4 (en) 2015-07-01
KR20170096212A (ko) 2017-08-23
JP2014532664A (ja) 2014-12-08
RU2665810C2 (ru) 2018-09-04
AU2018232943A1 (en) 2018-10-11
KR102259829B1 (ko) 2021-06-03
ZA201901490B (en) 2021-06-30
HRP20230153T1 (hr) 2023-03-31
AR124140A2 (es) 2023-02-15
MX363226B (es) 2019-03-15
JP6921148B2 (ja) 2021-08-18
KR20190077127A (ko) 2019-07-02
KR20140084078A (ko) 2014-07-04
CA3078979C (en) 2022-10-11
IL232053A0 (en) 2014-05-28
RU2014116070A (ru) 2015-12-10
CA3078979A1 (en) 2013-05-10
JP6120452B2 (ja) 2017-04-26
AU2012332767B2 (en) 2016-05-12
US20190002552A1 (en) 2019-01-03
US10947307B2 (en) 2021-03-16
CN108704132A (zh) 2018-10-26
JP6272950B2 (ja) 2018-01-31
JP2016193922A (ja) 2016-11-17
NZ622654A (en) 2017-01-27
MY197851A (en) 2023-07-20
CA2849210A1 (en) 2013-05-10
IL276234B (en) 2022-04-01
CN104039826A (zh) 2014-09-10
US20210155684A1 (en) 2021-05-27
CN109078182B (zh) 2022-08-12
IL232053B (en) 2020-08-31
IL276234A (en) 2020-09-30
EP4218937A2 (en) 2023-08-02
JP2019203002A (ja) 2019-11-28
MY187874A (en) 2021-10-26
US20140348855A1 (en) 2014-11-27
MX2019002979A (es) 2020-02-10
EP3091029B1 (en) 2022-12-28
CN116077644A (zh) 2023-05-09
RS63948B1 (sr) 2023-02-28
PT3091029T (pt) 2023-02-03
FI3091029T3 (fi) 2023-03-20
CA2849210C (en) 2020-07-14
AR088579A1 (es) 2014-06-18
US10000562B2 (en) 2018-06-19
ZA201401779B (en) 2019-07-31
HK1201857A1 (en) 2015-09-11
EP3091029A1 (en) 2016-11-09
JP2018048166A (ja) 2018-03-29
SG11201401903PA (en) 2014-05-29
EP4218937A3 (en) 2023-10-25
SI3091029T1 (sl) 2023-03-31
WO2013066866A1 (en) 2013-05-10
CN109078182A (zh) 2018-12-25
HUE061728T2 (hu) 2023-08-28
MX2014004992A (es) 2014-08-27
EP2773662A1 (en) 2014-09-10
LT3091029T (lt) 2023-02-27
KR20200065104A (ko) 2020-06-08
BR112014008864A2 (pt) 2018-08-07
AU2012332767C1 (en) 2017-02-02
AU2016210757A1 (en) 2016-08-25
PL3091029T3 (pl) 2023-04-11
KR101994809B1 (ko) 2019-07-01
ES2936387T3 (es) 2023-03-16

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