BR112014008864A2 - Formulações, artigo de manufatura, método de tratamento da asma, método de tratamento da fibrose pulmonar idiopática, método para a administração subcutânea de uma formulação e uso de uma formulação - Google Patents
Formulações, artigo de manufatura, método de tratamento da asma, método de tratamento da fibrose pulmonar idiopática, método para a administração subcutânea de uma formulação e uso de uma formulaçãoInfo
- Publication number
- BR112014008864A2 BR112014008864A2 BR112014008864-0A BR112014008864A BR112014008864A2 BR 112014008864 A2 BR112014008864 A2 BR 112014008864A2 BR 112014008864 A BR112014008864 A BR 112014008864A BR 112014008864 A2 BR112014008864 A2 BR 112014008864A2
- Authority
- BR
- Brazil
- Prior art keywords
- formulation
- treatment method
- formulations
- pulmonary fibrosis
- subcutaneous administration
- Prior art date
Links
- 238000000034 method Methods 0.000 title 3
- 239000000203 mixture Substances 0.000 title 3
- 238000009472 formulation Methods 0.000 title 2
- 201000009794 Idiopathic Pulmonary Fibrosis Diseases 0.000 title 1
- 208000006673 asthma Diseases 0.000 title 1
- 208000036971 interstitial lung disease 2 Diseases 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000007920 subcutaneous administration Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Anesthesiology (AREA)
- Mycology (AREA)
- Vascular Medicine (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161553916P | 2011-10-31 | 2011-10-31 | |
| US61/553,916 | 2011-10-31 | ||
| PCT/US2012/062572 WO2013066866A1 (en) | 2011-10-31 | 2012-10-30 | Antibody formulations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112014008864A2 true BR112014008864A2 (pt) | 2018-08-07 |
| BR112014008864B1 BR112014008864B1 (pt) | 2021-11-09 |
Family
ID=48192677
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014008864-0A BR112014008864B1 (pt) | 2011-10-31 | 2012-10-31 | Formulações, seu uso e artigo de manufatura |
Country Status (27)
| Country | Link |
|---|---|
| US (3) | US10000562B2 (pt) |
| EP (3) | EP2773662A4 (pt) |
| JP (4) | JP6120452B2 (pt) |
| KR (4) | KR102259829B1 (pt) |
| CN (4) | CN104039826A (pt) |
| AR (2) | AR088579A1 (pt) |
| AU (3) | AU2012332767C1 (pt) |
| BR (1) | BR112014008864B1 (pt) |
| CA (2) | CA3078979C (pt) |
| DK (1) | DK3091029T3 (pt) |
| ES (1) | ES2936387T3 (pt) |
| FI (1) | FI3091029T3 (pt) |
| HK (1) | HK1201857A1 (pt) |
| HR (1) | HRP20230153T1 (pt) |
| HU (1) | HUE061728T2 (pt) |
| IL (2) | IL232053B (pt) |
| LT (1) | LT3091029T (pt) |
| MX (2) | MX363226B (pt) |
| MY (2) | MY197851A (pt) |
| PL (1) | PL3091029T3 (pt) |
| PT (1) | PT3091029T (pt) |
| RS (1) | RS63948B1 (pt) |
| RU (1) | RU2665810C2 (pt) |
| SG (1) | SG11201401903PA (pt) |
| SI (1) | SI3091029T1 (pt) |
| WO (1) | WO2013066866A1 (pt) |
| ZA (2) | ZA201401779B (pt) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3578205A1 (en) | 2010-08-06 | 2019-12-11 | ModernaTX, Inc. | A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof |
| WO2012045082A2 (en) | 2010-10-01 | 2012-04-05 | Jason Schrum | Engineered nucleic acids and methods of use thereof |
| AU2012236099A1 (en) | 2011-03-31 | 2013-10-03 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
| JP6224581B2 (ja) | 2011-06-24 | 2017-11-01 | ケーシーアイ ライセンシング インコーポレイテッド | 組織固定要素を採用する減圧ドレッシング |
| US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| EP3682905B1 (en) | 2011-10-03 | 2021-12-01 | ModernaTX, Inc. | Modified nucleosides, nucleotides, and nucleic acids, and uses thereof |
| AU2012328530A1 (en) | 2011-10-28 | 2014-06-26 | Prothena Biosciences Limited | Humanized antibodies that recognize alpha-synuclein |
| AU2012332767C1 (en) * | 2011-10-31 | 2017-02-02 | Genentech, Inc. | Antibody formulations |
| DK2791160T3 (da) | 2011-12-16 | 2022-05-30 | Modernatx Inc | Modificerede mrna-sammensætninger |
| EP2807188B1 (en) | 2012-01-27 | 2019-09-11 | Prothena Biosciences Limited | Humanized antibodies that recognize alpha-synuclein |
| DE18200782T1 (de) | 2012-04-02 | 2021-10-21 | Modernatx, Inc. | Modifizierte polynukleotide zur herstellung von proteinen im zusammenhang mit erkrankungen beim menschen |
| US9878056B2 (en) | 2012-04-02 | 2018-01-30 | Modernatx, Inc. | Modified polynucleotides for the production of cosmetic proteins and peptides |
| US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
| UA118441C2 (uk) | 2012-10-08 | 2019-01-25 | Протена Біосаєнсиз Лімітед | Антитіло, що розпізнає альфа-синуклеїн |
| HRP20220607T1 (hr) | 2012-11-26 | 2022-06-24 | Modernatx, Inc. | Terminalno modificirana rna |
| US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
| US10513555B2 (en) | 2013-07-04 | 2019-12-24 | Prothena Biosciences Limited | Antibody formulations and methods |
| SG10201802525QA (en) * | 2013-09-13 | 2018-04-27 | Genentech Inc | Methods and compositions comprising purified recombinant polypeptides |
| BR112016004437A2 (pt) | 2013-09-13 | 2017-10-17 | Genentech Inc | métodos de imunoteste e de seleção de linhagem de células, anticorpos e kit |
| WO2015048744A2 (en) | 2013-09-30 | 2015-04-02 | Moderna Therapeutics, Inc. | Polynucleotides encoding immune modulating polypeptides |
| EP3052521A1 (en) | 2013-10-03 | 2016-08-10 | Moderna Therapeutics, Inc. | Polynucleotides encoding low density lipoprotein receptor |
| WO2015079977A1 (ja) * | 2013-11-26 | 2015-06-04 | シャープ株式会社 | 抗体分離方法、抗体評価方法、医薬の評価方法、及び、抗体の２次元電気泳動用キット |
| CA2944402A1 (en) | 2014-04-08 | 2015-10-15 | Prothena Biosciences Limited | Blood-brain barrier shuttles containing antibodies recognizing alpha-synuclein |
| US11357857B2 (en) | 2014-06-20 | 2022-06-14 | Comera Life Sciences, Inc. | Excipient compounds for protein processing |
| US20160074515A1 (en) | 2014-06-20 | 2016-03-17 | Reform Biologics, Llc | Viscosity-reducing excipient compounds for protein formulations |
| US10478498B2 (en) | 2014-06-20 | 2019-11-19 | Reform Biologics, Llc | Excipient compounds for biopolymer formulations |
| ES2788999T3 (es) | 2014-12-23 | 2020-10-23 | Merz Pharma Gmbh & Co Kgaa | Envase prellenado de toxina botulínica |
| RU2752785C2 (ru) * | 2016-09-23 | 2021-08-04 | Дженентек, Инк. | Применение антагонистов il-13 для лечения атопического дерматита |
| CN110167531A (zh) * | 2017-01-11 | 2019-08-23 | 赛特瑞恩股份有限公司 | 稳定的液体调配物 |
| JP2019048091A (ja) * | 2018-10-23 | 2019-03-28 | ニプロ株式会社 | デクスメデトミジン注射液を充填したプレフィルドシリンジ |
| JP7101418B2 (ja) * | 2019-01-02 | 2022-07-15 | エム アンド ジェイ サイエンティフィック エルエルシー | 光散乱検出器及び光散乱検出器のための方法 |
| US11634485B2 (en) | 2019-02-18 | 2023-04-25 | Eli Lilly And Company | Therapeutic antibody formulation |
| KR20220122993A (ko) * | 2019-11-26 | 2022-09-05 | 코메라 라이프 사이언시스, 인코포레이티드 | 바이오폴리머 제형을 위한 부형제 화합물 |
| MX2023004533A (es) * | 2020-10-22 | 2023-07-05 | Allakos Inc | Formulaciones de anticuerpos anti-siglec-8. |
| AU2022309469A1 (en) | 2021-07-16 | 2024-02-01 | Dermira, Inc. | Il-13 antibodies for the treatment of atopic dermatitis |
| TW202323291A (zh) | 2021-08-13 | 2023-06-16 | 美商德米拉股份有限公司 | 用於治療異位性皮膚炎之il-13抗體 |
| MX2024003183A (es) | 2021-09-15 | 2024-03-26 | Dermira Inc | Inhibidores de il-13 para el tratamiento del prurigo nodular. |
| WO2023215769A1 (en) | 2022-05-05 | 2023-11-09 | Dermira, Inc. | Il-13 antibodies for the treatment of atopic dermatitis |
| WO2024186796A1 (en) | 2023-03-08 | 2024-09-12 | Dermira, Inc. | Il-13 antibodies for the treatment of atopic dermatitis |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| WO1988001213A1 (en) | 1986-08-18 | 1988-02-25 | Clinical Technologies Associates, Inc. | Delivery systems for pharmacological agents |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US5959177A (en) | 1989-10-27 | 1999-09-28 | The Scripps Research Institute | Transgenic plants expressing assembled secretory antibodies |
| DE69133566T2 (de) | 1990-01-12 | 2007-12-06 | Amgen Fremont Inc. | Bildung von xenogenen Antikörpern |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| EP0814159B1 (en) | 1990-08-29 | 2005-07-27 | GenPharm International, Inc. | Transgenic mice capable of producing heterologous antibodies |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US7018809B1 (en) | 1991-09-19 | 2006-03-28 | Genentech, Inc. | Expression of functional antibody fragments |
| DE69329295T2 (de) | 1992-12-02 | 2001-03-15 | Alkermes Controlled Therapeutics, Inc. | Wachstumhormon enthaltende mikrosphaeren mit kontrollierter freisetzung |
| PT779806E (pt) | 1994-09-09 | 2001-02-28 | Takeda Chemical Industries Ltd | Preparacao de libertacao sustentada contendo um sal metalico de um peptido |
| US5789199A (en) | 1994-11-03 | 1998-08-04 | Genentech, Inc. | Process for bacterial production of polypeptides |
| US5840523A (en) | 1995-03-01 | 1998-11-24 | Genetech, Inc. | Methods and compositions for secretion of heterologous polypeptides |
| ATE390933T1 (de) | 1995-04-27 | 2008-04-15 | Amgen Fremont Inc | Aus immunisierten xenomäusen stammende menschliche antikörper gegen il-8 |
| AU2466895A (en) | 1995-04-28 | 1996-11-18 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| AU708756B2 (en) | 1995-06-07 | 1999-08-12 | Alkermes Controlled Therapeutics, Inc. | Composition for sustained release of human growth hormone |
| ZA965368B (en) | 1995-07-14 | 1997-01-14 | Novo Nordisk As | A pharmaceutical formulation |
| AU5702298A (en) | 1996-12-03 | 1998-06-29 | Abgenix, Inc. | Transgenic mammals having human Ig loci including plural VH and VK regions nd antibodies produced therefrom |
| US6040498A (en) | 1998-08-11 | 2000-03-21 | North Caroline State University | Genetically engineered duckweed |
| US7125978B1 (en) | 1999-10-04 | 2006-10-24 | Medicago Inc. | Promoter for regulating expression of foreign genes |
| DE60022369T2 (de) | 1999-10-04 | 2006-05-18 | Medicago Inc., Sainte Foy | Verfahren zur regulation der transkription von fremden genen in gegenwart von stickstoff |
| US7288390B2 (en) | 2000-08-07 | 2007-10-30 | Centocor, Inc. | Anti-dual integrin antibodies, compositions, methods and uses |
| SI1324776T2 (en) | 2000-10-12 | 2018-06-29 | Genentech, Inc. | Concentrated protein formulations with reduced viscosity |
| MXPA04003901A (es) * | 2001-11-07 | 2004-07-08 | Cytos Biotechnology Ag | Disposiciones de antigenos para el tratamiento de enfermedades eosinofilicas alergicas. |
| US7132100B2 (en) | 2002-06-14 | 2006-11-07 | Medimmune, Inc. | Stabilized liquid anti-RSV antibody formulations |
| US7425618B2 (en) | 2002-06-14 | 2008-09-16 | Medimmune, Inc. | Stabilized anti-respiratory syncytial virus (RSV) antibody formulations |
| PL213501B1 (pl) * | 2003-02-28 | 2013-03-29 | Ares Trading Sa | Wodny preparat bialka wiazacego czynnik martwicy nowotworu i sposób jego wytwarzania |
| US20050158303A1 (en) | 2003-04-04 | 2005-07-21 | Genentech, Inc. | Methods of treating IgE-mediated disorders comprising the administration of high concentration anti-IgE antibody formulations |
| AU2004229335C1 (en) | 2003-04-04 | 2010-06-17 | Genentech, Inc. | High concentration antibody and protein formulations |
| AR045614A1 (es) * | 2003-09-10 | 2005-11-02 | Hoffmann La Roche | Anticuerpos contra el recepctor de la interleuquina- 1 y los usos de los mismos |
| HUE049161T2 (hu) | 2003-12-23 | 2020-09-28 | Genentech Inc | Új anti-IL13 antitestek és alkalmazásaik |
| JO3000B1 (ar) * | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| US20080248048A1 (en) | 2005-09-30 | 2008-10-09 | Astrazeneca Ab | Interleukin-13 Antibody Composition |
| CA2625664C (en) * | 2005-10-21 | 2016-01-05 | Novartis Ag | Human antibodies against il13 and therapeutic uses |
| AU2006330858A1 (en) * | 2005-12-21 | 2007-07-05 | Wyeth | Protein formulations with reduced viscosity and uses thereof |
| TWI395754B (zh) * | 2006-04-24 | 2013-05-11 | Amgen Inc | 人類化之ｃ-ｋｉｔ抗體 |
| MX2009007406A (es) * | 2007-01-09 | 2010-01-25 | Wyeth Corp | Formulaciones de anticuerpo anti-il-13 y usos de las mismas. |
| CA2676881C (en) * | 2008-09-30 | 2017-04-25 | Wyeth | Peripheral opioid receptor antagonists and uses thereof |
| BRPI0922806B8 (pt) * | 2008-12-03 | 2021-05-25 | Astellas Deutschland Gmbh | composição farmacêutica oral compreendendo bendamustina |
| SG174258A1 (en) * | 2009-03-06 | 2011-10-28 | Genentech Inc | Antibody formulation |
| MX2012009755A (es) | 2010-02-26 | 2012-09-12 | Novo Nordisk As | Composiciones que contienen anticuerpo estable. |
| CN106983862A (zh) * | 2010-03-22 | 2017-07-28 | 弗·哈夫曼-拉罗切有限公司 | 对于稳定含有蛋白质的制剂有用的组合物和方法 |
| MX2012012743A (es) | 2010-05-03 | 2012-11-23 | Genentech Inc | Composiciones y metodos utiles para reducir la viscosidad de formulaciones que contienen proteina. |
| CA2831572C (en) | 2011-05-02 | 2019-11-26 | Immunomedics, Inc. | Ultrafiltration concentration of allotype selected antibodies for small-volume administration |
| AU2012332767C1 (en) * | 2011-10-31 | 2017-02-02 | Genentech, Inc. | Antibody formulations |
-
2012
- 2012-10-30 AU AU2012332767A patent/AU2012332767C1/en active Active
- 2012-10-30 FI FIEP16169916.0T patent/FI3091029T3/fi active
- 2012-10-30 MX MX2014004992A patent/MX363226B/es unknown
- 2012-10-30 PT PT161699160T patent/PT3091029T/pt unknown
- 2012-10-30 PL PL16169916.0T patent/PL3091029T3/pl unknown
- 2012-10-30 HR HRP20230153TT patent/HRP20230153T1/hr unknown
- 2012-10-30 KR KR1020207015572A patent/KR102259829B1/ko active IP Right Grant
- 2012-10-30 DK DK16169916.0T patent/DK3091029T3/da active
- 2012-10-30 SI SI201232018T patent/SI3091029T1/sl unknown
- 2012-10-30 CN CN201280053245.XA patent/CN104039826A/zh active Pending
- 2012-10-30 RU RU2014116070A patent/RU2665810C2/ru active
- 2012-10-30 CA CA3078979A patent/CA3078979C/en active Active
- 2012-10-30 LT LTEP16169916.0T patent/LT3091029T/lt unknown
- 2012-10-30 MY MYPI2018001912A patent/MY197851A/en unknown
- 2012-10-30 ES ES16169916T patent/ES2936387T3/es active Active
- 2012-10-30 KR KR1020197018310A patent/KR20190077127A/ko not_active Application Discontinuation
- 2012-10-30 CN CN201810964731.6A patent/CN109078182B/zh active Active
- 2012-10-30 RS RS20230095A patent/RS63948B1/sr unknown
- 2012-10-30 CN CN202210876554.2A patent/CN116077644A/zh active Pending
- 2012-10-30 HU HUE16169916A patent/HUE061728T2/hu unknown
- 2012-10-30 CN CN201810964732.0A patent/CN108704132A/zh active Pending
- 2012-10-30 KR KR20147011246A patent/KR20140084078A/ko active Search and Examination
- 2012-10-30 SG SG11201401903PA patent/SG11201401903PA/en unknown
- 2012-10-30 KR KR1020177022308A patent/KR101994809B1/ko active IP Right Grant
- 2012-10-30 EP EP12846324.7A patent/EP2773662A4/en not_active Withdrawn
- 2012-10-30 AR ARP120104056 patent/AR088579A1/es not_active Application Discontinuation
- 2012-10-30 MY MYPI2014001225A patent/MY187874A/en unknown
- 2012-10-30 CA CA2849210A patent/CA2849210C/en active Active
- 2012-10-30 EP EP16169916.0A patent/EP3091029B1/en active Active
- 2012-10-30 EP EP22208284.4A patent/EP4218937A3/en active Pending
- 2012-10-30 WO PCT/US2012/062572 patent/WO2013066866A1/en active Application Filing
- 2012-10-30 JP JP2014539136A patent/JP6120452B2/ja active Active
- 2012-10-31 BR BR112014008864-0A patent/BR112014008864B1/pt active IP Right Grant
-
2014
- 2014-03-11 ZA ZA2014/01779A patent/ZA201401779B/en unknown
- 2014-04-10 IL IL232053A patent/IL232053B/en active IP Right Grant
- 2014-04-23 US US14/259,882 patent/US10000562B2/en active Active
- 2014-04-24 MX MX2019002979A patent/MX2019002979A/es unknown
-
2015
- 2015-03-09 HK HK15102358.5A patent/HK1201857A1/xx unknown
-
2016
- 2016-06-08 JP JP2016114267A patent/JP6272950B2/ja active Active
- 2016-08-05 AU AU2016210757A patent/AU2016210757A1/en not_active Abandoned
-
2017
- 2017-10-18 JP JP2017202159A patent/JP2018048166A/ja not_active Withdrawn
-
2018
- 2018-06-07 US US16/002,932 patent/US10947307B2/en active Active
- 2018-09-19 AU AU2018232943A patent/AU2018232943B2/en active Active
-
2019
- 2019-03-11 ZA ZA2019/01490A patent/ZA201901490B/en unknown
- 2019-06-25 JP JP2019116979A patent/JP6921148B2/ja active Active
-
2020
- 2020-07-22 IL IL276234A patent/IL276234B/en unknown
-
2021
- 2021-02-04 US US17/167,754 patent/US20210155684A1/en active Pending
- 2021-11-24 AR ARP210103246A patent/AR124140A2/es unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112014008864A2 (pt) | Formulações, artigo de manufatura, método de tratamento da asma, método de tratamento da fibrose pulmonar idiopática, método para a administração subcutânea de uma formulação e uso de uma formulação | |
| BR112013033803A2 (pt) | formulação integrada com microagulha, e, método para administrar uma substância | |
| BR112014012005A2 (pt) | composições, métodos, formulação farmacêutica e artigo | |
| BR112013030472A2 (pt) | formulação farmacêutica, artigo de fabricação e método | |
| BR112013021274A2 (pt) | composição cosmética botânica bioativa, formulação cosmética botânica bioativa, e método para preparar uma composição cosmética botânica bioativa | |
| IL238064B (en) | A formulation containing smallpox virus, a method for preparing a freeze-dried formulation and their uses | |
| GB2502029B (en) | Cosmetic or pharmaceutical formulation comprising hyaluronate crosspolymer and one or more of; azelaic acid, or derivative, and natural oils | |
| BR112015004231A2 (pt) | composição inalável, recipiente pressurizado cigarro simulado, método para a fabricação de uma composição, e, uso da composição | |
| BR112014002986A2 (pt) | composição sob a forma de uma solução injetável, e formulação de dose única | |
| ZA201408990B (en) | Pharmaceutical compositions comprising rifaximin and amino acids, preparation method and use thereof | |
| IL231270A (en) | Kynurenine-3-monooxygenase inhibitors, pharmaceuticals containing them and methods of use | |
| DK2529756T3 (da) | Risperidon- og/eller paliperidon-implantatformulering | |
| BRPI0921429A2 (pt) | formulação farmacêutica liofilizada estável, e, método para preparar um fator liofilizado estável | |
| GB2505860B (en) | Aripiprazole medicament formulation and preparation method therefor | |
| IL230463A (en) | Benzamides, their preparation and their pharmaceutical preparations | |
| BR112014026564A2 (pt) | formulação, uso de uma formulação, e, processo para a preparação de uma formulação | |
| ZA201400188B (en) | Substituted cinnamamide derivative, preparation method and use thereof | |
| BR112013015085A2 (pt) | composição farmacêutica, método para preparar uma composição, e, uso de composição | |
| EP2786982A4 (en) | AMINO-PROPYLENE-GLYCOL DERIVATIVES, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | |
| EP2818172A4 (en) | TLR4 MEDIUM, TISSUE HOMEOSTAT, HEPATOCYTE GROWTH FACTOR INDUCTOR, TISSUE-DISAPPEARING AGENT, AND SIRTUINE INDUCTOR WITH HYALURONIC ACID FRAGMENTS AS ACTIVE AGENTS THEREOF | |
| BR112014031513A2 (pt) | composição alimentícia concentrada, processo para preparar uma composição alimentícia concentrada e uso da composição | |
| BR112013017267A2 (pt) | formulação de lipossomas, suspensão e composição farmacêutica | |
| HK1188791A1 (zh) | 新型八氫噻吩並喹啉衍生物、包含所述衍生物的藥物組合物及它們的用途 | |
| EP2781512A4 (en) | OXADIAZOLE COMPOUND AND PROCESS FOR PREPARING THE SAME, PHARMACEUTICAL COMPOSITION AND USE THEREOF | |
| SG10201604468QA (en) | Shk-based pharmaceutical compositions and methods of manufacturing and using the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NAO 10196/2001, QUE MODIFICOU A LEI NAO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUAANCIA PRA VIA DA ANVISA. CONSIDERANDO A APROVAA AO DOS TERMOS DO PARECER NAO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NAO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDAANCIAS CABA-VEIS. |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 31/10/2012, OBSERVADAS AS CONDICOES LEGAIS. |