DK2924053T3 - Glycosyleret linker, forbindelse, der indeholder glycosyleret linker-del og fysiologisk aktiv stofdel eller salt deraf, og fremgangsmåder til fremstilling af forbindelsen eller saltet deraf - Google Patents
Glycosyleret linker, forbindelse, der indeholder glycosyleret linker-del og fysiologisk aktiv stofdel eller salt deraf, og fremgangsmåder til fremstilling af forbindelsen eller saltet deraf Download PDFInfo
- Publication number
- DK2924053T3 DK2924053T3 DK13857593.1T DK13857593T DK2924053T3 DK 2924053 T3 DK2924053 T3 DK 2924053T3 DK 13857593 T DK13857593 T DK 13857593T DK 2924053 T3 DK2924053 T3 DK 2924053T3
- Authority
- DK
- Denmark
- Prior art keywords
- links
- glycosyled
- glycosylated
- salts
- preparation
- Prior art date
Links
- 239000013543 active substance Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
- C07K17/02—Peptides being immobilised on, or in, an organic carrier
- C07K17/10—Peptides being immobilised on, or in, an organic carrier the carrier being a carbohydrate
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
- C08H1/00—Macromolecular products derived from proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
- A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Inorganic Chemistry (AREA)
- Toxicology (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012256947 | 2012-11-22 | ||
| PCT/JP2013/079408 WO2014080730A1 (ja) | 2012-11-22 | 2013-10-30 | 糖鎖付加リンカー、糖鎖付加リンカー部分と生理活性物質部分とを含む化合物またはその塩、及びそれらの製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2924053T3 true DK2924053T3 (da) | 2020-12-14 |
Family
ID=50775917
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13857593.1T DK2924053T3 (da) | 2012-11-22 | 2013-10-30 | Glycosyleret linker, forbindelse, der indeholder glycosyleret linker-del og fysiologisk aktiv stofdel eller salt deraf, og fremgangsmåder til fremstilling af forbindelsen eller saltet deraf |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9708413B2 (da) |
| EP (1) | EP2924053B1 (da) |
| JP (1) | JP6211533B2 (da) |
| KR (1) | KR102227918B1 (da) |
| CN (1) | CN104918962B (da) |
| DK (1) | DK2924053T3 (da) |
| TW (1) | TWI634127B (da) |
| WO (1) | WO2014080730A1 (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI618697B (zh) | 2015-11-03 | 2018-03-21 | 財團法人工業技術研究院 | 化合物、連接子－藥物、及配體－藥物耦合體 |
| EP3770180A4 (en) * | 2018-03-22 | 2021-12-22 | Mochida Pharmaceutical Co., Ltd. | ALGIC ACID DERIVATIVE BONDED TO A NON-STEROIDAL ANTI-INFLAMMATORY COMPOUND |
| JP7437578B2 (ja) * | 2019-03-20 | 2024-02-26 | 国立大学法人東北大学 | 新規オピオイドペプチド、その糖鎖付加体及びそれらを含む医薬組成物 |
| CN113501889A (zh) * | 2021-07-06 | 2021-10-15 | 郑州大学 | 一种三七多糖阳离子衍生物的制备方法及其应用 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0778081B2 (ja) * | 1990-07-19 | 1995-08-23 | 静岡大学長 | 機能化高分子の合成方法 |
| JP2604930B2 (ja) * | 1990-12-14 | 1997-04-30 | 株式会社ディ・ディ・エス研究所 | ヒアルロン酸およびコンドロイチン誘導体 |
| JP2527885B2 (ja) * | 1992-09-02 | 1996-08-28 | 株式会社ディ・ディ・エス研究所 | ヘパリン誘導体 |
| ATE199908T1 (de) * | 1996-12-16 | 2001-04-15 | Nederlanden Staat | Verfahren zur kupplung von polysacchariden und proteinen |
| JP2001302695A (ja) | 2000-04-20 | 2001-10-31 | Asahi Kasei Corp | Ｇｌｎ結合型糖鎖付加カルシトニン誘導体 |
| US6441293B1 (en) | 2000-04-28 | 2002-08-27 | Labarbera Anthony | System for generating percussion sounds from stringed instruments |
| CA2451971C (en) | 2001-06-19 | 2010-09-07 | Otsuka Chemical Co., Ltd. | Process for producing sugar chain asparagine derivative |
| US20030096299A1 (en) | 2001-07-09 | 2003-05-22 | Valerie Wittamer | Natural ligand of G protein coupled receptor ChemR23 and uses thereof |
| US7943763B2 (en) | 2002-07-05 | 2011-05-17 | Otsuka Chemical Holdings Co., Ltd. | Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides |
| TWI335920B (en) | 2002-12-24 | 2011-01-11 | Yasuhiro Kajihara | Sugar chain asparagine derivatives, sugar chain asparagine and sugar chain and manufacture thereof |
| EP1577324B1 (en) | 2002-12-26 | 2014-08-13 | Yasuhiro Kajihara | Three-branched sugar-chain asparagine derivatives, the sugar-chain asparagines, the sugar chains, and processes for producing these |
| CA2514337C (en) | 2003-02-04 | 2010-07-13 | Otsuka Chemical Co., Ltd. | Process for producing sugar chain asparagine derivative |
| CA2521784C (en) | 2003-04-08 | 2012-03-27 | Yeda Research And Development Co. Ltd. | Reversible pegylated drugs |
| JP4555823B2 (ja) | 2003-07-11 | 2010-10-06 | セラヴァンス， インコーポレーテッド | 架橋されたグリコペプチド−セファロスポリン抗生物質 |
| JPWO2005007694A1 (ja) | 2003-07-16 | 2007-09-20 | 株式会社グリーンペプタイド | ＨＥＲ２／ｎｅｕペプチドおよびその治療上の用途 |
| CA2533849C (en) | 2003-07-28 | 2013-07-02 | Otsuka Chemical Co., Ltd. | Aminated complex-type sugar chain derivatives and process for the production thereof |
| JP2007501870A (ja) * | 2003-08-08 | 2007-02-01 | フレゼニウス・カビ・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | ヒドロキシアルキルデンプンとｇ−ｃｓｆの複合体 |
| CN1832762B (zh) * | 2003-08-08 | 2012-09-05 | 弗雷泽纽斯卡比德国有限公司 | 羟烷基淀粉与g-csf的偶联物 |
| CN1310898C (zh) | 2004-01-19 | 2007-04-18 | 中国人民解放军军事医学科学院毒物药物研究所 | 紫杉醇水溶性衍生物 |
| MXPA06010764A (es) | 2004-03-23 | 2006-12-15 | Amgen Inc | Metodos y composiciones de proteinas quimicamente modificadas. |
| JPWO2005095331A1 (ja) | 2004-03-31 | 2008-02-21 | 塩野義製薬株式会社 | 糖鎖−ペプチド結合剤 |
| TW200643033A (en) * | 2005-03-08 | 2006-12-16 | Chugai Pharmaceutical Co Ltd | Conjugate of water-soluble modified hyaluronic acid and glp-1 analogue |
| TWI342880B (en) | 2005-07-19 | 2011-06-01 | Otsuka Chemical Co Ltd | Method for producing sugar chain derivatives, and sugar chain derivatives |
| CA2696615A1 (en) * | 2007-06-19 | 2008-12-24 | Otsuka Chemical Co., Ltd. | Oligosaccharide chain added glp-1 peptide |
| ES2904673T3 (es) * | 2008-02-01 | 2022-04-05 | Ascendis Pharma As | Profármaco que comprende un conjugado de fármaco-enlazador. |
| JP2009242372A (ja) | 2008-03-11 | 2009-10-22 | Yokohama City Univ | 均一な糖鎖構造を有するエリスロポエチン誘導体 |
| RU2543157C2 (ru) | 2008-06-17 | 2015-02-27 | Глитек,Инк. | Гликозилированный пептид glp-1 |
| CA2734124C (en) | 2008-08-19 | 2018-06-05 | Otsuka Chemical Co., Ltd. | Glycoprotein production method and screening method |
| JP2010229093A (ja) | 2009-03-27 | 2010-10-14 | Banyu Pharmaceut Co Ltd | 新規ＣｈｅｍｅｒｉｎＲアゴニスト |
| US20120264684A1 (en) * | 2009-10-30 | 2012-10-18 | Yasuhiro Kajihara | Glycosylated Form of Antigenic GLP-1 Analogue |
-
2013
- 2013-10-30 DK DK13857593.1T patent/DK2924053T3/da active
- 2013-10-30 US US14/646,295 patent/US9708413B2/en active Active
- 2013-10-30 KR KR1020157015751A patent/KR102227918B1/ko active IP Right Grant
- 2013-10-30 EP EP13857593.1A patent/EP2924053B1/en active Active
- 2013-10-30 JP JP2014548498A patent/JP6211533B2/ja active Active
- 2013-10-30 WO PCT/JP2013/079408 patent/WO2014080730A1/ja active Application Filing
- 2013-10-30 CN CN201380070699.2A patent/CN104918962B/zh active Active
- 2013-11-20 TW TW102142224A patent/TWI634127B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| TW201427999A (zh) | 2014-07-16 |
| US20150299337A1 (en) | 2015-10-22 |
| US9708413B2 (en) | 2017-07-18 |
| KR20150102003A (ko) | 2015-09-04 |
| KR102227918B1 (ko) | 2021-03-15 |
| JPWO2014080730A1 (ja) | 2017-01-05 |
| WO2014080730A1 (ja) | 2014-05-30 |
| JP6211533B2 (ja) | 2017-10-11 |
| CN104918962B (zh) | 2017-12-19 |
| TWI634127B (zh) | 2018-09-01 |
| EP2924053B1 (en) | 2020-11-11 |
| EP2924053A4 (en) | 2016-08-24 |
| CN104918962A (zh) | 2015-09-16 |
| EP2924053A1 (en) | 2015-09-30 |
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| DK2924053T3 (da) | Glycosyleret linker, forbindelse, der indeholder glycosyleret linker-del og fysiologisk aktiv stofdel eller salt deraf, og fremgangsmåder til fremstilling af forbindelsen eller saltet deraf | |
| DK2871184T3 (da) | Benzodioxolderivat og fremgangsmåde til fremstilling og anvendelse deraf | |
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