DK2909225T3 - Fremgangsmåde til oprensning af abirateron-acetat - Google Patents

Fremgangsmåde til oprensning af abirateron-acetat

Info

Publication number
DK2909225T3
DK2909225T3 DK13789206.3T DK13789206T DK2909225T3 DK 2909225 T3 DK2909225 T3 DK 2909225T3 DK 13789206 T DK13789206 T DK 13789206T DK 2909225 T3 DK2909225 T3 DK 2909225T3
Authority
DK
Denmark
Prior art keywords
abiraterone acetate
purifying
purifying abiraterone
acetate
abiraterone
Prior art date
Application number
DK13789206.3T
Other languages
English (en)
Inventor
Marco Alpegiani
Tania Cristiano
Eugenio Cucchetti
Original Assignee
Olon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olon Spa filed Critical Olon Spa
Application granted granted Critical
Publication of DK2909225T3 publication Critical patent/DK2909225T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/006Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32Bonded phase chromatography
    • B01D15/325Reversed phase
    • B01D15/327Reversed phase with hydrophobic interaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
DK13789206.3T 2012-10-22 2013-10-21 Fremgangsmåde til oprensning af abirateron-acetat DK2909225T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001788A ITMI20121788A1 (it) 2012-10-22 2012-10-22 Procedimento per la purificazione di abiraterone acetato
PCT/EP2013/071930 WO2014064032A1 (en) 2012-10-22 2013-10-21 Process for the purification of abiraterone acetate

Publications (1)

Publication Number Publication Date
DK2909225T3 true DK2909225T3 (da) 2017-01-02

Family

ID=47425221

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13789206.3T DK2909225T3 (da) 2012-10-22 2013-10-21 Fremgangsmåde til oprensning af abirateron-acetat

Country Status (12)

Country Link
US (1) US9340571B2 (da)
EP (1) EP2909225B1 (da)
JP (1) JP2015535223A (da)
KR (1) KR20150079614A (da)
AU (1) AU2013336781A1 (da)
BR (1) BR112015008855A2 (da)
CA (1) CA2888826A1 (da)
DK (1) DK2909225T3 (da)
ES (1) ES2596245T3 (da)
IL (1) IL238386A (da)
IT (1) ITMI20121788A1 (da)
WO (1) WO2014064032A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014071983A1 (en) * 2012-11-09 2014-05-15 Synthon Bv Process for making the 17-triflate intermediate of abiraterone-3-acetate
CZ2014475A3 (cs) * 2014-07-09 2016-01-20 Zentiva, K.S. Způsob přípravy Abirateron acetátu o vysoké čistotě aplikovatelný v průmyslovém měřítku
CN104109185B (zh) * 2014-08-06 2016-05-18 亿腾药业(泰州)有限公司 一种醋酸阿比特龙的制备方法
CN104447934B (zh) * 2014-12-08 2017-03-15 深圳科兴生物工程有限公司 一种醋酸阿比特龙的纯化方法
KR102363026B1 (ko) 2019-12-26 2022-02-16 보령제약 주식회사 아비라테론 아세테이트 또는 이의 약제학적으로 허용 가능한 염을 포함하는 전립선암 예방 또는 치료용 약학적 조성물
CN112125942B (zh) * 2020-09-28 2021-12-14 湖南新合新生物医药有限公司 醋酸阿比特龙及其中间体的合成方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0733395B2 (ja) * 1987-06-19 1995-04-12 武田薬品工業株式会社 抗生物質tan−928およびその製造法
JPH05194585A (ja) * 1991-03-13 1993-08-03 Kyowa Hakko Kogyo Co Ltd 化合物uca1064−b
JPH0576387A (ja) * 1991-07-22 1993-03-30 Snow Brand Milk Prod Co Ltd 14α− ヒドロキシ−4− アンドロステン−3,6,17−トリオンの新規製造方法
GB2265624B (en) 1992-03-31 1995-04-19 British Tech Group 17-substituted steroids useful in cancer treatment
JPH06225793A (ja) * 1992-11-27 1994-08-16 Nippon Kayaku Co Ltd 6β,14α−ジヒドロキシ−4−アンドロステン−3,17−ジオンの新規製造法
SG49321A1 (en) 1993-09-30 1998-05-18 British Tech Group Synthesis of 17-(3-pyridyl) steroids
WO1995018142A1 (en) * 1993-12-29 1995-07-06 Fujisawa Pharmaceutical Co., Ltd. Wf15604 substances
JPH08269085A (ja) * 1995-03-30 1996-10-15 Sankyo Co Ltd 新規スキャララン誘導体
JPH10245393A (ja) * 1997-02-28 1998-09-14 Shiseido Co Ltd トリテルペン類を含有する組成物
JP2001322934A (ja) * 2000-05-11 2001-11-20 Saraya Kk 抗酸化作用を有する羅漢果配糖体を含有する抗酸化組成物
JP4456321B2 (ja) * 2002-07-12 2010-04-28 株式会社ファンケル リパーゼ阻害剤
US20050143464A1 (en) * 2003-09-22 2005-06-30 Use-Techno Corporation Insulin secretion potentiator
PL2428519T3 (pl) 2004-08-24 2015-09-30 Btg Int Ltd Kompozycja do wytwarzania 17-winylo-trifluorometanosulfonianów jako związków pośrednich
GB0418900D0 (en) 2004-08-24 2004-09-29 Btg Int Ltd Novel salt forms
JP4813917B2 (ja) * 2005-02-22 2011-11-09 丸善製薬株式会社 皮膚化粧料
JP2007145782A (ja) * 2005-11-30 2007-06-14 Meiji Milk Prod Co Ltd ニガウリ抽出物を主成分とする血糖値降下剤、および食品・医薬品組成物
CN101768199B (zh) * 2009-12-24 2014-03-26 深圳万乐药业有限公司 醋酸阿比特龙的多晶型物及其制备方法
CN102030798B (zh) * 2010-12-17 2012-10-17 深圳万乐药业有限公司 一种醋酸阿比特龙的纯化方法
EP2766381B1 (en) * 2011-10-10 2016-07-27 Zach System Process for preparing 17-substituted steroids

Also Published As

Publication number Publication date
EP2909225A1 (en) 2015-08-26
JP2015535223A (ja) 2015-12-10
CA2888826A1 (en) 2014-05-01
US20160052958A1 (en) 2016-02-25
ES2596245T3 (es) 2017-01-05
US9340571B2 (en) 2016-05-17
KR20150079614A (ko) 2015-07-08
BR112015008855A2 (pt) 2017-07-04
WO2014064032A1 (en) 2014-05-01
AU2013336781A1 (en) 2015-05-07
EP2909225B1 (en) 2016-09-14
IL238386A (en) 2017-07-31
ITMI20121788A1 (it) 2014-04-23
IL238386A0 (en) 2015-06-30

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