DK2985275T3 - Fremgangsmåde til oprensning af beta-hydroxy-beta-methylsmørsyre - Google Patents
Fremgangsmåde til oprensning af beta-hydroxy-beta-methylsmørsyre Download PDFInfo
- Publication number
- DK2985275T3 DK2985275T3 DK13881969.3T DK13881969T DK2985275T3 DK 2985275 T3 DK2985275 T3 DK 2985275T3 DK 13881969 T DK13881969 T DK 13881969T DK 2985275 T3 DK2985275 T3 DK 2985275T3
- Authority
- DK
- Denmark
- Prior art keywords
- beta
- acid
- hydroxy
- purification
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
- C07C51/29—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with halogen-containing compounds which may be formed in situ
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310127262.XA CN104098461B (zh) | 2013-04-12 | 2013-04-12 | 一种β‑羟基‑β‑甲基丁酸的纯化方法 |
| PCT/CN2013/088762 WO2014166273A1 (zh) | 2013-04-12 | 2013-12-06 | 一种β−羟基−β−甲基丁酸的纯化方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2985275T3 true DK2985275T3 (da) | 2020-01-20 |
Family
ID=51667047
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13881969.3T DK2985275T3 (da) | 2013-04-12 | 2013-12-06 | Fremgangsmåde til oprensning af beta-hydroxy-beta-methylsmørsyre |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9598344B2 (da) |
| EP (1) | EP2985275B1 (da) |
| JP (2) | JP2016514733A (da) |
| CN (1) | CN104098461B (da) |
| AU (2) | AU2013386219B2 (da) |
| CA (1) | CA2909226A1 (da) |
| DK (1) | DK2985275T3 (da) |
| ES (1) | ES2763547T3 (da) |
| HU (1) | HUE048326T2 (da) |
| PL (1) | PL2985275T3 (da) |
| PT (1) | PT2985275T (da) |
| WO (1) | WO2014166273A1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI716495B (zh) * | 2015-11-19 | 2021-01-21 | 日商協和發酵生化股份有限公司 | 3-羥基異戊酸之一價陽離子鹽之結晶及該結晶之製造方法 |
| RU2018145506A (ru) | 2016-06-24 | 2020-07-27 | Оцука Фармасьютикал Фэктори, Инк. | Кристаллическая аминокислотная соль 3-гидроксиизовалериановой кислоты и способ ее получения |
| CN106699802B (zh) * | 2016-12-21 | 2019-01-25 | 北京嘉林药业股份有限公司 | 一种阿托伐他汀钙中间体的纯化方法 |
| WO2019016883A1 (ja) * | 2017-07-19 | 2019-01-24 | 小林香料株式会社 | ３－ヒドロキシ－３－メチルブタン酸又はその塩の製造方法 |
| CN108129294A (zh) * | 2018-01-24 | 2018-06-08 | 穆云 | 一种HMB-Ca生产工艺方法 |
| CN108484359A (zh) * | 2018-03-20 | 2018-09-04 | 江阴技源药业有限公司 | 基于HMB-Ca乙醇残液回收乙醇及有效成分的方法 |
| CN108558641A (zh) * | 2018-05-15 | 2018-09-21 | 江苏玺鑫维生素有限公司 | 一种β-羟基-β-甲基丁酸钙的制备及纯化方法 |
| CN110092714A (zh) * | 2019-04-26 | 2019-08-06 | 江西科技师范大学 | 一种2,2-二羟甲基丁酸的制备方法 |
| CN111410605A (zh) * | 2020-04-07 | 2020-07-14 | 苏州永健生物医药有限公司 | 一种β-羟基-β-甲基丁酸钙的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3228963A (en) * | 1961-12-22 | 1966-01-11 | Union Oil Co | Process for purification of complex acids |
| US4992470A (en) * | 1990-02-08 | 1991-02-12 | Iowa State University Research Foundation, Inc. | Method of enhancing immune response of mammals |
| US6090978A (en) * | 1996-07-19 | 2000-07-18 | Met-Rx Usa, Inc. | Process for manufacturing 3-hydroxy-3-methylbutanoic acid |
| CN1417190A (zh) * | 2002-12-05 | 2003-05-14 | 迈特（上海）生物科技有限公司 | β－羟基－β－甲基丁酸钙（HMB－Ca）的制备方法 |
| EP2744489A4 (en) * | 2011-08-15 | 2015-03-18 | Abbott Lab | PROCESS FOR PRODUCING HMB AND ITS SALTS |
| CN102911085A (zh) * | 2012-10-24 | 2013-02-06 | 甘肃省化工研究院 | 化合物d-2-氨氧基-3-甲基丁酸的合成工艺 |
-
2013
- 2013-04-12 CN CN201310127262.XA patent/CN104098461B/zh active Active
- 2013-12-06 EP EP13881969.3A patent/EP2985275B1/en active Active
- 2013-12-06 PT PT138819693T patent/PT2985275T/pt unknown
- 2013-12-06 PL PL13881969T patent/PL2985275T3/pl unknown
- 2013-12-06 HU HUE13881969A patent/HUE048326T2/hu unknown
- 2013-12-06 DK DK13881969.3T patent/DK2985275T3/da active
- 2013-12-06 ES ES13881969T patent/ES2763547T3/es active Active
- 2013-12-06 CA CA2909226A patent/CA2909226A1/en not_active Abandoned
- 2013-12-06 AU AU2013386219A patent/AU2013386219B2/en not_active Ceased
- 2013-12-06 JP JP2016506755A patent/JP2016514733A/ja active Pending
- 2013-12-06 WO PCT/CN2013/088762 patent/WO2014166273A1/zh active Application Filing
- 2013-12-06 US US14/783,949 patent/US9598344B2/en active Active
-
2018
- 2018-06-14 JP JP2018113345A patent/JP2018158936A/ja active Pending
- 2018-11-09 AU AU2018260972A patent/AU2018260972B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2013386219B2 (en) | 2018-08-09 |
| CA2909226A1 (en) | 2014-10-16 |
| AU2013386219A1 (en) | 2015-12-03 |
| EP2985275A4 (en) | 2016-11-23 |
| EP2985275A1 (en) | 2016-02-17 |
| CN104098461A (zh) | 2014-10-15 |
| ES2763547T3 (es) | 2020-05-29 |
| CN104098461B (zh) | 2017-06-16 |
| WO2014166273A1 (zh) | 2014-10-16 |
| AU2018260972A1 (en) | 2018-11-29 |
| PT2985275T (pt) | 2020-01-07 |
| US20160052856A1 (en) | 2016-02-25 |
| PL2985275T3 (pl) | 2020-04-30 |
| AU2018260972B2 (en) | 2020-09-03 |
| JP2018158936A (ja) | 2018-10-11 |
| HUE048326T2 (hu) | 2020-07-28 |
| US9598344B2 (en) | 2017-03-21 |
| JP2016514733A (ja) | 2016-05-23 |
| EP2985275B1 (en) | 2019-10-30 |
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