DK288183A - Fremgangsmaade til fremstilling af et oligonucleotidt terapeutisk middel - Google Patents

Fremgangsmaade til fremstilling af et oligonucleotidt terapeutisk middel Download PDF

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Publication number
DK288183A
DK288183A DK288183A DK288183A DK288183A DK 288183 A DK288183 A DK 288183A DK 288183 A DK288183 A DK 288183A DK 288183 A DK288183 A DK 288183A DK 288183 A DK288183 A DK 288183A
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Prior art keywords
oligonucleotide
organism
procedure
preparation
therapeutic agent
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DK288183A
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Danish (da)
English (en)
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DK288183D0 (da
Inventor
Richard H Tullis
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Molecular Biosystems Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23218662&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK288183(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Molecular Biosystems Inc filed Critical Molecular Biosystems Inc
Publication of DK288183D0 publication Critical patent/DK288183D0/da
Publication of DK288183A publication Critical patent/DK288183A/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
    • C12N2310/321—2'-O-R Modification

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
DK288183A 1981-10-23 1983-06-22 Fremgangsmaade til fremstilling af et oligonucleotidt terapeutisk middel DK288183A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31412481A 1981-10-23 1981-10-23
PCT/US1982/001447 WO1983001451A1 (en) 1981-10-23 1982-10-08 Oligonucleotide therapeutic agent and methods of making same

Publications (2)

Publication Number Publication Date
DK288183D0 DK288183D0 (da) 1983-06-22
DK288183A true DK288183A (da) 1983-06-22

Family

ID=23218662

Family Applications (1)

Application Number Title Priority Date Filing Date
DK288183A DK288183A (da) 1981-10-23 1983-06-22 Fremgangsmaade til fremstilling af et oligonucleotidt terapeutisk middel

Country Status (12)

Country Link
US (2) US7285537B1 (de)
EP (1) EP0092574B1 (de)
JP (2) JP2547714B2 (de)
AT (1) ATE75483T1 (de)
AU (1) AU568067B2 (de)
CA (1) CA1208147A (de)
DE (1) DE3280400D1 (de)
DK (1) DK288183A (de)
IE (1) IE58009B1 (de)
IL (1) IL67053A (de)
IT (1) IT1206311B (de)
WO (1) WO1983001451A1 (de)

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ATE75483T1 (de) 1992-05-15
AU9124382A (en) 1983-05-05
IT8223872A0 (it) 1982-10-22
DK288183D0 (da) 1983-06-22
AU568067B2 (en) 1987-12-17
EP0092574A1 (de) 1983-11-02
EP0092574B1 (de) 1992-04-29
CA1208147A (en) 1986-07-22
JP2547714B2 (ja) 1996-10-23
IL67053A (en) 1997-07-13
IT1206311B (it) 1989-04-14
US5919619A (en) 1999-07-06
DE3280400D1 (de) 1992-06-04
JPS58501771A (ja) 1983-10-20
EP0092574A4 (de) 1984-02-09
JPH08294393A (ja) 1996-11-12
WO1983001451A1 (en) 1983-04-28
IE58009B1 (en) 1993-06-16
US7285537B1 (en) 2007-10-23

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