DK2867230T3 - Fremgangsmåde til fremstilling af 3,5-disubstitueret 1,2,4-oxadiazoler - Google Patents
Fremgangsmåde til fremstilling af 3,5-disubstitueret 1,2,4-oxadiazoler Download PDFInfo
- Publication number
- DK2867230T3 DK2867230T3 DK13813965.4T DK13813965T DK2867230T3 DK 2867230 T3 DK2867230 T3 DK 2867230T3 DK 13813965 T DK13813965 T DK 13813965T DK 2867230 T3 DK2867230 T3 DK 2867230T3
- Authority
- DK
- Denmark
- Prior art keywords
- oxadiazoles
- disubstituted
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261667361P | 2012-07-02 | 2012-07-02 | |
US201361777210P | 2013-03-12 | 2013-03-12 | |
US201361783466P | 2013-03-14 | 2013-03-14 | |
PCT/US2013/049060 WO2014008257A2 (en) | 2012-07-02 | 2013-07-02 | Processes for the preparation of 3,5-disubstituted-1,2,4-oxadiazoles |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2867230T3 true DK2867230T3 (da) | 2020-04-14 |
Family
ID=49882590
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK13813965.4T DK2867230T3 (da) | 2012-07-02 | 2013-07-02 | Fremgangsmåde til fremstilling af 3,5-disubstitueret 1,2,4-oxadiazoler |
Country Status (13)
Country | Link |
---|---|
US (2) | US9040711B2 (da) |
EP (1) | EP2867230B1 (da) |
CN (1) | CN104428296B (da) |
AR (1) | AR091655A1 (da) |
AU (1) | AU2013286860B2 (da) |
BR (1) | BR112014032956B1 (da) |
CA (1) | CA2876215A1 (da) |
DK (1) | DK2867230T3 (da) |
ES (1) | ES2782509T3 (da) |
MX (1) | MX352351B (da) |
UA (1) | UA114915C2 (da) |
WO (1) | WO2014008257A2 (da) |
ZA (1) | ZA201409000B (da) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR122018001760B1 (pt) | 2007-08-13 | 2019-08-13 | Monsanto Technology Llc | método para controle de nematódeos, compostos para controlar nematódeos, bem como composições compreendendo os mesmos |
UA118254C2 (uk) | 2012-12-04 | 2018-12-26 | Монсанто Текнолоджи Ллс | Нематоцидні водні композиції концентрату суспензії |
BR112015021452A2 (pt) | 2013-03-15 | 2017-07-18 | Monsanto Technology Llc | azóis n-,c-dissubstituídos para controlar pragas de nematódeos |
HUE035844T2 (en) | 2013-03-15 | 2018-05-28 | Monsanto Technology Llc | N, C-disubstituted azoles for nematode pest control |
CN103980265A (zh) * | 2014-05-14 | 2014-08-13 | 武汉工程大学 | 3-苯基-5-(噻吩-2基)-1,2,4-噁二唑的合成工艺 |
BR112016026973B1 (pt) | 2014-05-20 | 2023-05-16 | Monsanto Technology Llc | Método para a criação de uma população de plantas de soja com resistência melhorada ao nematóide de cisto de soja (scn) de raça 1 |
JP2017538724A (ja) * | 2014-12-19 | 2017-12-28 | モンサント テクノロジー エルエルシー | 植物の農業特性を改善するための組成物及び方法 |
KR102541668B1 (ko) | 2015-03-06 | 2023-06-08 | 에이지씨 가부시키가이샤 | 1,2,4-옥사디아졸 유도체의 제조 방법 |
WO2016143654A1 (ja) * | 2015-03-06 | 2016-09-15 | 旭硝子株式会社 | 1,2,4-オキサジアゾール誘導体の製造方法 |
WO2016150937A1 (en) | 2015-03-25 | 2016-09-29 | Lonza Ltd | Method for preparation of thiophenecarbonyl chlorides |
KR102096420B1 (ko) * | 2015-03-31 | 2020-04-02 | 몬산토 테크놀로지 엘엘씨 | 2-싸이오펜카보닐 클로라이드의 제조 방법 |
CN108290877A (zh) * | 2015-11-04 | 2018-07-17 | 隆萨有限公司 | 用草酰氯制备噻吩-2-甲酰氯的方法 |
BR112018069255A2 (pt) * | 2016-03-24 | 2019-01-22 | Monsanto Technology Llc | processos para a preparação de ácidos heteroaril carboxílicos |
CN111675672A (zh) * | 2020-05-12 | 2020-09-18 | 石家庄市度智医药科技有限公司 | 一种制备阿塔鲁伦的方法 |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
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NL256329A (da) | 1959-09-29 | |||
US3218331A (en) | 1962-04-17 | 1965-11-16 | Union Carbide Corp | Preparation of substituted oxadiazoles |
US3211742A (en) | 1962-04-17 | 1965-10-12 | Union Carbide Corp | Process for preparing oxadiazoles |
NL291628A (da) | 1962-04-17 | |||
US3227725A (en) | 1962-04-17 | 1966-01-04 | Union Carbide Corp | Certain 3,5-disubstituted 1,2,4-oxadiazole compounds |
US3264318A (en) | 1964-04-29 | 1966-08-02 | Union Carbide Corp | Process for the production of substituted oxadiazoles |
JPS62241946A (ja) | 1986-04-14 | 1987-10-22 | Tonen Sekiyukagaku Kk | 熱可塑性樹脂組成物 |
JPH03258779A (ja) | 1990-03-06 | 1991-11-19 | Mitsui Toatsu Chem Inc | イミダゾール誘導体及び該イミダゾール誘導体を有効成分とする抗痙攣剤 |
DE19725450A1 (de) | 1997-06-16 | 1998-12-17 | Hoechst Schering Agrevo Gmbh | 4-Haloalkyl-3-heterocyclylpyridine und 4-Haloalkyl-5-heterocyclylpyrimidine, Verfahren zu ihrer Herstellung, sie enthaltende Mittel und ihre Verwendung als Schädlingsbekämpfungsmittel |
US6660753B2 (en) | 1999-08-19 | 2003-12-09 | Nps Pharmaceuticals, Inc. | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
CA2449544A1 (en) | 2001-06-08 | 2002-12-19 | Cytovia, Inc. | Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs |
CA2509224A1 (en) | 2002-12-18 | 2004-07-15 | Cytovia, Inc. | 3,5-disubstituted-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof |
EP3632902B1 (en) * | 2003-04-11 | 2021-07-14 | PTC Therapeutics, Inc. | 1,2,4-oxadiazole benzoic acid compound and its use for nonsense suppression and the treatment of disease |
US20050075375A1 (en) | 2003-05-14 | 2005-04-07 | Anadys Pharmaceuticals, Inc. | Heterocyclic compounds for treating hepatitis C virus |
CA2575430A1 (en) * | 2004-08-03 | 2006-02-16 | Merck & Co., Inc. | 1,3-disubstituted heteroaryl nmda/nr2b antagonists |
AU2006240789B2 (en) | 2005-04-22 | 2010-03-04 | Daiichi Sankyo Company, Limited | Heterocyclic compound |
GB0601744D0 (en) | 2006-01-27 | 2006-03-08 | Novartis Ag | Organic compounds |
AR061841A1 (es) | 2006-09-07 | 2008-09-24 | Actelion Pharmaceuticals Ltd | Derivados de tiofen-oxadiazoles, agonistas del receptor s1p1/edg1, composiciones farmaceuticas que los contienen y usos como agentes inmunomoduladores. |
DK2059513T3 (da) | 2006-09-08 | 2013-05-06 | Ptc Therapeutics Inc | Fremgangsmåde til fremstillingen af 1,2,4-oxadiazolbenzoesyrer |
JP2008120794A (ja) | 2006-10-16 | 2008-05-29 | Daiichi Sankyo Co Ltd | ヘテロ環化合物を含有する医薬組成物 |
US8486979B2 (en) | 2006-12-12 | 2013-07-16 | Abbvie Inc. | 1,2,4 oxadiazole compounds and methods of use thereof |
BR122018001760B1 (pt) | 2007-08-13 | 2019-08-13 | Monsanto Technology Llc | método para controle de nematódeos, compostos para controlar nematódeos, bem como composições compreendendo os mesmos |
WO2009041972A1 (en) | 2007-09-27 | 2009-04-02 | University Of Notre Dame Du Lac | Antibacterial compounds and methods of using same |
GB0725102D0 (en) | 2007-12-21 | 2008-01-30 | Glaxo Group Ltd | Compounds |
CA2725573A1 (en) | 2008-06-06 | 2009-12-10 | Abbott Laboratories | Novel 1,2,4 oxadiazole compounds and methods of use thereof |
ES2538301T3 (es) | 2008-11-14 | 2015-06-18 | Bayer Intellectual Property Gmbh | Compuestos de arilo con sustituyentes heterocíclicos como inhibidores HIF |
EP2202232A1 (en) | 2008-12-26 | 2010-06-30 | Laboratorios Almirall, S.A. | 1,2,4-oxadiazole derivatives and their therapeutic use |
PL2396321T3 (pl) | 2009-02-10 | 2015-10-30 | Monsanto Technology Llc | Kompozycje i sposoby zwalczania nicieni |
EP2241558A1 (en) | 2009-04-03 | 2010-10-20 | Merck Serono SA | Oxadiazole derivatives |
US9040568B2 (en) | 2009-05-29 | 2015-05-26 | Abbvie Inc. | Pharmaceutical compositions for the treatment of pain |
AR076984A1 (es) | 2009-06-08 | 2011-07-20 | Merck Serono Sa | Derivados de pirazol oxadiazol |
EP2523944A4 (en) | 2010-01-11 | 2013-06-19 | Mithridion Inc | COMPOUNDS AND COMPOSITIONS FOR IMPROVING COGNITION, METHODS OF MAKING THE SAME, AND METHODS OF TREATMENT |
US20130172311A1 (en) | 2010-05-08 | 2013-07-04 | Bayer Intellectual Property Gmbh | Substituted heterocyclyl benzyl pyrazoles, and use thereof |
EP2585458B1 (en) | 2010-06-22 | 2015-01-07 | Chiesi Farmaceutici S.p.A. | Alkaloid aminoester derivatives and medicinal compositions thereof |
WO2012012477A1 (en) | 2010-07-20 | 2012-01-26 | Bristol-Myers Squibb Company | Substituted 3-phenyl-1,2,4-oxadiazole compounds |
AU2011296048C1 (en) | 2010-09-02 | 2017-09-14 | Monsanto Technology Llc | New compositions and methods for controlling nematode pests |
-
2013
- 2013-07-02 AR ARP130102359 patent/AR091655A1/es active IP Right Grant
- 2013-07-02 AU AU2013286860A patent/AU2013286860B2/en not_active Ceased
- 2013-07-02 ES ES13813965T patent/ES2782509T3/es active Active
- 2013-07-02 US US13/933,616 patent/US9040711B2/en not_active Expired - Fee Related
- 2013-07-02 MX MX2014015794A patent/MX352351B/es active IP Right Grant
- 2013-07-02 EP EP13813965.4A patent/EP2867230B1/en active Active
- 2013-07-02 BR BR112014032956-7A patent/BR112014032956B1/pt not_active IP Right Cessation
- 2013-07-02 DK DK13813965.4T patent/DK2867230T3/da active
- 2013-07-02 WO PCT/US2013/049060 patent/WO2014008257A2/en active Application Filing
- 2013-07-02 CN CN201380033222.7A patent/CN104428296B/zh not_active Expired - Fee Related
- 2013-07-02 CA CA2876215A patent/CA2876215A1/en not_active Abandoned
- 2013-07-02 UA UAA201500768A patent/UA114915C2/uk unknown
-
2014
- 2014-12-08 ZA ZA2014/09000A patent/ZA201409000B/en unknown
-
2015
- 2015-04-20 US US14/690,537 patent/US9273037B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP2867230A2 (en) | 2015-05-06 |
UA114915C2 (uk) | 2017-08-28 |
US20140039197A1 (en) | 2014-02-06 |
AR091655A1 (es) | 2015-02-18 |
BR112014032956B1 (pt) | 2020-02-27 |
EP2867230A4 (en) | 2016-04-13 |
WO2014008257A3 (en) | 2014-02-27 |
CA2876215A1 (en) | 2014-01-09 |
CN104428296A (zh) | 2015-03-18 |
US9040711B2 (en) | 2015-05-26 |
US9273037B2 (en) | 2016-03-01 |
US20150225382A1 (en) | 2015-08-13 |
CN104428296B (zh) | 2017-11-14 |
ES2782509T3 (es) | 2020-09-15 |
AU2013286860A1 (en) | 2015-01-22 |
WO2014008257A2 (en) | 2014-01-09 |
MX2014015794A (es) | 2015-03-10 |
BR112014032956A2 (pt) | 2017-06-27 |
MX352351B (es) | 2017-11-21 |
EP2867230B1 (en) | 2020-02-12 |
AU2013286860B2 (en) | 2017-10-26 |
ZA201409000B (en) | 2017-04-26 |
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