DK2858489T3 - Rekombinante dna elementer til ekspression af rekombinante proteiner i en værtscelle - Google Patents
Rekombinante dna elementer til ekspression af rekombinante proteiner i en værtscelleInfo
- Publication number
- DK2858489T3 DK2858489T3 DK12750333.2T DK12750333T DK2858489T3 DK 2858489 T3 DK2858489 T3 DK 2858489T3 DK 12750333 T DK12750333 T DK 12750333T DK 2858489 T3 DK2858489 T3 DK 2858489T3
- Authority
- DK
- Denmark
- Prior art keywords
- expression
- host cell
- recombinant
- dna elements
- recombinant dna
- Prior art date
Links
- 108020004511 Recombinant DNA Proteins 0.000 title 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 title 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/30—Rearing or breeding invertebrates
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/60—New or modified breeds of invertebrates
- A01K67/61—Genetically modified invertebrates, e.g. transgenic or polyploid
- A01K67/65—Genetically modified arthropods
- A01K67/68—Genetically modified insects
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C12N15/866—Baculoviral vectors
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/70—Invertebrates
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/70—Invertebrates
- A01K2227/706—Insects, e.g. Drosophila melanogaster, medfly
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/01—Animal expressing industrially exogenous proteins
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14141—Use of virus, viral particle or viral elements as a vector
- C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/60—Vector systems having a special element relevant for transcription from viruses
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Environmental Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Animal Husbandry (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biodiversity & Conservation Biology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161495467P | 2011-06-10 | 2011-06-10 | |
| EP11169634 | 2011-06-10 | ||
| EP2011068381 | 2011-10-20 | ||
| EP2011072406 | 2011-12-12 | ||
| PCT/EP2012/061081 WO2012168492A2 (en) | 2011-06-10 | 2012-06-12 | Recombinant dna elements for the expression of recombinant proteins in a host cell |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2858489T3 true DK2858489T3 (da) | 2017-01-02 |
Family
ID=47296540
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK12753914.6T DK2858490T5 (en) | 2011-06-10 | 2012-06-12 | Recombinant DNA elements for expression of recombinant proteins in insects |
| DK12750333.2T DK2858489T3 (da) | 2011-06-10 | 2012-06-12 | Rekombinante dna elementer til ekspression af rekombinante proteiner i en værtscelle |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK12753914.6T DK2858490T5 (en) | 2011-06-10 | 2012-06-12 | Recombinant DNA elements for expression of recombinant proteins in insects |
Country Status (9)
| Country | Link |
|---|---|
| EP (2) | EP2858489B1 (enExample) |
| BR (1) | BR112014031039A2 (enExample) |
| CA (2) | CA2876641C (enExample) |
| DK (2) | DK2858490T5 (enExample) |
| IN (1) | IN2014MN02500A (enExample) |
| MX (1) | MX353498B (enExample) |
| PL (2) | PL2858490T3 (enExample) |
| PT (2) | PT2858490T (enExample) |
| WO (6) | WO2012168788A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2611302T3 (es) * | 2012-06-12 | 2017-05-08 | Alternative Gene Expression, S.L. | Elementos de ADN recombinante para la expresión de proteínas recombinantes en insectos |
| CN104735977B (zh) | 2012-06-12 | 2016-09-21 | 替代基因表达公司 | 用于在宿主细胞中表达重组蛋白的杆状病毒dna元件 |
| JP6063563B2 (ja) | 2012-06-12 | 2017-01-18 | オルタナティブ ジーン エクスプレッション エセ．エレ． | 宿主昆虫における組換えタンパク質の発現のためのバキュロウイルスｄｎａエレメント |
| CN103749393A (zh) * | 2013-12-20 | 2014-04-30 | 铜陵桂生生态养殖有限公司 | 一种降低蝎子死亡率的养殖方法 |
| ES2554561B1 (es) * | 2014-06-16 | 2016-09-30 | Universitat De València | Nuevos promotores derivados de baculovirus con elevada actividad en sistemas de expresión basados en baculovirus |
| AR106063A1 (es) | 2015-09-17 | 2017-12-06 | Alternative Gene Expression Sl | Expresión de proteínas recombinantes en pupas de trichoplusia ni |
| CN105087606A (zh) * | 2015-09-23 | 2015-11-25 | 天津瑞普生物技术股份有限公司 | 猪圆环病毒2型cap抗原制备方法 |
| CN105238816B (zh) * | 2015-10-26 | 2018-08-24 | 广州汉腾生物科技有限公司 | 一种表达载体 |
| WO2018176075A1 (en) * | 2017-03-27 | 2018-10-04 | The University Of Queensland | Chimeric insect-specific flaviviruses |
| HUE059211T2 (hu) | 2018-06-20 | 2022-10-28 | Fatro Spa | Vakcinák vérzéses nyúlbetegség megelõzésére |
| CN110964749A (zh) * | 2018-09-29 | 2020-04-07 | 普莱柯生物工程股份有限公司 | 一种在杆状病毒表达系统中高效表达外源蛋白的方法及其应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995017515A1 (en) * | 1993-12-23 | 1995-06-29 | University Technologies International Inc. | Methods of expressing proteins in insect cells and methods of killing insects |
| US5965393A (en) * | 1997-07-01 | 1999-10-12 | National Institute Of Immunology | Method for enhancing foreign gene expression in baculovirus expression vector system |
| RU2158505C2 (ru) * | 1998-06-09 | 2000-11-10 | Совхоз "Тепличный" | Способ приготовления углеводного корма для насекомых-опылителей |
| ES2232308B1 (es) | 2003-11-12 | 2006-10-16 | Laboratorios Calier, S.A. | Dispositivo para la cria de larvas. |
| JP4271122B2 (ja) * | 2004-10-15 | 2009-06-03 | 財団法人 ひろしま産業振興機構 | カイコでの組換えタンパク質製造のためのポリヌクレオチド |
| US8148129B2 (en) * | 2006-06-30 | 2012-04-03 | The Regents Of The University Of California | Generation of potent dominant negative transcriptional inhibitors |
| US8105827B2 (en) * | 2007-09-06 | 2012-01-31 | Academia Sinica | Protein expression systems |
| BRPI0823074A2 (pt) * | 2008-09-02 | 2012-04-10 | Alternative Gene Expression S L Algenex | método para desenvolver sequências regulatórias polinucleotìdicas, sequências regulatórias polinucleotìdicas, uso das sequências regulatórias polinucleotìdicas, vetor de expressão, células transformadas ou transfectadas, larvas de inseto transfectadas, método para produzir proteìnas recombinantes, uso do vetor de expressão e uso das larvas de inseto |
-
2012
- 2012-06-12 WO PCT/IB2012/001136 patent/WO2012168788A2/en not_active Ceased
- 2012-06-12 PT PT127539146T patent/PT2858490T/pt unknown
- 2012-06-12 DK DK12753914.6T patent/DK2858490T5/en active
- 2012-06-12 EP EP12750333.2A patent/EP2858489B1/en active Active
- 2012-06-12 EP EP12753914.6A patent/EP2858490B1/en active Active
- 2012-06-12 DK DK12750333.2T patent/DK2858489T3/da active
- 2012-06-12 MX MX2014015277A patent/MX353498B/es active IP Right Grant
- 2012-06-12 PT PT127503332T patent/PT2858489T/pt unknown
- 2012-06-12 CA CA2876641A patent/CA2876641C/en active Active
- 2012-06-12 BR BR112014031039A patent/BR112014031039A2/pt not_active Application Discontinuation
- 2012-06-12 CA CA2876343A patent/CA2876343A1/en not_active Abandoned
- 2012-06-12 WO PCT/EP2012/061088 patent/WO2012168493A2/en not_active Ceased
- 2012-06-12 PL PL12753914T patent/PL2858490T3/pl unknown
- 2012-06-12 PL PL12750333T patent/PL2858489T3/pl unknown
- 2012-06-12 IN IN2500MUN2014 patent/IN2014MN02500A/en unknown
- 2012-06-12 WO PCT/EP2012/061081 patent/WO2012168492A2/en not_active Ceased
- 2012-06-12 WO PCT/IB2012/001137 patent/WO2012168789A2/en not_active Ceased
- 2012-06-13 WO PCT/RU2012/000456 patent/WO2012169940A2/en not_active Ceased
- 2012-06-13 WO PCT/RU2012/000455 patent/WO2012169939A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP2858489B1 (en) | 2016-11-09 |
| MX353498B (es) | 2018-01-16 |
| WO2012169940A2 (en) | 2012-12-13 |
| WO2012169940A3 (en) | 2013-04-04 |
| CA2876641A1 (en) | 2012-12-13 |
| CA2876641C (en) | 2018-09-25 |
| WO2012168492A3 (en) | 2013-04-11 |
| BR112014031039A2 (pt) | 2018-05-08 |
| DK2858490T3 (en) | 2016-12-12 |
| MX2014015277A (es) | 2015-12-15 |
| WO2012168789A3 (en) | 2013-05-10 |
| PT2858490T (pt) | 2016-11-28 |
| WO2012169939A2 (en) | 2012-12-13 |
| WO2012168789A2 (en) | 2012-12-13 |
| PT2858489T (pt) | 2016-12-14 |
| WO2012169940A9 (en) | 2013-02-14 |
| EP2858489A2 (en) | 2015-04-15 |
| WO2012168492A2 (en) | 2012-12-13 |
| WO2012169939A3 (en) | 2013-05-10 |
| WO2012168788A3 (en) | 2013-05-10 |
| WO2012168493A3 (en) | 2013-05-23 |
| EP2858490A2 (en) | 2015-04-15 |
| PL2858490T3 (pl) | 2017-08-31 |
| PL2858489T3 (pl) | 2017-07-31 |
| IN2014MN02500A (enExample) | 2015-07-17 |
| CA2876343A1 (en) | 2012-12-13 |
| WO2012168493A2 (en) | 2012-12-13 |
| WO2012169939A9 (en) | 2013-02-14 |
| WO2012168493A8 (en) | 2013-04-04 |
| EP2858490B1 (en) | 2016-10-26 |
| DK2858490T5 (en) | 2017-01-23 |
| WO2012168788A2 (en) | 2012-12-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK2858489T3 (da) | Rekombinante dna elementer til ekspression af rekombinante proteiner i en værtscelle | |
| LTC2521568I2 (lt) | Plazmos kalikreiną surišantys baltymai | |
| CO7020851A2 (es) | Proteínas y péptidos modificados | |
| DK2920208T3 (da) | Rekombinante celleoverflade-capture-proteiner | |
| IL235041A0 (en) | Recombinant bacterial host cell for protein expression | |
| EP2681306A4 (en) | CELL CULTURE SYSTEM | |
| DK3578659T3 (da) | Kunstige nukelinsyremolekyler til forbedret protein- eller peptidekspression | |
| EP2661450A4 (en) | PLASMA KALLIKER BINDING PROTEINS | |
| BR112014024675A8 (pt) | célula hospedeira recombinante, cultura celular | |
| BR112014009066A2 (pt) | dna triciclo-fosforotioato | |
| HUE049119T2 (hu) | Emlõssejt-tenyészet | |
| DK2775557T3 (da) | Brændselscelle | |
| EP2664017A4 (en) | STACK OF FLOW CELLS | |
| DK2841606T3 (da) | Fusionsproteiner til at lette selektionen af celler inficeret med specifikt immunoglobulingenrekombinant vacciniavirus | |
| IL227552B (en) | Nucleic acid construct for expression of alpha-galactosidase in plants and plant cells | |
| DK3144319T3 (da) | Cellekultursammensætning indeholdende laminin-521 | |
| BR112013029769A2 (pt) | levedura recombinante | |
| BR112014003444A2 (pt) | célula hospedeira recombinante, e, método para produzir um ácido c4-dicarboxílico | |
| DK2721152T3 (da) | Dimere bindingsproteiner baseret på modificerede ubiquitiner | |
| DK2709197T3 (da) | Fastoxidbrændselscelle | |
| FI20116212L (fi) | Polypeptidi | |
| DK2462237T3 (da) | Fremgangsmåder til forbedring af rekombinant proteinekspression | |
| DE112011105455T8 (de) | Brennstoffzelle | |
| EP2800182A4 (en) | FUEL CELL SYSTEM | |
| EP2768053A4 (en) | FUEL CELL |