DK283089A - Analgetisk virksomme phenothiazinderivater - Google Patents

Analgetisk virksomme phenothiazinderivater Download PDF

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Publication number
DK283089A
DK283089A DK283089A DK283089A DK283089A DK 283089 A DK283089 A DK 283089A DK 283089 A DK283089 A DK 283089A DK 283089 A DK283089 A DK 283089A DK 283089 A DK283089 A DK 283089A
Authority
DK
Denmark
Prior art keywords
phenothiazine derivatives
branched
linear
analgetically effective
analgetically
Prior art date
Application number
DK283089A
Other languages
English (en)
Other versions
DK283089D0 (da
Inventor
Claude Garret
Claude Guyon
Bernard Plau
Gerard Taurand
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of DK283089D0 publication Critical patent/DK283089D0/da
Publication of DK283089A publication Critical patent/DK283089A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
    • C07D279/24—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom
    • C07D279/28—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom with other substituents attached to the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
DK283089A 1988-06-10 1989-06-09 Analgetisk virksomme phenothiazinderivater DK283089A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8807770A FR2632520B1 (fr) 1988-06-10 1988-06-10 Derives de la phenothiazine analgesiques

Publications (2)

Publication Number Publication Date
DK283089D0 DK283089D0 (da) 1989-06-09
DK283089A true DK283089A (da) 1989-12-11

Family

ID=9367166

Family Applications (1)

Application Number Title Priority Date Filing Date
DK283089A DK283089A (da) 1988-06-10 1989-06-09 Analgetisk virksomme phenothiazinderivater

Country Status (17)

Country Link
US (1) US5049669A (da)
EP (1) EP0346238B1 (da)
JP (1) JP2504830B2 (da)
KR (1) KR0125575B1 (da)
AT (1) ATE90346T1 (da)
AU (1) AU621120B2 (da)
CA (1) CA1325631C (da)
DE (1) DE68906965T2 (da)
DK (1) DK283089A (da)
ES (1) ES2058569T3 (da)
FR (1) FR2632520B1 (da)
HU (1) HU205752B (da)
IE (1) IE63300B1 (da)
IL (1) IL90559A (da)
MX (1) MX9203585A (da)
PT (1) PT90813B (da)
ZA (1) ZA894397B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2632521B1 (fr) * 1988-06-10 1990-09-14 Rhone Poulenc Sante Nouveaux derives de la phenothiazine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2632522B1 (fr) * 1988-06-10 1990-09-14 Rhone Poulenc Sante Nouveaux derives de la phenothiazine, leur preparation et les compositions qui les contiennent
FR2652084B1 (fr) * 1989-09-21 1991-10-31 Rhone Poulenc Sante Nouveaux derives de la phenothiazine, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2689013B1 (fr) * 1992-03-30 1995-05-05 Rhone Poulenc Rorer Sa Nouvelle application thérapeutique des dérivés de la phénothiazine.
FR2720940A1 (fr) * 1994-06-13 1995-12-15 Rhone Poulenc Rorer Sa Application du (+)-N-propyl [(pyrrolidinyl-1)-1 propyl-2]-10 phénothiazinecarboxamide comme antidépresseur.
US6191126B1 (en) * 1996-12-16 2001-02-20 Alcon Laboratories, Inc. Topical use of κ opioid agonists to treat ocular pain
US6174878B1 (en) 1999-08-31 2001-01-16 Alcon Laboratories, Inc. Topical use of kappa opioid agonists to treat otic pain
KR100826453B1 (ko) * 2004-12-28 2008-04-29 가부시키가이샤 무라타 세이사쿠쇼 이온 발생유닛 및 이온 발생장치
KR101646962B1 (ko) 2014-09-29 2016-08-10 한국과학기술연구원 CaM 저해활성을 가지는 페노싸이아진 유도체

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2956996A (en) * 1960-10-18 Alkylated phenotfflazenecarboxamede
NL222355A (da) * 1957-11-05
US3112310A (en) * 1962-01-15 1963-11-26 Searle & Co 10-alkylaminoalkylphenothiazine-2-carboxamides
FR180F (fr) * 1964-11-30 Bruneau & Cie Lab Médicament a base de dérivés d'acide phénothiazine carboxylique-3.
FR2632521B1 (fr) * 1988-06-10 1990-09-14 Rhone Poulenc Sante Nouveaux derives de la phenothiazine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2632522B1 (fr) * 1988-06-10 1990-09-14 Rhone Poulenc Sante Nouveaux derives de la phenothiazine, leur preparation et les compositions qui les contiennent

Also Published As

Publication number Publication date
DE68906965T2 (de) 1993-12-09
IE891865L (en) 1989-12-10
HU205752B (en) 1992-06-29
DE68906965D1 (de) 1993-07-15
DK283089D0 (da) 1989-06-09
PT90813A (pt) 1989-12-29
FR2632520B1 (fr) 1990-09-14
IL90559A (en) 1994-08-26
CA1325631C (fr) 1993-12-28
JP2504830B2 (ja) 1996-06-05
FR2632520A1 (fr) 1989-12-15
AU3624089A (en) 1989-12-21
IE63300B1 (en) 1995-04-05
ZA894397B (en) 1990-02-28
US5049669A (en) 1991-09-17
EP0346238A1 (fr) 1989-12-13
ES2058569T3 (es) 1994-11-01
PT90813B (pt) 1994-10-31
AU621120B2 (en) 1992-03-05
ATE90346T1 (de) 1993-06-15
IL90559A0 (en) 1990-01-18
KR0125575B1 (ko) 1998-07-01
JPH037269A (ja) 1991-01-14
MX9203585A (es) 1992-09-01
KR910000680A (ko) 1991-01-30
HUT50464A (en) 1990-02-28
EP0346238B1 (fr) 1993-06-09

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment