DK2776833T3 - Cobinder-understøttet testfremgangsmåde - Google Patents

Cobinder-understøttet testfremgangsmåde Download PDF

Info

Publication number
DK2776833T3
DK2776833T3 DK12848432.6T DK12848432T DK2776833T3 DK 2776833 T3 DK2776833 T3 DK 2776833T3 DK 12848432 T DK12848432 T DK 12848432T DK 2776833 T3 DK2776833 T3 DK 2776833T3
Authority
DK
Denmark
Prior art keywords
cobinder
testing method
supported testing
supported
testing
Prior art date
Application number
DK12848432.6T
Other languages
Danish (da)
English (en)
Inventor
Eli N Glezer
George Sigal
Original Assignee
Eli N Glezer
George Sigal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli N Glezer, George Sigal filed Critical Eli N Glezer
Application granted granted Critical
Publication of DK2776833T3 publication Critical patent/DK2776833T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • G01N33/54333Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DK12848432.6T 2011-11-11 2012-11-09 Cobinder-understøttet testfremgangsmåde DK2776833T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161558537P 2011-11-11 2011-11-11
PCT/US2012/064263 WO2013070990A1 (en) 2011-11-11 2012-11-09 Co-binder assisted assay methods

Publications (1)

Publication Number Publication Date
DK2776833T3 true DK2776833T3 (da) 2019-01-02

Family

ID=48290570

Family Applications (2)

Application Number Title Priority Date Filing Date
DK12848432.6T DK2776833T3 (da) 2011-11-11 2012-11-09 Cobinder-understøttet testfremgangsmåde
DK18192525.6T DK3467500T3 (da) 2011-11-11 2012-11-09 Cobinder-understøttede assayfremgangsmåder

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK18192525.6T DK3467500T3 (da) 2011-11-11 2012-11-09 Cobinder-understøttede assayfremgangsmåder

Country Status (6)

Country Link
US (4) US9777338B2 (cg-RX-API-DMAC7.html)
EP (2) EP2776833B1 (cg-RX-API-DMAC7.html)
JP (3) JP6300727B2 (cg-RX-API-DMAC7.html)
DK (2) DK2776833T3 (cg-RX-API-DMAC7.html)
ES (2) ES2700792T3 (cg-RX-API-DMAC7.html)
WO (1) WO2013070990A1 (cg-RX-API-DMAC7.html)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8835358B2 (en) 2009-12-15 2014-09-16 Cellular Research, Inc. Digital counting of individual molecules by stochastic attachment of diverse labels
DK2776833T3 (da) 2011-11-11 2019-01-02 Eli N Glezer Cobinder-understøttet testfremgangsmåde
EP2820158B1 (en) 2012-02-27 2018-01-10 Cellular Research, Inc. Compositions and kits for molecular counting
US10114015B2 (en) 2013-03-13 2018-10-30 Meso Scale Technologies, Llc. Assay methods
KR20220038550A (ko) 2013-03-13 2022-03-28 메소 스케일 테크놀러지즈, 엘엘시 개선된 분석 방법
JP6545682B2 (ja) 2013-08-28 2019-07-17 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company 大規模並列単一細胞分析
KR102497054B1 (ko) 2014-05-15 2023-02-06 메소 스케일 테크놀러지즈, 엘엘시 개선된 분석 방법
ES2836802T3 (es) 2015-02-27 2021-06-28 Becton Dickinson Co Códigos de barras moleculares espacialmente direccionables
EP3277843A2 (en) 2015-03-30 2018-02-07 Cellular Research, Inc. Methods and compositions for combinatorial barcoding
EP4582556A3 (en) 2015-04-23 2025-10-08 Becton, Dickinson and Company Methods and compositions for whole transcriptome amplification
WO2017044574A1 (en) 2015-09-11 2017-03-16 Cellular Research, Inc. Methods and compositions for nucleic acid library normalization
US10822637B2 (en) 2015-10-01 2020-11-03 Dynamic Biosensors Gmbh Method for detecting molecular interactions using an immobilized nucleic acid
EP3448886A4 (en) * 2016-04-26 2019-12-11 Ultivue, Inc. SUPER-HIGH-RESOLUTION IMMUNOFLUORESCENCE WITH BINDING-LIMITED PREVIEW
US10301677B2 (en) 2016-05-25 2019-05-28 Cellular Research, Inc. Normalization of nucleic acid libraries
US10202641B2 (en) 2016-05-31 2019-02-12 Cellular Research, Inc. Error correction in amplification of samples
US10640763B2 (en) 2016-05-31 2020-05-05 Cellular Research, Inc. Molecular indexing of internal sequences
US11796535B2 (en) 2016-09-16 2023-10-24 Plexbio Co., Ltd. Methods and systems for multiplex assays
IL265478B2 (en) 2016-09-26 2024-10-01 Becton Dickinson Co Measurement of protein expression using reagents with barcoded oligonucleotide sequences
EP3577232A1 (en) 2017-02-01 2019-12-11 Cellular Research, Inc. Selective amplification using blocking oligonucleotides
AU2018281745B2 (en) 2017-06-05 2022-05-19 Becton, Dickinson And Company Sample indexing for single cells
ES3014208T3 (en) 2018-05-03 2025-04-21 Becton Dickinson Co Molecular barcoding on opposite transcript ends
EP3788171B1 (en) 2018-05-03 2023-04-05 Becton, Dickinson and Company High throughput multiomics sample analysis
CN118853827A (zh) 2018-10-01 2024-10-29 贝克顿迪金森公司 确定5’转录物序列
US11932849B2 (en) 2018-11-08 2024-03-19 Becton, Dickinson And Company Whole transcriptome analysis of single cells using random priming
WO2020123384A1 (en) 2018-12-13 2020-06-18 Cellular Research, Inc. Selective extension in single cell whole transcriptome analysis
CN113574178B (zh) 2019-01-23 2024-10-29 贝克顿迪金森公司 与抗体关联的寡核苷酸
US12071617B2 (en) 2019-02-14 2024-08-27 Becton, Dickinson And Company Hybrid targeted and whole transcriptome amplification
US11965208B2 (en) 2019-04-19 2024-04-23 Becton, Dickinson And Company Methods of associating phenotypical data and single cell sequencing data
WO2021016239A1 (en) 2019-07-22 2021-01-28 Becton, Dickinson And Company Single cell chromatin immunoprecipitation sequencing assay
ES2987640T3 (es) 2019-11-08 2024-11-15 Becton Dickinson Co Uso de cebado aleatorio para obtener información de V(D)J de longitud completa para la secuenciación del repertorio inmunitario
WO2021146207A1 (en) 2020-01-13 2021-07-22 Becton, Dickinson And Company Methods and compositions for quantitation of proteins and rna
CN115335520A (zh) 2020-01-29 2022-11-11 贝克顿迪金森公司 用于通过测序对单细胞进行空间映射的条形码化的孔
US12153043B2 (en) 2020-02-25 2024-11-26 Becton, Dickinson And Company Bi-specific probes to enable the use of single-cell samples as single color compensation control
EP4150118A1 (en) 2020-05-14 2023-03-22 Becton Dickinson and Company Primers for immune repertoire profiling
US12157913B2 (en) 2020-06-02 2024-12-03 Becton, Dickinson And Company Oligonucleotides and beads for 5 prime gene expression assay
US11932901B2 (en) 2020-07-13 2024-03-19 Becton, Dickinson And Company Target enrichment using nucleic acid probes for scRNAseq
US11619589B2 (en) 2020-07-20 2023-04-04 United Arab Emirates University Method and system for detection, quantification and/or identification of an analyte in a specimen based on electrical and/or optical response to an electric field
WO2022018622A1 (en) 2020-07-20 2022-01-27 United Arab Emirates University Method and system for virus and protein-antibody interactions detection and monitoring based on optical light intensity and electrical parameters
US12391940B2 (en) 2020-07-31 2025-08-19 Becton, Dickinson And Company Single cell assay for transposase-accessible chromatin
WO2022109343A1 (en) 2020-11-20 2022-05-27 Becton, Dickinson And Company Profiling of highly expressed and lowly expressed proteins
US12392771B2 (en) 2020-12-15 2025-08-19 Becton, Dickinson And Company Single cell secretome analysis
WO2023080137A1 (ja) * 2021-11-04 2023-05-11 凸版印刷株式会社 標的物質の検出方法

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5238808A (en) 1984-10-31 1993-08-24 Igen, Inc. Luminescent metal chelate labels and means for detection
US5310687A (en) 1984-10-31 1994-05-10 Igen, Inc. Luminescent metal chelate labels and means for detection
US5147806A (en) 1988-04-29 1992-09-15 Igen, Inc. Method and apparatus for conducting electrochemiluminescence measurements
US6165729A (en) 1986-04-30 2000-12-26 Hyperion Catalysis International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
US5591581A (en) 1986-04-30 1997-01-07 Igen, Inc. Electrochemiluminescent rhenium moieties and methods for their use
US5308754A (en) 1988-03-21 1994-05-03 Kankare Jouko J Electrogenerated luminescence in solution
US5093268A (en) 1988-04-28 1992-03-03 Igen, Inc. Apparatus for conducting a plurality of simultaneous measurements of electrochemiluminescent phenomena
US5705402A (en) 1988-11-03 1998-01-06 Igen International, Inc. Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets
US5324457A (en) 1989-10-02 1994-06-28 Board Of Regents, The University Of Tx System Devices and methods for generating electrogenerated chemiluminescence
US5200314A (en) 1990-03-23 1993-04-06 Chiron Corporation Polynucleotide capture assay employing in vitro amplification
US5776672A (en) 1990-09-28 1998-07-07 Kabushiki Kaisha Toshiba Gene detection method
JPH0534345A (ja) 1991-02-19 1993-02-09 Tdk Corp 化学発光を利用する抗原・抗体の測定方法
US6872816B1 (en) 1996-01-24 2005-03-29 Third Wave Technologies, Inc. Nucleic acid detection kits
ZA929351B (en) 1991-12-11 1993-06-04 Igen Inc Electrochemiluminescent label for DNA assays.
CA2172248C (en) * 1993-09-22 2003-12-30 John Kenten Self-sustained sequence replication electrochemiluminescent nucleic acid assay
US5786141A (en) 1994-08-26 1998-07-28 Bard; Allen J. Electrogenerated chemiluminescence labels for analysis and/or referencing
US5866434A (en) 1994-12-08 1999-02-02 Meso Scale Technology Graphitic nanotubes in luminescence assays
US5643713A (en) 1995-06-07 1997-07-01 Liang; Pam Electrochemiluminescent monitoring of compounds
US5641623A (en) 1995-01-04 1997-06-24 Martin; Mark T. Electrochemiluminescence assay
NZ306051A (en) 1995-03-10 1999-11-29 Meso Scale Technologies Llc Testing using electrochemiluminescence
US6207369B1 (en) 1995-03-10 2001-03-27 Meso Scale Technologies, Llc Multi-array, multi-specific electrochemiluminescence testing
US6673533B1 (en) * 1995-03-10 2004-01-06 Meso Scale Technologies, Llc. Multi-array multi-specific electrochemiluminescence testing
US6319670B1 (en) 1995-05-09 2001-11-20 Meso Scale Technology Llp Methods and apparatus for improved luminescence assays using microparticles
US5679519A (en) 1995-05-09 1997-10-21 Oprandy; John J. Multi-label complex for enhanced sensitivity in electrochemiluminescence assay
US5589136A (en) 1995-06-20 1996-12-31 Regents Of The University Of California Silicon-based sleeve devices for chemical reactions
WO1997014028A2 (en) 1995-10-11 1997-04-17 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and method
GB9606850D0 (en) 1996-04-01 1996-06-05 Univ Liverpool An assay system and novel labelled compounds for use therwith
CA2289872C (en) * 1997-05-05 2007-07-31 Third Wave Technologies, Inc. Target-dependent reactions using structure-bridging oligonucleotides
US7314711B2 (en) * 1997-05-23 2008-01-01 Bioveris Corporation Assays employing electrochemiluminescent labels and electrochemiluminescence quenchers
FR2764381A1 (fr) 1997-06-09 1998-12-11 Univ De Neuchatel Detecteur electrochimioluminescent
US6413783B1 (en) 1997-09-18 2002-07-02 Meso Scale Technologies, Llc Assay sonication apparatus and methodology
US6200531B1 (en) 1998-05-11 2001-03-13 Igen International, Inc. Apparatus for carrying out electrochemiluminescence test measurements
US8063190B2 (en) 1998-06-02 2011-11-22 Tom Robin Caine Boyde Nucleic acid-linked conjugates and methods for making and using them
EP0962773A1 (en) 1998-06-03 1999-12-08 Mark Howard Jones Electrochemical based assay processes instrument and labels
GB9815042D0 (en) 1998-07-10 1998-09-09 Imperial College Detector
US6214552B1 (en) 1998-09-17 2001-04-10 Igen International, Inc. Assays for measuring nucleic acid damaging activities
US6136268A (en) 1999-08-17 2000-10-24 Orion Diagnostica Method for luminescence measurements
US6800608B2 (en) * 2001-06-22 2004-10-05 Beckman Coulter, Inc. Homogeneous assay of vancomycin using a stable particle-vancomycin conjugate, a novel rate enhancer, and a novel dose response modulator
US7122319B2 (en) * 2002-12-18 2006-10-17 Monogram Biosciences, Inc Multiplexed immunohistochemical assays using molecular tags
US7932060B2 (en) * 2003-04-18 2011-04-26 Becton, Dickinson And Company Immuno-amplification
US7195875B2 (en) * 2003-04-18 2007-03-27 Beckman Coulter, Inc. Oligonucleotide pairs for multiplexed binding assays
US20040248103A1 (en) 2003-06-04 2004-12-09 Feaver William John Proximity-mediated rolling circle amplification
CN101208437B (zh) 2003-12-12 2012-07-04 圣路易斯大学 检测大分子和其它分析物的生物传感器
EP2511383B1 (en) 2006-03-31 2013-12-25 Columbia University Binary probes for fluorescent analysis of nucleic acids
US8212083B2 (en) * 2006-04-27 2012-07-03 Intezyne Technologies, Inc. Heterobifunctional poly(ethylene glycol) containing acid-labile amino protecting groups and uses thereof
JP5329038B2 (ja) * 2006-12-21 2013-10-30 宇部日東化成株式会社 半導体装置及び半導体装置の製造方法
DK2210100T3 (da) 2007-11-21 2011-09-05 Univ Erasmus Medical Ct Fprbedrede fret-prober og anvendelse deraf
JP5435878B2 (ja) * 2008-02-12 2014-03-05 富士フイルム株式会社 断片化抗体を標識物質に固定した標識粒子
EP2350657A4 (en) * 2008-11-21 2013-06-12 Univ Saint Louis BIOSENSOR FOR DETECTING MULTIPLE EPITOPES ON ONE TARGET
US20100261292A1 (en) 2009-04-10 2010-10-14 Meso Scale Technologies, Llc Methods for Conducting Assays
WO2011047087A2 (en) * 2009-10-13 2011-04-21 Nanostring Technologies, Inc. Protein detection via nanoreporters
US20130059741A1 (en) * 2010-05-13 2013-03-07 Illumina, Inc. Binding assays for markers
DK2776833T3 (da) 2011-11-11 2019-01-02 Eli N Glezer Cobinder-understøttet testfremgangsmåde

Also Published As

Publication number Publication date
US20170362668A1 (en) 2017-12-21
US9777338B2 (en) 2017-10-03
EP2776833A4 (en) 2015-12-02
EP2776833B1 (en) 2018-09-05
EP3467500B1 (en) 2021-05-12
US20220033918A1 (en) 2022-02-03
US12359264B2 (en) 2025-07-15
US20250327141A1 (en) 2025-10-23
JP2020126068A (ja) 2020-08-20
EP3467500A1 (en) 2019-04-10
US11242570B2 (en) 2022-02-08
JP2018054629A (ja) 2018-04-05
ES2700792T3 (es) 2019-02-19
JP6795733B2 (ja) 2020-12-02
EP2776833A1 (en) 2014-09-17
JP2014533364A (ja) 2014-12-11
US20140315189A1 (en) 2014-10-23
DK3467500T3 (da) 2021-08-16
WO2013070990A1 (en) 2013-05-16
JP6300727B2 (ja) 2018-03-28
ES2884100T3 (es) 2021-12-10

Similar Documents

Publication Publication Date Title
DK2776833T3 (da) Cobinder-understøttet testfremgangsmåde
BR112012015988A2 (pt) método
BR112014009795A2 (pt) método
BR112014007958A2 (pt) método
BR112014001851A2 (pt) método
DK2732131T3 (da) Positioneringsfremgangsmåde
BR112014001237A2 (pt) método
BR112014002399A2 (pt) conjunto
PL3415616T3 (pl) Sposób odmładzania komórek
EP2663857A4 (en) METHOD OF DETECTION OF PROTEINS
CU24158B1 (es) Método de obtención de 1-kestosa
EP2770329A4 (en) AUTOMATED ANALYZER
DE102011100082A8 (de) Traygreifvorrichtung
EP2730040A4 (en) RADIO TRANSMISSION TEST
BR112014011913A2 (pt) método de perfuração
BR112013027644A2 (pt) método de medição de conformação
LT2991350T (lt) Vaizdų dekodavimo būdas
BR112014000879A2 (pt) deflegmador
PT2798205E (pt) Turbomáquina
CO6960543A2 (es) 2-tiopirimidinonas
EP2679827A4 (en) TURBO DEVICE
EP2726839A4 (en) SAMPLERS
BR112013009024A2 (pt) método
BR112012023891A2 (pt) método
BR112014025875A2 (pt) Método de medição