DK277682A - Fremgangsmaade til fremstilling af substituerede imidazo (1,5-a)pyridiner eller salte deraf - Google Patents

Fremgangsmaade til fremstilling af substituerede imidazo (1,5-a)pyridiner eller salte deraf Download PDF

Info

Publication number
DK277682A
DK277682A DK277682A DK277682A DK277682A DK 277682 A DK277682 A DK 277682A DK 277682 A DK277682 A DK 277682A DK 277682 A DK277682 A DK 277682A DK 277682 A DK277682 A DK 277682A
Authority
DK
Denmark
Prior art keywords
pyridines
salts
procedure
substituted imidazo
preparing substituted
Prior art date
Application number
DK277682A
Other languages
English (en)
Other versions
DK158227B (da
DK158227C (da
Inventor
N Ford
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK277682A publication Critical patent/DK277682A/da
Publication of DK158227B publication Critical patent/DK158227B/da
Application granted granted Critical
Publication of DK158227C publication Critical patent/DK158227C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40Acylated substituent nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/32Compounds having groups or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55Acids; Esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57Nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84Nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK277682A 1981-06-22 1982-06-21 Analogifremgangsmaade til fremstilling af substituerede imidazooe1,5-aaapyridiner eller 5,6,7,8-tetrahydroderivater deraf eller salte deraf DK158227C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27609481A 1981-06-22 1981-06-22
US27609481 1981-06-22

Publications (3)

Publication Number Publication Date
DK277682A true DK277682A (da) 1982-12-23
DK158227B DK158227B (da) 1990-04-16
DK158227C DK158227C (da) 1990-09-17

Family

ID=23055137

Family Applications (1)

Application Number Title Priority Date Filing Date
DK277682A DK158227C (da) 1981-06-22 1982-06-21 Analogifremgangsmaade til fremstilling af substituerede imidazooe1,5-aaapyridiner eller 5,6,7,8-tetrahydroderivater deraf eller salte deraf

Country Status (20)

Country Link
EP (1) EP0068386B1 (da)
JP (1) JPS58979A (da)
KR (1) KR890002640B1 (da)
AR (1) AR242032A1 (da)
AT (1) ATE17004T1 (da)
AU (1) AU559666B2 (da)
CA (1) CA1250844A (da)
DE (1) DE3268010D1 (da)
DK (1) DK158227C (da)
ES (5) ES513307A0 (da)
FI (1) FI75569C (da)
GB (1) GB2101595B (da)
GR (1) GR76844B (da)
HU (1) HU190701B (da)
IE (1) IE53396B1 (da)
IL (1) IL66101A (da)
NO (1) NO159276C (da)
NZ (1) NZ201023A (da)
PT (1) PT75084B (da)
ZA (1) ZA824355B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444775A (en) * 1981-06-22 1984-04-24 Ciba-Geigy Corporation Substituted imidazo[1,5-A]pyridines
DE3373467D1 (en) * 1982-06-14 1987-10-15 Takeda Chemical Industries Ltd Vinyl carboxylic acid derivatives, their production and use
US4617307A (en) * 1984-06-20 1986-10-14 Ciba-Geigy Corporation Substituted imidazo[1,5-A]pyridine derivatives as aromatase inhibitors
US4588732A (en) * 1982-12-21 1986-05-13 Ciba-Geigy Corporation Certain imidazo(1,5-a)pyridine derivatives and their use as thromboxane synthetase inhibitors
US4470986A (en) * 1982-12-21 1984-09-11 Ciba-Geigy Corporation Certain imidazo (1,5-A) pyridine aliphatic carboxylic acid derivatives and their use as selective thromboxane inhibitors
ES2036128B1 (es) * 1991-07-10 1993-12-16 Menarini Lab Procedimiento para la preparacion de 4-(imidazo)1,5-a)piridin-8l)-1,4-dihidropiridinas.
US5468757A (en) * 1994-01-31 1995-11-21 Eli Lilly And Company 6-azaindole thromboxane synthase inhibitors
ATE398124T1 (de) * 2002-11-18 2008-07-15 Novartis Pharma Gmbh Imidazoä1,5üa pyridin-derivate und methoden zur behandlung von krankheiten in verbindung mit aldosteron
US7803810B2 (en) 2007-03-09 2010-09-28 Probiodrug Ag Inhibitors

Also Published As

Publication number Publication date
ZA824355B (en) 1983-04-27
KR890002640B1 (ko) 1989-07-21
IE53396B1 (en) 1988-11-09
EP0068386A1 (de) 1983-01-05
ES8401069A1 (es) 1983-12-01
ATE17004T1 (de) 1986-01-15
PT75084A (en) 1982-07-01
FI75569C (fi) 1988-07-11
AU8506782A (en) 1983-01-06
NO159276B (no) 1988-09-05
ES8502996A1 (es) 1985-02-01
ES8502997A1 (es) 1985-02-01
GR76844B (da) 1984-09-04
NZ201023A (en) 1985-08-30
ES525687A0 (es) 1985-02-01
ES513307A0 (es) 1983-12-01
DK158227B (da) 1990-04-16
EP0068386B1 (de) 1985-12-18
IE821458L (en) 1982-12-22
NO159276C (no) 1988-12-14
AU559666B2 (en) 1987-03-19
GB2101595A (en) 1983-01-19
KR840000545A (ko) 1984-02-25
HU190701B (en) 1986-10-28
AR242032A1 (es) 1993-02-26
JPS58979A (ja) 1983-01-06
GB2101595B (en) 1985-05-30
ES525686A0 (es) 1985-02-01
FI822199A0 (fi) 1982-06-18
FI822199L (fi) 1982-12-23
DK158227C (da) 1990-09-17
PT75084B (en) 1985-07-26
CA1250844A (en) 1989-03-07
ES8502995A1 (es) 1985-02-01
FI75569B (fi) 1988-03-31
ES525688A0 (es) 1985-02-01
DE3268010D1 (en) 1986-01-30
NO822062L (no) 1982-12-23
IL66101A (en) 1985-06-30
JPH0347277B2 (da) 1991-07-18
ES525689A0 (es) 1985-02-01
ES8502994A1 (es) 1985-02-01

Similar Documents

Publication Publication Date Title
DK25081A (da) Fremgangsmaade til fremstilling af imidazo(1,2-a) pyridiner
DK138281A (da) Fremgangsmaade til fremstilling af 3-(1-piperidinylalkyl)-4h-pyrido (1,2-a) pyrimidin-4-on-derivater
NO823732L (no) Fremgangsmaate for fremstilling av nye imidazo(4,5-c)-pyridinderivater.
DK28282A (da) Fremgangsmaade til fremstilling af hexapyranoseforbindelser eller salte deraf
DK405477A (da) Fremgangsmaade til fremstilling af 5-alkoxyimidazo(1,2-a) quinolin-2-carboxylsyrer eller estere eller kationiske salte deraf
DK120783D0 (da) Fremgangsmade til fremstilling af substituerede 1h-pyrazolo(1,5-a)pyrimidiner
DK173983D0 (da) Fremgangsmade til fremstilling af imidazo (1,2-alfa)pyridiner
DK194183D0 (da) Fremgangsmade til fremstilling af 2-phenyl-imidazo(4,5-c)pyridiner
DK493083A (da) Fremgangsmaade til fremstilling af 4-oxo-1,4-dihydronicotinsyrederivater eller salte deraf
DK143183C (da) Analogifremgangsmaade til fremstilling af 1h-pyrazolo(3,4-b)pyridiner eller fysiologisk acceptable salte deraf
DK160278C (da) Analogifremgangsmaade til fremstilling af dihydropyrazolo(3,4-b)-pyridinderivater
DK277682A (da) Fremgangsmaade til fremstilling af substituerede imidazo (1,5-a)pyridiner eller salte deraf
DK133482A (da) Fremgangsmaade til fremstilling af imidazo(1,2-a)pyrimidiner
DK200280A (da) Fremgangsmaade til fremstilling af substituerede pyrido (1,2-a) pyrimidiner
DK390583D0 (da) Fremgangsmade til fremstilling af imidazo(1,2-a)pyrimidiner
ES534259A0 (es) Procedimiento para preparar nuevos derivados de imidazo (1,5-a) pirimidina
DK314682A (da) Fremgangsmaade til fremstilling af substituerede thiazolo-(3,2-a)pyrimidiner
AR229600A1 (es) Procedimiento para preparar derivados de 1,2,3-triazolo(4,5-b)(1,5)benzodiazepina
DK269478A (da) Fremgangsmaade til fremstilling af imidazo(1,2-a) pyridinforbindelser
DK44383A (da) Fremgangsmaade til fremstilling af substituerede 1,3,4-thiadiazolo(3,2-a)pyrimidiner
DK281882A (da) Fremgangsmaade til fremstilling af hidtil ukendte imidazo (1,2-a)-pyrimidiner eller deres syreadditionssalte
DK288079A (da) Fremgangsmaade til fremstilling af imidazolylethoxyderivater af pyrazolo (3,4-b) pyridin-5-methanoler
DK432582A (da) Fremgangsmaade til fremstilling af aminooxazolylforbindelser eller salte deraf
DK421981A (da) Fremgangsmaade til fremstilling af 4-aminoimidazolo (4,5-c) rifamyciner sv eller s eller salte deraf
DK146159C (da) Fremgangsmaade til fremstilling af 1-alkyl-4,5,6,7-tetrahydroimidazo(4,5-c)pyridinderivater eller salte deraf

Legal Events

Date Code Title Description
PBP Patent lapsed