FI822199L - Substituerade imidazo(1,5-a)pyridiner, foerfarande foer deras framstaellning, dessa innehaollande farmaceutiska preparat, samt deras anvaendning - Google Patents

Substituerade imidazo(1,5-a)pyridiner, foerfarande foer deras framstaellning, dessa innehaollande farmaceutiska preparat, samt deras anvaendning

Info

Publication number
FI822199L
FI822199L FI822199A FI822199A FI822199L FI 822199 L FI822199 L FI 822199L FI 822199 A FI822199 A FI 822199A FI 822199 A FI822199 A FI 822199A FI 822199 L FI822199 L FI 822199L
Authority
FI
Finland
Prior art keywords
pharmaceutical
pharmaceutical form
pyridiner
imidazo
substitute
Prior art date
Application number
FI822199A
Other languages
English (en)
Other versions
FI822199A0 (fi
FI75569C (fi
FI75569B (fi
Inventor
Neville Ford
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI822199A0 publication Critical patent/FI822199A0/fi
Publication of FI822199L publication Critical patent/FI822199L/fi
Application granted granted Critical
Publication of FI75569B publication Critical patent/FI75569B/fi
Publication of FI75569C publication Critical patent/FI75569C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40Acylated substituent nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/32Compounds having groups or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55Acids; Esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57Nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84Nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI822199A 1981-06-22 1982-06-18 Analogifoerfarande foer framstaellning av terapeutiskt verkande imidazo/1,5-a/pyridiner. FI75569C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27609481A 1981-06-22 1981-06-22
US27609481 1981-06-22

Publications (4)

Publication Number Publication Date
FI822199A0 FI822199A0 (fi) 1982-06-18
FI822199L true FI822199L (fi) 1982-12-23
FI75569B FI75569B (fi) 1988-03-31
FI75569C FI75569C (fi) 1988-07-11

Family

ID=23055137

Family Applications (1)

Application Number Title Priority Date Filing Date
FI822199A FI75569C (fi) 1981-06-22 1982-06-18 Analogifoerfarande foer framstaellning av terapeutiskt verkande imidazo/1,5-a/pyridiner.

Country Status (20)

Country Link
EP (1) EP0068386B1 (fi)
JP (1) JPS58979A (fi)
KR (1) KR890002640B1 (fi)
AR (1) AR242032A1 (fi)
AT (1) ATE17004T1 (fi)
AU (1) AU559666B2 (fi)
CA (1) CA1250844A (fi)
DE (1) DE3268010D1 (fi)
DK (1) DK158227C (fi)
ES (5) ES513307A0 (fi)
FI (1) FI75569C (fi)
GB (1) GB2101595B (fi)
GR (1) GR76844B (fi)
HU (1) HU190701B (fi)
IE (1) IE53396B1 (fi)
IL (1) IL66101A (fi)
NO (1) NO159276C (fi)
NZ (1) NZ201023A (fi)
PT (1) PT75084B (fi)
ZA (1) ZA824355B (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444775A (en) * 1981-06-22 1984-04-24 Ciba-Geigy Corporation Substituted imidazo[1,5-A]pyridines
EP0098690B1 (en) * 1982-06-14 1987-09-09 Takeda Chemical Industries, Ltd. Vinyl carboxylic acid derivatives, their production and use
US4617307A (en) * 1984-06-20 1986-10-14 Ciba-Geigy Corporation Substituted imidazo[1,5-A]pyridine derivatives as aromatase inhibitors
US4470986A (en) * 1982-12-21 1984-09-11 Ciba-Geigy Corporation Certain imidazo (1,5-A) pyridine aliphatic carboxylic acid derivatives and their use as selective thromboxane inhibitors
US4588732A (en) * 1982-12-21 1986-05-13 Ciba-Geigy Corporation Certain imidazo(1,5-a)pyridine derivatives and their use as thromboxane synthetase inhibitors
ES2036128B1 (es) * 1991-07-10 1993-12-16 Menarini Lab Procedimiento para la preparacion de 4-(imidazo)1,5-a)piridin-8l)-1,4-dihidropiridinas.
US5468757A (en) * 1994-01-31 1995-11-21 Eli Lilly And Company 6-azaindole thromboxane synthase inhibitors
PT1565463E (pt) * 2002-11-18 2008-09-10 Novartis Ag Derivados de imidazo[1,5-a]piridina e métodos para tratar doenças mediadas pela aldosterona
EP2118101B1 (en) 2007-03-09 2012-09-26 Probiodrug AG Imidazo [1,5-a] pyridine derivatives as inhibitors of glutaminyl cyclase

Also Published As

Publication number Publication date
FI822199A0 (fi) 1982-06-18
CA1250844A (en) 1989-03-07
ES8401069A1 (es) 1983-12-01
ES513307A0 (es) 1983-12-01
EP0068386B1 (de) 1985-12-18
DK277682A (da) 1982-12-23
KR840000545A (ko) 1984-02-25
ES525689A0 (es) 1985-02-01
ES8502995A1 (es) 1985-02-01
ES8502994A1 (es) 1985-02-01
EP0068386A1 (de) 1983-01-05
ZA824355B (en) 1983-04-27
DK158227B (da) 1990-04-16
ES8502996A1 (es) 1985-02-01
ES525686A0 (es) 1985-02-01
DE3268010D1 (en) 1986-01-30
IE53396B1 (en) 1988-11-09
NO159276B (no) 1988-09-05
ES525687A0 (es) 1985-02-01
IL66101A (en) 1985-06-30
FI75569C (fi) 1988-07-11
HU190701B (en) 1986-10-28
JPH0347277B2 (fi) 1991-07-18
NO159276C (no) 1988-12-14
AR242032A1 (es) 1993-02-26
KR890002640B1 (ko) 1989-07-21
FI75569B (fi) 1988-03-31
AU559666B2 (en) 1987-03-19
GB2101595A (en) 1983-01-19
AU8506782A (en) 1983-01-06
ES8502997A1 (es) 1985-02-01
ES525688A0 (es) 1985-02-01
DK158227C (da) 1990-09-17
PT75084B (en) 1985-07-26
PT75084A (en) 1982-07-01
NO822062L (no) 1982-12-23
IE821458L (en) 1982-12-22
GB2101595B (en) 1985-05-30
NZ201023A (en) 1985-08-30
GR76844B (fi) 1984-09-04
JPS58979A (ja) 1983-01-06
ATE17004T1 (de) 1986-01-15

Similar Documents

Publication Publication Date Title
NO159724C (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme imidazo(1,2-a)-pyraziner.
FI810147L (fi) Imidazo/1,2-a/pyridiner foerfande foer deras framstaellning och dessa innehaollande farmaceutiska kompositioner
IT1141960B (it) Procedimento per la preparazione di uretani aromatici
FI820178L (fi) Fosforylfoereningar foerfarande foer deras framstaellning dessa foereningar innehaollande farmaceutiska preparat samt deras anvaendning
RO86213A (ro) Procedeu pentru prepararea izobutenei
FI822187A0 (fi) Farmaceutiska preparat
FI822199L (fi) Substituerade imidazo(1,5-a)pyridiner, foerfarande foer deras framstaellning, dessa innehaollande farmaceutiska preparat, samt deras anvaendning
NO834711L (no) Imidazo(1,5-a)pyridin-derivater
AR229519A1 (es) Procedimiento de preparacion de derivados de 2,3-dihidro-9-fenil-1h-pirazolo(1,2-a)-indazolio
FI821035L (fi) Imidazo/1,2-a/pyrimidinderivat, deras framstaellning och anvaendning vid sjukvaord
FI864891A (fi) Foerfarande foer framstaellning av 6,7,8,9-tetrahydro-10-metylpyrido/1,2-a/indol-9-aminer och deras derivat.
IT1172120B (it) Procentimento per la produzione di agenti di carbocementazione
IT8222353A1 (it) Tiazolo(3,2-a) primidine sostituite e procedimento per la loro preparazione
FI834664A0 (fi) Substituerade imidazo(1,5-a)pyridiner
IT1190920B (it) Composti biciclici e procedimento per la loro preparazione
ES518499A0 (es) Procedimiento para la preparacion de nuevas imidazo(1,2-a)pirimidinas.
RO85277A (ro) Procedeu pentru prepararea unor imidazolil propionitrili
IT1172155B (it) Procedimento per la produzione di agenti di carbocementazione
NL187806C (nl) Werkwijze voor de continue bereiding van zuurfluoride.
IT1210971B (it) Composti biciclici eprocedimento per la loro preparazione.
IT1155455B (it) Procedimento per la preparazione di imidazolilvinileteri
IT8224536A0 (it) Procedimento di preparazione di mononitroclorobenzene.
FI811198L (fi) Pyrrolo(3,4-c)kinolinderivat, foerfaranden foer deras framstaellning samt farmaceutiska sammansaettningar
IT1210970B (it) Composti biciclici e procedimento per la loro preparazione.
IT1157922B (it) Procedimento per la preparazione di sclareolo

Legal Events

Date Code Title Description
PC Transfer of assignment of patent

Owner name: NOVARTIS AG

MM Patent lapsed
MM Patent lapsed

Owner name: NOVARTIS AG