DK274881A - Diketopiperazinderivater og fremgangsmaade til fremstilling deraf - Google Patents

Diketopiperazinderivater og fremgangsmaade til fremstilling deraf

Info

Publication number
DK274881A
DK274881A DK274881A DK274881A DK274881A DK 274881 A DK274881 A DK 274881A DK 274881 A DK274881 A DK 274881A DK 274881 A DK274881 A DK 274881A DK 274881 A DK274881 A DK 274881A
Authority
DK
Denmark
Prior art keywords
procedures
preparing
diketopiperazine derivatives
diketopiperazine
immune system
Prior art date
Application number
DK274881A
Other languages
English (en)
Other versions
DK149591B (da
DK149591C (da
Inventor
G Heavner
F S Tjoeng
G Goldstein
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of DK274881A publication Critical patent/DK274881A/da
Publication of DK149591B publication Critical patent/DK149591B/da
Application granted granted Critical
Publication of DK149591C publication Critical patent/DK149591C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Paper (AREA)
  • Coloring (AREA)
  • Cereal-Derived Products (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
DK274881A 1980-06-23 1981-06-22 Analogifremgangsmaade til fremstilling af 2,5-diketopiperazinderivater eller syreadditionssalte deraf DK149591C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16222880 1980-06-23
US06/162,228 US4289759A (en) 1980-06-23 1980-06-23 Immunoregulatory diketopiperazine compounds

Publications (3)

Publication Number Publication Date
DK274881A true DK274881A (da) 1981-12-24
DK149591B DK149591B (da) 1986-08-04
DK149591C DK149591C (da) 1987-02-09

Family

ID=22584724

Family Applications (1)

Application Number Title Priority Date Filing Date
DK274881A DK149591C (da) 1980-06-23 1981-06-22 Analogifremgangsmaade til fremstilling af 2,5-diketopiperazinderivater eller syreadditionssalte deraf

Country Status (19)

Country Link
US (1) US4289759A (da)
EP (1) EP0043219B1 (da)
JP (1) JPS5732272A (da)
AT (1) ATE4897T1 (da)
AU (1) AU544522B2 (da)
CA (1) CA1199024A (da)
DE (1) DE3161122D1 (da)
DK (1) DK149591C (da)
ES (1) ES503306A0 (da)
FI (1) FI75563C (da)
GR (1) GR74548B (da)
IE (1) IE51312B1 (da)
IL (1) IL63147A0 (da)
NO (1) NO157862C (da)
NZ (1) NZ197386A (da)
PH (1) PH17520A (da)
PT (1) PT73202B (da)
YU (1) YU42410B (da)
ZA (1) ZA814218B (da)

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US5714167A (en) * 1992-06-15 1998-02-03 Emisphere Technologies, Inc. Active agent transport systems
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US5958457A (en) * 1993-04-22 1999-09-28 Emisphere Technologies, Inc. Compositions for the delivery of antigens
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US6051258A (en) * 1995-06-07 2000-04-18 Emisphere Technologies, Inc. Proteinoid emulsions and methods for preparation and use thereof
US5667806A (en) * 1995-06-07 1997-09-16 Emisphere Technologies, Inc. Spray drying method and apparatus
US5824345A (en) * 1995-06-07 1998-10-20 Emisphere Technologies, Inc. Fragrances and flavorants
US5750147A (en) 1995-06-07 1998-05-12 Emisphere Technologies, Inc. Method of solubilizing and encapsulating itraconazole
DE19681560T1 (de) * 1995-09-11 1998-08-20 Emisphere Tech Inc Verfahren zur Herstellung von omega-Aminoalkansäure-Derivaten aus Cycloalkanonen
EP0904065A4 (en) 1996-06-14 2000-06-14 Emisphere Tech Inc MICRO-ENCLOSED FRAGRANCES AND PRODUCTION METHOD
US6358504B1 (en) 1997-02-07 2002-03-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
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US5879681A (en) * 1997-02-07 1999-03-09 Emisphere Technolgies Inc. Compounds and compositions for delivering active agents
US6313088B1 (en) 1997-02-07 2001-11-06 Emisphere Technologies, Inc. 8-[(2-hydroxy-4-methoxy benzoyl) amino]-octanoic acid compositions for delivering active agents
US6060513A (en) * 1997-02-07 2000-05-09 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5804688A (en) * 1997-02-07 1998-09-08 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5990166A (en) * 1997-02-07 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5876710A (en) * 1997-02-07 1999-03-02 Emisphere Technologies Inc. Compounds and compositions for delivering active agents
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US5962710A (en) * 1997-05-09 1999-10-05 Emisphere Technologies, Inc. Method of preparing salicyloylamino acids
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US8217047B2 (en) * 2008-05-27 2012-07-10 Dmi Acquisition Corp. Therapeutic methods and compounds
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US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
BRPI0914308B8 (pt) 2008-06-20 2021-06-22 Mannkind Corp sistema de inalação
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8116047B2 (en) * 2008-12-18 2012-02-14 Sandisk Technologies Inc. Electrostatic discharge protective circuit having rise time detector and discharge sustaining circuitry
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
CA2754595C (en) 2009-03-11 2017-06-27 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
KR101875969B1 (ko) 2009-06-12 2018-07-06 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
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Also Published As

Publication number Publication date
PT73202A (en) 1981-07-01
ES8300718A1 (es) 1982-11-01
FI811950L (fi) 1981-12-24
ES503306A0 (es) 1982-11-01
NZ197386A (en) 1984-07-06
DK149591B (da) 1986-08-04
NO812126L (no) 1981-12-28
EP0043219A1 (en) 1982-01-06
PH17520A (en) 1984-09-13
YU42410B (en) 1988-08-31
ZA814218B (en) 1983-02-23
GR74548B (da) 1984-06-29
EP0043219B1 (en) 1983-10-05
AU544522B2 (en) 1985-06-06
JPS5732272A (en) 1982-02-20
ATE4897T1 (de) 1983-10-15
YU157281A (en) 1984-02-29
CA1199024A (en) 1986-01-07
IE811383L (en) 1981-12-23
US4289759A (en) 1981-09-15
FI75563C (fi) 1988-07-11
PT73202B (en) 1983-04-26
NO157862B (no) 1988-02-22
DE3161122D1 (en) 1983-11-10
FI75563B (fi) 1988-03-31
IE51312B1 (en) 1986-11-26
NO157862C (no) 1988-06-01
AU7124681A (en) 1982-01-07
DK149591C (da) 1987-02-09
IL63147A0 (en) 1981-09-13

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