DK2744519T3 - Sammensætninger til foryngelse af hud - Google Patents

Sammensætninger til foryngelse af hud Download PDF

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DK2744519T3
DK2744519T3 DK12823411.9T DK12823411T DK2744519T3 DK 2744519 T3 DK2744519 T3 DK 2744519T3 DK 12823411 T DK12823411 T DK 12823411T DK 2744519 T3 DK2744519 T3 DK 2744519T3
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formulation
skin
pfc
approx
mixture
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DK12823411.9T
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Kate Somerville
Fred Khoury
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Kate Somerville Skincare Llc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/69—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing fluorine
    • A61K8/70—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing fluorine containing perfluoro groups, e.g. perfluoroethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/046—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A61K8/062—Oil-in-water emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31—Hydrocarbons
    • A61K8/315—Halogenated hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/18—Antioxidants, e.g. antiradicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02—Preparations containing skin colorants, e.g. pigments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/04—Preparations for care of the skin for chemically tanning the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/06—Preparations for care of the skin for countering cellulitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/16—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant characterised by the actuating means
    • B65D83/20—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant characterised by the actuating means operated by manual action, e.g. button-type actuator or actuator caps
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/75—Aerosol containers not provided for in groups B65D83/16 - B65D83/74
    • B65D83/752—Aerosol containers not provided for in groups B65D83/16 - B65D83/74 characterised by the use of specific products or propellants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/22—Gas releasing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/591—Mixtures of compounds not provided for by any of the codes A61K2800/592 - A61K2800/596
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/87—Application Devices; Containers; Packaging

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Dispersion Chemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mechanical Engineering (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (13)

1. Formulering der omfatter: ca. 1-10% af en blanding af perfluorcarbonatomer (PFC'er) med mindst tre forskellige molekylære vægte; og ca. 0,001-5% hyaluronsyre (HA) med molekylær vægt på ca. 100 kDa eller mindre, fyldt i en håndholdt aerosolspraybeholder.
2. Formulering ifølge krav 1, hvor formuleringen er vandholdig eller omfatter en olie- og vandemulsion.
3. Formulering ifølge et hvilket som helst af kravene 1-2, hvor blandingen af PFC'er omfatter perfluorpropan, perfluorbutan, perfluorpentan, perfluorhexan, perfluordecalin, perfluordimethyl-cyclohexan, perfluorperhydrophenanthren, pentafluorpropan, perfluortripropylamin, C6-C9-perfluoralkaner, perfluorperhydrofluoranthren, perfluordecalin, perfluorperhydro-phenanthren, bis(perfluor-hexyl)-l,2-ethen, perfluor-l,3-dimethylcyclohexan, perfluor-methyldecalin, perfluorisopropyldecalin, en blanding af perfluordixylylmethan og perfluordixylylethan, og/eller en blanding af perfluorperhydrophenanthren og perfluor-n-butyl-decalin.
4. Formulering ifølge et hvilket som helst af kravene 1-3, hvor formuleringen ikke omfatter mere end 5% af blandingen af PFC'er.
5. Formulering ifølge et hvilket som helst af kravene 1-3, hvor formuleringen omfatter ca. 10% af blandingen af PFC'er.
6. Formulering ifølge et hvilket som helst af kravene 1-5, hvor formuleringen endvidere omfatter en eller flere af niacin eller andre vitaminer, mineraler, enzymer, aminosyrer, antioxidanter, blodudvidende ingredienser eller naturlige behagelige dufte.
7. Formulering ifølge et hvilket som helst af kravene 1-6, endvidere omfattende en eller flere af: en intracellulær oxygenbooster (0,005-30%); emulgatorer (0,1- 20%); rheologimodifikatorer (0,05-5%); fugtighedsbevarende stoffer (0,5-8%); overfladeaktive midler (0,1-5%); blødgørende midler (0,1-20%); pH-modifikatorer (0,005-2%); antimikrobielle midler (0,001-3%); farvestoffer (0,001-30%); aromaer (0,005-5%); eller antioxidanter (0,005-5%).
8. Formulering ifølge krav 7, hvor den intracellulære oxygenbooster er et ekstrakt fra Tropaeolum Majus blomst/blad/stilk; emulgatoren er en ikke-ionisk, kationisk, anionisk eller polymerisk emulgator; rheologimodifikatoren er en polyacrylsyrepolymer, xanthangummi, cellulosegummi, silicat, alginat, eller hydrocolloid; det fugtighedsbevarende middel er propandiol, glycerin eller en anden glycol; det overfladeaktive middel er kationisk, anionisk, ethoxyleret eller ikke-ethoxyleret; det antimikrobielle middel er salicylsyre eller et konserveringsmiddel; farvestoffet er en FD&C-farve, jernoxid, eller titaniumdioxid; aromaen er i form af en duft eller æterisk olie; og antioxidanten er ascorbinsyre.
9. Formulering ifølge et hvilket som helst af kravene 1-8, hvor (a) den molekylære vægt af HA'en er mindre end eller ca. 50 kDa; (b) HA er i en mængde på ca. 0,1%; eller (c) den molekylære vægt af HA'en er mindre end eller ca. 50 kDa og HA er i en mængde på ca. 0,1%.
10. Formulering ifølge et hvilket som helst af kravene 1-9, hvor formuleringen er delvist mættet, mættet eller overmættet med oxygen.
11. Formulering ifølge krav 1, hvor formuleringen omfatter: vand/aqua/eau, perfluorhexan, perfluorperhydrophenanthren, dimethicon, propandiol, neopentylglycoldiheptanoat, perfluordecalin, ekstrakt fra Tropaeolum Majus blomst/blad/stilk, isododecan, cyclopentasiloxan, glycerylstearat, cetearylalkohol, stearinsyre, natriumlauroylglutamat, cyclohexasiloxan, acrylater/C10-30-alkylacrylat-krydspolymer, hydrolyseret hyaluronsyre, phospholipider, retinylpalmitat, tocopherylacetat, ascorbylpalmitat, natriumhydroxid, ehylhexylglycerin, kamilleolie og phenoxyethanol.
12. Anvendelse af formuleringen ifølge et hvilket som helst af kravene 1-11 i en kosmetikfremgangsmåde.
13. Anvendelse ifølge krav 12 hvor formuleringen anvendes: (a) som en foundation til make-up, hvor formuleringen endvidere omfatter et eller flere egnede farvestoffer; (b) til at øge hudfugtighed, og/eller reducere fine linjer og rynker; eller (c) til behandling af cellulit, hvor formuleringen endvidere omfatter adipogeneseinhibitorer, lipogeneseinhibitorer og/eller eller lipolytiske midler.
DK12823411.9T 2011-08-16 2012-08-16 Sammensætninger til foryngelse af hud DK2744519T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161524021P 2011-08-16 2011-08-16
PCT/US2012/051158 WO2013025916A2 (en) 2011-08-16 2012-08-16 Dermal rejuvenation compositions and methods

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DK2744519T3 true DK2744519T3 (da) 2019-01-21

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US (8) US8980227B2 (da)
EP (1) EP2744519B1 (da)
KR (1) KR20140089340A (da)
CN (2) CN107412001B (da)
AU (2) AU2012296465B2 (da)
CA (1) CA2845570A1 (da)
DK (1) DK2744519T3 (da)
ES (1) ES2703516T3 (da)
HK (3) HK1199208A1 (da)
HR (1) HRP20182175T1 (da)
PL (1) PL2744519T3 (da)
PT (1) PT2744519T (da)
TW (1) TW201321022A (da)
WO (1) WO2013025916A2 (da)

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US8980228B2 (en) 2015-03-17
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CN107412001B (zh) 2020-08-18
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PT2744519T (pt) 2019-01-17
WO2013025916A2 (en) 2013-02-21
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US20180228715A1 (en) 2018-08-16
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US20130177505A1 (en) 2013-07-11
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US20190151220A1 (en) 2019-05-23
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