DK26793D0 - Benzofuranyl- eller dihydrobenzofuranyl-substituerede tricycliske benzazepiner, der anvendelse og fremstilling - Google Patents

Benzofuranyl- eller dihydrobenzofuranyl-substituerede tricycliske benzazepiner, der anvendelse og fremstilling

Info

Publication number
DK26793D0
DK26793D0 DK93267A DK26793A DK26793D0 DK 26793 D0 DK26793 D0 DK 26793D0 DK 93267 A DK93267 A DK 93267A DK 26793 A DK26793 A DK 26793A DK 26793 D0 DK26793 D0 DK 26793D0
Authority
DK
Denmark
Prior art keywords
dihydrobenzofuranyl
benzofuranyl
preparing
dihydrofuran
cyclopentene
Prior art date
Application number
DK93267A
Other languages
Danish (da)
English (en)
Inventor
Rolf Hohlweg
Erik Bardrum Nielsen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Priority to DK93267A priority Critical patent/DK26793D0/da
Publication of DK26793D0 publication Critical patent/DK26793D0/da
Priority to JP51947094A priority patent/JP3779319B2/ja
Priority to EP94908289A priority patent/EP0688320B1/en
Priority to AT94908289T priority patent/ATE179700T1/de
Priority to ES94908289T priority patent/ES2133542T3/es
Priority to CN94191882A priority patent/CN1045957C/zh
Priority to PCT/DK1994/000069 priority patent/WO1994020472A1/en
Priority to NZ262098A priority patent/NZ262098A/en
Priority to AU61386/94A priority patent/AU682494B2/en
Priority to CA002157668A priority patent/CA2157668C/en
Priority to DK94908289T priority patent/DK0688320T3/da
Priority to DE69418321T priority patent/DE69418321T2/de
Priority to KR1019950703762A priority patent/KR960701022A/ko
Priority to TW083101509A priority patent/TW279861B/zh
Priority to IL10873094A priority patent/IL108730A/en
Priority to US08/202,401 priority patent/US5512562A/en
Priority to ZA941377A priority patent/ZA941377B/xx
Priority to NO953543A priority patent/NO953543D0/no
Priority to FI954229A priority patent/FI111944B/fi
Priority to GR990401950T priority patent/GR3030864T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/32—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK93267A 1993-03-10 1993-03-10 Benzofuranyl- eller dihydrobenzofuranyl-substituerede tricycliske benzazepiner, der anvendelse og fremstilling DK26793D0 (da)

Priority Applications (20)

Application Number Priority Date Filing Date Title
DK93267A DK26793D0 (da) 1993-03-10 1993-03-10 Benzofuranyl- eller dihydrobenzofuranyl-substituerede tricycliske benzazepiner, der anvendelse og fremstilling
KR1019950703762A KR960701022A (ko) 1993-03-10 1994-02-18 헤테로사이클릭 화합물, 이의 용도 및 제조방법(Heterocyclic compounds, their use and preparation)
AU61386/94A AU682494B2 (en) 1993-03-10 1994-02-18 Heterocyclic compounds, their use and preparation
DK94908289T DK0688320T3 (da) 1993-03-10 1994-02-18 Heterocycliske forbindelser, anvendelse og fremstilling deraf
AT94908289T ATE179700T1 (de) 1993-03-10 1994-02-18 Tricyclische benzodiazepine, ihr verwendung und herstellung
ES94908289T ES2133542T3 (es) 1993-03-10 1994-02-18 Benzodiazepinas triciclicas, utilizacion y preparacion.
CN94191882A CN1045957C (zh) 1993-03-10 1994-02-18 三环苯并吖庚因,它们的应用和制备
PCT/DK1994/000069 WO1994020472A1 (en) 1993-03-10 1994-02-18 Heterocyclic compounds, their use and preparation
NZ262098A NZ262098A (en) 1993-03-10 1994-02-18 Phenyl substituted tricyclic benzazepine derivatives
JP51947094A JP3779319B2 (ja) 1993-03-10 1994-02-18 複素環式化合物、それらの使用および製法
CA002157668A CA2157668C (en) 1993-03-10 1994-02-18 Tricyclic 2,3,4,5-tetrahydro-1h-3-benzazepines, their use and preparation
EP94908289A EP0688320B1 (en) 1993-03-10 1994-02-18 Tricyclic benzodiazepins, their use and preparation
DE69418321T DE69418321T2 (de) 1993-03-10 1994-02-18 Tricyclische benzodiazepine, ihr verwendung und herstellung
IL10873094A IL108730A (en) 1993-03-10 1994-02-22 Heterocyclic compounds, their preparation and pharmaceutical preparations containing them
TW083101509A TW279861B (es) 1993-03-10 1994-02-22
US08/202,401 US5512562A (en) 1993-03-10 1994-02-24 Tricyclic 2,3,4,5-tetrahydro-1H-3-benzapines
ZA941377A ZA941377B (en) 1993-03-10 1994-02-28 Heterocyclic compounds, their use and preparation
NO953543A NO953543D0 (no) 1993-03-10 1995-09-08 Heterosykliske forbindelser, deres anvendelse og fremstilling
FI954229A FI111944B (fi) 1993-03-10 1995-09-08 Menetelmä farmakologisesti aktiivisten trisyklisten bentsatsepiinien valmistamiseksi
GR990401950T GR3030864T3 (en) 1993-03-10 1999-07-27 Heterocyclic compounds, their use and preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK93267A DK26793D0 (da) 1993-03-10 1993-03-10 Benzofuranyl- eller dihydrobenzofuranyl-substituerede tricycliske benzazepiner, der anvendelse og fremstilling

Publications (1)

Publication Number Publication Date
DK26793D0 true DK26793D0 (da) 1993-03-10

Family

ID=8091615

Family Applications (2)

Application Number Title Priority Date Filing Date
DK93267A DK26793D0 (da) 1993-03-10 1993-03-10 Benzofuranyl- eller dihydrobenzofuranyl-substituerede tricycliske benzazepiner, der anvendelse og fremstilling
DK94908289T DK0688320T3 (da) 1993-03-10 1994-02-18 Heterocycliske forbindelser, anvendelse og fremstilling deraf

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK94908289T DK0688320T3 (da) 1993-03-10 1994-02-18 Heterocycliske forbindelser, anvendelse og fremstilling deraf

Country Status (19)

Country Link
US (1) US5512562A (es)
EP (1) EP0688320B1 (es)
JP (1) JP3779319B2 (es)
KR (1) KR960701022A (es)
CN (1) CN1045957C (es)
AT (1) ATE179700T1 (es)
AU (1) AU682494B2 (es)
CA (1) CA2157668C (es)
DE (1) DE69418321T2 (es)
DK (2) DK26793D0 (es)
ES (1) ES2133542T3 (es)
FI (1) FI111944B (es)
GR (1) GR3030864T3 (es)
IL (1) IL108730A (es)
NO (1) NO953543D0 (es)
NZ (1) NZ262098A (es)
TW (1) TW279861B (es)
WO (1) WO1994020472A1 (es)
ZA (1) ZA941377B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2745815B1 (fr) * 1996-03-08 1998-06-26 Synthelabo Derives de benzofurane, leur preparations et compositions pharmaceutiques les comprenant
AU2030197A (en) * 1996-03-08 1997-09-22 Synthelabo 2-aminoethyl-benzofuran derivatives, preparation thereof and therapeutical use thereof
FR2752840A1 (fr) * 1996-08-29 1998-03-06 Synthelabo Derives de benzothiophene, leur preparation et leur application en therapeutique
CA2283083C (en) 1997-03-12 2007-09-04 Novo Nordisk A/S Use of 2,3,4,5-tetrahydro-1h-3-benzazepines for the manufacture of a pharmaceutical composition for the treatment of sleep disorders
US6528529B1 (en) * 1998-03-31 2003-03-04 Acadia Pharmaceuticals Inc. Compounds with activity on muscarinic receptors
US6465453B1 (en) * 1998-06-30 2002-10-15 Eli Lilly And Company Azepine derivatives having effects on serotonin related systems
DE60206762T2 (de) 2001-07-13 2006-07-13 Pharmacia & Upjohn Co. Llc, Kalamazoo Hexahydroazepino(4,5-g)indole und -indoline als 5-ht rezeptor-liganden
GB0412314D0 (en) * 2004-06-02 2004-07-07 Glaxo Group Ltd Compounds
GB0414795D0 (en) * 2004-07-01 2004-08-04 Glaxo Group Ltd Compounds
EP2528922B1 (en) * 2010-01-27 2017-08-02 AB Pharma Ltd Polyheterocyclic compounds as hcv inhibitors
SG11201504749TA (en) 2012-12-21 2015-07-30 Abt Holding Co Benzazepines as serotonin 5-ht2c receptor ligands and uses thereof
CN105566262B (zh) * 2016-01-11 2017-10-27 华东理工大学 苯并呋喃‑7‑烷基胺类化合物及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4255445A (en) * 1980-03-07 1981-03-10 Smithkline Corporation 8-Hydroxy-6,7-(2-methyl-2,3-dihydrofuro)-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
CA1234110A (en) * 1983-08-12 1988-03-15 Joel G. Berger Benzazepine derivatives, pharmaceutical compositions containing them and processes for the preparation of such compounds and compositions
DK180485D0 (da) * 1985-04-22 1985-04-23 Novo Industri As Nitrogenholdige forbindelser
DK157925C (da) * 1985-04-22 1990-08-27 Novo Industri As 2,3,4,5-tetrahydro-1h-3-benzazepinderivater og farmaceutiske praeparater indeholdende disse

Also Published As

Publication number Publication date
ES2133542T3 (es) 1999-09-16
NO953543L (no) 1995-09-08
FI954229A (fi) 1995-09-08
AU6138694A (en) 1994-09-26
NO953543D0 (no) 1995-09-08
AU682494B2 (en) 1997-10-09
ZA941377B (en) 1995-08-28
NZ262098A (en) 1996-11-26
KR960701022A (ko) 1996-02-24
FI954229A0 (fi) 1995-09-08
US5512562A (en) 1996-04-30
CN1121710A (zh) 1996-05-01
IL108730A0 (en) 1994-05-30
DE69418321T2 (de) 1999-12-30
DK0688320T3 (da) 1999-11-01
JP3779319B2 (ja) 2006-05-24
JPH08507498A (ja) 1996-08-13
TW279861B (es) 1996-07-01
WO1994020472A1 (en) 1994-09-15
CA2157668A1 (en) 1994-09-15
FI111944B (fi) 2003-10-15
CA2157668C (en) 2006-05-30
GR3030864T3 (en) 1999-11-30
DE69418321D1 (de) 1999-06-10
ATE179700T1 (de) 1999-05-15
IL108730A (en) 1999-08-17
EP0688320B1 (en) 1999-05-06
EP0688320A1 (en) 1995-12-27
CN1045957C (zh) 1999-10-27

Similar Documents

Publication Publication Date Title
DK26793D0 (da) Benzofuranyl- eller dihydrobenzofuranyl-substituerede tricycliske benzazepiner, der anvendelse og fremstilling
EP1020445A4 (en) CONDENSED PYRIDE DERIVATIVES
MY136270A (en) Processes and intermediates for preparing anti-cancer compounds
UA66825C2 (uk) Азаполіциклічні сполуки, конденсовані з арилом, фармацевтична композиція, спосіб лікування та спосіб зниження нікотинової залежності
YU48322B (sh) Derivati alfa-aminokarboksamida supstituisani n-fenilalkilom i postupak za njihovo pripremanje
NO994452D0 (no) Substituerte 4-arylmetylen-2-imino-2,3-dihydrotiazoler og derivater, og deres farmasöytiske anvendelse
TW349098B (en) Naphthalene derivatives, process for the preparation thereof, and intermediates therefor
EA200000731A1 (ru) Альфа-аминоамидные производные, полезные в качестве анальгетических агентов
ES2117795T3 (es) Derivados de acetamida y su uso como modificadores del comportamiento de toma alimentaria.
ES2193158T3 (es) Compuestos tetraciclicos agonistas de la dopamina.
IS1446B6 (is) Ný díhýdróbenzófúran- og króman-karboxamíð efni, aðferð við framleiðslu þeirra og notkun þeirra semlyf
DE69412016D1 (de) Substituierte arylalkoxybenzyl-aminopropanamide, ihre herstellung und verwendung als antiepileptische, neuroprotektive und antidepressive mittel
HUP9904294A2 (hu) Topiramát származékok alkalmazása neuropátiás fájdalom kezelésére alkalmas gyógyszer előállítására
TR199900527T2 (xx) N�rolojik bozukluklar�n tedavisi i�in benzopiranollerin kullan�m�.
ES2075098T3 (es) Derivados de furano.
TW334428B (en) Novel benzodiazepine derivatives
DE60203937D1 (de) Herstellung von trans-kondensierte 3,3a,8,12b-tetrahydro-2h-dibenzo[3,4:6,7]cyclohepta[1,2-b]furan derivaten
EP0769496A4 (en) 2,3-DIHYDROBENZOFURAN DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF
CA2151503A1 (en) 2,3-Dihydrobenzofuran Derivatives
AU7134091A (en) N-cycloalkylalkylamines, their process of preparation, their use as a medicament and their synthesis intermediates

Legal Events

Date Code Title Description
A0 Application filed
AHS Application shelved for other reasons than non-payment