DK2658542T4 - Topisk lokaliseret isoxazolinformulering - Google Patents
Topisk lokaliseret isoxazolinformuleringInfo
- Publication number
- DK2658542T4 DK2658542T4 DK11813330.5T DK11813330T DK2658542T4 DK 2658542 T4 DK2658542 T4 DK 2658542T4 DK 11813330 T DK11813330 T DK 11813330T DK 2658542 T4 DK2658542 T4 DK 2658542T4
- Authority
- DK
- Denmark
- Prior art keywords
- topically
- formulation
- localized
- localized isoxazoline
- isoxazoline formulation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A61K9/0017—Non-human animal skin, e.g. pour-on, spot-on
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Zoology (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Agronomy & Crop Science (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10197089 | 2010-12-27 | ||
| US201161430240P | 2011-01-06 | 2011-01-06 | |
| PCT/EP2011/073828 WO2012089622A2 (en) | 2010-12-27 | 2011-12-22 | Topical localized isoxazoline formulation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK2658542T3 DK2658542T3 (da) | 2022-03-28 |
| DK2658542T4 true DK2658542T4 (da) | 2025-08-25 |
Family
ID=43971048
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK11813330.5T DK2658542T4 (da) | 2010-12-27 | 2011-12-22 | Topisk lokaliseret isoxazolinformulering |
Country Status (19)
| Country | Link |
|---|---|
| US (4) | US9173870B2 (enExample) |
| EP (1) | EP2658542B2 (enExample) |
| JP (3) | JP6002148B2 (enExample) |
| KR (2) | KR102027723B1 (enExample) |
| CN (2) | CN103260621B (enExample) |
| AU (2) | AU2016201954B2 (enExample) |
| BR (1) | BR112013015503A2 (enExample) |
| CA (1) | CA2822839C (enExample) |
| DK (1) | DK2658542T4 (enExample) |
| ES (1) | ES2908094T5 (enExample) |
| FI (1) | FI2658542T4 (enExample) |
| HU (1) | HUE058291T2 (enExample) |
| MX (2) | MX383895B (enExample) |
| NZ (1) | NZ611476A (enExample) |
| PL (1) | PL2658542T5 (enExample) |
| PT (1) | PT2658542T (enExample) |
| RU (2) | RU2749733C2 (enExample) |
| WO (1) | WO2012089622A2 (enExample) |
| ZA (1) | ZA201304514B (enExample) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103260621B (zh) * | 2010-12-27 | 2016-08-24 | 英特维特国际股份有限公司 | 外用局部异噁唑啉制剂 |
| EP2658541B2 (en) * | 2010-12-27 | 2025-12-17 | Intervet International B.V. | Topical localized isoxazoline formulation comprising glycofurol |
| SG11201400558YA (en) | 2011-09-12 | 2014-04-28 | Merial Ltd | Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof |
| SMT201900083T1 (it) | 2012-02-06 | 2019-02-28 | Merial Inc | Composizioni veterinarie orali parassiticide comprendenti principi attivi che agiscono per via sistematica, loro metodi e loro usi |
| JO3626B1 (ar) | 2012-02-23 | 2020-08-27 | Merial Inc | تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها |
| AU2013245011B2 (en) | 2012-04-04 | 2017-11-23 | Intervet International B.V. | Solid oral pharmaceutical compositions for isoxazoline compounds |
| DK3063144T3 (da) | 2013-11-01 | 2021-10-25 | Boehringer Ingelheim Animal Health Usa Inc | Antiparasitære og pesticid-isoxazolinforbindelser |
| CN105979944A (zh) | 2013-12-20 | 2016-09-28 | 英特维特国际股份有限公司 | 异噁唑啉衍生物用于治疗或预防家禽中的节肢动物侵袭的用途 |
| CN110327468B (zh) | 2013-12-20 | 2023-04-28 | 英特维特国际股份有限公司 | 异噁唑啉组合物及其在预防或治疗动物的寄生虫侵袭中的用途 |
| MX378055B (es) | 2014-04-17 | 2025-03-10 | Boehringer Ingelheim Animal Health Usa Inc | Uso de compuestos de malononitrilo para proteger animales de parásitos. |
| WO2016022066A1 (en) | 2014-08-04 | 2016-02-11 | Jerry Tan Eye Surgery Pte Ltd | Pharmaceutical compositions for demodex related blepharitis and eyelid crusting |
| PL3236960T3 (pl) | 2014-12-22 | 2025-07-07 | Intervet International B.V. | Fluralaner do zastosowania w leczeniu demodekozy |
| UY36570A (es) | 2015-02-26 | 2016-10-31 | Merial Inc | Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas |
| UY36683A (es) | 2015-05-20 | 2016-12-30 | Merial Inc | Compuestos depsipeptídicos como anthelmínticos |
| US20170333305A1 (en) * | 2016-05-23 | 2017-11-23 | Microban Products Company | Topical skin product having retention property |
| US10653144B2 (en) | 2016-10-14 | 2020-05-19 | Boehringer Ingelheim Animal Health USA Inc. | Pesticidal and parasiticidal vinyl isoxazoline compounds |
| CA3044038A1 (en) | 2016-11-16 | 2018-05-24 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic depsipeptide compounds |
| JP2020530850A (ja) | 2017-08-14 | 2020-10-29 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | 殺有害生物および殺寄生生物ピラゾール−イソキサゾリン化合物 |
| WO2019101961A1 (en) * | 2017-11-23 | 2019-05-31 | Ceva Sante Animale | Composition containing moxidectin for treating parasites infestations |
| KR20250057155A (ko) | 2017-12-15 | 2025-04-28 | 타르서스 파마수티칼스, 아이엔씨. | 안검염을 치료하기 위한 이속사졸린 구충제 제제 및 방법 |
| AR113997A1 (es) * | 2017-12-21 | 2020-07-08 | Intervet Int Bv | Composiciones antiparasitarias para unción dorsal continua |
| MX2021000293A (es) | 2018-07-09 | 2021-07-15 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos heterociclicos antihelminticos. |
| EP3883648A1 (en) | 2018-11-20 | 2021-09-29 | Boehringer Ingelheim Animal Health USA Inc. | Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof |
| KR102079347B1 (ko) * | 2018-11-30 | 2020-02-19 | 문현규 | 치과용 유닛 체어 |
| BR112021018631A2 (pt) | 2019-03-19 | 2021-11-23 | Boehringer Ingelheim Animal Health Usa Inc | Compostos anti-helmínticos de aza-benzotiofeno e aza-benzofurano |
| EP3962448A1 (en) * | 2019-05-03 | 2022-03-09 | Intervet International B.V. | Injectable pharmaceutical compositions and uses thereof |
| FR3107531B1 (fr) * | 2020-02-20 | 2022-02-25 | Rl Innovation | .composition liquide ou en gel, ecologique permettant l’enlevement des graffittis, chewing-gums, colles, resines sur tous supports poreux ou non ainsi que tous marquages routier |
| JP2023528822A (ja) | 2020-05-29 | 2023-07-06 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | 駆虫性複素環式化合物 |
| WO2022020585A1 (en) | 2020-07-24 | 2022-01-27 | Elanco Us Inc. | Process for making an isoxazoline compound and intermediate thereof |
| CH717763A2 (de) | 2020-08-18 | 2022-02-28 | Swibox Ag | Abzweigsystem für elektrische Leiter. |
| US20240116854A1 (en) | 2021-01-27 | 2024-04-11 | Intervet Inc. | Cyclopropylamide compounds against parasites in fish |
| WO2022162016A1 (en) | 2021-01-27 | 2022-08-04 | Intervet International B.V. | Cyclopropylamide compounds against parasites in fish |
| CN118715163A (zh) | 2022-02-17 | 2024-09-27 | 勃林格殷格翰动物保健有限公司 | 用于提供流体制品邮寄封的方法和系统 |
| NO20240925A1 (en) | 2023-09-15 | 2025-03-17 | Evah Atlantic Inc | Dihydroisoxazole compound for use in reducing ectoparasite infestations on fish |
| WO2025191150A2 (en) | 2024-03-15 | 2025-09-18 | Krka, D.D., Novo Mesto | Stable isoxazoline formulation for topical application to the skin |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3950360A (en) | 1972-06-08 | 1976-04-13 | Sankyo Company Limited | Antibiotic substances |
| US3984564A (en) | 1972-06-08 | 1976-10-05 | Sankyo Company Limited | Antibiotic substances B-41, their production and their use as insecticides and acaricides |
| JPS60218303A (ja) | 1984-04-13 | 1985-11-01 | Mitsubishi Chem Ind Ltd | 忌避剤組成物 |
| US4916154A (en) | 1986-09-12 | 1990-04-10 | American Cyanamid Company | 23-Imino derivatives of LL-F28249 compounds |
| IL98599A (en) | 1990-06-28 | 1995-06-29 | Merck & Co Inc | Stable salts of 4"-deoxy-4"-epi-methylamino avermectin b1a/b1b and insecticidal compositions containing them |
| JPH04217606A (ja) * | 1990-11-30 | 1992-08-07 | Mitsubishi Gas Chem Co Inc | 吸血害虫の吸血阻害剤 |
| US5874479A (en) | 1991-03-01 | 1999-02-23 | Warner-Lambert Company | Therapeutic permeation enhanced-wound healing compositions and methods for preparing and using same |
| US5399717A (en) | 1993-09-29 | 1995-03-21 | Merck & Co., Inc. | Glycosidation route to 4"-epi-methylamino-4"-deoxyavermectin B1 |
| US7906128B2 (en) * | 2002-10-21 | 2011-03-15 | Wyeth Llc | Use of neuronal sodium channel antagonists for the control of ectoparasites in homeothermic animals |
| US8119150B2 (en) * | 2002-10-25 | 2012-02-21 | Foamix Ltd. | Non-flammable insecticide composition and uses thereof |
| CN1826170B (zh) | 2003-07-18 | 2010-12-08 | 巴克斯特国际公司 | 通过受控相分离制备的小球形颗粒的制造方法、其用途和成分 |
| US7422215B2 (en) | 2003-10-08 | 2008-09-09 | Seven Generations, Inc. | Biased card deal |
| RS53639B1 (sr) | 2004-03-05 | 2015-04-30 | Nissan Chemical Industries Ltd. | Izoksazolinom supstituisano benzamidno jedinjenje i sredstvo za kontrolu štetnih organizama |
| TWI350728B (en) * | 2004-10-08 | 2011-10-21 | Wyeth Corp | Amitraz compositions |
| CN100566566C (zh) * | 2004-10-08 | 2009-12-09 | 惠氏公司 | 三亚螨（amitraz）组合物 |
| US7749527B2 (en) | 2005-05-24 | 2010-07-06 | Wyeth Llc | Gel compositions for control of ecto-parasites |
| TWI368505B (en) | 2005-05-24 | 2012-07-21 | Wyeth Corp | Versatile high load concentrate compositions for control of ecto-parasites |
| US20060293260A1 (en) | 2005-05-24 | 2006-12-28 | Wyeth | Useful high load concentrate compositions for control of ecto-and endo-parasites |
| TWI412322B (zh) | 2005-12-30 | 2013-10-21 | Du Pont | 控制無脊椎害蟲之異唑啉 |
| EP2022776A4 (en) | 2006-05-31 | 2009-10-21 | Univ Hokkaido Nat Univ Corp | FLUOROAMINES COMPRISING A PERFLUOROALKYL GROUP, PROCESS FOR PRODUCTION THEREOF, FLUOROAMINE FLUORINATION METHOD AND METHOD FOR RECOVERING AN AMIDE COMPRISING A PERFLUOROALKYL GROUP |
| TW200846029A (en) | 2007-02-09 | 2008-12-01 | Wyeth Corp | High dose, long-acting ectoparasiticide for extended control |
| CL2008001614A1 (es) | 2007-06-05 | 2008-08-08 | Wyeth Corp | Composicion parasiticida veterinaria que comprende un disolvente que no contiene hidroxilo, un estabilizador, amitraz y opcionalmente una lactona macrociclica y miristato de isopropilo; y su uso para tratar o controlar una infestacion o infeccion par |
| TWI430995B (zh) | 2007-06-26 | 2014-03-21 | Du Pont | 萘異唑啉無脊椎有害動物控制劑 |
| HUE037127T2 (hu) | 2007-06-27 | 2018-08-28 | Du Pont | Állati károkozó irtására szolgáló eljárás |
| TWI556741B (zh) * | 2007-08-17 | 2016-11-11 | 英特威特國際股份有限公司 | 異唑啉組成物及其作為抗寄生蟲藥上的應用 |
| US8377942B2 (en) | 2008-12-18 | 2013-02-19 | Novartis Ag | Isoxazolines derivatives and their use as pesticide |
| RU2518462C2 (ru) | 2008-12-19 | 2014-06-10 | Новартис Аг | Органические соединения |
| BRPI1008403A2 (pt) | 2009-02-23 | 2015-08-25 | Wyeth Llc | Formulação ectoparasiticida de odor melhorado |
| WO2011075591A1 (en) | 2009-12-17 | 2011-06-23 | Merial Limited | Anti parasitic dihydroazole compounds and compositions comprising same |
| CN101780020B (zh) * | 2010-02-09 | 2011-12-28 | 广东名臣有限公司 | 一种清凉、止痒、驱蚊的花露水 |
| MX2012011549A (es) | 2010-04-08 | 2013-01-29 | Ah Usa 42 Llc | Derivados de 3,5-difenil-isoxazolina sustituida como insecticidas y acaricidas. |
| EP2658541B2 (en) | 2010-12-27 | 2025-12-17 | Intervet International B.V. | Topical localized isoxazoline formulation comprising glycofurol |
| CN103260621B (zh) * | 2010-12-27 | 2016-08-24 | 英特维特国际股份有限公司 | 外用局部异噁唑啉制剂 |
| WO2018039508A1 (en) | 2016-08-25 | 2018-03-01 | Merial, Inc. | Method for reducing unwanted effects in parasiticidal treatments |
-
2011
- 2011-12-22 CN CN201180062852.8A patent/CN103260621B/zh active Active
- 2011-12-22 JP JP2013545416A patent/JP6002148B2/ja active Active
- 2011-12-22 KR KR1020187032742A patent/KR102027723B1/ko active Active
- 2011-12-22 CN CN201610036739.7A patent/CN105616406B/zh active Active
- 2011-12-22 NZ NZ611476A patent/NZ611476A/en unknown
- 2011-12-22 CA CA2822839A patent/CA2822839C/en active Active
- 2011-12-22 US US13/996,263 patent/US9173870B2/en active Active
- 2011-12-22 EP EP11813330.5A patent/EP2658542B2/en active Active
- 2011-12-22 PT PT118133305T patent/PT2658542T/pt unknown
- 2011-12-22 MX MX2018007542A patent/MX383895B/es unknown
- 2011-12-22 FI FIEP11813330.5T patent/FI2658542T4/fi active
- 2011-12-22 RU RU2017118161A patent/RU2749733C2/ru active
- 2011-12-22 RU RU2013135280A patent/RU2633061C2/ru active
- 2011-12-22 KR KR1020137016602A patent/KR20130130761A/ko not_active Ceased
- 2011-12-22 ES ES11813330T patent/ES2908094T5/es active Active
- 2011-12-22 DK DK11813330.5T patent/DK2658542T4/da active
- 2011-12-22 HU HUE11813330A patent/HUE058291T2/hu unknown
- 2011-12-22 BR BR112013015503A patent/BR112013015503A2/pt not_active Application Discontinuation
- 2011-12-22 PL PL11813330.5T patent/PL2658542T5/pl unknown
- 2011-12-22 WO PCT/EP2011/073828 patent/WO2012089622A2/en not_active Ceased
- 2011-12-22 MX MX2013007500A patent/MX356926B/es active IP Right Grant
-
2013
- 2013-06-19 ZA ZA2013/04514A patent/ZA201304514B/en unknown
-
2015
- 2015-09-28 US US14/867,641 patent/US9532978B2/en active Active
-
2016
- 2016-03-30 AU AU2016201954A patent/AU2016201954B2/en active Active
- 2016-07-14 JP JP2016139272A patent/JP6246864B2/ja active Active
- 2016-11-22 US US15/359,036 patent/US20170071914A1/en not_active Abandoned
-
2017
- 2017-10-30 AU AU2017254818A patent/AU2017254818B2/en active Active
- 2017-11-10 JP JP2017217049A patent/JP6514754B2/ja active Active
- 2017-11-21 US US15/819,523 patent/US10864195B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK2658542T4 (da) | Topisk lokaliseret isoxazolinformulering | |
| PT2658541T (pt) | Formulação de isoxazolina localizada tópica compreendendo glicofurol | |
| PL2611310T3 (pl) | Formulacja antybakteryjna | |
| DK3053932T3 (da) | Hidtil ukendte ctla4-ig-immunoadhesiner | |
| FI20105284L (fi) | Sekoitin | |
| SMT201500291B (it) | Nuovi agenti antimalarici | |
| IL226307A0 (en) | Compounds and methods for treating pain | |
| BR112012028556A2 (pt) | Indóis | |
| CR20130111A (es) | Triazina-oxidiazoles | |
| DK2525798T3 (da) | Anæstetisk formulering | |
| DK2654736T3 (da) | Hidtil ukendt farmaceutisk sammensætning | |
| EP2552212A4 (en) | IMPROVED FORMULATION | |
| BRPI1009465A2 (pt) | Formulação | |
| DK3072505T3 (da) | Testosteronformuleringer | |
| EP2531023A4 (en) | IMPROVED FORMULATION | |
| BR112014000015A2 (pt) | formulação | |
| DK2343051T3 (da) | Anti-cancer formulering | |
| PL2635269T3 (pl) | Kompozycja złożona | |
| DK2868318T4 (da) | Injicerbar formulering | |
| EP2770828A4 (en) | FORMULATION | |
| CO6801789A2 (es) | N-hetarilmetil pirazolilcarboxamidas | |
| SMT201400194B (it) | Complesso di flurano | |
| FR2957260B1 (fr) | Nouvelle formulation dermocorticoide | |
| ITGE20110047A1 (it) | Miscelatore | |
| FR2967069B3 (fr) | Formulations |