DK2658542T4 - Topisk lokaliseret isoxazolinformulering - Google Patents

Topisk lokaliseret isoxazolinformulering

Info

Publication number
DK2658542T4
DK2658542T4 DK11813330.5T DK11813330T DK2658542T4 DK 2658542 T4 DK2658542 T4 DK 2658542T4 DK 11813330 T DK11813330 T DK 11813330T DK 2658542 T4 DK2658542 T4 DK 2658542T4
Authority
DK
Denmark
Prior art keywords
topically
formulation
localized
localized isoxazoline
isoxazoline formulation
Prior art date
Application number
DK11813330.5T
Other languages
Danish (da)
English (en)
Other versions
DK2658542T3 (da
Inventor
Stefan Fuchs
Anja Regina Heckeroth
Ramona Müller
Heike Williams
Hartmut Zoller
Original Assignee
Intervet Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43971048&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2658542(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Intervet Int Bv filed Critical Intervet Int Bv
Publication of DK2658542T3 publication Critical patent/DK2658542T3/da
Application granted granted Critical
Publication of DK2658542T4 publication Critical patent/DK2658542T4/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • A61K9/0017Non-human animal skin, e.g. pour-on, spot-on
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK11813330.5T 2010-12-27 2011-12-22 Topisk lokaliseret isoxazolinformulering DK2658542T4 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10197089 2010-12-27
US201161430240P 2011-01-06 2011-01-06
PCT/EP2011/073828 WO2012089622A2 (en) 2010-12-27 2011-12-22 Topical localized isoxazoline formulation

Publications (2)

Publication Number Publication Date
DK2658542T3 DK2658542T3 (da) 2022-03-28
DK2658542T4 true DK2658542T4 (da) 2025-08-25

Family

ID=43971048

Family Applications (1)

Application Number Title Priority Date Filing Date
DK11813330.5T DK2658542T4 (da) 2010-12-27 2011-12-22 Topisk lokaliseret isoxazolinformulering

Country Status (19)

Country Link
US (4) US9173870B2 (OSRAM)
EP (1) EP2658542B2 (OSRAM)
JP (3) JP6002148B2 (OSRAM)
KR (2) KR102027723B1 (OSRAM)
CN (2) CN103260621B (OSRAM)
AU (2) AU2016201954B2 (OSRAM)
BR (1) BR112013015503A2 (OSRAM)
CA (1) CA2822839C (OSRAM)
DK (1) DK2658542T4 (OSRAM)
ES (1) ES2908094T5 (OSRAM)
FI (1) FI2658542T4 (OSRAM)
HU (1) HUE058291T2 (OSRAM)
MX (2) MX383895B (OSRAM)
NZ (1) NZ611476A (OSRAM)
PL (1) PL2658542T5 (OSRAM)
PT (1) PT2658542T (OSRAM)
RU (2) RU2633061C2 (OSRAM)
WO (1) WO2012089622A2 (OSRAM)
ZA (1) ZA201304514B (OSRAM)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101992589B1 (ko) * 2010-12-27 2019-06-24 인터벳 인터내셔널 비.브이. 글리코푸롤을 포함하는 국소 적용 이속사졸린 제제
CN103260621B (zh) * 2010-12-27 2016-08-24 英特维特国际股份有限公司 外用局部异噁唑啉制剂
PH12014500537A1 (en) 2011-09-12 2014-04-21 Merial Inc Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof
SG11201404595TA (en) 2012-02-06 2014-09-26 Merial Ltd Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
WO2013150055A1 (en) 2012-04-04 2013-10-10 Intervet International B.V. Solid oral pharmaceutical compositions for isoxazoline compounds
AP2016009184A0 (en) 2013-11-01 2016-04-30 Merial Ltd Antiparisitic and pesticidal isoxazoline compounds
JP6581586B2 (ja) 2013-12-20 2019-09-25 インターベット インターナショナル ベー. フェー. イソオキサゾリン組成物および動物における寄生虫侵襲の予防または処置におけるその使用
MX376210B (es) 2013-12-20 2025-03-07 Intervet Int Bv Uso de derivados de isoxazolina para el tratamiento o prevención de infestaciones por artrópodos en aves de corral.
AU2015247463B2 (en) 2014-04-17 2018-03-29 Basf, Se Use of malononitrile compounds for protecting animals from parasites
WO2016022066A1 (en) 2014-08-04 2016-02-11 Jerry Tan Eye Surgery Pte Ltd Pharmaceutical compositions for demodex related blepharitis and eyelid crusting
PL3236960T3 (pl) 2014-12-22 2025-07-07 Intervet International B.V. Fluralaner do zastosowania w leczeniu demodekozy
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
HRP20211041T1 (hr) 2015-05-20 2021-10-01 Boehringer Ingelheim Animal Health USA Inc. Anthelmintski depsipeptidni spojevi
US20170333305A1 (en) * 2016-05-23 2017-11-23 Microban Products Company Topical skin product having retention property
CA3040278A1 (en) 2016-10-14 2018-04-19 Boehringer Ingelheim Animal Health USA Inc. Pesticidal and parasiticidal vinyl isoxazoline compounds
JP2020504710A (ja) 2016-11-16 2020-02-13 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 駆虫性デプシペプチド化合物
ES2944616T3 (es) 2017-08-14 2023-06-22 Boehringer Ingelheim Animal Health Usa Inc Compuestos de pirazol-isoxazolina plaguicidas y parasiticidas
KR20200090165A (ko) * 2017-11-23 2020-07-28 세바 상뜨 아니말르 기생충 감염 치료용 목시텍틴 함유 조성물
KR20250065422A (ko) 2017-12-15 2025-05-12 타르서스 파마수티칼스, 아이엔씨. 안검염을 치료하기 위한 이속사졸린 구충제 제제 및 방법
AR113997A1 (es) 2017-12-21 2020-07-08 Intervet Int Bv Composiciones antiparasitarias para unción dorsal continua
WO2020014068A1 (en) 2018-07-09 2020-01-16 Boehringer Ingelheim Animal Health USA Inc. Anthelminthic heterocyclic compounds
US11773066B2 (en) 2018-11-20 2023-10-03 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof
KR102079347B1 (ko) * 2018-11-30 2020-02-19 문현규 치과용 유닛 체어
CA3133100A1 (en) 2019-03-19 2020-09-24 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic aza-benzothiophene and aza-benzofuran compounds
BR112021021649A2 (pt) * 2019-05-03 2021-12-21 Intervet Int Bv Composições farmacêuticas injetáveis e usos das mesmas
EP4077286A1 (en) 2019-12-18 2022-10-26 Elanco Tiergesundheit AG Isoxazoline derivatives as pesticides
FR3107531B1 (fr) * 2020-02-20 2022-02-25 Rl Innovation .composition liquide ou en gel, ecologique permettant l’enlevement des graffittis, chewing-gums, colles, resines sur tous supports poreux ou non ainsi que tous marquages routier
AU2021278889A1 (en) 2020-05-29 2023-02-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Anthelmintic heterocyclic compounds
WO2022020585A1 (en) 2020-07-24 2022-01-27 Elanco Us Inc. Process for making an isoxazoline compound and intermediate thereof
CH717763A2 (de) 2020-08-18 2022-02-28 Swibox Ag Abzweigsystem für elektrische Leiter.
US20240116854A1 (en) 2021-01-27 2024-04-11 Intervet Inc. Cyclopropylamide compounds against parasites in fish
JP2024511258A (ja) 2021-01-27 2024-03-13 コルテバ アグリサイエンス エルエルシー 魚における寄生生物に対するシクロプロピルアミド化合物
CN118715163A (zh) 2022-02-17 2024-09-27 勃林格殷格翰动物保健有限公司 用于提供流体制品邮寄封的方法和系统
NO20240925A1 (en) 2023-09-15 2025-03-17 Evah Atlantic Inc Dihydroisoxazole compound for use in reducing ectoparasite infestations on fish
WO2025191150A2 (en) 2024-03-15 2025-09-18 Krka, D.D., Novo Mesto Stable isoxazoline formulation for topical application to the skin

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3984564A (en) 1972-06-08 1976-10-05 Sankyo Company Limited Antibiotic substances B-41, their production and their use as insecticides and acaricides
US3950360A (en) 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
JPS60218303A (ja) 1984-04-13 1985-11-01 Mitsubishi Chem Ind Ltd 忌避剤組成物
US4916154A (en) 1986-09-12 1990-04-10 American Cyanamid Company 23-Imino derivatives of LL-F28249 compounds
IL98599A (en) 1990-06-28 1995-06-29 Merck & Co Inc Stable salts of 4"-deoxy-4"-epi-methylamino avermectin b1a/b1b and insecticidal compositions containing them
JPH04217606A (ja) * 1990-11-30 1992-08-07 Mitsubishi Gas Chem Co Inc 吸血害虫の吸血阻害剤
US5874479A (en) 1991-03-01 1999-02-23 Warner-Lambert Company Therapeutic permeation enhanced-wound healing compositions and methods for preparing and using same
US5399717A (en) 1993-09-29 1995-03-21 Merck & Co., Inc. Glycosidation route to 4"-epi-methylamino-4"-deoxyavermectin B1
US7906128B2 (en) * 2002-10-21 2011-03-15 Wyeth Llc Use of neuronal sodium channel antagonists for the control of ectoparasites in homeothermic animals
US8119150B2 (en) * 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
JP2007531701A (ja) * 2003-07-18 2007-11-08 バクスター・インターナショナル・インコーポレイテッド 制御された相分離により調製される小球状粒子の作製方法、使用および組成物
US7422215B2 (en) 2003-10-08 2008-09-09 Seven Generations, Inc. Biased card deal
JP4883296B2 (ja) 2004-03-05 2012-02-22 日産化学工業株式会社 イソキサゾリン置換ベンズアミド化合物及び有害生物防除剤
CN100566566C (zh) * 2004-10-08 2009-12-09 惠氏公司 三亚螨(amitraz)组合物
PE20060785A1 (es) 2004-10-08 2006-09-19 Wyeth Corp Composiciones de amitraz
US7749527B2 (en) 2005-05-24 2010-07-06 Wyeth Llc Gel compositions for control of ecto-parasites
US20060293260A1 (en) 2005-05-24 2006-12-28 Wyeth Useful high load concentrate compositions for control of ecto-and endo-parasites
TWI368505B (en) 2005-05-24 2012-07-21 Wyeth Corp Versatile high load concentrate compositions for control of ecto-parasites
TWI412322B (zh) 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
WO2007139182A1 (ja) * 2006-05-31 2007-12-06 National University Corporation Hokkaido University パーフルオロアルキル基を有するフルオロアミン、その製造方法及びそれを用いるフッ素化方法、並びにパーフルオロアルキル基を有するアミドの回収方法
TW200846029A (en) 2007-02-09 2008-12-01 Wyeth Corp High dose, long-acting ectoparasiticide for extended control
CL2008001614A1 (es) 2007-06-05 2008-08-08 Wyeth Corp Composicion parasiticida veterinaria que comprende un disolvente que no contiene hidroxilo, un estabilizador, amitraz y opcionalmente una lactona macrociclica y miristato de isopropilo; y su uso para tratar o controlar una infestacion o infeccion par
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
LT2957284T (lt) 2007-06-27 2018-04-10 E. I. Du Pont De Nemours And Company Kovos su gyvūnų kenkėjais būdas
TWI556741B (zh) * 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
CA2747060A1 (en) 2008-12-18 2010-07-15 Novartis Ag Isoxazolines derivatives and their use as pesticide
PT2379537E (pt) 2008-12-19 2012-12-27 Novartis Ag Compostos orgânicos
BRPI1008403A2 (pt) * 2009-02-23 2015-08-25 Wyeth Llc Formulação ectoparasiticida de odor melhorado
EP2513104B1 (en) 2009-12-17 2016-03-16 Merial, Inc. Antiparasitic dihydroazole compounds and compositions comprising same
CN101780020B (zh) * 2010-02-09 2011-12-28 广东名臣有限公司 一种清凉、止痒、驱蚊的花露水
CN102933563A (zh) 2010-04-08 2013-02-13 Ah美国42有限责任公司 作为杀虫剂和杀螨剂的取代的3,5-二苯基异噁唑啉衍生物
KR101992589B1 (ko) 2010-12-27 2019-06-24 인터벳 인터내셔널 비.브이. 글리코푸롤을 포함하는 국소 적용 이속사졸린 제제
CN103260621B (zh) * 2010-12-27 2016-08-24 英特维特国际股份有限公司 外用局部异噁唑啉制剂
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments

Also Published As

Publication number Publication date
MX2013007500A (es) 2013-08-01
CN103260621B (zh) 2016-08-24
EP2658542B1 (en) 2022-01-26
DK2658542T3 (da) 2022-03-28
JP6246864B2 (ja) 2017-12-13
AU2017254818B2 (en) 2019-08-01
AU2016201954B2 (en) 2017-11-23
JP6514754B2 (ja) 2019-05-15
NZ611476A (en) 2015-10-30
MX383895B (es) 2025-03-14
US20130281501A1 (en) 2013-10-24
PT2658542T (pt) 2022-03-10
JP6002148B2 (ja) 2016-10-05
JP2018048194A (ja) 2018-03-29
BR112013015503A2 (pt) 2017-06-27
CA2822839A1 (en) 2012-07-05
AU2017254818A1 (en) 2017-11-16
PL2658542T3 (pl) 2022-06-20
US20160015689A1 (en) 2016-01-21
HUE058291T2 (hu) 2022-07-28
KR102027723B1 (ko) 2019-10-01
RU2017118161A3 (OSRAM) 2020-07-30
CN103260621A (zh) 2013-08-21
KR20180125037A (ko) 2018-11-21
AU2016201954A1 (en) 2016-04-21
FI2658542T4 (fi) 2025-09-02
RU2017118161A (ru) 2018-10-30
CA2822839C (en) 2020-12-29
ES2908094T3 (es) 2022-04-27
KR20130130761A (ko) 2013-12-02
US20180085352A1 (en) 2018-03-29
US10864195B2 (en) 2020-12-15
RU2749733C2 (ru) 2021-06-16
WO2012089622A3 (en) 2012-11-15
US9173870B2 (en) 2015-11-03
EP2658542B2 (en) 2025-06-04
JP2016222691A (ja) 2016-12-28
RU2013135280A (ru) 2015-02-10
CN105616406B (zh) 2019-12-13
AU2011351578A1 (en) 2013-06-20
EP2658542A2 (en) 2013-11-06
WO2012089622A2 (en) 2012-07-05
US9532978B2 (en) 2017-01-03
JP2014504586A (ja) 2014-02-24
ZA201304514B (en) 2014-03-26
PL2658542T5 (pl) 2025-07-28
CN105616406A (zh) 2016-06-01
ES2908094T5 (en) 2025-08-12
RU2633061C2 (ru) 2017-10-11
US20170071914A1 (en) 2017-03-16
MX356926B (es) 2018-06-19

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