DK2596119T3 - Fremgangsmåder til påvisning af sjældne subpopulationer af celler og stærkt oprensede sammensætninger af celler - Google Patents

Fremgangsmåder til påvisning af sjældne subpopulationer af celler og stærkt oprensede sammensætninger af celler Download PDF

Info

Publication number
DK2596119T3
DK2596119T3 DK11810518.8T DK11810518T DK2596119T3 DK 2596119 T3 DK2596119 T3 DK 2596119T3 DK 11810518 T DK11810518 T DK 11810518T DK 2596119 T3 DK2596119 T3 DK 2596119T3
Authority
DK
Denmark
Prior art keywords
cells
methods
highly purified
purified compositions
detecting rare
Prior art date
Application number
DK11810518.8T
Other languages
English (en)
Inventor
Irina Klimanskaya
Roger J Gay
Original Assignee
Astellas Inst For Regenerative Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Inst For Regenerative Medicine filed Critical Astellas Inst For Regenerative Medicine
Application granted granted Critical
Publication of DK2596119T3 publication Critical patent/DK2596119T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/42Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
DK11810518.8T 2010-07-23 2011-07-25 Fremgangsmåder til påvisning af sjældne subpopulationer af celler og stærkt oprensede sammensætninger af celler DK2596119T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36703810P 2010-07-23 2010-07-23
US41477010P 2010-11-17 2010-11-17
PCT/US2011/045232 WO2012012803A2 (en) 2010-07-23 2011-07-25 Methods for detection of rare subpopulations of cells and highly purified compositions of cells

Publications (1)

Publication Number Publication Date
DK2596119T3 true DK2596119T3 (da) 2021-07-26

Family

ID=45497502

Family Applications (1)

Application Number Title Priority Date Filing Date
DK11810518.8T DK2596119T3 (da) 2010-07-23 2011-07-25 Fremgangsmåder til påvisning af sjældne subpopulationer af celler og stærkt oprensede sammensætninger af celler

Country Status (11)

Country Link
US (2) US11739366B2 (da)
EP (2) EP3875599A1 (da)
JP (5) JP6184865B2 (da)
AU (1) AU2011280878B2 (da)
CA (1) CA2806127C (da)
DK (1) DK2596119T3 (da)
ES (1) ES2874953T3 (da)
HU (1) HUE054517T2 (da)
PL (1) PL2596119T3 (da)
PT (1) PT2596119T (da)
WO (1) WO2012012803A2 (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7794704B2 (en) 2004-01-23 2010-09-14 Advanced Cell Technology, Inc. Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration
WO2005070011A2 (en) 2004-01-23 2005-08-04 Advanced Cell Technology, Inc. Improved modalities for the treatment of degenerative diseases of the retina
AU2008312007A1 (en) 2007-10-12 2009-04-23 Advanced Cell Technology, Inc. Improved methods of producing RPE cells and compositions of RPE cells
JP6276918B2 (ja) 2009-11-12 2018-02-07 テクニオン リサーチ アンド ディベロップメント ファウンデーション リミテッド 多能性幹細胞を未分化状態で培養する培地、細胞培養および方法
KR102073730B1 (ko) 2009-11-17 2020-02-05 아스텔라스 인스티튜트 포 리제너러티브 메디슨 인간 rpe 세포의 생산 방법 및 인간 rpe 세포의 제약 제제
US11739366B2 (en) 2010-07-23 2023-08-29 Astellas Institute For Regenerative Medicine Methods for detection of rare subpopulations of cells and highly purified compositions of cells
CA2855941A1 (en) * 2011-11-14 2013-05-23 Advanced Cell Technology, Inc. Pharmaceutical preparations of human rpe cells and uses thereof
SI2788472T1 (sl) * 2011-12-06 2019-04-30 Astellas Institute For Regenerative Medicine Način usmerjene diferencijacije, produciranja endotelijskih celic roženice
JP6090735B2 (ja) * 2012-03-02 2017-03-08 国立大学法人山口大学 消化器系がん幹細胞を培養するための無血清培地、及びそれを用いた消化器系がん幹細胞の増殖方法
KR101906756B1 (ko) * 2012-10-09 2018-12-05 산바이오 인코포레이티드 망막 변성의 치료 방법 및 치료용 조성물
CA2908241C (en) * 2013-03-29 2021-09-07 Mie University Vital stain
US10352859B2 (en) * 2013-09-26 2019-07-16 Konica Minolta, Inc. Method for determining quantity of biological material in tissue section
EP3155092B1 (en) * 2014-06-10 2024-02-28 polybiocept GmbH Culture medium for cellular immunotherapy
JP6271407B2 (ja) * 2014-12-17 2018-01-31 富士フイルム株式会社 細胞評価統合方法
JP6459568B2 (ja) * 2015-01-30 2019-01-30 コニカミノルタ株式会社 目的細胞の検出方法および目的細胞検出システム
CN104833805A (zh) * 2015-03-09 2015-08-12 武汉格蓝丽富科技有限公司 一种循环肿瘤细胞检测和鉴定试剂盒及其应用
IL293110B2 (en) 2015-03-23 2023-11-01 Astellas Inst For Regenerative Medicine Improved assays for the potential of retinal pigment epithelium (RPE) cells and photoreceptor progenitors
TWI772270B (zh) 2015-08-18 2022-08-01 美商安斯泰來再生醫藥協會 臨床調配物
WO2017100498A1 (en) 2015-12-11 2017-06-15 The Johns Hopkins University Isolation of fusion-competent myoblasts and therapeutic applications thereof related to muscular dystrophy
CN106053196B (zh) * 2016-05-23 2019-02-15 无锡帝科电子材料股份有限公司 一种光伏正面银浆用银粉粒度测试的分散方法
CN106525541B (zh) * 2016-09-20 2019-01-18 广东东阳光药业有限公司 一种鲜冬虫夏草细胞活力的检测方法
CN110506109B (zh) 2017-06-05 2024-03-12 泰尔茂株式会社 细胞培养物的制造方法
JPWO2020067438A1 (ja) 2018-09-27 2021-08-30 国立大学法人大阪大学 多能性幹細胞由来細胞のシート化方法
KR102224273B1 (ko) * 2019-10-10 2021-03-08 고려대학교 산학협력단 줄기세포 유래 성숙 심근세포 및 이를 이용한 심혈관 질환 모델
CN114981417A (zh) 2019-10-30 2022-08-30 安斯泰来再生医药协会 生产视网膜色素上皮细胞的方法
CN112461807B (zh) * 2020-11-26 2021-11-19 山西大学 碳量子点在靶向细胞核仁免洗成像中的应用

Family Cites Families (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7A (en) 1836-08-10 Thomas blanchard
US5610753A (en) 1991-12-12 1997-03-11 Eastman Kodak Company Optical design of laser scanner to reduce thermal sensitivity
DE19609838A1 (de) * 1996-03-13 1997-09-18 Boehringer Mannheim Gmbh Verfahren und Teststreifen zur Bestimmung eines Analyten
FR2754544B1 (fr) 1996-10-10 1998-11-06 Lorraine Laminage Tole aluminiee a faible emissivite
US6440933B1 (en) 1997-09-10 2002-08-27 University Of Florida Compounds and method for the prevention and treatment of diabetic retinopathy
JP3880795B2 (ja) 1997-10-23 2007-02-14 ジェロン・コーポレーション フィーダー細胞を含まない培養物中で、霊長類由来始原幹細胞を増殖させるための方法
US6322901B1 (en) 1997-11-13 2001-11-27 Massachusetts Institute Of Technology Highly luminescent color-selective nano-crystalline materials
WO1999045094A1 (en) * 1998-03-02 1999-09-10 Compucyte Corp. Selective cell analysis
US6667176B1 (en) 2000-01-11 2003-12-23 Geron Corporation cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells
US6943153B1 (en) 1999-03-15 2005-09-13 The Regents Of The University Of California Use of recombinant gene delivery vectors for treating or preventing diseases of the eye
US6331313B1 (en) 1999-10-22 2001-12-18 Oculex Pharmaceticals, Inc. Controlled-release biocompatible ocular drug delivery implant devices and methods
US20080194022A1 (en) 2000-08-03 2008-08-14 Clarke Michael F Isolation and use of solid tumor stem cells
US8044259B2 (en) 2000-08-03 2011-10-25 The Regents Of The University Of Michigan Determining the capability of a test compound to affect solid tumor stem cells
US6984522B2 (en) 2000-08-03 2006-01-10 Regents Of The University Of Michigan Isolation and use of solid tumor stem cells
US6649138B2 (en) 2000-10-13 2003-11-18 Quantum Dot Corporation Surface-modified semiconductive and metallic nanoparticles having enhanced dispersibility in aqueous media
AU2002236495B2 (en) 2000-11-29 2006-05-11 Allergan, Inc. Intraocular implants for preventing transplant rejection in the eye
US6576291B2 (en) 2000-12-08 2003-06-10 Massachusetts Institute Of Technology Preparation of nanocrystallites
US20020083888A1 (en) 2000-12-28 2002-07-04 Zehnder Donald A. Flow synthesis of quantum dot nanocrystals
WO2002062201A2 (en) 2001-02-02 2002-08-15 Dana-Farber Cancer Institute, Inc. Rare event detection system
JP3806694B2 (ja) * 2001-05-04 2006-08-09 バイオサイト インコーポレイテッド 急性冠状動脈症候群の診断マーカーおよびその使用方法
KR101073411B1 (ko) * 2001-07-12 2011-10-17 제론 코포레이션 인간 다분화능 줄기 세포로부터 제조된 심근 세포 계통의 세포
JP4567436B2 (ja) 2001-07-20 2010-10-20 ライフ テクノロジーズ コーポレーション 発光ナノ粒子およびそれらの調製方法
IL160351A0 (en) 2001-08-23 2004-07-25 Reliance Life Sciences Pvt Ltd ISOLATION OF INNER CELL MASS FOR THE ESTABLISHMENT OF HUMAN EMBRYONIC STEM CELL (hESC) LINES
EP1456374A4 (en) 2001-11-26 2005-08-17 Advanced Cell Tech Inc METHODS FOR THE PRODUCTION AND USE OF REPROGRAMME HUMAN SOMATIC CELL CORES AND AUTOLOGOUS AND ISOGENIC HUMAN STEM CELLS
AU2003235652A1 (en) 2002-01-15 2003-07-30 Advanced Cell Technology, Inc. Cloning b and t lymphocytes
US20040091936A1 (en) 2002-05-24 2004-05-13 Michael West Bank of stem cells for producing cells for transplantation having HLA antigens matching those of transplant recipients, and methods for making and using such a stem cell bank
AU2003302020B2 (en) * 2002-11-14 2008-01-31 Ethicon Endo-Surgery, Inc. Methods and devices for detecting tissue cells
CN101044404A (zh) 2003-03-03 2007-09-26 长冈实业株式会社 用于不同类型细胞检测和定量的方法和装置以及生物光盘在该检测和定量中的应用
CA2524350C (en) 2003-05-07 2015-04-14 Indiana University Research & Technology Corporation Alloyed semiconductor quantum dots and concentration-gradient alloyed quantum dots, series comprising the same and methods related thereto
US20050118713A1 (en) * 2003-05-12 2005-06-02 Nikolai Strelchenko Morula derived embryonic stem cells
KR100657891B1 (ko) 2003-07-19 2006-12-14 삼성전자주식회사 반도체 나노결정 및 그 제조방법
KR100569168B1 (ko) * 2003-08-08 2006-04-07 (주)아비코아생명공학연구소 조류 정원줄기세포의 배양방법 및 이에 의해 수득한 조류정원줄기세포
US7794704B2 (en) 2004-01-23 2010-09-14 Advanced Cell Technology, Inc. Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration
US20190282622A1 (en) 2004-01-23 2019-09-19 Astellas Institute For Regenerative Medicine Modalities for the treatment of degenerative diseases of the retina
WO2005070011A2 (en) 2004-01-23 2005-08-04 Advanced Cell Technology, Inc. Improved modalities for the treatment of degenerative diseases of the retina
GB2432846B (en) 2004-09-08 2009-12-30 Wisconsin Alumni Res Found Medium and culture of embryonic stem cells
US7893315B2 (en) * 2004-11-04 2011-02-22 Advanced Cell Technology, Inc. Derivation of embryonic stem cells and embryo-derived cells
AU2005304978A1 (en) 2004-11-04 2006-05-18 Advanced Cell Technology, Inc. Derivation of embryonic stem cells
JP5129149B2 (ja) 2005-10-31 2013-01-23 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 癌を処置および診断するための組成物および方法
US20070160974A1 (en) 2006-01-10 2007-07-12 South Eastern Sydney And Illawarra Area Health Service Human embryonic stem cell clones
CZ301148B6 (cs) * 2006-01-25 2009-11-18 Univerzita Karlova V Praze Zpusob pestování lidských mezenchymových kmenových bunek, zejména pro lécbu nehojících se fraktur, a bioreaktor k provádení tohoto zpusobu
CA2646127A1 (en) 2006-03-16 2007-09-27 Health Research Inc. Inhibition of breast carcinoma stem cell growth and metastasis
KR100832592B1 (ko) 2006-08-17 2008-05-27 박현숙 폴리머 막을 이용한 줄기세포와 피더세포의 공배양방법
CA2675521C (en) 2007-01-22 2016-04-26 Raven Biotechnologies Human cancer stem cells
WO2008121437A2 (en) * 2007-02-08 2008-10-09 The Burnham Institute For Medical Research Trophinin-binding peptides and uses thereof
EP2886646B1 (en) 2007-04-18 2019-08-14 Hadasit Medical Research Services & Development Limited Stem cell-derived retinal pigment epithelial cells
JP2008307007A (ja) * 2007-06-15 2008-12-25 Bayer Schering Pharma Ag 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞
AU2008312007A1 (en) 2007-10-12 2009-04-23 Advanced Cell Technology, Inc. Improved methods of producing RPE cells and compositions of RPE cells
HU0700675D0 (en) * 2007-10-15 2007-12-28 Mta Tamogatott Kutatohelyek Ir Method for monitoring stem cell differentiation
US20090123439A1 (en) * 2007-11-09 2009-05-14 The Jackson Laboratory Diagnostic and prognosis methods for cancer stem cells
US20090233324A1 (en) 2008-03-11 2009-09-17 Kopf-Sill Anne R Methods for Diagnosing Cancer Using Samples Collected From A Central Vein Location or an Arterial Location
KR102073730B1 (ko) 2009-11-17 2020-02-05 아스텔라스 인스티튜트 포 리제너러티브 메디슨 인간 rpe 세포의 생산 방법 및 인간 rpe 세포의 제약 제제
US11739366B2 (en) 2010-07-23 2023-08-29 Astellas Institute For Regenerative Medicine Methods for detection of rare subpopulations of cells and highly purified compositions of cells
US20120258451A1 (en) 2011-04-08 2012-10-11 Advanced Cell Technology, Inc. Laser isolation of viable cells
CA2855941A1 (en) 2011-11-14 2013-05-23 Advanced Cell Technology, Inc. Pharmaceutical preparations of human rpe cells and uses thereof
IL293110B2 (en) 2015-03-23 2023-11-01 Astellas Inst For Regenerative Medicine Improved assays for the potential of retinal pigment epithelium (RPE) cells and photoreceptor progenitors

Also Published As

Publication number Publication date
WO2012012803A2 (en) 2012-01-26
JP7412470B2 (ja) 2024-01-12
JP6184865B2 (ja) 2017-08-23
AU2011280878B2 (en) 2016-06-16
JP2013535194A (ja) 2013-09-12
US20240026419A1 (en) 2024-01-25
EP3875599A1 (en) 2021-09-08
JP6630657B2 (ja) 2020-01-15
EP2596119A2 (en) 2013-05-29
US20130302824A1 (en) 2013-11-14
US11739366B2 (en) 2023-08-29
CA2806127C (en) 2021-12-21
EP2596119B1 (en) 2021-04-28
CA2806127A1 (en) 2012-01-26
EP2596119B8 (en) 2021-06-02
JP2022095696A (ja) 2022-06-28
JP7125382B2 (ja) 2022-08-24
ES2874953T3 (es) 2021-11-05
WO2012012803A3 (en) 2012-11-01
PT2596119T (pt) 2021-06-18
HUE054517T2 (hu) 2021-09-28
JP2017079752A (ja) 2017-05-18
JP2024026528A (ja) 2024-02-28
PL2596119T3 (pl) 2021-12-06
JP2020048573A (ja) 2020-04-02
EP2596119A4 (en) 2013-12-04

Similar Documents

Publication Publication Date Title
DK2596119T3 (da) Fremgangsmåder til påvisning af sjældne subpopulationer af celler og stærkt oprensede sammensætninger af celler
DK3202460T3 (da) Arylmethoxy-isoindolinderivater og sammensætninger omfattende og fremgangsmåder til anvendelser af samme
SMT201600181B (it) Composti antiparassitari di diidroazolo e composizioni che li comprendono
SMT201600085B (it) Piperidin-4-il azetidin derivati come inibitori di jak1
DK2533761T3 (da) Fremgangsmåder og sammensætninger til fremstilling af aerosoler
DK2470656T3 (da) Sammensætning til hæmning af genekspression og anvendelser heraf
DK2459715T3 (da) Fremgangsmåde til at oprense rekombinant adamts13 og andre proteiner og sammensætninger deraf
DK2775928T3 (da) Systemer og fremgangsmåder til forarbejdning af celler
DK3329775T3 (da) Fremgangsmåder til syntese af diarylthiohydantoin- og diarylhydantoinforbindelser
DK2565193T3 (da) Sammensætninger og fremgangsmåder til hæmning af JAK-signalvejen
DK3795573T3 (da) Bestemte triazolopyraziner, sammensætninger deraf og fremgangsmåder til anvendelse deraf
DK3626258T3 (da) Fremgangsmåder og sammensætninger til cns-levering af iduronat-2-sulfatase
DK3176128T3 (da) Fremgangsmåde og system til lagring af hydrogen
DK2593131T3 (da) Fremgangsmåder og sammensætninger til cns-levering af iduronat-2-sulfatase
DK2591233T3 (da) System og fremgangsmåde til håndtering af vindmølletårnsektioner
DK2606003T3 (da) Anordning, system og fremgangsmåde til fremstilling af hydrogen
DK2554160T3 (da) Fremgangsmåde til fremstilling af en beriget IgG-sammensætning fra plasma
DK2625253T3 (da) System og fremgangsmåde til ristning af biomasse
DK3192500T3 (da) Sammensætninger til kontinuerlig indgivelse af dopa-decarboxylasehæmmere
DK2768321T3 (da) Fremgangsmåder og sammensætninger til induktion af mæthed
DK2598483T3 (da) Ampk-aktiverende heterocykliske forbindelser og fremgangsmåder til anvendelse af disse
DK3128014T3 (da) Midler og fremgangsmåder til sterilisering af biofunktionelle sammensætninger
DK2598500T3 (da) Sammensætninger og fremgangsmåder til hæmning af jak-reaktionsvejen
DK3109326T3 (da) Sammensætning og fremgangsmåde til nukleinsyresyntese og amplifikation under anvendelse af rt
DK2552484T3 (da) Fremgangsmåder og sammensætninger til reducering af parathyroidniveauer