DK2571519T3 - Marker vaccine against classical swine fever - Google Patents

Marker vaccine against classical swine fever Download PDF

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Publication number
DK2571519T3
DK2571519T3 DK11724548.0T DK11724548T DK2571519T3 DK 2571519 T3 DK2571519 T3 DK 2571519T3 DK 11724548 T DK11724548 T DK 11724548T DK 2571519 T3 DK2571519 T3 DK 2571519T3
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Prior art keywords
virus
swine fever
substitution
amino acid
strain
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DK11724548.0T
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Danish (da)
English (en)
Inventor
Martin Beer
Sandra Blome
Immanuel Leifer
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Idt Biologika Gmbh
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Publication of DK2571519T3 publication Critical patent/DK2571519T3/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08RNA viruses
    • C07K14/18Togaviridae; Flaviviridae
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/542Mucosal route oral/gastrointestinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6081Albumin; Keyhole limpet haemocyanin [KLH]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24311Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24311Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24334Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Plant Pathology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK11724548.0T 2010-05-18 2011-05-18 Marker vaccine against classical swine fever DK2571519T3 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
EP10075207 2010-05-18
EP10075205 2010-05-18
EP10075206 2010-05-18
DE102010017006 2010-05-18
EP10075760 2010-12-17
EP10075759 2010-12-17
EP11159207 2011-03-22
PCT/EP2011/002624 WO2011144360A1 (en) 2010-05-18 2011-05-18 Marker vaccine for classical swine fever

Publications (1)

Publication Number Publication Date
DK2571519T3 true DK2571519T3 (en) 2016-10-17

Family

ID=44461927

Family Applications (1)

Application Number Title Priority Date Filing Date
DK11724548.0T DK2571519T3 (en) 2010-05-18 2011-05-18 Marker vaccine against classical swine fever

Country Status (19)

Country Link
US (1) US9315873B2 (pt)
EP (1) EP2571519B1 (pt)
KR (1) KR101845571B1 (pt)
CN (1) CN102905725B (pt)
BR (1) BR112012029145B8 (pt)
CA (1) CA2801897C (pt)
CY (1) CY1118060T1 (pt)
DK (1) DK2571519T3 (pt)
EA (1) EA031518B1 (pt)
ES (1) ES2593965T3 (pt)
HR (1) HRP20161225T1 (pt)
HU (1) HUE029385T2 (pt)
MX (1) MX337048B (pt)
PL (1) PL2571519T3 (pt)
PT (1) PT2571519T (pt)
RS (1) RS55214B1 (pt)
SI (1) SI2571519T1 (pt)
WO (1) WO2011144360A1 (pt)
ZA (1) ZA201208194B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103159858B (zh) * 2013-02-26 2014-06-04 中国农业科学院上海兽医研究所 猪瘟分支肽及其应用
WO2015177369A1 (en) * 2014-05-23 2015-11-26 Boehringer Ingelheim Vetmedica Gmbh Recombinant classical swine fever virus (csfv) comprising substitution in the tav epitope of the e2 protein

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1985705A3 (en) * 1994-06-17 2008-12-10 Instituut voor Dierhouderij en Diergezondheid Nucleotide sequences of pestivirus strains, polypeptides encoded by these sequences and use thereof for diagnosis and prevention of pestivirus infections
US8846055B2 (en) * 2006-05-30 2014-09-30 The United States Of America, As Represented By The Secretary Of Agriculture Virulence determinant within the E2 structural glycoprotein of classical swine fever virus
US8133495B2 (en) * 2007-05-22 2012-03-13 The United States Of America As Represented By The Secretary Of Agriculture Live attenuated antigenically marked classical swine fever virus
EP2202298A1 (en) 2008-12-23 2010-06-30 Stichting Dienst Landbouwkundig Onderzoek Recombinant classical swine fever virus (CSFV) comprising a modified E2 protein and methods for generating said recombinant CSFV

Also Published As

Publication number Publication date
US20130129762A1 (en) 2013-05-23
SI2571519T1 (sl) 2017-01-31
ZA201208194B (en) 2014-01-29
US9315873B2 (en) 2016-04-19
HUE029385T2 (en) 2017-02-28
EP2571519B1 (en) 2016-06-29
RS55214B1 (sr) 2017-02-28
EA201270794A8 (ru) 2017-10-31
BR112012029145A2 (pt) 2020-07-07
BR112012029145B1 (pt) 2021-09-14
CY1118060T1 (el) 2017-06-28
CA2801897C (en) 2019-01-15
KR101845571B1 (ko) 2018-04-04
PL2571519T3 (pl) 2017-07-31
MX337048B (es) 2016-02-11
MX2012013419A (es) 2013-01-28
BR112012029145B8 (pt) 2022-03-08
EA201270794A1 (ru) 2013-04-30
CN102905725A (zh) 2013-01-30
KR20130109008A (ko) 2013-10-07
PT2571519T (pt) 2016-10-03
HRP20161225T1 (hr) 2016-12-02
WO2011144360A1 (en) 2011-11-24
ES2593965T3 (es) 2016-12-14
EP2571519A1 (en) 2013-03-27
EA031518B1 (ru) 2019-01-31
CN102905725B (zh) 2016-01-20
CA2801897A1 (en) 2011-11-24

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