DK2515855T6 - Kombinationsterapi til COPD - Google Patents

Kombinationsterapi til COPD Download PDF

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Publication number
DK2515855T6
DK2515855T6 DK10799030.1T DK10799030T DK2515855T6 DK 2515855 T6 DK2515855 T6 DK 2515855T6 DK 10799030 T DK10799030 T DK 10799030T DK 2515855 T6 DK2515855 T6 DK 2515855T6
Authority
DK
Denmark
Prior art keywords
copd
combination therapy
therapy
combination
Prior art date
Application number
DK10799030.1T
Other languages
English (en)
Other versions
DK2515855T3 (da
Inventor
Sauro Bonelli
Francesca Usberti
Enrico Zambelli
Original Assignee
Chiesi Farm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42107420&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2515855(T6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiesi Farm Spa filed Critical Chiesi Farm Spa
Application granted granted Critical
Publication of DK2515855T3 publication Critical patent/DK2515855T3/da
Publication of DK2515855T6 publication Critical patent/DK2515855T6/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/124—Aerosols; Foams characterised by the propellant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/04—Methods of, or means for, filling the material into the containers or receptacles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B31/00—Packaging articles or materials under special atmospheric or gaseous conditions; Adding propellants to aerosol containers
    • B65B31/003—Adding propellants in fluid form to aerosol containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B7/00—Closing containers or receptacles after filling
    • B65B7/16—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons
    • B65B7/28—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by applying separate preformed closures, e.g. lids, covers
    • B65B7/2842—Securing closures on containers
    • B65B7/285—Securing closures on containers by deformation of the closure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • External Artificial Organs (AREA)
DK10799030.1T 2009-12-23 2010-12-22 Kombinationsterapi til COPD DK2515855T6 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09180671 2009-12-23
PCT/EP2010/070479 WO2011076843A2 (en) 2009-12-23 2010-12-22 Combination therapy for copd

Publications (2)

Publication Number Publication Date
DK2515855T3 DK2515855T3 (da) 2014-06-30
DK2515855T6 true DK2515855T6 (da) 2023-06-06

Family

ID=42107420

Family Applications (1)

Application Number Title Priority Date Filing Date
DK10799030.1T DK2515855T6 (da) 2009-12-23 2010-12-22 Kombinationsterapi til COPD

Country Status (39)

Country Link
US (3) US20110150782A1 (da)
EP (1) EP2515855B3 (da)
JP (2) JP5914354B2 (da)
KR (2) KR20170040392A (da)
CN (2) CN102665679B (da)
AR (2) AR079726A1 (da)
AU (3) AU2010334859A1 (da)
BR (1) BR112012015337B8 (da)
CA (1) CA2785321C (da)
CL (1) CL2012001705A1 (da)
CO (1) CO6541628A2 (da)
CY (2) CY1115116T1 (da)
DK (1) DK2515855T6 (da)
EA (2) EA027778B1 (da)
ES (1) ES2468840T7 (da)
FI (1) FI2515855T6 (da)
GE (1) GEP20156311B (da)
HK (2) HK1174566A1 (da)
HR (1) HRP20140582T4 (da)
HU (1) HUS1800001I1 (da)
IL (1) IL260932B (da)
LT (1) LTC2515855I2 (da)
LU (1) LUC00060I2 (da)
MA (1) MA33823B1 (da)
MX (1) MX2012006878A (da)
MY (1) MY156949A (da)
NL (1) NL300923I2 (da)
NZ (1) NZ600790A (da)
PE (2) PE20160853A1 (da)
PL (1) PL2515855T6 (da)
PT (1) PT2515855E (da)
RS (1) RS53391B2 (da)
SG (1) SG181868A1 (da)
SI (1) SI2515855T1 (da)
TN (1) TN2012000269A1 (da)
TW (1) TWI495468B (da)
UA (1) UA113832C2 (da)
WO (1) WO2011076843A2 (da)
ZA (1) ZA201204615B (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2515855B3 (en) * 2009-12-23 2023-05-03 Chiesi Farmaceutici S.p.A. Combination therapy for COPD
SG181870A1 (en) * 2009-12-23 2012-07-30 Chiesi Farma Spa Aerosol formulation for copd
BR112012015334A2 (pt) * 2009-12-23 2016-03-15 Chiesi Farma Spa terapia combinada para doença pulmonar obstrutiva crônica
CA2827045A1 (en) * 2011-02-17 2012-08-23 Cipla Limited Compositions of glycopyrrolate and a beta2-agonist
SI2765994T1 (sl) * 2011-10-11 2019-02-28 Chiesi Farmaceutici S.P.A. Kristalni mikrodelci beta-agonista, obloženi z maščobno kislino
CA2885767A1 (en) * 2012-10-23 2014-05-01 Cipla Limited Pharmaceutical composition
SI3019153T1 (sl) 2013-07-11 2018-12-31 Chiesi Farmaceutici S.P.A. Formulacija suhega praška, obsegajoča antiholinergik, kortikosteroid in beta-adrenergik, za dajanje z inhalacijo
EP3384898A1 (en) 2013-12-30 2018-10-10 Chiesi Farmaceutici S.p.A. Stable pressurised aerosol solution composition of glycopyrronium bromide and formoterol combination
PL3096737T3 (pl) * 2013-12-30 2018-08-31 Chiesi Farmaceutici S.P.A. Stabilna kompozycja w postaci ciśnieniowego roztworu aerozolowego kombinacji bromku glikopironium i formoterolu
US11039620B2 (en) 2014-02-19 2021-06-22 Corning Incorporated Antimicrobial glass compositions, glasses and polymeric articles incorporating the same
US9622483B2 (en) 2014-02-19 2017-04-18 Corning Incorporated Antimicrobial glass compositions, glasses and polymeric articles incorporating the same
US11039621B2 (en) 2014-02-19 2021-06-22 Corning Incorporated Antimicrobial glass compositions, glasses and polymeric articles incorporating the same
US9554992B2 (en) * 2014-06-09 2017-01-31 Chiesi Farmaceutici S.P.A. Inhalation particles comprising a combination of an anticholinergic, a corticosteroid and a beta-adrenergic
GB201416909D0 (en) * 2014-09-25 2014-11-12 Prosonix Ltd Method of forming concentrated solution
US20160310410A1 (en) 2015-04-24 2016-10-27 Glenmark Specialty S.A. Pharmaceutical compositions comprising arformoterol and glycopyrronium
HUE049751T2 (hu) * 2015-11-16 2020-10-28 Chiesi Farm Spa Eljárás antikolinerg szert, kortikoszteroidot és béta-adrenerg szert tartalmazó száraz porkészítmény elõállítására
GB2545025A (en) * 2015-12-04 2017-06-07 Mexichem Fluor Sa De Cv Pharmaceutical composition
WO2017167737A1 (en) 2016-03-31 2017-10-05 Chiesi Farmaceutici S.P.A. Aerosol inhalation device
US10098837B2 (en) * 2016-07-28 2018-10-16 Chiesi Farmaceutici S.P.A. Combination therapy for COPD
EP3515432B1 (en) * 2016-09-19 2021-08-25 Mexichem Fluor S.A. de C.V. Pharmaceutical composition comprising glycopyrrolate
BR112019005168A2 (pt) 2016-09-19 2019-06-11 Mexichem Fluor Sa De Cv composição farmacêutica, recipiente vedado, inalador de dose medida, e, métodos para tratar um paciente que sofre ou susceptível de sofrer de um distúrbio respiratório, para melhoria da estabilidade de uma composição farmacêutica e do desempenho de aerossolização de uma composição farmacêutica e para reduzir o potencial de aquecimento global de uma composição farmacêutica
ES2904823T3 (es) * 2016-09-19 2022-04-06 Mexichem Fluor Sa De Cv Composición farmacéutica que comprende bromuro de tiotropio
RU2742376C1 (ru) * 2017-05-11 2021-02-05 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Способ получения состава сухого порошка, содержащего антихолинергическое средство, кортикостероид и бета-адренергетик
WO2018206619A1 (en) * 2017-05-11 2018-11-15 Chiesi Farmaceutici S.P.A. A process for preparing a dry powder formulation comprising an anticholinergic, a corticosteroid and a beta-adrenergic
IL293328A (en) 2019-12-02 2022-07-01 Chiesi Farm Spa Stainless steel canister for pressurized metered dose inhalers
BR112023001689A2 (pt) 2020-07-31 2023-05-02 Chemo Res S L Terapia de combinação para administração por inalação
CA3193038A1 (en) 2020-10-09 2022-04-14 Enrico Zambelli A pharmaceutical formulation for pressurised metered dose inhaler
WO2023227782A1 (en) 2022-05-27 2023-11-30 Chiesi Farmaceutici S.P.A. A pharmaceutical formulation for pressurised metered dose inhaler
WO2023227781A1 (en) 2022-05-27 2023-11-30 Chiesi Farmaceutici S.P.A. A pharmaceutical formulation for pressurised metered dose inhaler
WO2023227783A1 (en) 2022-05-27 2023-11-30 Chiesi Farmaceutici S.P.A. A pharmaceutical formulation for pressurised metered dose inhaler

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2956062A (en) 1959-02-26 1960-10-11 Robins Co Inc A H Esters of amino alcohols
KR100312357B1 (ko) 1992-12-09 2002-04-24 데이비드 이. 프랭크하우저 안정화된약제의에어로졸용액제제
EP1100465B1 (de) 1998-07-24 2004-11-24 Jago Research Ag Medizinische aerosolformulierungen
US6475467B1 (en) * 1998-08-04 2002-11-05 Jago Research Ag Medicinal aerosol formulations
US20060171899A1 (en) * 1998-12-10 2006-08-03 Akwete Adjei Water-stabilized aerosol formulation system and method of making
IT1317720B1 (it) 2000-01-07 2003-07-15 Chiesi Farma Spa Dispositivo per la somministrazione di aerosol dosati pressurizzati inpropellenti idrofluoroalcani.
GB0008660D0 (en) 2000-04-07 2000-05-31 Arakis Ltd The treatment of respiratory diseases
US20060257324A1 (en) * 2000-05-22 2006-11-16 Chiesi Farmaceutici S.P.A. Pharmaceutical solution formulations for pressurised metered dose inhalers
ME00220B (me) * 2000-05-22 2010-10-10 Chiesi Farm Spa Stabilne farmaceutske formulacije rastvora za inhalatore odmjerene doze pod pritiskom
NZ528640A (en) 2001-03-30 2004-06-25 Jagotec Ag Medical aerosol formulations
US6667344B2 (en) 2001-04-17 2003-12-23 Dey, L.P. Bronchodilating compositions and methods
EP1321159A1 (en) 2001-12-21 2003-06-25 CHIESI FARMACEUTICI S.p.A. Pressurized metered dose inhaler (pMDI) actuators with laser drilled orifices
ME00077B (me) 2002-03-01 2010-06-10 Chiesi Farm Spa Formoterol najfiniji preparat
CA2510043A1 (en) 2002-12-16 2004-07-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Tiotropium containing hfc solution formulations
AR041873A1 (es) * 2003-10-30 2005-06-01 Pablo Cassara Srl Lab Una formulacion farmaceutica en aerosol adecuada para la inhalacion oral o nasal que contienen glucocorticoides en solucion estable al almacenamiento; un metodo para estabilzar formulaciones y uso de un agente estabilizante
WO2005074900A2 (en) * 2004-02-06 2005-08-18 Meda Pharma Gmbh & Co. Kg NOVEL COMBINATION OF ANTICHOLINERGIC AND β MIMETICS FOR THE TREATMENT OF RESPIRATORY DISEASES
WO2005074918A1 (en) 2004-02-06 2005-08-18 Benzstrasse 1 D-61352 Bad Homburd The combination of anticholinergics and glucocorticoids for the long-term treatment of asthma and copd
GB0410399D0 (en) 2004-05-10 2004-06-16 Arakis Ltd The treatment of respiratory disease
GB0411056D0 (en) 2004-05-18 2004-06-23 Novartis Ag Organic compounds
EP1616567A1 (en) 2004-07-16 2006-01-18 Boehringer Ingelheim Pharma GmbH & Co.KG Medicaments for inhalation comprising PDE IV inhibitors and glycopyrrolate salts
GB0505545D0 (en) 2005-03-17 2005-04-27 Glaxo Group Ltd Inhalation devices
WO2006105401A2 (en) 2005-03-30 2006-10-05 Schering Corporation Medicaments and methods combining an anticholinergic, a corticosteroid, and a long acting beta agonist
GB0523653D0 (en) 2005-11-21 2005-12-28 Novartis Ag Organic compounds
AU2006276343B2 (en) 2005-08-01 2009-10-08 Astrazeneca Ab Inhaler valve
GB0523656D0 (en) 2005-11-21 2005-12-28 Novartis Ag Organic compounds
GB0523655D0 (en) 2005-11-21 2005-12-28 Novartis Ag Organic compounds
GB0523654D0 (en) 2005-11-21 2005-12-28 Novartis Ag Organic compounds
EP1971369B1 (en) 2005-12-21 2009-08-19 MEDA Pharma GmbH & Co. KG Combination of r,r-glycopyrrolate, rolipram and budesonide for the treatment of inflammatory diseases
GB0613161D0 (en) * 2006-06-30 2006-08-09 Novartis Ag Organic Compounds
EP1894568A1 (en) 2006-08-31 2008-03-05 Novartis AG Pharmaceutical compositions for the treatment of inflammatory or obstructive airway diseases
CA2702830C (en) 2007-10-18 2017-02-28 Stiefel Research Australia Pty Ltd Topical glycopyrrolate formulations
EP2440196A4 (en) * 2009-06-09 2013-01-02 Elevation Pharmaceuticals Inc TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE BY ADMINISTRATION OF BETA 2 NEBULIZED AGONIST OR A COMBINATION OF BETA 2 NEBULIZED AGONIST AND ANTICHOLINERGIC
EP2515856B1 (en) 2009-12-23 2014-04-02 Chiesi Farmaceutici S.p.A. Aerosol Formulation for COPD
BR112012015334A2 (pt) 2009-12-23 2016-03-15 Chiesi Farma Spa terapia combinada para doença pulmonar obstrutiva crônica
EP2515855B3 (en) * 2009-12-23 2023-05-03 Chiesi Farmaceutici S.p.A. Combination therapy for COPD
SG181870A1 (en) * 2009-12-23 2012-07-30 Chiesi Farma Spa Aerosol formulation for copd
SI3019153T1 (sl) * 2013-07-11 2018-12-31 Chiesi Farmaceutici S.P.A. Formulacija suhega praška, obsegajoča antiholinergik, kortikosteroid in beta-adrenergik, za dajanje z inhalacijo
EP3384898A1 (en) 2013-12-30 2018-10-10 Chiesi Farmaceutici S.p.A. Stable pressurised aerosol solution composition of glycopyrronium bromide and formoterol combination
PL3096737T3 (pl) * 2013-12-30 2018-08-31 Chiesi Farmaceutici S.P.A. Stabilna kompozycja w postaci ciśnieniowego roztworu aerozolowego kombinacji bromku glikopironium i formoterolu
US9554992B2 (en) * 2014-06-09 2017-01-31 Chiesi Farmaceutici S.P.A. Inhalation particles comprising a combination of an anticholinergic, a corticosteroid and a beta-adrenergic
US10098837B2 (en) * 2016-07-28 2018-10-16 Chiesi Farmaceutici S.P.A. Combination therapy for COPD

Also Published As

Publication number Publication date
ES2468840T3 (es) 2014-06-17
HRP20140582T1 (hr) 2014-08-01
HRP20140582T4 (hr) 2023-06-09
SG181868A1 (en) 2012-07-30
LTPA2018001I1 (lt) 2018-02-12
FI2515855T6 (fi) 2023-06-02
US10159645B2 (en) 2018-12-25
US20110150782A1 (en) 2011-06-23
KR20120103653A (ko) 2012-09-19
LUC00060I1 (da) 2018-01-18
ZA201204615B (en) 2013-09-25
CN104055765B (zh) 2016-11-23
CN102665679A (zh) 2012-09-12
TN2012000269A1 (en) 2013-12-12
PT2515855E (pt) 2014-06-11
WO2011076843A3 (en) 2011-12-01
KR20170040392A (ko) 2017-04-12
US11389401B2 (en) 2022-07-19
PE20121396A1 (es) 2012-10-24
RS53391B2 (sr) 2023-09-29
LTC2515855I2 (lt) 2019-05-10
UA113832C2 (xx) 2017-03-27
WO2011076843A2 (en) 2011-06-30
AR115897A2 (es) 2021-03-10
BR112012015337A2 (pt) 2016-03-15
CA2785321C (en) 2018-08-21
JP6283388B2 (ja) 2018-02-21
MA33823B1 (fr) 2012-12-03
SI2515855T1 (sl) 2014-08-29
ES2468840T7 (es) 2023-11-29
PE20160853A1 (es) 2016-09-14
TW201129359A (en) 2011-09-01
IL260932B (en) 2021-04-29
EA201590179A1 (ru) 2015-09-30
AR079726A1 (es) 2012-02-15
PL2515855T3 (pl) 2014-08-29
NL300923I2 (en) 2019-07-22
AU2018202998A1 (en) 2018-05-17
TWI495468B (zh) 2015-08-11
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US20150328144A1 (en) 2015-11-19
EA201290375A1 (ru) 2013-01-30
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JP5914354B2 (ja) 2016-05-11
CL2012001705A1 (es) 2012-09-28
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BR112012015337B8 (pt) 2021-05-25
GEP20156311B (en) 2015-07-10
CY2017047I1 (el) 2018-04-04
EA021917B1 (ru) 2015-09-30
EP2515855B3 (en) 2023-05-03
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CY2017047I2 (el) 2018-04-04
CN104055765A (zh) 2014-09-24
CA2785321A1 (en) 2011-06-30
HK1197036A1 (en) 2015-01-02
HK1174566A1 (en) 2013-06-14
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PL2515855T6 (pl) 2023-12-18
EP2515855A2 (en) 2012-10-31
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JP2013515696A (ja) 2013-05-09
US20190046433A1 (en) 2019-02-14
JP2016145239A (ja) 2016-08-12
MX2012006878A (es) 2012-07-04
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RS53391B (en) 2014-10-31

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