DK2466312T3 - Phosphoethanolamine som biomarkør for depression - Google Patents
Phosphoethanolamine som biomarkør for depression Download PDFInfo
- Publication number
- DK2466312T3 DK2466312T3 DK10808255.3T DK10808255T DK2466312T3 DK 2466312 T3 DK2466312 T3 DK 2466312T3 DK 10808255 T DK10808255 T DK 10808255T DK 2466312 T3 DK2466312 T3 DK 2466312T3
- Authority
- DK
- Denmark
- Prior art keywords
- phosphoethanolamine
- biomarker
- depression
- Prior art date
Links
- SUHOOTKUPISOBE-UHFFFAOYSA-N O-phosphoethanolamine Chemical compound NCCOP(O)(O)=O SUHOOTKUPISOBE-UHFFFAOYSA-N 0.000 title 1
- 239000000090 biomarker Substances 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/30—Psychoses; Psychiatry
- G01N2800/304—Mood disorders, e.g. bipolar, depression
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/16—Phosphorus containing
- Y10T436/163333—Organic [e.g., chemical warfare agents, insecticides, etc.]
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009187521 | 2009-08-12 | ||
| JP2009291029 | 2009-12-22 | ||
| PCT/JP2010/063713 WO2011019072A1 (ja) | 2009-08-12 | 2010-08-12 | うつ病のバイオマーカー、うつ病のバイオマーカーの測定法、コンピュータプログラム、及び記憶媒体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2466312T3 true DK2466312T3 (da) | 2020-01-13 |
Family
ID=43586246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK10808255.3T DK2466312T3 (da) | 2009-08-12 | 2010-08-12 | Phosphoethanolamine som biomarkør for depression |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8951739B2 (enExample) |
| EP (1) | EP2466312B1 (enExample) |
| JP (3) | JPWO2011019072A1 (enExample) |
| CN (2) | CN104777314B (enExample) |
| DK (1) | DK2466312T3 (enExample) |
| WO (1) | WO2011019072A1 (enExample) |
Families Citing this family (46)
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|---|---|---|---|---|
| JP5731860B2 (ja) * | 2011-03-11 | 2015-06-10 | テルモ株式会社 | 腹膜組織の傷害検出方法 |
| EP2778233B1 (en) * | 2011-11-10 | 2017-01-11 | Human Metabolome Technologies, Inc. | Method for measuring ethanolamine phosphate |
| EP3228313B1 (en) | 2013-01-22 | 2019-09-11 | Vistagen Therapeutics, Inc. | Dosage forms and therapeutic uses of l-4-chlorokynurenine |
| JP6211283B2 (ja) * | 2013-03-29 | 2017-10-11 | ヒューマン・メタボローム・テクノロジーズ株式会社 | 脳症の検出方法 |
| CN103630678A (zh) * | 2013-03-29 | 2014-03-12 | 中国科学院城市环境研究所 | 男性不育的生物标志物及其应用 |
| EP2799878A1 (en) * | 2013-05-03 | 2014-11-05 | SALION GmbH | In vitro method for the early detection of a potential inflammation, in particular associated with rejection of a transplant using kynurenine as a marker. |
| HK1223174A1 (zh) * | 2013-05-23 | 2017-07-21 | Iphenotype Llc | 表型整合社交搜索数据库及方法 |
| US20150056605A1 (en) * | 2013-08-21 | 2015-02-26 | Purdue Research Foundation | Identification of blood based metabolite biomarkers of pancreatic cancer |
| CN103529159B (zh) * | 2013-10-18 | 2015-05-13 | 哈尔滨医科大学 | 一种血液非靶标代谢组学研究样品的前处理方法 |
| WO2016047677A1 (ja) * | 2014-09-26 | 2016-03-31 | ヒューマン・メタボローム・テクノロジーズ株式会社 | うつ病治療薬の選択肢を予測する方法 |
| KR101604074B1 (ko) * | 2015-05-14 | 2016-03-17 | 한국과학기술원 | 대사체 프로파일링을 이용한 정신질환의 진단 또는 진행성 예측 방법 및 바이오마커 |
| CN105177117A (zh) * | 2015-07-03 | 2015-12-23 | 张理义 | 重症抑郁障碍生物标记物、筛选方法及试剂盒 |
| CN104991010B (zh) * | 2015-07-29 | 2017-10-13 | 中国药科大学 | 一种区分乳腺癌亚型生物标志物的组合物 |
| EP3677914A1 (en) * | 2015-11-12 | 2020-07-08 | Kyushu University National University Corporation | Biomarker for diagnosing depression and use of biomarker |
| CN105445408B (zh) * | 2016-01-25 | 2018-06-12 | 齐炼文 | 诊断区分冠状动脉粥样硬化和稳定型心绞痛的代谢标志物 |
| CN105486778B (zh) * | 2016-01-25 | 2017-11-03 | 齐炼文 | 诊断区分稳定型心绞痛和急性冠脉综合征的代谢标志物 |
| CA3026049C (en) * | 2016-06-02 | 2024-04-09 | Metabolon, Inc. | Mass spectrometry method for detection and quantitation of metabolites |
| MX2019002918A (es) * | 2016-09-16 | 2019-07-18 | Dyax Corp | Biomarcadores de metabolitos para enfermedades asociadas con el sistema de activacion por contacto. |
| WO2018117064A1 (ja) * | 2016-12-21 | 2018-06-28 | 国立大学法人徳島大学 | うつ状態を呈する疾患を検査する方法 |
| US11869633B2 (en) * | 2017-12-15 | 2024-01-09 | The Board Of Trustees Of The University Of Illinois | Analytics and machine learning framework for actionable intelligence from clinical and omics data |
| US11815515B2 (en) * | 2018-01-17 | 2023-11-14 | University Of Southampton | Methods to predict risk of and to stratify sarcopenia and NAD deficiency |
| CN112689755A (zh) * | 2018-09-11 | 2021-04-20 | 梅塔博隆股份有限公司 | 用于检测和定量微生物区系相关代谢物的质谱测定法 |
| JPWO2020122231A1 (ja) | 2018-12-13 | 2021-10-21 | キッコーマン株式会社 | エタノールアミンリン酸の定量方法、定量用のオキシドレダクターゼ、定量用組成物、定量用キット及び定量用センサー |
| WO2020185580A1 (en) * | 2019-03-13 | 2020-09-17 | Duke University | Methods and compositions for diagnosing depression |
| CN110286191A (zh) * | 2019-06-27 | 2019-09-27 | 山西大学 | 一种生物样品中代谢标志物检测方法及应用 |
| JP7607036B2 (ja) * | 2019-10-11 | 2024-12-26 | ソシエテ・デ・プロデュイ・ネスレ・エス・アー | 気分障害の改善のためのバイオマーカーとしての２－メチルブチレート |
| GB201916185D0 (en) * | 2019-11-07 | 2019-12-25 | Randox Laboratories Ltd | Biomarker of drug-induced cellular toxicity and depression |
| US20210386704A1 (en) * | 2020-06-15 | 2021-12-16 | Universitätsspital Basel | Mdma response prediction |
| EP4170041A4 (en) | 2020-06-17 | 2024-07-17 | Kikkoman Corporation | METHOD FOR QUANTIFICATION OF ETHANOLAMINE PHOSPHATE, OXIDE REDUCTASE FOR QUANTIFICATION, QUANTIFICATION COMPOSITION, QUANTIFICATION KIT, SENSOR CHIP AND SENSOR |
| CN111693624B (zh) * | 2020-06-22 | 2021-07-09 | 南京市中医院 | 一种与儿童多发性抽动症诊断相关的血浆代谢标志物在制备儿童多发性抽动症诊断试剂盒中的应用 |
| CN112630311B (zh) * | 2020-07-09 | 2023-07-18 | 深圳云合医药科技合伙企业(有限合伙) | 用于检测情感障碍的代谢标记物和试剂盒及使用方法 |
| EP4237848A4 (en) * | 2020-10-30 | 2024-09-25 | The Regents of The University of California | COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF PATIENTS WITH A HISTORY OF EARLY LIFE ADVERSE |
| CN114544826B (zh) * | 2020-11-24 | 2023-12-08 | 重庆医科大学 | 检测血浆中组氨酸的试剂在制备抑郁症检测试剂盒中的用途 |
| CN114624345B (zh) * | 2020-12-10 | 2023-06-06 | 中国科学院大连化学物理研究所 | 一种联合生物标志物及其应用 |
| US11854684B2 (en) * | 2020-12-29 | 2023-12-26 | Kpn Innovations, Llc. | Methods and systems for nourishment refinement using psychiatric markers |
| WO2023041681A1 (en) * | 2021-09-17 | 2023-03-23 | Société des Produits Nestlé S.A. | Method for detecting and/or quantifying mood disorder and/or improvements of the mood disorder status using butyrate as biomarker and improved methods and compositions thereof |
| CN117836631A (zh) * | 2021-09-28 | 2024-04-05 | 雀巢产品有限公司 | 使用葫芦巴碱作为生物标志物检测和/或量化心境障碍和/或心境障碍状态改善的方法及其改进的方法和组合物 |
| US12100484B2 (en) | 2021-11-01 | 2024-09-24 | Matterworks Inc | Methods and compositions for analyte quantification |
| US20230137741A1 (en) | 2021-11-01 | 2023-05-04 | Matterworks Inc | Methods and compositions for analyte quantification |
| JP2023069050A (ja) * | 2021-11-04 | 2023-05-18 | 国立大学法人九州大学 | ひきこもりのバイオマーカー、ひきこもり識別支援方法 |
| CN114176581A (zh) * | 2021-12-06 | 2022-03-15 | 重庆邮电大学 | 基于体液中l-酪氨酸含量的抑郁情绪检测装置 |
| CN116429952B (zh) * | 2023-03-27 | 2024-02-02 | 深圳市第二人民医院(深圳市转化医学研究院) | 一种抑郁症标志物及其在抑郁症诊断中的应用、评估装置 |
| CN116990498B (zh) * | 2023-09-28 | 2024-08-09 | 山东大学齐鲁医院 | 血浆色氨酸代谢物在儿童偏头痛诊断中的应用 |
| CN117590005A (zh) * | 2024-01-15 | 2024-02-23 | 中国疾病预防控制中心环境与健康相关产品安全所 | 空气污染致抑郁的代谢标志物组合及其筛选方法和应用 |
| WO2025163640A1 (en) * | 2024-01-31 | 2025-08-07 | Sheba Impact Ltd. | Ai based clinical decision support system (cdss) for mental health |
| CN118566488A (zh) * | 2024-04-10 | 2024-08-30 | 合肥歆智医疗器械有限公司 | 抑郁症检测用试剂组合、制造方法、检测系统及其应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ314144A (en) * | 1996-02-02 | 1999-04-29 | Smithkline Beecham Corp | Computerised identification of at risk patients diagnosed with depression |
| GB9826899D0 (en) * | 1998-12-08 | 1999-01-27 | Knoll Ag | Methods to treat depression and other psychiatric disorders and assays for compounds |
| WO2004080312A1 (ja) | 2003-03-14 | 2004-09-23 | Seizaburo Arita | うつ病の診断方法 |
| EP2146209B1 (en) | 2005-04-06 | 2011-11-16 | University of Antwerp | Neurodegenerative markers for Alzheimer's disease |
| JP2007024822A (ja) | 2005-07-21 | 2007-02-01 | Aska Pharmaceutical Co Ltd | 男性の更年期又はうつ病の鑑別方法 |
| GB0524609D0 (en) * | 2005-12-02 | 2006-01-11 | Univ Cambridge Tech | Methods of monitoring and diagnosing psychotic disorders and of identifying biomarkers for psychotic disorders |
| US7606622B2 (en) * | 2006-01-24 | 2009-10-20 | Cardiac Pacemakers, Inc. | Method and device for detecting and treating depression |
| US20080281531A1 (en) | 2007-03-15 | 2008-11-13 | Kazuhito Rokutan | Method for Diagnosing Depression |
| CN101796408B (zh) * | 2007-06-29 | 2014-05-07 | 奎斯特诊断投资公司 | 用液相层析-质谱法分析体液内的氨基酸 |
| CN101338337B (zh) * | 2007-07-04 | 2011-11-02 | 北京华安佛医药研究中心有限公司 | 多态性位点基因型预测抑郁症及药效的用途、方法和试剂盒 |
| JP2009092550A (ja) | 2007-10-10 | 2009-04-30 | Japan Health Science Foundation | うつ病またはうつ状態の同定方法 |
| JP2009187521A (ja) | 2008-01-08 | 2009-08-20 | Yaskawa Electric Corp | 位置指令作成方法及び位置指令作成装置 |
| JP2009291029A (ja) | 2008-05-30 | 2009-12-10 | Yazaki Corp | コルゲートチューブ配索部材 |
-
2010
- 2010-08-12 WO PCT/JP2010/063713 patent/WO2011019072A1/ja not_active Ceased
- 2010-08-12 CN CN201510161121.9A patent/CN104777314B/zh not_active Expired - Fee Related
- 2010-08-12 CN CN201080046087.6A patent/CN102667485B/zh active Active
- 2010-08-12 EP EP10808255.3A patent/EP2466312B1/en active Active
- 2010-08-12 US US13/389,903 patent/US8951739B2/en active Active
- 2010-08-12 JP JP2011526785A patent/JPWO2011019072A1/ja active Pending
- 2010-08-12 DK DK10808255.3T patent/DK2466312T3/da active
-
2012
- 2012-05-28 JP JP2012121097A patent/JP5372213B2/ja active Active
-
2013
- 2013-09-17 JP JP2013191911A patent/JP5859502B2/ja active Active
-
2014
- 2014-12-29 US US14/584,708 patent/US9442121B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN102667485A (zh) | 2012-09-12 |
| US8951739B2 (en) | 2015-02-10 |
| JP5372213B2 (ja) | 2013-12-18 |
| CN104777314B (zh) | 2017-01-04 |
| US20120282592A1 (en) | 2012-11-08 |
| US9442121B2 (en) | 2016-09-13 |
| JP2014013257A (ja) | 2014-01-23 |
| CN102667485B (zh) | 2015-04-22 |
| CN104777314A (zh) | 2015-07-15 |
| EP2466312B1 (en) | 2019-10-16 |
| EP2466312A4 (en) | 2013-03-13 |
| EP2466312A1 (en) | 2012-06-20 |
| JPWO2011019072A1 (ja) | 2013-01-17 |
| JP2012211908A (ja) | 2012-11-01 |
| JP5859502B2 (ja) | 2016-02-10 |
| US20150126623A1 (en) | 2015-05-07 |
| WO2011019072A1 (ja) | 2011-02-17 |
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