DK2343380T3 - Immunoglobulin variabel region kassetteudskiftning - Google Patents

Immunoglobulin variabel region kassetteudskiftning Download PDF

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Publication number
DK2343380T3
DK2343380T3 DK10014128.2T DK10014128T DK2343380T3 DK 2343380 T3 DK2343380 T3 DK 2343380T3 DK 10014128 T DK10014128 T DK 10014128T DK 2343380 T3 DK2343380 T3 DK 2343380T3
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DK
Denmark
Prior art keywords
variable region
immunoglobulin variable
cartridge replacement
region cartridge
replacement
Prior art date
Application number
DK10014128.2T
Other languages
Danish (da)
English (en)
Inventor
Christopher Bebbington
Geoffrey Yarranton
Kenneth Luehrsen
Original Assignee
Humanigen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Humanigen Inc filed Critical Humanigen Inc
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Publication of DK2343380T3 publication Critical patent/DK2343380T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • C07K16/461Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/464Igs containing CDR-residues from one specie grafted between FR-residues from another
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1075General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of amino acids or peptide residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/005Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567Framework region [FR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK10014128.2T 2004-11-16 2005-11-16 Immunoglobulin variabel region kassetteudskiftning DK2343380T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62858104P 2004-11-16 2004-11-16
EP05851809.3A EP1824987B1 (en) 2004-11-16 2005-11-16 Immunoglobulin variable region cassette exchange

Publications (1)

Publication Number Publication Date
DK2343380T3 true DK2343380T3 (da) 2019-09-09

Family

ID=36407771

Family Applications (2)

Application Number Title Priority Date Filing Date
DK10014128.2T DK2343380T3 (da) 2004-11-16 2005-11-16 Immunoglobulin variabel region kassetteudskiftning
DK19169135.1T DK3540062T3 (da) 2004-11-16 2005-11-16 Immunoglobulin-variabel region kassetteudskiftning

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK19169135.1T DK3540062T3 (da) 2004-11-16 2005-11-16 Immunoglobulin-variabel region kassetteudskiftning

Country Status (10)

Country Link
US (2) US20060134098A1 (https=)
EP (3) EP2343380B1 (https=)
JP (1) JP2008520586A (https=)
AU (1) AU2005306502B2 (https=)
CA (1) CA2587158C (https=)
DK (2) DK2343380T3 (https=)
ES (3) ES2881353T3 (https=)
PL (2) PL3540062T3 (https=)
PT (2) PT2343380T (https=)
WO (1) WO2006055778A2 (https=)

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Also Published As

Publication number Publication date
AU2005306502A1 (en) 2006-05-26
PL2343380T3 (pl) 2020-03-31
EP3540062B1 (en) 2021-05-12
DK3540062T3 (da) 2021-06-28
US10919983B2 (en) 2021-02-16
CA2587158A1 (en) 2006-05-26
AU2005306502B2 (en) 2012-11-15
US20160102152A1 (en) 2016-04-14
WO2006055778A3 (en) 2006-11-23
EP1824987A2 (en) 2007-08-29
JP2008520586A (ja) 2008-06-19
EP2343380B1 (en) 2019-06-12
US20060134098A1 (en) 2006-06-22
PT3540062T (pt) 2021-07-06
EP3540062A1 (en) 2019-09-18
ES2744149T3 (es) 2020-02-21
PT2343380T (pt) 2019-09-18
EP2343380A1 (en) 2011-07-13
CA2587158C (en) 2016-01-12
WO2006055778A2 (en) 2006-05-26
EP1824987A4 (en) 2008-03-19
EP1824987B1 (en) 2013-08-21
PL3540062T3 (pl) 2021-12-27
ES2881353T3 (es) 2021-11-29
ES2429541T3 (es) 2013-11-15

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