DK2288439T3 - Apparat og fremgangsmåde til fremstilling af nanopartikler i kontinuerlig strømningstilstand - Google Patents
Apparat og fremgangsmåde til fremstilling af nanopartikler i kontinuerlig strømningstilstand Download PDFInfo
- Publication number
- DK2288439T3 DK2288439T3 DK09738445T DK09738445T DK2288439T3 DK 2288439 T3 DK2288439 T3 DK 2288439T3 DK 09738445 T DK09738445 T DK 09738445T DK 09738445 T DK09738445 T DK 09738445T DK 2288439 T3 DK2288439 T3 DK 2288439T3
- Authority
- DK
- Denmark
- Prior art keywords
- nanoparticles
- procedure
- preparation
- continuous flow
- flow state
- Prior art date
Links
- 239000002105 nanoparticle Substances 0.000 title 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/0004—Preparation of sols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nanotechnology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Gynecology & Obstetrics (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Manufacture Of Metal Powder And Suspensions Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU0800281A HU230862B1 (hu) | 2008-04-28 | 2008-04-28 | Berendezés és eljárás nanorészecskék folyamatos üzemű előállítására |
PCT/HU2009/000040 WO2009133418A1 (en) | 2008-04-28 | 2009-04-28 | Instrument and process for nanoparticles production in continuous flow mode |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2288439T3 true DK2288439T3 (da) | 2019-12-02 |
Family
ID=89988246
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK09738445T DK2288439T3 (da) | 2008-04-28 | 2009-04-28 | Apparat og fremgangsmåde til fremstilling af nanopartikler i kontinuerlig strømningstilstand |
Country Status (11)
Country | Link |
---|---|
US (1) | US8540939B2 (da) |
EP (1) | EP2288439B1 (da) |
JP (1) | JP5755137B2 (da) |
CN (1) | CN102076405B (da) |
AU (1) | AU2009241682B2 (da) |
DK (1) | DK2288439T3 (da) |
HU (2) | HU230862B1 (da) |
IL (1) | IL208984A (da) |
RU (1) | RU2486003C2 (da) |
UA (1) | UA100053C2 (da) |
WO (1) | WO2009133418A1 (da) |
Families Citing this family (38)
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KR101147840B1 (ko) * | 2008-10-27 | 2012-05-21 | 한국기계연구원 | 복수의 가열 영역을 가지는 양자점 제조 장치 및 양자점 제조 방법 |
US8317894B2 (en) * | 2009-04-15 | 2012-11-27 | Korea Institute Of Science And Technology | Method of producing metal nanoparticles continuously and metal nanoparticles produced thereby |
HUP0900384A2 (en) * | 2009-06-19 | 2011-01-28 | Nangenex Nanotechnologiai Zartkoerueen Muekoedoe Reszvenytarsasag | Nanoparticulate olmesartan medoxomil compositions |
AU2010261510A1 (en) * | 2009-06-19 | 2012-02-09 | Nanoform Hungary Ltd. | Nanostructured Sildenafil base, its pharmaceutically acceptable salts and co-crystals, compositions of them, process for the preparation thereof and pharmaceutical compositions containing them |
HUP0900376A2 (en) * | 2009-06-19 | 2011-01-28 | Nangenex Nanotechnologiai Zartkoerueen Muekoedoe Reszvenytarsasag | Nanoparticulate candesartan cilexetil composition |
HUP1000327A2 (en) * | 2010-06-18 | 2012-01-30 | Druggability Technologies Ip Holdco Jersey Ltd | Composition containing nanostructured ezetibime and process for it's preparation |
HUP1000325A2 (en) * | 2010-06-18 | 2012-01-30 | Druggability Technologies Ip Holdco Jersey Ltd | Nanostructured aprepitant compositions and process for their preparation |
PL399505A1 (pl) | 2012-06-13 | 2013-12-23 | Uniwersytet Warszawski | Sposób wytwarzania zasadniczo czystych nanoczastek w ukladzie przeplywowym, nanoczastki otrzymane tym sposobem oraz ich zastosowanie |
CN103920641B (zh) * | 2013-01-12 | 2016-12-28 | 唐山兴铭科技有限公司 | 一种生产纳米颗粒的工业化装置及其工艺 |
GB2515306B (en) * | 2013-06-18 | 2016-05-25 | Nexeon Ltd | Method and apparatus for preparing metal coated particles |
KR20160067143A (ko) * | 2013-10-04 | 2016-06-13 | 킹 압둘라 유니버시티 오브 사이언스 앤드 테크놀로지 | 퀀텀 도트를 제조하기 위한 시스템 및 방법 |
WO2015071841A1 (en) | 2013-11-12 | 2015-05-21 | Druggability Technologies Holdings Limited | Complexes of dabigatran and its derivatives, process for the preparation thereof and pharmaceutical compositions containing them |
HUP1300646A2 (en) | 2013-11-12 | 2015-05-28 | Druggability Technologies Ip Holdco Jersey Ltd | Complexes of fulvestrant and its derivatives, process for the preparation thereof and pharmaceutical compositions containing them |
HUP1400075A2 (hu) | 2014-02-14 | 2015-08-28 | Druggability Technologies Ip Holdco Jersey Ltd | Sirolimus és származékainak komplexei, elõállítása és gyógyszerészeti kompozíciói |
HU231309B1 (hu) * | 2014-02-25 | 2022-11-28 | Darholding Kft. | Nanostrukturált Indomethacint, gyógyszerészetileg elfogadott sóit és kokristályait tartalmazó készítmény és eljárás előállításukra |
CN106068319A (zh) * | 2014-03-10 | 2016-11-02 | 国立大学法人东京大学 | 水分散性非晶质粒子及其制备方法 |
WO2015151952A1 (ja) * | 2014-03-31 | 2015-10-08 | 株式会社 島津製作所 | ナノ粒子の製造方法 |
MX2017002033A (es) | 2014-08-15 | 2017-08-14 | Massachusetts Inst Technology | Sistemas y metodos para sintetizar productos quimicos, incluyendo ingredientes farmaceuticos activos. |
CN104227011B (zh) * | 2014-08-29 | 2017-04-12 | 南京邮电大学 | 一种宏量制备纳米金属材料的装置及其制备方法 |
CN104986726A (zh) * | 2015-02-25 | 2015-10-21 | 王建伟 | 一种工业化大批量稳定制备量子点的方法 |
CN104984692A (zh) * | 2015-02-25 | 2015-10-21 | 王建伟 | 一种工业化大批量稳定制备量子点的串联装置 |
RU2601451C1 (ru) * | 2015-04-23 | 2016-11-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Алтайский государственный университет" | Способ получения коллоидных полупроводниковых квантовых точек селенида цинка |
EP3108875A1 (en) | 2015-06-23 | 2016-12-28 | Galderma Research & Development | Compositions comprising water dispersible nanoparticles of a retinoid compound |
KR102446858B1 (ko) * | 2015-08-07 | 2022-09-23 | 삼성디스플레이 주식회사 | 양자점 제조 방법 |
CN106552296B (zh) * | 2015-09-29 | 2020-08-14 | 上海氪励铵勤科技发展有限公司 | 纳米粒子、其制备方法与结石取出装置及应用 |
US10369538B2 (en) * | 2015-12-31 | 2019-08-06 | Kuantag Nanoteknolojiler Gelistirme Ve Uretim A.S. | Flow system and process for photoluminescent nanoparticle production |
US10815424B2 (en) | 2015-12-31 | 2020-10-27 | Kuantag Nanoteknolojiler Gelistirme Ve Uretim A.S. | One-step process for synthesis of core shell nanocrystals |
RU174967U1 (ru) * | 2016-01-29 | 2017-11-13 | Общество с ограниченной ответственностью "Банк Стволовых Клеток" | Установка для покрытия материала раствором с наночастицами |
WO2017192595A1 (en) | 2016-05-02 | 2017-11-09 | Massachusetts Institute Of Technology | Reconfigurable multi-step chemical synthesis system and related components and methods |
CN105950151A (zh) * | 2016-05-06 | 2016-09-21 | 京东方科技集团股份有限公司 | 一种热注入法合成的量子点及其合成方法、合成系统 |
JP2018094457A (ja) * | 2016-12-08 | 2018-06-21 | 株式会社Ihi | 反応装置 |
CN106735306A (zh) * | 2017-01-22 | 2017-05-31 | 武汉璟泓万方堂医药科技股份有限公司 | 一种连续制备胶体金的反应装置 |
KR102492563B1 (ko) * | 2017-02-03 | 2023-01-27 | 동우 화인켐 주식회사 | 양자점의 연속흐름 제조방법 및 양자점 연속흐름 제조장치 |
KR102558187B1 (ko) | 2017-02-17 | 2023-07-24 | 메사추세츠 인스티튜트 오브 테크놀로지 | 제약 정제를 비롯한 정제의 제작을 위한 시스템 및 방법 |
EP3870352A2 (en) * | 2018-10-26 | 2021-09-01 | University of Connecticut | A continuous processing system and methods for internal and external modifications to nanoparticles |
HUP2200445A1 (hu) * | 2020-04-06 | 2023-01-28 | Innostudio Zrt | Eljárás egymással nem kompatibilis szervetlen és szerves komponenseket tartalmazó inhomogén vizes oldatok homogén oldattá történõ alakítására |
US20220089949A1 (en) * | 2020-09-22 | 2022-03-24 | Zhuhai Roumei Technology Co.,Ltd. | Method for production of quantum rods using flow reactor |
RU2756051C1 (ru) * | 2020-12-17 | 2021-09-24 | Федеральное государственное бюджетное учреждение науки Институт физики твердого тела Российской академии наук (ИФТТ РАН) | Устройство для получения наночастиц из газов и паров жидкостей при сверхнизких температурах |
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NL194638C (nl) | 1986-12-19 | 2002-10-04 | Novartis Ag | Hydrosol die vaste deeltjes van een farmaceutisch actieve stof bevat en farmaceutisch preparaat dat deze hydrosol bevat. |
JPH0644990B2 (ja) * | 1988-10-13 | 1994-06-15 | 香津雄 堤 | 複合微粉体材料の製造方法 |
US5145684A (en) * | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
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EP1452225B1 (en) * | 2003-02-26 | 2008-09-10 | National Institute of Advanced Industrial Science and Technology | Preparation of nanoparticles |
JP4528927B2 (ja) * | 2003-09-04 | 2010-08-25 | 独立行政法人産業技術総合研究所 | 複合微粒子の製造方法および複合微粒子の製造装置、並びに複合微粒子 |
US7384448B2 (en) * | 2004-02-16 | 2008-06-10 | Climax Engineered Materials, Llc | Method and apparatus for producing nano-particles of silver |
JP4348451B2 (ja) * | 2005-07-06 | 2009-10-21 | 独立行政法人産業技術総合研究所 | ナノ粒子製造方法、及びその装置 |
CN101326001A (zh) * | 2005-12-11 | 2008-12-17 | Scf科技公司 | 纳米材料的生产 |
JP4558657B2 (ja) * | 2006-01-31 | 2010-10-06 | 株式会社ワイエムシィ | 微粒子生成装置及びマイクロチャネル基板 |
TW200811051A (en) * | 2006-07-27 | 2008-03-01 | Ube Industries | Periodic table group XI or XII metal chalcogenide nanoparticles and production process thereof |
UA24393U (en) * | 2007-03-14 | 2007-06-25 | Mykola Vasyliovych Kosinov | Device for preparation of colloidal solutions of nanoparticles of metals |
-
2008
- 2008-04-28 HU HU0800281A patent/HU230862B1/hu unknown
-
2009
- 2009-04-28 RU RU2010146796/04A patent/RU2486003C2/ru active
- 2009-04-28 CN CN200980124532.3A patent/CN102076405B/zh not_active Expired - Fee Related
- 2009-04-28 DK DK09738445T patent/DK2288439T3/da active
- 2009-04-28 UA UAA201014240A patent/UA100053C2/ru unknown
- 2009-04-28 AU AU2009241682A patent/AU2009241682B2/en not_active Ceased
- 2009-04-28 HU HUE09738445A patent/HUE047584T2/hu unknown
- 2009-04-28 EP EP09738445.7A patent/EP2288439B1/en active Active
- 2009-04-28 US US12/990,195 patent/US8540939B2/en active Active
- 2009-04-28 JP JP2011506785A patent/JP5755137B2/ja not_active Expired - Fee Related
- 2009-04-28 WO PCT/HU2009/000040 patent/WO2009133418A1/en active Application Filing
-
2010
- 2010-10-28 IL IL208984A patent/IL208984A/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
JP5755137B2 (ja) | 2015-07-29 |
AU2009241682A1 (en) | 2009-11-05 |
HU0800281D0 (en) | 2008-06-30 |
EP2288439A1 (en) | 2011-03-02 |
CN102076405A (zh) | 2011-05-25 |
EP2288439B1 (en) | 2019-08-28 |
JP2011522787A (ja) | 2011-08-04 |
US20110104043A1 (en) | 2011-05-05 |
AU2009241682B2 (en) | 2015-02-12 |
RU2010146796A (ru) | 2012-06-10 |
HUE047584T2 (hu) | 2020-04-28 |
IL208984A0 (en) | 2011-01-31 |
RU2486003C2 (ru) | 2013-06-27 |
CN102076405B (zh) | 2014-12-10 |
HUP0800281A2 (en) | 2010-03-01 |
IL208984A (en) | 2017-04-30 |
UA100053C2 (ru) | 2012-11-12 |
WO2009133418A1 (en) | 2009-11-05 |
HU230862B1 (hu) | 2018-10-29 |
US8540939B2 (en) | 2013-09-24 |
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