DK2269738T3 - Anordning til PCR-amplificering af mål-DNA-sekvenser - Google Patents

Anordning til PCR-amplificering af mål-DNA-sekvenser

Info

Publication number
DK2269738T3
DK2269738T3 DK10177401.6T DK10177401T DK2269738T3 DK 2269738 T3 DK2269738 T3 DK 2269738T3 DK 10177401 T DK10177401 T DK 10177401T DK 2269738 T3 DK2269738 T3 DK 2269738T3
Authority
DK
Denmark
Prior art keywords
pca
plate
dna sequences
pcr amplification
target dna
Prior art date
Application number
DK10177401.6T
Other languages
English (en)
Inventor
Gabriel Festoc
Original Assignee
Pall Genedisc Technologies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pall Genedisc Technologies filed Critical Pall Genedisc Technologies
Application granted granted Critical
Publication of DK2269738T3 publication Critical patent/DK2269738T3/da

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0803Disc shape
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406Moving fluids with specific forces or mechanical means specific forces capillary forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B01L2400/049Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B01L7/525Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones
    • B01L7/5255Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones by moving sample containers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/54Heating or cooling apparatus; Heat insulating devices using spatial temperature gradients

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
DK10177401.6T 2000-07-28 2001-07-20 Anordning til PCR-amplificering af mål-DNA-sekvenser DK2269738T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0010029A FR2812306B1 (fr) 2000-07-28 2000-07-28 Systeme d'amplification en chaine par polymerse de sequences nucleiques cibles
EP01956628A EP1305115B1 (fr) 2000-07-28 2001-07-20 Dispositif pour l'amplification en chaine thermo-dependante de sequences d'acides nucleiques cibles

Publications (1)

Publication Number Publication Date
DK2269738T3 true DK2269738T3 (da) 2013-01-02

Family

ID=8853103

Family Applications (1)

Application Number Title Priority Date Filing Date
DK10177401.6T DK2269738T3 (da) 2000-07-28 2001-07-20 Anordning til PCR-amplificering af mål-DNA-sekvenser

Country Status (14)

Country Link
US (2) US6821771B2 (da)
EP (2) EP1305115B1 (da)
JP (2) JP4979873B2 (da)
CN (1) CN1248781C (da)
AT (1) ATE532583T1 (da)
AU (2) AU2001278554B2 (da)
BR (1) BR0112789A (da)
CA (1) CA2416756C (da)
DK (1) DK2269738T3 (da)
EA (1) EA004719B1 (da)
ES (2) ES2389763T3 (da)
FR (1) FR2812306B1 (da)
WO (1) WO2002009877A1 (da)
ZA (1) ZA200300700B (da)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2844523B1 (fr) * 2002-09-13 2011-01-14 Genesystems Procede et sequences nucleotidiques pour la detection et l'identification de microorganismes dans un melange complexe ou dans de l'eau
FR2844522A1 (fr) * 2002-09-13 2004-03-19 Genesystems Procede et sequences nucleotidiques pour la detection et l'identification de microorganismes dans un melange complexe
JP2005125311A (ja) * 2003-09-30 2005-05-19 Japan Science & Technology Agency 化学反応装置
DE10360220A1 (de) 2003-12-20 2005-07-21 Steag Microparts Gmbh Mikrostrukturierte Anordnung zur blasenfreien Befüllung zumindest eines Systems zur Ableitung von Flüssigkeiten, Vorrichtung mit einer solchen Anordnung und Befüllungsverfahren
US7709249B2 (en) * 2005-04-01 2010-05-04 3M Innovative Properties Company Multiplex fluorescence detection device having fiber bundle coupling multiple optical modules to a common detector
US7507575B2 (en) * 2005-04-01 2009-03-24 3M Innovative Properties Company Multiplex fluorescence detection device having removable optical modules
US20060246493A1 (en) 2005-04-04 2006-11-02 Caliper Life Sciences, Inc. Method and apparatus for use in temperature controlled processing of microfluidic samples
CN102268367A (zh) * 2005-06-23 2011-12-07 拜欧卡蒂斯股份公司 用于自动医疗诊断的盒体、系统和方法
EP1904234B1 (en) * 2005-06-30 2011-10-19 Biocartis SA Cartridge for automated medical diagnostics
US7527763B2 (en) * 2005-07-05 2009-05-05 3M Innovative Properties Company Valve control system for a rotating multiplex fluorescence detection device
US20070009382A1 (en) * 2005-07-05 2007-01-11 William Bedingham Heating element for a rotating multiplex fluorescence detection device
JP4626891B2 (ja) * 2007-01-29 2011-02-09 ヤマハ株式会社 温度制御装置
JP5141039B2 (ja) * 2007-02-22 2013-02-13 東洋紡株式会社 核酸増幅装置及び核酸増幅方法
EP2182049A1 (en) * 2007-05-23 2010-05-05 Trust Medical Co., Ltd. Container for liquid reaction mixture, reaction-promoting device using the same and method therefor
WO2009002920A1 (en) * 2007-06-22 2008-12-31 Advanced Liquid Logic, Inc. Droplet-based nucleic acid amplification in a temperature gradient
ES2628055T3 (es) 2007-07-27 2017-08-01 R Tree Innovations, Llc Sistema de implantación intercorporal
US20160068905A1 (en) 2007-11-26 2016-03-10 Immunid Method for Studying V(D)J Combinatory Diversity
EP2062982A1 (fr) * 2007-11-26 2009-05-27 ImmunID Procédé d'étude de la diversité combinatoire V(D)J
JP2009240296A (ja) * 2007-12-14 2009-10-22 Ngk Insulators Ltd 流体収容カートリッジ及びその利用
US9121055B2 (en) * 2008-04-24 2015-09-01 3M Innovative Properties Company Analysis of nucleic acid amplification curves using wavelet transformation
JP5372418B2 (ja) 2008-06-23 2013-12-18 株式会社日立ハイテクノロジーズ 核酸分析装置,自動分析装置、及び分析方法
EP2143491A1 (en) * 2008-07-10 2010-01-13 Carpegen GmbH Device for analysing a chemical or biological sample
AT507376B1 (de) * 2008-08-29 2013-09-15 Anagnostics Bioanalysis Gmbh Vorrichtung zum temperieren eines rotationssymetrischen behältnisses
WO2012033396A1 (en) * 2008-12-18 2012-03-15 Universiti Sains Malaysia A disposable multiplex polymerase chain reaction (pcr) chip and device
US9399219B2 (en) * 2009-02-13 2016-07-26 Frank Leo Spangler Thermal Array
RU2612789C2 (ru) * 2009-04-04 2017-03-13 Конинклейке Филипс Электроникс Н.В. Способ детектирования и характеризации токсиногенного штамма clostridium difficile
KR101666947B1 (ko) * 2009-05-20 2016-10-17 스미스 인터내셔널 인크. 절삭 요소, 절삭 요소의 제조 방법 및, 절삭 요소를 포함하는 공구
AU2010257118B2 (en) 2009-06-04 2014-08-28 Lockheed Martin Corporation Multiple-sample microfluidic chip for DNA analysis
JP2011062119A (ja) * 2009-09-16 2011-03-31 Seiko Epson Corp 生体試料定量用チップ
DE102009044431A1 (de) * 2009-11-05 2011-06-22 FRIZ Biochem Gesellschaft für Bioanalytik mbH, 82061 Vorrichtung zur Durchführung einer PCR
US8906624B2 (en) * 2010-03-30 2014-12-09 Korea Advanced Institute Of Science And Technology (Kaist) Rotational PCR equipment and PCR method using the same
JP5249988B2 (ja) * 2010-05-07 2013-07-31 株式会社日立ハイテクノロジーズ 核酸増幅装置及びそれを用いた核酸検査装置
US20110312676A1 (en) * 2010-06-17 2011-12-22 Geneasys Pty Ltd Loc device with integral driver for excitation of electrochemiluminescent luminophores
CA2814720C (en) 2010-10-15 2016-12-13 Lockheed Martin Corporation Micro fluidic optic design
EP2450690A1 (en) * 2010-11-04 2012-05-09 Qiagen GmbH Vessel for Accurate Optical Measurements
US9322054B2 (en) 2012-02-22 2016-04-26 Lockheed Martin Corporation Microfluidic cartridge
US9303281B2 (en) 2012-07-23 2016-04-05 Pall Corporation Compositions for detecting foodstuff spoilage microorganisms
US9382591B2 (en) 2013-06-06 2016-07-05 Pall Corporation Compositions for detecting Alicyclobacillus microorganisms
EP2843057B1 (en) 2013-09-03 2017-12-27 Pall Genedisc Technologies Method for determining the presence or absence of shiga toxin-producing Escherichia coli (STEC) in a food sample
KR101618113B1 (ko) 2014-02-10 2016-05-09 나노바이오시스 주식회사 일 방향 슬라이딩 구동 수단을 구비하는 pcr 장치 및 이를 이용하는 pcr 방법
US10195610B2 (en) 2014-03-10 2019-02-05 Click Diagnostics, Inc. Cartridge-based thermocycler
JP2016049064A (ja) * 2014-09-01 2016-04-11 国立研究開発法人産業技術総合研究所 マイクロチップを用いたpcr装置
CA2972587A1 (en) 2014-12-31 2016-07-07 Click Diagnostics, Inc. Devices and methods for molecular diagnostic testing
US9828626B2 (en) * 2015-07-10 2017-11-28 Pall Corporation Dendrimer conjugates for determining membrane retention level and/or pore structure
CN109642198A (zh) * 2016-02-10 2019-04-16 卡尤迪生物科技(北京)有限公司 用于分析核酸的方法和系统
US10987674B2 (en) 2016-04-22 2021-04-27 Visby Medical, Inc. Printed circuit board heater for an amplification module
WO2017197040A1 (en) 2016-05-11 2017-11-16 Click Diagnostics, Inc. Devices and methods for nucleic acid extraction
WO2018005710A1 (en) 2016-06-29 2018-01-04 Click Diagnostics, Inc. Devices and methods for the detection of molecules using a flow cell
USD800331S1 (en) 2016-06-29 2017-10-17 Click Diagnostics, Inc. Molecular diagnostic device
USD800914S1 (en) 2016-06-30 2017-10-24 Click Diagnostics, Inc. Status indicator for molecular diagnostic device
USD800913S1 (en) 2016-06-30 2017-10-24 Click Diagnostics, Inc. Detection window for molecular diagnostic device
RU2018134774A (ru) * 2016-12-28 2021-01-29 КАБУСИКИ КАЙСЯ Мираи Дженомикс Устройство для анализа
EP3707276A4 (en) 2017-11-09 2022-02-23 Visby Medical, Inc. PORTABLE MOLECULAR DIAGNOSTIC DEVICE AND METHODS FOR DETECTING TARGET VIRUSES
KR102206856B1 (ko) * 2017-12-11 2021-01-25 (주)바이오니아 중합효소 연쇄반응 시스템
KR102065650B1 (ko) * 2017-12-28 2020-02-11 에스디 바이오센서 주식회사 카트리지를 이용한 핵산 추출 방법
KR102076220B1 (ko) 2017-12-28 2020-02-11 에스디 바이오센서 주식회사 핵산 추출용 카트리지의 유로 구조
KR102009505B1 (ko) * 2019-01-17 2019-08-12 주식회사 엘지화학 유전자 증폭 모듈
US11254979B2 (en) * 2020-06-01 2022-02-22 Shaheen Innovations Holding Limited Systems and devices for infectious disease screening
US11730193B2 (en) 2019-12-15 2023-08-22 Shaheen Innovations Holding Limited Hookah device
WO2021138544A1 (en) 2020-01-03 2021-07-08 Visby Medical, Inc. Devices and methods for antibiotic susceptibility testing
CN111607484A (zh) * 2020-05-22 2020-09-01 东莞市东阳光诊断产品有限公司 一种核酸扩增装置及方法
CA3180787A1 (en) 2020-06-01 2021-12-09 Imad Lahoud An infectious disease screening device
GB2612211A (en) 2020-06-01 2023-04-26 Shaheen Innovations Holding Ltd An infectious disease screening system
CN113583854B (zh) * 2021-07-30 2024-02-27 广州和实生物技术有限公司 一种可家庭自测的核酸检测装置、检测方法及用途

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1572596A (en) * 1976-12-06 1980-07-30 Opto Electronic Displays Ltd Apparatus and method for innoculation
DE8813773U1 (da) * 1988-11-03 1989-01-05 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften Ev, 3400 Goettingen, De
FR2672231A1 (fr) * 1991-02-01 1992-08-07 Eibet Appareil d'execution automatique repetee d'un cycle thermique, notamment pour l'amplification du nombre d'une sequence definie d'acide nucleique.
DE4234086A1 (de) * 1992-02-05 1993-08-12 Diagen Inst Molekularbio Verfahren zur bestimmung von in vitro amplifizierten nukleinsaeuresequenzen
US5525300A (en) * 1993-10-20 1996-06-11 Stratagene Thermal cycler including a temperature gradient block
US5639428A (en) * 1994-07-19 1997-06-17 Becton Dickinson And Company Method and apparatus for fully automated nucleic acid amplification, nucleic acid assay and immunoassay
US5556771A (en) * 1995-02-10 1996-09-17 Gen-Probe Incorporated Stabilized compositions of reverse transcriptase and RNA polymerase for nucleic acid amplification
US5609828A (en) * 1995-05-31 1997-03-11 bio M erieux Vitek, Inc. Sample card
CA2250212C (en) * 1996-04-03 2010-02-09 The Perkin-Elmer Corporation Device and method for multiple analyte detection
US5802856A (en) * 1996-07-31 1998-09-08 Stanford University Multizone bake/chill thermal cycling module
AUPO652997A0 (en) * 1997-04-30 1997-05-29 Kindconi Pty Limited Temperature cycling device and method
WO1998053311A2 (en) * 1997-05-23 1998-11-26 Gamera Bioscience Corporation Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system
IL138286A (en) * 1998-03-11 2004-02-19 Steag Micro Parts Gmbh Sample support
DE19810499A1 (de) * 1998-03-11 1999-09-16 Microparts Gmbh Mikrotiterplatte
DE19852835A1 (de) * 1998-11-17 2000-05-18 Stratec Biomedical Systems Ag Probenträger
CA2255850C (en) * 1998-12-07 2000-10-17 Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food Rotary thermocycling apparatus
US6303343B1 (en) * 1999-04-06 2001-10-16 Caliper Technologies Corp. Inefficient fast PCR
DE60038883D1 (de) * 1999-06-22 2008-06-26 Tecan Trading Ag Vorrichtungen zur durchfuehrung von miniaturisierten in vitro amplifizierungsassays
US6706519B1 (en) * 1999-06-22 2004-03-16 Tecan Trading Ag Devices and methods for the performance of miniaturized in vitro amplification assays
US6272939B1 (en) * 1999-10-15 2001-08-14 Applera Corporation System and method for filling a substrate with a liquid sample
US6720148B1 (en) * 2001-02-22 2004-04-13 Caliper Life Sciences, Inc. Methods and systems for identifying nucleotides by primer extension

Also Published As

Publication number Publication date
EP1305115B1 (fr) 2011-11-09
CA2416756C (fr) 2010-01-19
BR0112789A (pt) 2003-09-09
FR2812306B1 (fr) 2005-01-14
WO2002009877A1 (fr) 2002-02-07
ATE532583T1 (de) 2011-11-15
JP5202686B2 (ja) 2013-06-05
CN1458866A (zh) 2003-11-26
CA2416756A1 (fr) 2002-02-07
JP4979873B2 (ja) 2012-07-18
US20020081669A1 (en) 2002-06-27
EA004719B1 (ru) 2004-08-26
FR2812306A1 (fr) 2002-02-01
EP2269738B1 (fr) 2012-08-29
US7732136B2 (en) 2010-06-08
AU2001278554B2 (en) 2006-09-28
JP2004504828A (ja) 2004-02-19
ES2372027T3 (es) 2012-01-13
US6821771B2 (en) 2004-11-23
ES2389763T3 (es) 2012-10-31
US20050026277A1 (en) 2005-02-03
EP1305115A1 (fr) 2003-05-02
ZA200300700B (en) 2004-03-10
EP2269738A1 (fr) 2011-01-05
AU7855401A (en) 2002-02-13
EA200300203A1 (ru) 2003-06-26
CN1248781C (zh) 2006-04-05
JP2011200245A (ja) 2011-10-13

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