DK2205716T3 - MICRO REACTOR - Google Patents

MICRO REACTOR Download PDF

Info

Publication number
DK2205716T3
DK2205716T3 DK08837177.8T DK08837177T DK2205716T3 DK 2205716 T3 DK2205716 T3 DK 2205716T3 DK 08837177 T DK08837177 T DK 08837177T DK 2205716 T3 DK2205716 T3 DK 2205716T3
Authority
DK
Denmark
Prior art keywords
cavity
microreactor
lid
microreactor according
cross
Prior art date
Application number
DK08837177.8T
Other languages
Danish (da)
English (en)
Inventor
Frank Kensy
Jochen Büchs
CARSTEN MüLLER
Matthias Funke
Original Assignee
M2P-Labs Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by M2P-Labs Gmbh filed Critical M2P-Labs Gmbh
Application granted granted Critical
Publication of DK2205716T3 publication Critical patent/DK2205716T3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/38Caps; Covers; Plugs; Pouring means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20Mixing the contents of independent containers, e.g. test tubes
    • B01F31/22Mixing the contents of independent containers, e.g. test tubes with supporting means moving in a horizontal plane, e.g. describing an orbital path for moving the containers about an axis which intersects the receptacle axis at an angle
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/50Mixing receptacles
    • B01F35/53Mixing receptacles characterised by the configuration of the interior, e.g. baffles for facilitating the mixing of components
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/12Well or multiwell plates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/24Gas permeable parts
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00279Features relating to reactor vessels
    • B01J2219/00306Reactor vessels in a multiple arrangement
    • B01J2219/00313Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00315Microtiter plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00479Means for mixing reactants or products in the reaction vessels
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0829Multi-well plates; Microtitration plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0848Specific forms of parts of containers
    • B01L2300/0858Side walls

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Micromachines (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
DK08837177.8T 2007-10-08 2008-10-08 MICRO REACTOR DK2205716T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102007048201 2007-10-08
DE102008008256A DE102008008256A1 (de) 2007-10-08 2008-02-08 Mikroreaktor
PCT/DE2008/001623 WO2009046697A2 (de) 2007-10-08 2008-10-08 Mikroreaktor

Publications (1)

Publication Number Publication Date
DK2205716T3 true DK2205716T3 (en) 2017-12-04

Family

ID=40418270

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08837177.8T DK2205716T3 (en) 2007-10-08 2008-10-08 MICRO REACTOR

Country Status (7)

Country Link
US (1) US8828337B2 (cg-RX-API-DMAC7.html)
EP (1) EP2205716B1 (cg-RX-API-DMAC7.html)
JP (1) JP2011501689A (cg-RX-API-DMAC7.html)
CN (1) CN101932693B (cg-RX-API-DMAC7.html)
DE (2) DE102008008256A1 (cg-RX-API-DMAC7.html)
DK (1) DK2205716T3 (cg-RX-API-DMAC7.html)
WO (1) WO2009046697A2 (cg-RX-API-DMAC7.html)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2459739B1 (en) * 2009-07-30 2016-09-28 Helmholtz-Zentrum für Infektionsforschung GmbH Methods and tests for screening bacterial biofilms
WO2011026559A1 (en) * 2009-09-05 2011-03-10 Lonza Biologics Plc Deepwell plate system with lid
DE102009057223B4 (de) * 2009-12-05 2016-03-24 Chemagen Biopolymer-Technologie Aktiengesellschaft Probengefäßmatrix und deren Herstellungsverfahren
GB201103665D0 (en) * 2011-03-04 2011-04-13 Univ Cardiff Correlative microscopy
US9333471B2 (en) * 2012-04-11 2016-05-10 STAT—Diagnostica & Innovation, S.L. Fluidically integrated magnetic bead beater
US9872448B2 (en) * 2012-08-06 2018-01-23 Council Of Scientific & Industrial Research Bioreactor vessel for large scale growing of plants under aseptic condition
US9550972B2 (en) 2014-09-29 2017-01-24 General Electric Company Devices, systems and methods for automated cell culturing
DE102016116377A1 (de) 2016-09-01 2018-03-01 Rheinisch-Westfälisch Technische Hochschule (RWTH) Aachen Verfahren und Vorrichtung zur Erfassung von Prozessparametern in Flüssigkulturen
WO2018136752A2 (en) * 2017-01-19 2018-07-26 Essen Bioscience, Inc. Methods and apparatus for perfusion and environment control of microplate labware
US11975330B2 (en) * 2017-01-31 2024-05-07 Myriad Women's Health, Inc. Devices for handling laboratory plates and methods of using the same
GB201709140D0 (en) * 2017-06-08 2017-07-26 Vitrolife As Lid for culture dish
WO2019014541A2 (en) * 2017-07-13 2019-01-17 Greiner Bio-One North America, Inc. CULTURE PLATES FOR IMAGING
DE102018112895B4 (de) 2018-05-30 2024-05-08 Presens Precision Sensing Gmbh System, Vorrichtung und Verfahren zur Erfassung mindestens einer Veränderlichen während eines biologisch / chemischen Prozesses
WO2021106015A1 (en) 2019-11-28 2021-06-03 Council Of Scientific And Industrial Research A continuous flow reactor
CN110907420B (zh) * 2019-12-04 2021-07-02 中国科学院过程工程研究所 一种不互溶液-液相间传质平衡时间的测量装置及利用其的测量方法
EP3910051A1 (en) 2020-05-13 2021-11-17 Evonik Operations GmbH Bioreactors for orbitally shaking cell cultures, in particular suspension cultures
JP2022067072A (ja) * 2020-10-19 2022-05-02 Agcテクノグラス株式会社 培養容器
EP3995211A1 (en) * 2020-11-10 2022-05-11 National Health Research Institutes High-efficiency single-cell collection method
WO2022236141A1 (en) 2021-05-07 2022-11-10 Beckman Coulter, Inc. Container assembly for microbioreactor
WO2022235597A1 (en) 2021-05-07 2022-11-10 Beckman Coulter, Inc. Control of ph in parallel culture wells
WO2022236146A1 (en) 2021-05-07 2022-11-10 Beckman Coulter, Inc. Container assembly for microbioreactor
WO2024188448A1 (de) * 2023-03-13 2024-09-19 Hombrechtikon Systems Engineering Ag Behälter, mischungsvorrichtung und verfahren zur verwendung einer mischungsvorrichtung
WO2025136489A1 (en) 2023-12-19 2025-06-26 Beckman Coulter, Inc. Automated system for clone selection based on antibody production and measurement of cell health parameters

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225164A (en) * 1991-09-30 1993-07-06 Astle Thomas W Microplate laboratory tray with rectilinear wells
CA2286195C (en) * 1997-04-09 2006-02-14 Minnesota Mining And Manufacturing Company Method and devices for partitioning biological sample liquids into microvolumes
USD403077S (en) * 1997-05-12 1998-12-22 Neogen Corporation Microorganism culture tray
US6159368A (en) * 1998-10-29 2000-12-12 The Perkin-Elmer Corporation Multi-well microfiltration apparatus
US6896848B1 (en) 2000-12-19 2005-05-24 Tekcel, Inc. Microplate cover assembly
DE10117275B4 (de) * 2001-04-06 2005-02-24 Hte Ag The High Throughput Experimentation Company Vorrichtung zur Archivierung und Analyse von Materialien
EP1395366B1 (en) * 2001-06-14 2006-05-03 Millipore Corporation Multiwell test apparatus
AT500167B1 (de) * 2001-06-18 2007-10-15 Greiner Bio One Gmbh Reaktionsgefäss
US6890488B2 (en) * 2001-06-22 2005-05-10 Matrix Technologies, Inc. Apparatus for sealing test tubes and the like
DE20121739U1 (de) * 2001-10-08 2003-08-28 Mecadi GmbH-Chemicals/Processing, 66424 Homburg Platte für parallelisierte Analysen und Synthesen
DE10159091A1 (de) * 2001-12-01 2003-06-12 Evotec Ag Trägersysteme und Verfahren zu ihrer Herstellung
US8257967B2 (en) * 2002-04-26 2012-09-04 Board Of Regents, The University Of Texas System Method and system for the detection of cardiac risk factors
JP2003344433A (ja) 2002-05-22 2003-12-03 Okutekku:Kk マイクロアレイ、マイクロアレイシステム及び被検物質の測定方法
US7211224B2 (en) * 2002-05-23 2007-05-01 Millipore Corporation One piece filtration plate
EP1508373A3 (de) * 2003-08-19 2005-08-03 Herbener, Heinz-Gerd Probenträger mit Flüssigkeitskanal
DE102004017039A1 (de) 2004-04-02 2005-11-03 Rwth Aachen Verfahren und Vorrichtung zur Erfassung von Prozessparametern von Reaktionsflüssigkeiten in mehreren geschüttelten Mikroreaktoren
JP3978500B2 (ja) * 2005-02-18 2007-09-19 国立大学法人埼玉大学 多種微量試料の注入、移行方法
DE202006004642U1 (de) * 2005-03-29 2006-06-08 Sartorius Ag Mikroarray-Vorrichtung zum Präparieren eines Probenträgers
US20060286003A1 (en) * 2005-06-16 2006-12-21 Desilets Kenneth G Multi-well filter plate with shifted wells and U-bottom receiver plate
EP1944080A1 (de) * 2007-01-11 2008-07-16 F.Hoffmann-La Roche Ag Vorrichtung und Verfahren zum Bewegen einer Flüssigkeit in einer Kavität
US20100203621A1 (en) 2007-07-25 2010-08-12 Panasonic Corporation Biosensor

Also Published As

Publication number Publication date
CN101932693B (zh) 2013-03-27
DE102008008256A1 (de) 2009-04-09
EP2205716B1 (de) 2017-09-27
JP2011501689A (ja) 2011-01-13
EP2205716A2 (de) 2010-07-14
WO2009046697A9 (de) 2009-07-23
CN101932693A (zh) 2010-12-29
DE112008002590A5 (de) 2010-06-24
DE112008002590B4 (de) 2022-02-24
US20100248995A1 (en) 2010-09-30
WO2009046697A3 (de) 2009-09-11
US8828337B2 (en) 2014-09-09
WO2009046697A2 (de) 2009-04-16

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