DK2066669T3 - Adenosinderivater som A2A-receptoragonister - Google Patents
Adenosinderivater som A2A-receptoragonisterInfo
- Publication number
- DK2066669T3 DK2066669T3 DK07803477.4T DK07803477T DK2066669T3 DK 2066669 T3 DK2066669 T3 DK 2066669T3 DK 07803477 T DK07803477 T DK 07803477T DK 2066669 T3 DK2066669 T3 DK 2066669T3
- Authority
- DK
- Denmark
- Prior art keywords
- receptor agonists
- adenosine derivatives
- adenosine
- derivatives
- agonists
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06120706A EP1903044A1 (en) | 2006-09-14 | 2006-09-14 | Adenosine Derivatives as A2A Receptor Agonists |
| PCT/EP2007/059666 WO2008031875A1 (en) | 2006-09-14 | 2007-09-13 | Adenosine derivatives as a2a receptor agonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2066669T3 true DK2066669T3 (da) | 2011-01-10 |
Family
ID=37622170
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07803477.4T DK2066669T3 (da) | 2006-09-14 | 2007-09-13 | Adenosinderivater som A2A-receptoragonister |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US8188100B2 (da) |
| EP (2) | EP1903044A1 (da) |
| JP (1) | JP2010503639A (da) |
| KR (1) | KR20090040386A (da) |
| CN (1) | CN101511831B (da) |
| AR (1) | AR062768A1 (da) |
| AT (1) | ATE481404T1 (da) |
| AU (1) | AU2007296227A1 (da) |
| BR (1) | BRPI0716936A2 (da) |
| CA (1) | CA2662104A1 (da) |
| CL (1) | CL2007002658A1 (da) |
| CR (1) | CR10621A (da) |
| CY (1) | CY1110990T1 (da) |
| DE (1) | DE602007009272D1 (da) |
| DK (1) | DK2066669T3 (da) |
| ES (1) | ES2353141T3 (da) |
| HK (1) | HK1131392A1 (da) |
| HR (1) | HRP20100694T1 (da) |
| IL (1) | IL197153A0 (da) |
| MA (1) | MA30722B1 (da) |
| MX (1) | MX2009002811A (da) |
| NO (1) | NO20091244L (da) |
| PE (1) | PE20081151A1 (da) |
| PL (1) | PL2066669T3 (da) |
| PT (1) | PT2066669E (da) |
| RU (1) | RU2009113668A (da) |
| SI (1) | SI2066669T1 (da) |
| TN (1) | TN2009000084A1 (da) |
| TW (1) | TW200821324A (da) |
| WO (1) | WO2008031875A1 (da) |
| ZA (1) | ZA200901036B (da) |
Families Citing this family (57)
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| WO2003029264A2 (en) * | 2001-10-01 | 2003-04-10 | University Of Virginia Patent Foundation | 2-propynyl adenosine analogs having a2a agonist activity and compositions thereof |
| GT200500281A (es) * | 2004-10-22 | 2006-04-24 | Novartis Ag | Compuestos organicos. |
| US9512125B2 (en) | 2004-11-19 | 2016-12-06 | The Regents Of The University Of California | Substituted pyrazolo[3.4-D] pyrimidines as anti-inflammatory agents |
| GB0500785D0 (en) | 2005-01-14 | 2005-02-23 | Novartis Ag | Organic compounds |
| WO2007120972A2 (en) * | 2006-02-10 | 2007-10-25 | University Of Virginia Patent Foundation | Method to treat sickle cell disease |
| PT2004654E (pt) | 2006-04-04 | 2013-08-27 | Univ California | Derivados de pirazolopirimidina para utilização como antagonistas da quinase |
| GB0607944D0 (en) * | 2006-04-21 | 2006-05-31 | Novartis Ag | Organic compounds |
| MY146645A (en) * | 2006-04-21 | 2012-09-14 | Novartis Ag | Purine derivatives for use as adenosin a2a receptor agonists |
| GB0607953D0 (en) * | 2006-04-21 | 2006-05-31 | Novartis Ag | Organic compounds |
| GB0607950D0 (en) * | 2006-04-21 | 2006-05-31 | Novartis Ag | Organic compounds |
| US8188063B2 (en) | 2006-06-19 | 2012-05-29 | University Of Virginia Patent Foundation | Use of adenosine A2A modulators to treat spinal cord injury |
| US7906518B2 (en) * | 2006-06-27 | 2011-03-15 | Cbt Development Limited | Therapeutic compounds |
| EP1889846A1 (en) | 2006-07-13 | 2008-02-20 | Novartis AG | Purine derivatives as A2a agonists |
| BRPI0718792A2 (pt) * | 2006-11-10 | 2013-12-03 | Novartis Ag | Compostos orgânicos |
| WO2009046448A1 (en) | 2007-10-04 | 2009-04-09 | Intellikine, Inc. | Chemical entities and therapeutic uses thereof |
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| US8058259B2 (en) | 2007-12-20 | 2011-11-15 | University Of Virginia Patent Foundation | Substituted 4-{3-[6-amino-9-(3,4-dihydroxy-tetrahydro-furan-2-yl)-9H-purin-2-yl]-prop-2-ynyl}-piperidine-1-carboxylic acid esters as A2AR agonists |
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| MY159955A (en) | 2008-01-04 | 2017-02-15 | Intellikine Inc | Certain chemical entities, compositions and methods |
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| WO2009114874A2 (en) | 2008-03-14 | 2009-09-17 | Intellikine, Inc. | Benzothiazole kinase inhibitors and methods of use |
| KR20110039326A (ko) | 2008-07-08 | 2011-04-15 | 인텔리카인, 인크. | 키나제 억제제 및 사용 방법 |
| US20110224223A1 (en) | 2008-07-08 | 2011-09-15 | The Regents Of The University Of California, A California Corporation | MTOR Modulators and Uses Thereof |
| CA2738429C (en) | 2008-09-26 | 2016-10-25 | Intellikine, Inc. | Heterocyclic kinase inhibitors |
| DK2358720T3 (da) | 2008-10-16 | 2016-06-06 | Univ California | Heteroarylkinaseinhibitorer med kondenseret ring |
| US8476431B2 (en) | 2008-11-03 | 2013-07-02 | Itellikine LLC | Benzoxazole kinase inhibitors and methods of use |
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| US8980899B2 (en) | 2009-10-16 | 2015-03-17 | The Regents Of The University Of California | Methods of inhibiting Ire1 |
| US8604032B2 (en) | 2010-05-21 | 2013-12-10 | Infinity Pharmaceuticals, Inc. | Chemical compounds, compositions and methods for kinase modulation |
| US8901133B2 (en) | 2010-11-10 | 2014-12-02 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
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| EP2751093A1 (en) | 2011-08-29 | 2014-07-09 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| CA2846496C (en) | 2011-09-02 | 2020-07-14 | The Regents Of The University Of California | Substituted pyrazolo[3,4-d]pyrimidines and uses thereof |
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| CA2886240A1 (en) | 2012-09-26 | 2014-04-03 | The Regents Of The University Of California | Modulation of ire1 |
| US9481667B2 (en) | 2013-03-15 | 2016-11-01 | Infinity Pharmaceuticals, Inc. | Salts and solid forms of isoquinolinones and composition comprising and methods of using the same |
| UA121104C2 (uk) | 2013-10-04 | 2020-04-10 | Інфініті Фармасьютикалз, Інк. | Гетероциклічні сполуки і їх застосування |
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| BRPI0718792A2 (pt) | 2006-11-10 | 2013-12-03 | Novartis Ag | Compostos orgânicos |
| US20080312160A1 (en) | 2007-04-09 | 2008-12-18 | Guerrant Richard L | Method of treating enteritis, intestinal damage, and diarrhea from c. difficile with an a2a adenosine receptor agonist |
| US20080262001A1 (en) | 2007-04-23 | 2008-10-23 | Adenosine Therapeutics, Llc | Agonists of a2a adenosine receptors for treating recurrent tumor growth in the liver following resection |
| US8153781B2 (en) | 2007-06-29 | 2012-04-10 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Dendrimer conjugates of agonists and antagonists of the GPCR superfamily |
| US20090181934A1 (en) | 2007-10-17 | 2009-07-16 | Novartis Ag | Organic Compounds |
| AU2008313789A1 (en) | 2007-10-17 | 2009-04-23 | Novartis Ag | Purine derivatives as adenosine AL receptor ligands |
| US8183225B2 (en) | 2007-11-08 | 2012-05-22 | New York University | Inhibition of bone resorption using medical implants containing adenosine receptor antagonists |
| US20090181920A1 (en) | 2008-01-09 | 2009-07-16 | Pgxhealth, Llc | Intrathecal treatment of neuropathic pain with a2ar agonists |
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2006
- 2006-09-14 EP EP06120706A patent/EP1903044A1/en not_active Ceased
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2007
- 2007-09-12 AR ARP070104040A patent/AR062768A1/es not_active Application Discontinuation
- 2007-09-12 PE PE2007001224A patent/PE20081151A1/es not_active Application Discontinuation
- 2007-09-13 PL PL07803477T patent/PL2066669T3/pl unknown
- 2007-09-13 DK DK07803477.4T patent/DK2066669T3/da active
- 2007-09-13 BR BRPI0716936-1A2A patent/BRPI0716936A2/pt not_active IP Right Cessation
- 2007-09-13 CL CL200702658A patent/CL2007002658A1/es unknown
- 2007-09-13 AT AT07803477T patent/ATE481404T1/de active
- 2007-09-13 MX MX2009002811A patent/MX2009002811A/es not_active Application Discontinuation
- 2007-09-13 CN CN2007800333258A patent/CN101511831B/zh not_active Expired - Fee Related
- 2007-09-13 RU RU2009113668/04A patent/RU2009113668A/ru unknown
- 2007-09-13 ES ES07803477T patent/ES2353141T3/es active Active
- 2007-09-13 DE DE602007009272T patent/DE602007009272D1/de active Active
- 2007-09-13 WO PCT/EP2007/059666 patent/WO2008031875A1/en active Application Filing
- 2007-09-13 EP EP07803477A patent/EP2066669B1/en active Active
- 2007-09-13 US US12/310,254 patent/US8188100B2/en not_active Expired - Fee Related
- 2007-09-13 KR KR1020097005251A patent/KR20090040386A/ko active IP Right Grant
- 2007-09-13 CA CA002662104A patent/CA2662104A1/en not_active Abandoned
- 2007-09-13 PT PT07803477T patent/PT2066669E/pt unknown
- 2007-09-13 TW TW096134289A patent/TW200821324A/zh unknown
- 2007-09-13 SI SI200730448T patent/SI2066669T1/sl unknown
- 2007-09-13 AU AU2007296227A patent/AU2007296227A1/en not_active Abandoned
- 2007-09-13 JP JP2009527828A patent/JP2010503639A/ja not_active Withdrawn
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2009
- 2009-02-13 ZA ZA200901036A patent/ZA200901036B/xx unknown
- 2009-02-19 IL IL197153A patent/IL197153A0/en unknown
- 2009-02-19 CR CR10621A patent/CR10621A/es not_active Application Discontinuation
- 2009-03-13 TN TN2009000084A patent/TN2009000084A1/fr unknown
- 2009-03-25 NO NO20091244A patent/NO20091244L/no not_active Application Discontinuation
- 2009-03-30 MA MA31736A patent/MA30722B1/fr unknown
- 2009-12-03 HK HK09111343.2A patent/HK1131392A1/xx unknown
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2010
- 2010-12-14 HR HR20100694T patent/HRP20100694T1/hr unknown
- 2010-12-15 CY CY20101101154T patent/CY1110990T1/el unknown
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