DK193088A - 2-acylpyrrolidin-derivater, deres fremstilling og anvendelse - Google Patents
2-acylpyrrolidin-derivater, deres fremstilling og anvendelseInfo
- Publication number
- DK193088A DK193088A DK193088A DK193088A DK193088A DK 193088 A DK193088 A DK 193088A DK 193088 A DK193088 A DK 193088A DK 193088 A DK193088 A DK 193088A DK 193088 A DK193088 A DK 193088A
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- acylpyrrolidine derivatives
- acylpyrrolidine
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873712365 DE3712365A1 (de) | 1987-04-11 | 1987-04-11 | Neue 2-acylpyrrolidin-derivate, verfahren zu ihrer herstellung, sie enthaltende mittel sowie deren verwendung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK193088D0 DK193088D0 (da) | 1988-04-08 |
| DK193088A true DK193088A (da) | 1988-10-12 |
Family
ID=6325457
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK193088A DK193088A (da) | 1987-04-11 | 1988-04-08 | 2-acylpyrrolidin-derivater, deres fremstilling og anvendelse |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4912127A (hu) |
| EP (1) | EP0286928A3 (hu) |
| JP (1) | JPS63267755A (hu) |
| KR (1) | KR880012543A (hu) |
| AU (1) | AU607754B2 (hu) |
| DE (1) | DE3712365A1 (hu) |
| DK (1) | DK193088A (hu) |
| FI (1) | FI881613A (hu) |
| HU (1) | HU199784B (hu) |
| IL (1) | IL86027A (hu) |
| NO (1) | NO881544L (hu) |
| PH (1) | PH25713A (hu) |
| PT (1) | PT87195B (hu) |
| ZA (1) | ZA882459B (hu) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3712364A1 (de) * | 1987-04-11 | 1988-10-27 | Hoechst Ag | Neue pyrrolidin-2-(1,3-dicarbonyl)-derivate, verfahren zu ihrer herstellung, sie enthaltende mittel sowie deren verwendung |
| DE3742431A1 (de) * | 1987-12-15 | 1989-07-13 | Hoechst Ag | Neue derivate cyclischer aminosaeuren, verfahren zu ihrer herstellung, sie enthaltende mittel und deren verwendung |
| US5053414A (en) * | 1988-04-08 | 1991-10-01 | Ono Pharmaceutical Co., Ltd. | Heterocyclic compounds |
| JPH0825995B2 (ja) * | 1988-04-08 | 1996-03-13 | 小野薬品工業株式会社 | 複素環化合物 |
| DE3817468A1 (de) * | 1988-05-21 | 1989-11-30 | Hoechst Ag | Ethylenisch ungesaettigte harnstoffderivate und verfahren zu ihrer herstellung |
| US5254696A (en) * | 1990-09-13 | 1993-10-19 | Bayer Aktiengesellschaft | N-acylpyrrolidine derivatives |
| DE4029054A1 (de) * | 1990-09-13 | 1992-03-19 | Bayer Ag | N-acylpyrrolidin-derivate |
| HUT74687A (en) * | 1993-12-02 | 1997-01-28 | Merrell Pharma Inc | Pyrrole and thiazolidine derivatives of prolyl endopeptidase inhibitor activity and pharmaceutical compositions containing the same |
| DE19527574A1 (de) * | 1995-07-28 | 1997-01-30 | Basf Ag | Verfahren zur Herstellung vona-(N,N-Dialkyl)-aminocaarbonsäureamiden |
| AR038967A1 (es) * | 2002-03-18 | 2005-02-02 | Solvay Pharm Bv | Derivados de 2,3 - diaril - pirazolidinas como inhibidores de enzimas que degradan la neurotensina |
| DE602004026289D1 (de) | 2003-05-05 | 2010-05-12 | Probiodrug Ag | Glutaminylcyclase-hemmer |
| US20050137142A1 (en) * | 2003-11-03 | 2005-06-23 | Probiodrug Ag | Combinations useful for the treatment of neuronal disorders |
| EP1713780B1 (en) | 2004-02-05 | 2012-01-18 | Probiodrug AG | Novel inhibitors of glutaminyl cyclase |
| US8524654B2 (en) | 2007-05-21 | 2013-09-03 | The Uab Research Foundation | Prolyl endopeptidase inhibitors for reducing or preventing neutrophilic inflammation |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1492640A (en) * | 1975-07-08 | 1977-11-23 | Ucb Sa | L-pyroglutamyl-l-prolinamide |
| US4560795A (en) * | 1979-04-10 | 1985-12-24 | Merrell Dow France et Cie. | α-Halomethyl derivatives of α-amino acids |
| US4499102A (en) * | 1979-12-13 | 1985-02-12 | Santen Pharmaceutical Co., Ltd. | Thiazolidine and pyrrolidine compounds and pharmaceutical compositions containing them |
| US4277395A (en) * | 1980-06-16 | 1981-07-07 | Richardson-Merrell Inc. | Novel enzyme inhibitors |
| GB2083030B (en) * | 1980-08-23 | 1984-03-07 | Merrell Toraude & Co | Fluorinated pentene diamine derivatives |
| US4456594A (en) * | 1981-11-06 | 1984-06-26 | Smithkline Beckman Corporation | N-Carboxyalkylproline-containing tripeptides |
| US4483991A (en) * | 1983-01-17 | 1984-11-20 | American Home Products Corporation | Hypotensive agents |
| US4518528A (en) * | 1983-05-19 | 1985-05-21 | Rasnick David W | α Amino fluoro ketones |
| JPS6137764A (ja) * | 1984-07-31 | 1986-02-22 | Suntory Ltd | 抗プロリルエンドペプチダ−ゼ活性を有する新規生理活性化合物 |
| JPH0655758B2 (ja) * | 1984-08-24 | 1994-07-27 | 味の素株式会社 | アミノ酸誘導体 |
| US4626545A (en) * | 1984-08-27 | 1986-12-02 | Merck & Co., Inc. | Amino acid derivatives as enzyme inhibitors |
| US4762821A (en) * | 1985-03-22 | 1988-08-09 | Syntex (U.S.A.) Inc. | N',N"-dialkylguanidino dipeptides |
| CA1309805C (en) * | 1985-04-16 | 1992-11-03 | Naoki Higuchi | Dipeptide derivative and synthesis and use thereof |
| JPH0623190B2 (ja) * | 1985-04-16 | 1994-03-30 | サントリー株式会社 | インヒビタ−活性を有するｎ−アシルピロリジン誘導体及びその製法並びに用途 |
| JPH0653757B2 (ja) * | 1985-12-06 | 1994-07-20 | 味の素株式会社 | プロリン誘導体の芳香族スルホン酸塩 |
| JPH08806B2 (ja) * | 1986-11-18 | 1996-01-10 | サントリー株式会社 | プロリルエンドペプチダ−ゼ阻害作用を有する新規ピロリジンアミド誘導体 |
| DE3712363A1 (de) * | 1987-04-11 | 1988-10-27 | Hoechst Ag | Neue pyrrolidin-derivate, verfahren zu ihrer herstellung, sie enthaltende mittel sowie deren verwendung |
| DE3712364A1 (de) * | 1987-04-11 | 1988-10-27 | Hoechst Ag | Neue pyrrolidin-2-(1,3-dicarbonyl)-derivate, verfahren zu ihrer herstellung, sie enthaltende mittel sowie deren verwendung |
-
1987
- 1987-04-11 DE DE19873712365 patent/DE3712365A1/de not_active Withdrawn
-
1988
- 1988-04-01 EP EP19880105332 patent/EP0286928A3/de not_active Withdrawn
- 1988-04-07 FI FI881613A patent/FI881613A/fi not_active Application Discontinuation
- 1988-04-08 ZA ZA882459A patent/ZA882459B/xx unknown
- 1988-04-08 DK DK193088A patent/DK193088A/da not_active Application Discontinuation
- 1988-04-08 NO NO881544A patent/NO881544L/no unknown
- 1988-04-08 US US07/179,292 patent/US4912127A/en not_active Expired - Fee Related
- 1988-04-08 JP JP63085539A patent/JPS63267755A/ja active Pending
- 1988-04-08 PT PT87195A patent/PT87195B/pt not_active IP Right Cessation
- 1988-04-08 HU HU881780A patent/HU199784B/hu not_active IP Right Cessation
- 1988-04-11 AU AU14466/88A patent/AU607754B2/en not_active Ceased
- 1988-04-11 PH PH36780A patent/PH25713A/en unknown
- 1988-04-11 IL IL86027A patent/IL86027A/xx unknown
- 1988-04-11 KR KR1019880004071A patent/KR880012543A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0286928A3 (de) | 1991-05-08 |
| DK193088D0 (da) | 1988-04-08 |
| FI881613A (fi) | 1988-10-12 |
| EP0286928A2 (de) | 1988-10-19 |
| NO881544D0 (no) | 1988-04-08 |
| KR880012543A (ko) | 1988-11-28 |
| IL86027A0 (en) | 1988-09-30 |
| FI881613A0 (fi) | 1988-04-07 |
| PT87195A (pt) | 1988-05-01 |
| IL86027A (en) | 1992-05-25 |
| PT87195B (pt) | 1992-07-31 |
| JPS63267755A (ja) | 1988-11-04 |
| HUT46888A (en) | 1988-12-28 |
| AU1446688A (en) | 1988-10-13 |
| NO881544L (no) | 1988-10-12 |
| PH25713A (en) | 1991-09-18 |
| HU199784B (en) | 1990-03-28 |
| US4912127A (en) | 1990-03-27 |
| ZA882459B (en) | 1988-09-29 |
| DE3712365A1 (de) | 1988-10-27 |
| AU607754B2 (en) | 1991-03-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK609489A (da) | Imidazolderivater, deres fremstilling og anvendelse | |
| DK374289D0 (da) | Indazol-3-carboxylsyrederivater, deres fremstilling og anvendelse | |
| DK605489A (da) | Beta-amino-boronsyre-derivater, deres fremstilling og anvendelse | |
| DK595388D0 (da) | Benzopyranderivater, deres fremstilling og anvendelse | |
| DK193088D0 (da) | 2-acylpyrrolidin-derivater, deres fremstilling og anvendelse | |
| DK633287A (da) | Carbamoylimidazo-derivater, deres fremstilling og anvendelse | |
| DK278188D0 (da) | Thiazolidin-4-on-derivater, deres fremstilling og anvendelse | |
| DK235787D0 (da) | Tripeptidderivater, deres fremstilling og anvendelse | |
| DK189488D0 (da) | Imidazothiadiazinderivater, deres fremstilling og anvendelse | |
| DK213387A (da) | Benzothiazinon-derivater, deres fremstilling og anvendelse | |
| DK469389D0 (da) | Piperidinyl-imidazol-derivater, deres fremstilling og anvendelse | |
| DK212687A (da) | Benzothiazinon-derivater, deres fremstilling og anvendelse | |
| DK162087D0 (da) | Piperidinforbindelser, deres fremstilling og anvendelse | |
| DK223288D0 (da) | Benzensulfornamid-derivater, deres fremstilling og anvendelse | |
| DK610787D0 (da) | Substituerede thienoimidazoltoluidin-derivater, deres fremstilling og anvendelse | |
| DK412188D0 (da) | Benzothiazinon-derivater, deres fremstilling og anvendelse | |
| DK231988A (da) | 2-aminoalkyl-4-benzyl-1-(2h)-phthalazinon-derivater, deres fremstilling og anvendelse | |
| NO885020D0 (no) | Isokinolinderivater, deres fremstilling og anvendelse. | |
| DK193288A (da) | Pyrrolidin-derivater, deres fremstilling og anvendelse | |
| DK613888D0 (da) | Acyllabdan-derivater, deres fremstilling og anvendelse | |
| DK361388D0 (da) | Cephemderivater, deres fremstilling og anvendelse | |
| DK668788A (da) | Labdanderivater, deres fremstilling og anvendelse | |
| DK668888A (da) | Labdan-derivater, deres fremstilling og anvendelse | |
| DK727388D0 (da) | 2-aminotetrahydroisoquinolinderivater, deres fremstilling og anvendelse | |
| DK163589A (da) | Sakyomycin e og derivater deraf, deres fremstilling og anvendelse |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ATS | Application withdrawn |