DK190585A - Fremgangsmaade til fremstilling af cephalosporinderivater - Google Patents
Fremgangsmaade til fremstilling af cephalosporinderivater Download PDFInfo
- Publication number
- DK190585A DK190585A DK190585A DK190585A DK190585A DK 190585 A DK190585 A DK 190585A DK 190585 A DK190585 A DK 190585A DK 190585 A DK190585 A DK 190585A DK 190585 A DK190585 A DK 190585A
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- procedure
- cephalosporine derivatives
- cephalosporine
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Description
hvor R*, B og den brudte linje har de ovenfor angivne betydninger, eller en tilsvarende forbindelse med en gruppe 3 3 -COOR i 4-stilling, (hvor R har den voenfor angivne betydning), samt en tilknyttet anion A , med et hydroxylamin-derivat med formlen
2 hvor R har den ovenfor angivne betydning, eller et salt eller en zwitterion deraf. Processen er særlig værdifuld til fremstilling af ceftazidim i godt udbytte og god renhed. Mellemprodukterne med formel II har i sig selv antibiotisk virkning.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB848410993A GB8410993D0 (en) | 1984-04-30 | 1984-04-30 | Process |
GB8410993 | 1984-04-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
DK190585D0 DK190585D0 (da) | 1985-04-29 |
DK190585A true DK190585A (da) | 1985-10-31 |
Family
ID=10560286
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK190585A DK190585A (da) | 1984-04-30 | 1985-04-29 | Fremgangsmaade til fremstilling af cephalosporinderivater |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0160565A3 (da) |
JP (1) | JPH0699442B2 (da) |
KR (1) | KR920005817B1 (da) |
DK (1) | DK190585A (da) |
ES (1) | ES8706158A1 (da) |
FI (1) | FI89926C (da) |
GB (1) | GB8410993D0 (da) |
PT (1) | PT80369B (da) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5182383A (en) * | 1986-09-10 | 1993-01-26 | Biochemie Gesellschaft M.B.H. | Stable, crystalline form of a cephalosporin intermediate product |
JPH0647172B2 (ja) * | 1987-01-23 | 1994-06-22 | ファナック株式会社 | 自動溶接装置 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS54154786A (en) * | 1978-05-26 | 1979-12-06 | Glaxo Group Ltd | Cephalosporin compound |
IL61458A0 (en) * | 1979-12-07 | 1980-12-31 | Erba Farmitalia | N-substituted thiazolyl derivatives of oximino-substituted cephalosporins, their preparation and pharmalceutical compositions containing them |
JPS5821682A (ja) * | 1981-07-31 | 1983-02-08 | Sankyo Co Ltd | セファロスポリン誘導体 |
FR2533216A1 (fr) * | 1982-09-22 | 1984-03-23 | Toyama Chemical Co Ltd | Nouvelles cephalosporines, et leurs sels |
-
1984
- 1984-04-30 GB GB848410993A patent/GB8410993D0/en active Pending
-
1985
- 1985-04-29 PT PT80369A patent/PT80369B/pt not_active IP Right Cessation
- 1985-04-29 FI FI851689A patent/FI89926C/fi not_active IP Right Cessation
- 1985-04-29 KR KR1019850002877A patent/KR920005817B1/ko not_active IP Right Cessation
- 1985-04-29 DK DK190585A patent/DK190585A/da unknown
- 1985-04-29 ES ES542676A patent/ES8706158A1/es not_active Expired
- 1985-04-29 EP EP85303032A patent/EP0160565A3/en not_active Withdrawn
- 1985-04-30 JP JP60091307A patent/JPH0699442B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
FI89926C (fi) | 1993-12-10 |
FI851689L (fi) | 1985-10-31 |
FI89926B (fi) | 1993-08-31 |
ES8706158A1 (es) | 1987-06-01 |
KR920005817B1 (ko) | 1992-07-20 |
DK190585D0 (da) | 1985-04-29 |
JPH0699442B2 (ja) | 1994-12-07 |
FI851689A0 (fi) | 1985-04-29 |
JPS6117591A (ja) | 1986-01-25 |
PT80369A (en) | 1985-05-01 |
GB8410993D0 (en) | 1984-06-06 |
KR850007430A (ko) | 1985-12-04 |
ES542676A0 (es) | 1987-06-01 |
EP0160565A3 (en) | 1986-12-03 |
PT80369B (pt) | 1987-09-30 |
EP0160565A2 (en) | 1985-11-06 |
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