DK1867732T3 - Reagenser, fremgangsmåder og anordninger til påvisning af analytter - Google Patents

Reagenser, fremgangsmåder og anordninger til påvisning af analytter Download PDF

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Publication number
DK1867732T3
DK1867732T3 DK07018162.3T DK07018162T DK1867732T3 DK 1867732 T3 DK1867732 T3 DK 1867732T3 DK 07018162 T DK07018162 T DK 07018162T DK 1867732 T3 DK1867732 T3 DK 1867732T3
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Denmark
Prior art keywords
fad
electrochemical sensor
glucose
group
radiation
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DK07018162.3T
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English (en)
Inventor
Mark S Vreeke
Mary Ellen Warchal-Windham
Christina Blaschke
Barbara J Mikel
Howard A Cooper
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Bayer Healthcare Llc
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Publication of DK1867732T3 publication Critical patent/DK1867732T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Emergency Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Claims (10)

1. Elektrokemisk sensor, der omfatter: en første elektrode med en overflade; og en anden elektrode, der er koblet til den første elektrode, hvor overfladen af den første elektrode inkluderer et reagens, der omfatter: et enzym, der er udvalgt fra gruppen, der består af et flavoprotein, et quinoprotein eller en kombination deraf; og en mediator, der er udvalgt fra gruppen, der består af:
eller en kombination deraf.
2. Elektrokemisk sensor ifølge krav 1, der yderligere omfatter en polymer, der er udvalgt fra gruppen, der består af carboxymethylcellulose, polyethylenoxid og kombinationer deraf.
3. Elektrokemisk sensor ifølge krav 1, hvor bufferen er udvalgt fra gruppen, der består af natriumphosphat, kaliumphosphat, Hepes, MOPS, TES, Pipes, ACES, BES, Dulbeccos og kombinationer deraf.
4. Elektrokemisk sensor ifølge krav 1, hvor reagenset er stabilt efter eksponering for bestråling.
5. Elektrokemisk sensor ifølge krav 4, hvor bestrålingen er én af elektronstrålebestråling, gammastråling og ultraviolet stråling.
6. Elektrokemisk sensor ifølge krav 1, hvor enzymet er udvalgt fra gruppen, der består af FAD-glucosedehydrogenase, PQQ-glucosedehydrogenase og en kombination deraf.
7. Elektrokemisk sensor til påvisning af en analyt, der omfatter: et flavoproteinenzym; og en mediator, der omfatter:
8. Elektrokemisk sensor ifølge krav 7, der yderligere omfatter en polymer, der er udvalgt fra gruppen, der består af carboxymethylcellulose, polyethylenoxid og kombinationer deraf.
9. Elektrokemisk sensor ifølge krav 7, hvor flavoproteinet er udvalgt fra gruppen, der består af FAD-glucoseoxidase, flavinhexoseoxidase, FAD-glucosedehydrogenase, FAD- lactatoxidase, FAD-kolesteroloxidase, FAD-alkoholoxidase, FAD-d-aminosyreoxidase, FAD-cholinoxidase og kombinationer deraf.
10. Elektrokemisk sensor ifølge krav 7, hvor reagenset er stabilt efter eksponering for bestråling.
DK07018162.3T 2001-09-14 2002-09-09 Reagenser, fremgangsmåder og anordninger til påvisning af analytter DK1867732T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31871601P 2001-09-14 2001-09-14
EP02019843A EP1293574B1 (en) 2001-09-14 2002-09-09 Reagents, methods and devices for detecting analytes

Publications (1)

Publication Number Publication Date
DK1867732T3 true DK1867732T3 (da) 2015-04-27

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ID=23239317

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Application Number Title Priority Date Filing Date
DK02019843T DK1293574T3 (da) 2001-09-14 2002-09-09 Reagenser, fremgangsmåder og indretninger til bestemmelse af analytter
DK07018162.3T DK1867732T3 (da) 2001-09-14 2002-09-09 Reagenser, fremgangsmåder og anordninger til påvisning af analytter

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DK02019843T DK1293574T3 (da) 2001-09-14 2002-09-09 Reagenser, fremgangsmåder og indretninger til bestemmelse af analytter

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Country Link
US (1) US7163616B2 (da)
EP (1) EP1293574B1 (da)
JP (3) JP2003185619A (da)
AU (1) AU2002300939C1 (da)
CA (1) CA2401365C (da)
DE (1) DE60223635T2 (da)
DK (2) DK1293574T3 (da)
ES (2) ES2296856T3 (da)

Families Citing this family (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE227844T1 (de) * 1997-02-06 2002-11-15 Therasense Inc Kleinvolumiger sensor zur in-vitro bestimmung
US6036924A (en) * 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
DE60234597D1 (de) 2001-06-12 2010-01-14 Pelikan Technologies Inc Gerät und verfahren zur entnahme von blutproben
AU2002348683A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
AU2002315180A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Electric lancet actuator
ES2357887T3 (es) * 2001-06-12 2011-05-03 Pelikan Technologies Inc. Aparato para mejorar la tasa de éxito de obtención de sangre a partir de una punción capilar.
DE60234598D1 (de) 2001-06-12 2010-01-14 Pelikan Technologies Inc Selbstoptimierende lanzettenvorrichtung mit adaptationsmittel für zeitliche schwankungen von hauteigenschaften
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
US7004928B2 (en) * 2002-02-08 2006-02-28 Rosedale Medical, Inc. Autonomous, ambulatory analyte monitor or drug delivery device
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7976476B2 (en) * 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7371247B2 (en) * 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7410468B2 (en) * 2002-04-19 2008-08-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7175642B2 (en) 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7226461B2 (en) 2002-04-19 2007-06-05 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with sterility barrier release
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7674232B2 (en) * 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7481776B2 (en) * 2002-04-19 2009-01-27 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7563232B2 (en) * 2002-04-19 2009-07-21 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US7141058B2 (en) * 2002-04-19 2006-11-28 Pelikan Technologies, Inc. Method and apparatus for a body fluid sampling device using illumination
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7491178B2 (en) * 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7368221B2 (en) * 2002-06-17 2008-05-06 Verification Technologies, Inc. Changing light absorption by disruption of conjugation
US7192405B2 (en) * 2002-09-30 2007-03-20 Becton, Dickinson And Company Integrated lancet and bodily fluid sensor
US20040120848A1 (en) * 2002-12-20 2004-06-24 Maria Teodorczyk Method for manufacturing a sterilized and calibrated biosensor-based medical device
US8052926B2 (en) * 2002-12-27 2011-11-08 Roche Diagnostics Operations, Inc. Method for manufacturing a sterilized lancet integrated biosensor
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
US20060195128A1 (en) * 2002-12-31 2006-08-31 Don Alden Method and apparatus for loading penetrating members
US20040126831A1 (en) * 2002-12-31 2004-07-01 Medtronic Minimed, Inc. Functionalization of immobilized proteins
WO2004107964A2 (en) 2003-06-06 2004-12-16 Pelikan Technologies, Inc. Blood harvesting device with electronic control
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
US8148164B2 (en) 2003-06-20 2012-04-03 Roche Diagnostics Operations, Inc. System and method for determining the concentration of an analyte in a sample fluid
US8679853B2 (en) 2003-06-20 2014-03-25 Roche Diagnostics Operations, Inc. Biosensor with laser-sealed capillary space and method of making
PL1642117T3 (pl) * 2003-06-20 2018-11-30 F.Hoffmann-La Roche Ag Pasek odczynnika do paska testowego
US8282576B2 (en) 2003-09-29 2012-10-09 Sanofi-Aventis Deutschland Gmbh Method and apparatus for an improved sample capture device
EP1680014A4 (en) 2003-10-14 2009-01-21 Pelikan Technologies Inc METHOD AND APPARATUS PROVIDING A VARIABLE USER INTERFACE
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
WO2005065414A2 (en) 2003-12-31 2005-07-21 Pelikan Technologies, Inc. Method and apparatus for improving fluidic flow and sample capture
US20050247573A1 (en) * 2004-03-23 2005-11-10 Hideaki Nakamura Biosensors
WO2006011062A2 (en) 2004-05-20 2006-02-02 Albatros Technologies Gmbh & Co. Kg Printable hydrogel for biosensors
EP1765194A4 (en) 2004-06-03 2010-09-29 Pelikan Technologies Inc METHOD AND APPARATUS FOR MANUFACTURING A DEVICE FOR SAMPLING LIQUIDS
RU2007110832A (ru) * 2004-08-24 2008-10-10 БАЙЕР ХЕЛТКЭА ЭлЭлСи (US) Способ определения концентрации анализируемых веществ в пробах, прямо опосредованный ферментами
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
JP4691378B2 (ja) * 2005-03-29 2011-06-01 シーシーアイ株式会社 バイオセンサを用いた基質の測定方法
US20070111196A1 (en) * 2005-08-19 2007-05-17 Javier Alarcon Sterilization of Biosensors
EP3461406A1 (en) 2005-09-30 2019-04-03 Intuity Medical, Inc. Multi-site body fluid sampling and analysis cartridge
US7955484B2 (en) 2005-12-14 2011-06-07 Nova Biomedical Corporation Glucose biosensor and method
DE102006014714B3 (de) * 2006-03-30 2007-05-16 Draegerwerk Ag Elektrochemischer Sensor aufweisend eine Mediator-Verbindung
EP2017607B1 (en) * 2006-04-19 2012-10-03 Panasonic Corporation Biosensor
WO2008036516A1 (en) 2006-09-22 2008-03-27 Bayer Healthcare Llc Biosensor system having enhanced stability and hematocrit performance
US8609180B2 (en) * 2007-12-10 2013-12-17 Bayer Healthcare Llc Method of depositing reagent material in a test sensor
RU2524660C2 (ru) 2007-12-10 2014-07-27 БАЙЕР ХЕЛТКЭА ЭлЭлСи Способ получения медиатора 3-фенилимино-3н-фенотиазина или 3-фенилимино-3н-феноксазина
WO2009076273A1 (en) * 2007-12-10 2009-06-18 Bayer Healthcare Llc Methods and systems for forming reagent with reduced background current
CA2708156C (en) 2007-12-10 2018-01-23 Bayer Healthcare Llc Reagents and methods for detecting analytes
US7678250B2 (en) * 2008-01-22 2010-03-16 Home Diagnostics, Inc. Reagent compositions for use in electrochemical detection
IL197532A0 (en) * 2008-03-21 2009-12-24 Lifescan Scotland Ltd Analyte testing method and system
WO2009126900A1 (en) 2008-04-11 2009-10-15 Pelikan Technologies, Inc. Method and apparatus for analyte detecting device
JP5816080B2 (ja) 2008-05-30 2015-11-17 インテュイティ メディカル インコーポレイテッド 体液採取装置及び採取部位インターフェイス
US10383556B2 (en) 2008-06-06 2019-08-20 Intuity Medical, Inc. Medical diagnostic devices and methods
JP5642066B2 (ja) 2008-06-06 2014-12-17 インテュイティ メディカル インコーポレイテッド 体液の試料内に含まれている検体の存在または濃度を決定する検定を行う方法および装置
DK2373805T3 (da) 2008-12-08 2015-12-07 Bayer Healthcare Llc Reagenssammensætninger med lavt totalt saltindhold og systemer til biosensorer
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US8283347B2 (en) * 2009-06-01 2012-10-09 Bayer Healthcare Llc Redox molecules and methods of making the same
CA2782047C (en) 2009-11-30 2019-10-29 Intuity Medical, Inc. Calibration material delivery devices and methods
EP2333544A1 (de) 2009-12-11 2011-06-15 F. Hoffmann-La Roche AG Sterilisierbare Chemie für Testelemente
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8742063B2 (en) 2010-05-28 2014-06-03 Bayer Healthcare Llc Polymer bonded redox molecules and methods of making the same
US10330667B2 (en) 2010-06-25 2019-06-25 Intuity Medical, Inc. Analyte monitoring methods and systems
JP5698085B2 (ja) * 2010-07-12 2015-04-08 アークレイ株式会社 バイオセンサ及びその製造方法
JP6027972B2 (ja) * 2010-09-23 2016-11-16 アセンシア・ダイアベティス・ケア・ホールディングス・アーゲーＡｓｃｅｎｓｉａ Ｄｉａｂｅｔｅｓ Ｃａｒｅ Ｈｏｌｄｉｎｇｓ ＡＧ 化合物、ポリマー、フィルムコーティング、および医療デバイス
US9594044B2 (en) * 2010-09-30 2017-03-14 Panasonic Healthcare Holdings Co., Ltd. Reagent composition, sensor, sensor system, and sensor manufacture process
EP3407064B1 (en) 2011-08-03 2020-04-22 Intuity Medical, Inc. Body fluid sampling arrangement
JP6152347B2 (ja) * 2012-02-09 2017-06-21 協和メデックス株式会社 ロイコ型色原体含有水溶液の保存方法
JP6170041B2 (ja) * 2012-04-27 2017-07-26 協和メデックス株式会社 血清又は血漿中のアスコルビン酸の安定化方法
US20140262830A1 (en) * 2013-03-13 2014-09-18 The Regents Of The University Of Michigan Method for determining tear glucose concentration with blood glucose test strips
CA2912283A1 (en) 2013-06-21 2014-12-21 Intuity Medical, Inc. Analyte monitoring system with audible feedback

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0078636B2 (en) 1981-10-23 1997-04-02 MediSense, Inc. Sensor for components of a liquid mixture
CA1219040A (en) 1983-05-05 1987-03-10 Elliot V. Plotkin Measurement of enzyme-catalysed reactions
CA1226036A (en) * 1983-05-05 1987-08-25 Irving J. Higgins Analytical equipment and sensor electrodes therefor
US5126247A (en) 1988-02-26 1992-06-30 Enzymatics, Inc. Method, system and devices for the assay and detection of biochemical molecules
WO1989009397A1 (en) 1988-03-31 1989-10-05 Matsushita Electric Industrial Co., Ltd. Biosensor and process for its production
US4941308A (en) 1988-07-25 1990-07-17 Abbott Laboratories Method of packaging for a sterilizable calibratable medical device
US4863016A (en) 1988-07-25 1989-09-05 Abbott Laboratories Packaging for a sterilizable calibratable medical device
DE3826922A1 (de) 1988-08-09 1990-02-22 Boehringer Mannheim Gmbh Verfahren zur kolorimetrischen bestimmung eines analyten mittels enzymatischer oxidation
US5236567A (en) 1989-05-31 1993-08-17 Nakano Vinegar Co., Ltd. Enzyme sensor
JPH06503472A (ja) * 1990-10-10 1994-04-21 ノボ　ノルディスク　アクティーゼルスカブ 電荷移動仲介剤としてのベンゼン誘導体の利用
FI905324A (fi) 1990-10-29 1992-04-30 Valtion Teknillinen Enzymatiskt bestaemningsfoerfarande foer aldoser.
JP3717529B2 (ja) * 1992-03-31 2005-11-16 征夫 軽部 酵素電極用組成物および酵素固定化電極
US5212092A (en) 1992-05-22 1993-05-18 Puritan-Bennett Corporation Storage and calibration solution for multiparameter intravascular blood gas sensor device
US5298144A (en) 1992-09-15 1994-03-29 The Yellow Springs Instrument Company, Inc. Chemically wired fructose dehydrogenase electrodes
ZA938555B (en) * 1992-11-23 1994-08-02 Lilly Co Eli Technique to improve the performance of electrochemical sensors
US5393615A (en) 1994-02-03 1995-02-28 Miles Inc. Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof
JPH07294481A (ja) * 1994-04-25 1995-11-10 Matsushita Electric Ind Co Ltd バイオセンサ
US5520786A (en) * 1995-06-06 1996-05-28 Bayer Corporation Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof
US5801057A (en) 1996-03-22 1998-09-01 Smart; Wilson H. Microsampling device and method of construction
US5723284A (en) * 1996-04-01 1998-03-03 Bayer Corporation Control solution and method for testing the performance of an electrochemical device for determining the concentration of an analyte in blood
DE19639169A1 (de) 1996-09-24 1998-04-02 Boehringer Mannheim Gmbh Redoxaktive Verbindungen und deren Anwendung
US5798031A (en) 1997-05-12 1998-08-25 Bayer Corporation Electrochemical biosensor
US6656697B1 (en) 1998-09-28 2003-12-02 Lifescan, Inc. Diagnostics based on tetrazolium compounds
JP3694424B2 (ja) * 1998-09-29 2005-09-14 松下電器産業株式会社 グルコースセンサ
US6338790B1 (en) * 1998-10-08 2002-01-15 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
JP2000116629A (ja) * 1998-10-15 2000-04-25 Kdk Corp 装着体
JP4352108B2 (ja) * 1998-12-15 2009-10-28 アークレイ株式会社 基質の定量方法
US6360888B1 (en) * 1999-02-25 2002-03-26 Minimed Inc. Glucose sensor package system
EP1238632B1 (en) * 1999-12-13 2011-05-11 ARKRAY, Inc. Body fluid measuring apparatus with lancet and lancet holder used for the measuring apparatus
US6562210B1 (en) * 1999-12-30 2003-05-13 Roche Diagnostics Corporation Cell for electrochemical anaylsis of a sample
US6706159B2 (en) * 2000-03-02 2004-03-16 Diabetes Diagnostics Combined lancet and electrochemical analyte-testing apparatus

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Publication number Publication date
CA2401365C (en) 2013-12-31
EP1293574A3 (en) 2004-03-03
DE60223635D1 (de) 2008-01-03
DK1293574T3 (da) 2008-03-10
EP1293574A2 (en) 2003-03-19
AU2002300939C1 (en) 2009-03-05
AU2002300939B2 (en) 2008-10-23
JP2012154955A (ja) 2012-08-16
JP2009025318A (ja) 2009-02-05
JP5275494B2 (ja) 2013-08-28
CA2401365A1 (en) 2003-03-14
US7163616B2 (en) 2007-01-16
EP1293574B1 (en) 2007-11-21
ES2296856T3 (es) 2008-05-01
US20030094384A1 (en) 2003-05-22
JP2003185619A (ja) 2003-07-03
ES2535286T3 (es) 2015-05-08
DE60223635T2 (de) 2008-10-30

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