DK186589A - E. coli-stamme til kraftig sekretion af protein til dyrkningsmediet, dens fremstilling og anvendelse - Google Patents

E. coli-stamme til kraftig sekretion af protein til dyrkningsmediet, dens fremstilling og anvendelse

Info

Publication number
DK186589A
DK186589A DK186589A DK186589A DK186589A DK 186589 A DK186589 A DK 186589A DK 186589 A DK186589 A DK 186589A DK 186589 A DK186589 A DK 186589A DK 186589 A DK186589 A DK 186589A
Authority
DK
Denmark
Prior art keywords
secretion
stems
coli
powerful
protein
Prior art date
Application number
DK186589A
Other languages
English (en)
Other versions
DK186589D0 (da
DK174508B1 (da
Inventor
August Boeck
Wiebke Seydel
Gerhard Schmid
Gabriele Mueller
Original Assignee
Consortium Elektrochem Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consortium Elektrochem Ind filed Critical Consortium Elektrochem Ind
Publication of DK186589D0 publication Critical patent/DK186589D0/da
Publication of DK186589A publication Critical patent/DK186589A/da
Application granted granted Critical
Publication of DK174508B1 publication Critical patent/DK174508B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C12N9/1074—Cyclomaltodextrin glucanotransferase (2.4.1.19)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C12R2001/19—Escherichia coli

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Led Devices (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK198901865A 1988-04-19 1989-04-18 Fremgangsmåde til fremstilling af en E. coli-stamme til proteinsekretion af mindst 140 mg protein pr. liter i løbet af 48 timer i dyrkningsmediet, ved fremgangsmåden fremstillelig E. coli-stamme og dennes anvendelse DK174508B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3813107 1988-04-19
DE3813107A DE3813107A1 (de) 1988-04-19 1988-04-19 Sekretormutante von escherichia coli

Publications (3)

Publication Number Publication Date
DK186589D0 DK186589D0 (da) 1989-04-18
DK186589A true DK186589A (da) 1989-10-20
DK174508B1 DK174508B1 (da) 2003-05-05

Family

ID=6352379

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198901865A DK174508B1 (da) 1988-04-19 1989-04-18 Fremgangsmåde til fremstilling af en E. coli-stamme til proteinsekretion af mindst 140 mg protein pr. liter i løbet af 48 timer i dyrkningsmediet, ved fremgangsmåden fremstillelig E. coli-stamme og dennes anvendelse

Country Status (6)

Country Link
EP (1) EP0338410B1 (da)
JP (1) JP3040402B2 (da)
AT (1) ATE112320T1 (da)
DE (2) DE3813107A1 (da)
DK (1) DK174508B1 (da)
FI (1) FI102544B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4009268A1 (de) * 1990-03-22 1991-09-26 Consortium Elektrochem Ind Sekretion von hirudinderivaten
US6514730B1 (en) 1991-03-21 2003-02-04 Consortium für elektrochemische Industrie GmbH Secretion of hirudin derivatives
DE4113750A1 (de) 1991-04-26 1992-10-29 Boehringer Mannheim Gmbh Verbesserung der renaturierung bei der sekretion von disulfidverbrueckten proteinen
US5830692A (en) * 1995-03-24 1998-11-03 Consortium Fur Elektrochemische Industrie Gmbh Expression system which can be regulated
EP0826899B1 (en) 1996-08-30 2006-02-01 Aisin Seiki Kabushiki Kaisha Power transmitting mechanism
AU4424597A (en) * 1996-09-13 1998-04-02 Novo Nordisk Biotech, Inc. Cells having dna insertion mutations which produce altered amounts of a polypeptide
DE102006004871A1 (de) 2006-02-02 2007-08-09 Wacker Chemie Ag Mikroorganismenstamm zur Produktion von rekombinanten Proteinen
ATE465241T1 (de) * 2006-09-22 2010-05-15 Wacker Chemie Ag Verfahren zur fermentativen herstellung von proteinen
DE102006044841A1 (de) 2006-09-22 2008-04-03 Wacker Chemie Ag Signalpeptid zur Produktion von rekombinanten Proteinen
DE502006009060D1 (de) 2006-09-22 2011-04-21 Wacker Chemie Ag Verfahren zur fermentativen Herstellung von Antikörpern
DE102006050332A1 (de) 2006-10-25 2008-04-30 Wacker Chemie Ag DNS-Konstrukt und Verfahren zur fermentativen Herstellung von Fusionsproteinen
WO2009021548A1 (en) * 2007-08-10 2009-02-19 Wacker Chemie Ag Expression of full length igg and secretion into the culture medium of prokaryotic cells

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0071485B1 (en) * 1981-07-30 1989-09-20 Akira Kimura Novel microorganisms derived from microorganisms of the genus escherichia by mutation and their use in the preparation of glutathione
JPS62166881A (ja) * 1986-01-16 1987-07-23 Michio Matsuhashi 大腸菌のペリプラズム蛋白質分泌変異株
ATE122391T1 (de) * 1987-01-30 1995-05-15 Harvard College Periplasmische protease-mutanten von escherichia coli.

Also Published As

Publication number Publication date
DK186589D0 (da) 1989-04-18
EP0338410A3 (de) 1991-10-16
JP3040402B2 (ja) 2000-05-15
EP0338410B1 (de) 1994-09-28
FI891832A (fi) 1989-10-20
FI102544B1 (fi) 1998-12-31
DK174508B1 (da) 2003-05-05
JPH0235077A (ja) 1990-02-05
DE58908428D1 (de) 1994-11-03
DE3813107A1 (de) 1989-11-02
FI102544B (fi) 1998-12-31
FI891832A0 (fi) 1989-04-18
EP0338410A2 (de) 1989-10-25
ATE112320T1 (de) 1994-10-15

Similar Documents

Publication Publication Date Title
DK219087A (da) Vektorsystem til brug ved transformation af trichoderma, transformerede trichodermastammer og fremgangsmaade til fremstilling af proteiner heri
DK186589D0 (da) E. coli-stamme til kraftig sekretion af protein til dyrkningsmediet, dens fremstilling og anvendelse
DE3876453T2 (de) Methode zur kontrolle von staubbildung.
DE3884529D1 (de) Leader-anteile zur produktion von rekombinanten proteinen.
DE69731285D1 (de) Langwellig fluorezierende proteine
NO823674L (no) Derivater av cis, endo-2-azabicyklo-(3.3.0)-oktan-3-3-karboksylsyrer, fremgangsmaate til deres fremstilling, midler inneholdende disse og deres anvendelse
NO168538C (no) Fremgangsmaate for fremstilling av humant leukocytt-interferon av typen ifn-alfa 2(arg) ved hjelp av mikroorganismer som koder for disse.
SE8803071L (sv) Bakteriebehandling foer att bevara hoekvalitet genom att tillaegga genius bacillus mikroorganismer
DK98192D0 (da) Triphenylmethyl-derivater af sn-glycero-3-phosphocholin og sn-glycero-3-phosphoethanolamin og fremgangsmaade til fremstilling deraf
NO864858L (no) Optisk ren forbindelse og fremgangsmaate for dens fremstilling.
DE68922665T2 (de) Methode zur optischen Kopplung.
DK10288A (da) Fremgangsmaade til isolering og rensning af p. falciparum cs-proteinvaccine udtrykt i rekombineret e. coli
NO911557L (no) Fremgangsmaate for fremstilling av fremmedproteiner i streptomyceter.
DK560686D0 (da) Fremgangsmaade til fremstilling af proteiner ved hjaelp af vaertsorganismer, fortrinsvis maelkesyrebakterier
ES514528A0 (es) Un procedimiento para la produccion de una proteina de fusion.
DK0528955T3 (da) Proteasedeficiente bakterielle værtsorganismer
KR900700604A (ko) 오이 모자이크 바이러스 코트 단백질 유전자
CO4230106A1 (es) Proceso para la preparacion de una nueva aminopeptidasa y su proteina
DK0504798T3 (da) Fremgangsmåde til fremstilling af glutarylacylase i store mængder
DK160270C (da) Fremgangsmaade til fremstilling af 2,4- eller 2,4,5-substituerede 6-hydroxypyrimidiner
SE8403929L (sv) Rekombinant-dna-molekyl, transformerade mikroorganismer och forfarande for framstellning av penicillin v-amidas
FI895108A0 (fi) Koleravacciner.
DK628188D0 (da) Protein og fremgangsmaade til fremstilling deraf
DE3882842D1 (de) Methode zur herstellung von cineolen.
NO881779D0 (no) Fremstilling av l-fenylalanin med hjelp av rekombinante bakterier.

Legal Events

Date Code Title Description
PUP Patent expired