DK185977A - Fremgangsmade til fremstilling af 1,3-dihydroheteroarylspiro (isobenzofuraner) - Google Patents
Fremgangsmade til fremstilling af 1,3-dihydroheteroarylspiro (isobenzofuraner)Info
- Publication number
- DK185977A DK185977A DK185977A DK185977A DK185977A DK 185977 A DK185977 A DK 185977A DK 185977 A DK185977 A DK 185977A DK 185977 A DK185977 A DK 185977A DK 185977 A DK185977 A DK 185977A
- Authority
- DK
- Denmark
- Prior art keywords
- isobenzofuranes
- dihydroheteroarylspiro
- procedure
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/681,509 US4031224A (en) | 1976-04-29 | 1976-04-29 | 1,3-Dihydro-heteroarylspiro (isobenzofuran)s |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK185977A true DK185977A (da) | 1977-10-30 |
Family
ID=24735573
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK185977A DK185977A (da) | 1976-04-29 | 1977-04-28 | Fremgangsmade til fremstilling af 1,3-dihydroheteroarylspiro (isobenzofuraner) |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4031224A (fi) |
| JP (1) | JPS52133974A (fi) |
| AT (1) | AT368502B (fi) |
| AU (1) | AU517471B2 (fi) |
| BE (1) | BE854133A (fi) |
| CA (1) | CA1084493A (fi) |
| DE (1) | DE2718455A1 (fi) |
| DK (1) | DK185977A (fi) |
| ES (1) | ES458127A1 (fi) |
| FI (1) | FI771337A (fi) |
| FR (1) | FR2349587A1 (fi) |
| GB (1) | GB1571077A (fi) |
| GR (1) | GR71645B (fi) |
| IE (1) | IE45037B1 (fi) |
| IL (1) | IL51957A0 (fi) |
| IT (1) | IT1113573B (fi) |
| LU (1) | LU77215A1 (fi) |
| NL (1) | NL7704425A (fi) |
| NO (1) | NO771442L (fi) |
| PT (1) | PT66492B (fi) |
| SE (1) | SE7704857L (fi) |
| ZA (1) | ZA772548B (fi) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4409229A (en) * | 1977-12-02 | 1983-10-11 | Hoechst-Roussel Pharmaceuticals, Inc. | Antidepressive and tranquilizing substituted 1,3-dihydrospiro[benzo(c)thiophene]s |
| IL59444A0 (en) * | 1979-02-22 | 1980-05-30 | Wellcome Found | Imidazole derivatives and salts thereof,their preparation and pharmaceutical compositions containing them |
| US4263317A (en) * | 1979-09-06 | 1981-04-21 | Hoechst-Roussel Pharmaceuticals, Inc. | Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]s |
| US5206240A (en) * | 1989-12-08 | 1993-04-27 | Merck & Co., Inc. | Nitrogen-containing spirocycles |
| EP0450761A1 (en) * | 1990-03-02 | 1991-10-09 | Merck & Co. Inc. | Spirocyclic oxytocin antagonists |
| US5648352A (en) * | 1991-09-13 | 1997-07-15 | Merck & Co., Inc. | Piperazinylcamphorsulfonyl oxytocin antagonists |
| US5693643A (en) * | 1991-09-16 | 1997-12-02 | Merck & Co., Inc. | Hydantoin and succinimide-substituted derivatives of spiroindanylcamphorsulfonyl oxytocin antagonists |
| WO1998053823A1 (en) * | 1997-05-29 | 1998-12-03 | Eli Lilly And Company | 5-HT1A AND 5-HT1Dα ANTAGONISTS |
| US6376505B1 (en) | 1997-05-29 | 2002-04-23 | Eli Lilly And Company | 5-HT1A and 5-HT1Dαdalpha antagonists |
| US8785634B2 (en) * | 2010-04-26 | 2014-07-22 | Merck Sharp & Dohme Corp | Spiropiperidine prolylcarboxypeptidase inhibitors |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3959475A (en) * | 1973-12-12 | 1976-05-25 | American Hoechst Corporation | Substituted 1,3-dihydrospiro(isobenzofuran)s |
| US3980787A (en) * | 1975-08-25 | 1976-09-14 | American Hoechst Corporation | 3-Phenylspiro[isobenzofuran-1,4'-piperidine]sulfenamides and derivatives |
-
1976
- 1976-04-29 US US05/681,509 patent/US4031224A/en not_active Expired - Lifetime
-
1977
- 1977-04-22 NL NL7704425A patent/NL7704425A/xx not_active Application Discontinuation
- 1977-04-23 ES ES458127A patent/ES458127A1/es not_active Expired
- 1977-04-26 NO NO771442A patent/NO771442L/no unknown
- 1977-04-26 DE DE19772718455 patent/DE2718455A1/de not_active Withdrawn
- 1977-04-27 SE SE7704857A patent/SE7704857L/xx unknown
- 1977-04-27 GR GR53305A patent/GR71645B/el unknown
- 1977-04-27 LU LU77215A patent/LU77215A1/xx unknown
- 1977-04-27 IL IL51957A patent/IL51957A0/xx unknown
- 1977-04-27 FI FI771337A patent/FI771337A/fi not_active Application Discontinuation
- 1977-04-27 IT IT22899/77A patent/IT1113573B/it active
- 1977-04-28 ZA ZA00772548A patent/ZA772548B/xx unknown
- 1977-04-28 GB GB17786/77A patent/GB1571077A/en not_active Expired
- 1977-04-28 CA CA277,261A patent/CA1084493A/en not_active Expired
- 1977-04-28 AT AT0302677A patent/AT368502B/de not_active IP Right Cessation
- 1977-04-28 JP JP4976977A patent/JPS52133974A/ja active Pending
- 1977-04-28 IE IE856/77A patent/IE45037B1/en unknown
- 1977-04-28 AU AU24647/77A patent/AU517471B2/en not_active Expired
- 1977-04-28 DK DK185977A patent/DK185977A/da unknown
- 1977-04-28 PT PT66492A patent/PT66492B/pt unknown
- 1977-04-29 BE BE177158A patent/BE854133A/xx unknown
- 1977-04-29 FR FR7713019A patent/FR2349587A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| PT66492A (de) | 1977-05-01 |
| JPS52133974A (en) | 1977-11-09 |
| FI771337A (fi) | 1977-10-30 |
| AT368502B (de) | 1982-10-25 |
| AU2464777A (en) | 1978-11-02 |
| PT66492B (de) | 1978-12-14 |
| GB1571077A (en) | 1980-07-09 |
| IE45037B1 (en) | 1982-06-02 |
| LU77215A1 (fi) | 1977-12-01 |
| CA1084493A (en) | 1980-08-26 |
| GR71645B (fi) | 1983-06-29 |
| FR2349587A1 (fr) | 1977-11-25 |
| SE7704857L (sv) | 1977-10-30 |
| NO771442L (no) | 1977-11-01 |
| IE45037L (en) | 1977-10-29 |
| NL7704425A (nl) | 1977-11-01 |
| AU517471B2 (en) | 1981-08-06 |
| FR2349587B1 (fi) | 1980-03-07 |
| IL51957A0 (en) | 1977-06-30 |
| BE854133A (fr) | 1977-10-31 |
| DE2718455A1 (de) | 1977-11-10 |
| ZA772548B (en) | 1978-04-26 |
| ES458127A1 (es) | 1978-11-01 |
| ATA302677A (de) | 1982-02-15 |
| IT1113573B (it) | 1986-01-20 |
| US4031224A (en) | 1977-06-21 |
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